Research graph
References from Reactive Oxygen Species and p38 Mitogen-activated Protein Kinase Mediate Exercise-induced Skeletal Muscle-derived Interleukin-6 Expression. Local targets link to admitted publications; unresolved targets remain external evidence.
Signaling specificity of interleukin-6 action on glucose and lipid metabolism in skeletal muscle
10.1210/me.2005-0490 · 2006 · External reference
IL6 as a mediator of insulin resistance: fat or fiction?
10.1007/s00125-009-1627-x · 2010 · External reference
Interleukin-6 increases insulin-stimulated glucose disposal in humans and glucose uptake and fatty acid oxidation in vitro via AMP-activated protein kinase
10.2337/db05-1404 · 2006 · External reference
Blockade of the p38 mitogen-activated protein kinase pathway inhibits inducible nitric oxide synthase and interleukin-6 expression in MC3T3E-1 osteoblasts
10.1006/phrs.2000.0778 · 2001 · External reference
Altering dietary nutrient intake that reduces glycogen content leads to phosphorylation of nuclear p38 MAP kinase in human skeletal muscle: association with IL-6 gene transcription during contraction
10.1096/fj.03-1039fje · 2004 · External reference
Oleate reverses palmitate-induced insulin resistance and inflammation in skeletal muscle cells
10.1074/jbc.m708700200 · 2008 · External reference
Interleukin-6 in acute exercise and training: what is the biological relevance?
2006 · External reference
Supplementation with vitamins C and E inhibits the release of interleukin-6 from contracting human skeletal muscle
10.1113/jphysiol.2004.066779 · 2004 · External reference
Interleukins and exercise
10.1111/j.1469-7793.2000.00001.x · 2000 · External reference
Palmitate-induced interleukin 6 production is mediated by protein kinase C and nuclear-factor kappaB activation and leads to glucose transporter 4 down-regulation in skeletal muscle cells
10.1210/en.2004-1560 · 2005 · External reference
Transcriptional activation of the IL-6 gene in human contracting skeletal muscle: influence of muscle glycogen content
10.1096/fj.01-0507fje · 2001 · External reference
Interleukin-6 depletion selectively improves hepatic insulin action in obesity
10.1210/en.2004-1468 · 2005 · External reference
Production of interleukin-6 by skeletal myotubes: role of reactive oxygen species
10.1165/ajrcmb.26.5.4598 · 2002 · External reference
Effect of pre-exercise carbohydrate ingestion on plasma cytokine, stress hormone, and neutrophil degranulation responses to continuous, high-intensity exercise
10.1123/ijsnem.13.4.436 · 2003 · External reference
The effects of pre-exercise high carbohydrate meals with different glycemic indices on blood leukocyte redistribution, IL-6, and hormonal responses during a subsequent prolonged exercise
10.1123/ijsnem.14.6.647 · 2004 · External reference
Carbohydrate ingestion influences skeletal muscle cytokine mRNA and plasma cytokine levels after a 3-h run
10.1152/japplphysiol.01130.2002 · 2003 · External reference
Muscles and their myokines
10.1242/jeb.048074 · 2011 · External reference
Muscle as an endocrine organ: focus on muscle-derived interleukin-6
10.1152/physrev.90100.2007 · 2008 · External reference
Exercise and cytokines with particular focus on muscle-derived IL-6
2001 · External reference
Acute IL-6 treatment increases fatty acid turnover in elderly humans in vivo and in tissue culture in vitro
10.1152/ajpendo.00257.2004 · 2005 · External reference
Redox signaling: hydrogen peroxide as intracellular messenger
10.1038/emm.1999.9 · 1999 · External reference
ERK and p38 MAPK, but not NF-kappaB, are critically involved in reactive oxygen species-mediated induction of IL-6 by angiotensin II in cardiac fibroblasts
10.1161/hh2001.098873 · 2001 · External reference
Interleukin-6 production in contracting human skeletal muscle is influenced by pre-exercise muscle glycogen content
10.1111/j.1469-7793.2001.00633.x · 2001 · External reference
IL-6 enhances plasma IL-1ra, IL-10, and cortisol in humans
10.1152/ajpendo.00074.2003 · 2003 · External reference
Production of interleukin-6 in contracting human skeletal muscles can account for the exercise-induced increase in plasma interleukin-6
10.1111/j.1469-7793.2000.00237.x · 2000 · External reference
The study on the mechanism of low muscle glycogen content stimulates exercise-induced IL-6 gene transcription in rat muscle
2007 · External reference
Interleukin-6-deficient mice develop mature-onset obesity
10.1038/nm0102-75 · 2002 · External reference
Palmitate, but not unsaturated fatty acids, induces the expression of interleukin-6 in human myotubes through proteasome-dependent activation of nuclear factor-kappaB
10.1074/jbc.m312692200 · 2004 · External reference
