Research graph
References from Strain-Release Driven, Lewis Acid-Catalyzed, and Hexafluoroisopropanol-Mediated Reactions of Bicyclo[1.1.0]butanes. Local targets link to admitted publications; unresolved targets remain external evidence.
Lewis Acid-Catalyzed Diastereoselective Carbofunctionalization of Bicyclobutanes Employing Naphthols
10.1039/d3sc01373a · 2023 · External reference
Lewis Acid-Catalyzed 1,3-Dipolar Cycloaddition of Bicyclobutanes with Isatogens: Access to Tetracyclic 2-Oxa-3- azabicyclo[3.1.1]heptanes
10.1021/jacsau.4c00839 · 2025 · External reference
Lewis Acid-Catalyzed Unusual (4 + 3) Annulation of para-Quinone Methides with Bicyclobutanes: Access to Oxabicyclo[4.1.1]octanes
10.1002/anie.202408610 · 2024 · External reference
Simultaneous Activation of Bicyclobutanes and Indolyl Alcohols with HFIP: Access to Indole-Fused Bicyclo[3.1.1]Heptanes
10.1002/anie.202501655 · 2025 · External reference
Strain Release - an Old Tool for New Transformations
10.1039/d0cc01771j · 2020 · External reference
Click Chemistry: Straining to React
10.1038/nchem.2485 · 2016 · External reference
Ueber Polyacetylenverbindungen
10.1002/cber.18850180296 · 1885 · External reference
The Concept of Strain in Organic Chemistry
10.1002/anie.198603121 · 1986 · External reference
Evaluation of Strain in Hydrocarbons. The Strain in Adamantane and its Origin
10.1021/ja00711a030 · 1970 · External reference
10.1002/9781118978429
10.1002/9781118978429 · 2015 · External reference
Electrophilic Cyclopropanes in Organic Synthesis
10.1021/ar50134a004 · 1979 · External reference
Use of cyclopropanes and their derivatives in organic synthesis
10.1021/cr00091a005 · 1989 · External reference
Recent Developments of Cyclopropene Chemistry
10.1039/c1cs15074j · 2011 · External reference
Recent Developments in Cyclopropene Chemistry
10.1039/d0cc01612h · 2020 · External reference
C–C Bond Cleavages of Cyclopropenes: Operating for Selective Ring-Opening Reactions
10.1021/acs.chemrev.0c00151 · 2021 · External reference
Recent developments in the synthesis and reactivity of methylene- and alkylidenecyclopropane derivatives
10.1016/j.tet.2014.04.057 · 2014 · External reference
Visible-light-induced reactions of methylene cyclopropanes (MCPs)
10.1039/d2cc06957a · 2023 · External reference
2H-Azirines: Recent Progress in Synthesis and Applications
10.1002/ejoc.202301292 · 2024 · External reference
Recent advances in 2H-azirine chemistry
10.1016/j.tet.2013.02.020 · 2013 · External reference
2H-Azirines as Synthetic Tools in Organic Chemistry
10.1002/1099-0690(200107)2001:13<2401::aid-ejoc2401>3.0.co;2-u · 2001 · External reference
Bicyclo[2.1.0]pentanes and Bicyclo[2.2.0]hexanes
2009 · External reference
Building the Housane: Diastereoselective Synthesis and Characterization of Bicyclo[2.1.0]pentane Carboxylic Acids
10.1021/acs.joc.9b03044 · 2020 · External reference
Bicyclobutanes: From Curiosities to Versatile Reagents and Covalent Warheads
10.1039/d2sc03948f · 2022 · External reference
Bicyclobutanes as Unusual Building Blocks for Complexity Generation in Organic Synthesis
10.1038/s42004-022-00811-3 · 2023 · External reference
Strain-release transformations of bicyclo[1.1.0]butanes and [1.1.1]propellanes
10.1016/j.tchem.2024.100070 · 2024 · External reference
Recent Advances in the Strain-Release Driven Reactions of Bicyclobutanes: An Emerging Landscape in Organic Synthesis
10.1039/d6cs00010j · 2026 · External reference
Catalytic Strain-Release Enabled Cycloaddition of Carbonyl Activated Bicyclo[1.1.0]butanes
10.1039/d5cs01224d · 2026 · External reference
Small Ring Propellanes
10.1021/cr00095a001 · 1989 · External reference
Rationalizing the Diverse Reactivity of [1.1.1]Propellane through σ–π-Delocalization
10.1039/d0sc01386b · 2020 · External reference
Propellanes - from a chemical curiosity to “explosive” materials and natural products
10.1002/anie.201603951 · 2017 · External reference
Nuclear Magnetic Resonance Spectra in Liquid Crystals and Molecular Structure
10.1021/ar50039a001 · 1971 · External reference
X-ray and theoretical analysis of the relationship between substituent steric effects and the structure of bicyclo[1.1.0]butane. The unexpected flexibility of the bicyclo[1.1.0]butane skeleton
10.1021/ja00356a025 · 1983 · External reference
The Electronic Structure and Reactivity of Small Ring Compounds. I. Bicyclobutane
10.1021/ja00969a015 · 1966 · External reference
Ring-Strain-Enabled Reaction Discovery: New Heterocycles from Bicyclo[1.1.0]butanes
10.1021/ar500437h · 2015 · External reference
Palladium-Catalyzed Strain-Enabled [2π + 2σ] Cycloadditions of Vinyl Bicyclo[1.1.0]Butanes with Methyleneindolinones
10.1021/acs.orglett.4c04224 · 2025 · External reference
Structure-Dependent, Switchable Alder-Ene/[2π + 2σ] Cycloadditions of Vinyl Bicyclo[1.1.0]Butanes with α-Ketoesters Enabled by Palladium Catalysis
10.1021/acs.orglett.4c04251 · 2024 · External reference
Strain-Release Photocatalysis
10.1021/jacs.3c08206 · 2023 · External reference
Visible light-induced strain-release transformations of bicycle[1.1.0]butanes
10.1039/d4gc03193h · 2024 · External reference
State-of-the-art strategies for Lewis acid-catalyzed strain-release cycloadditions of bicyclo[1.1.0]butanes (BCBs)
10.1039/d4qo01741b · 2024 · External reference
HFIP-promoted synthesis of bicyclo[2.1.1]hexanes through formal [2π+2σ] cycloaddition of bicyclo[1.1.0]butanes with α-cyano chalcones
10.1039/d5cc01838b · 2025 · External reference
HFIP-Mediated Spiro-annulation of Bicyclo[1.1.0]butanes with α-Halo Hydroxamates: Access to Functionalized Spirocyclobutenes
10.1021/acs.orglett.5c02493 · 2025 · External reference
Catalytic Asymmetric Strategies for Bicyclo[1.1.0]butane Transformations: Advances and Applications
10.31635/ccschem.025.202505825 · 2025 · External reference
Recent Advances in Catalytic Asymmetric Transformations of Bicyclobutane: A Versatile Building Block for Enantiopure Bioisosteric Molecules
10.1021/acscatal.5c01900 · 2025 · External reference
Synthesis of Cyclobutanes and Cyclobutenes by Strain-Release-Driven Ring-Opening of Bicyclo[1.1.0]butanes
10.1055/a-2402-6920 · 2024 · External reference
Enantioselective Synthesis of Chiral Cyclobutenes Enabled by Brønsted Acid-Catalyzed Isomerization of BCBs
10.1021/jacs.3c06525 · 2023 · External reference
Dimerisation of Aryl-substituted Bicyclobutanes (BCBs): Revealing a New Mode of 1,3-Dipolar Background Reactivity
10.1039/d6sc01258b · 2026 · External reference
Heteroannulation of Bicyclobutane Derivatives via Au-Catalyzed Hydration to Enol Ethers and Intramolecular Cyclization Giving Spirocyclobutanes
10.1039/d3cc01955a · 2023 · External reference
Strain enabled radical spirocyclization cascades: rapid access to spirocyclobutyl lactones and – lactams
10.1039/d3sc05700c · 2024 · External reference
Employing Arynes in Diels-Alder Reactions and Transition-Metal-Free Multicomponent Coupling and Arylation Reactions
10.1021/acs.accounts.6b00188 · 2016 · External reference
Unresolved reference
2021 · External reference
Stereoselective Alder-Ene Reactions of Bicyclo[1.1.0]butanes: Facile Synthesis of Cyclopropyl- and Aryl-Substituted Cyclobutenes
10.1021/jacs.3c13080 · 2024 · External reference
Exploiting Heavier Organochalcogen Compounds in Donor-Acceptor Cyclopropane Chemistry
10.1021/acs.accounts.1c00023 · 2021 · External reference
Catalytic Enantioselective Ring-Opening Reactions of Cyclopropanes
10.1021/acs.chemrev.0c00109 · 2021 · External reference
Asymmetric Catalytic Reactions of Donor-Acceptor Cyclopropanes
10.1002/anie.202006736 · 2021 · External reference
Donor-Acceptor Cyclopropanes in the Synthesis of Carbocycles
10.1002/tcr.201800166 · 2019 · External reference
Donor-Acceptor-Substituted Cyclopropane Derivatives and Their Application in Organic Synthesis
10.1021/cr010016n · 2003 · External reference
10.1002/9783527835652
10.1002/9783527835652 · 2024 · External reference
Strain-Release Amination
10.1126/science.aad6252 · 2016 · External reference
Carbopalladation of C–C σ-Bonds Enabled by Strained Boronate Complexes
10.1038/s41557-018-0181-x · 2019 · External reference
Radical Addition to Strained σ-Bonds Enables the Stereocontrolled Synthesis of Cyclobutyl Boronic Esters
10.1021/jacs.9b03653 · 2019 · External reference
Photochemical Strain-Release-Driven Cyclobutylation of C(sp3)-Centered Radicals
10.1002/anie.201908951 · 2020 · External reference
Polarity-Reversal Strategy for the Functionalization of Electrophilic Strained Molecules via Light-Driven Cobalt Catalysis
10.1021/jacs.0c00245 · 2020 · External reference
Oligosilanes as Silyl Radical Precursors through Oxidative Si-Si Bond Cleavage Using Redox Catalysis
10.1002/anie.202011738 · 2021 · External reference
C(sp2)–H Cyclobutylation of Hydroxyarenes Enabled by Silver-π-Acid Catalysis: Diastereocon-trolled Synthesis of 1,3-Difunctionalized Cyclobutanes
10.1039/d3sc03258b · 2023 · External reference
Lewis Acid-Catalyzed Diastereoselective Formal Ene Reaction of Thioindolinones/Thiolactams with Bicyclobutanes
10.1039/d4sc02194k · 2024 · External reference
Lewis Acid-Assisted Formal C═S Insertion of Thioindolinones to Bicyclobutanes: Diastereoselective Access to Trisubstituted Cyclobutanethiols
10.1021/acs.orglett.5c03564 · 2025 · External reference
Rh-catalyzed C–C bond cleavage by transfer hydroformylation
10.1126/science.1261232 · 2015 · External reference
Strain-Release Pudovik Reaction Enabled Diastereodivergent Hydroxy Transfer to Bicyclo[1.1.0]butanes Using Diphenyl Phosphine Oxide
10.1021/acscatal.6c00070 · 2026 · External reference
Escape from Flatland: Increasing Saturation as an Approach to Improving Clinical Success
10.1021/jm901241e · 2009 · External reference
The impact of aromatic ring count on compound developability-are too many aromatic rings a liability in drug design?
10.1016/j.drudis.2009.07.014 · 2009 · External reference
Escape from Flatland 2: complexity and promiscuity
10.1039/c2md20347b · 2013 · External reference
Saturated bioisosteres of benzene: where to go next?
10.1039/c8ob02812e · 2019 · External reference
Bioisosteres of the Phenyl Ring: Recent Strategic Applications in Lead Optimization and Drug Design
10.1021/acs.jmedchem.1c01215 · 2021 · External reference
Saturated Bioisosteres of ortho-Substituted Benzenes
10.1002/anie.202004183 · 2020 · External reference
1,2-Disubstituted bicyclo[2.1.1]hexanes as saturated bioisosteres of ortho-substituted benzene
10.1039/d3sc05121h · 2023 · External reference
Practical and Facile Access to Bicyclo[3.1.1]heptanes: Potent Bioisosteres of meta-Substituted Benzenes
10.1021/jacs.2c09733 · 2022 · External reference
Intermolecular [2π+2σ]- Photocycloaddition Enabled by Triplet Energy Transfer
10.1038/s41586-022-04636-x · 2022 · External reference
Strain-Release [2π + 2σ] Cycloadditions for the Synthesis of Bicyclo[2.1.1]hexanes Initiated by Energy Transfer
10.1021/jacs.2c02976 · 2022 · External reference
Beyond Bioisosteres: Divergent Synthesis of Azabicyclohexanes and Cyclobutenyl Amines from Bicyclobutanes
10.1002/anie.202204719 · 2022 · External reference
Catalytic Formal [2π+2σ] Cycloaddition of Aldehydes with Bicyclobutanes: Expedient Access to Polysubstituted 2-Oxabicyclo[2.1.1]hexanes
10.1002/anie.202305043 · 2023 · External reference
Lewis Acid Catalyzed Formal (3 + 2)-Cycloaddition of Bicyclo[1.1.0]butanes with Ketenes
10.1002/anie.202304771 · 2023 · External reference
Intermolecular Formal Cycloaddition of Indoles with Bicyclo[1.1.0]butanes by Lewis acid Catalysis
10.1002/anie.202308606 · 2023 · External reference
Silver-Catalyzed Dearomative [2π+2σ] Cycloadditions of Indoles with Bicyclobutanes: Access to Indoline Fused Bicyclo[2.1.1]hexanes
10.1002/anie.202310066 · 2023 · External reference
Synthesis of Polysubstituted 2-Oxabicyclo[2.1.1]Hexanes via Visible Light Induced Energy Transfer
10.1021/jacs.2c09248 · 2022 · External reference
Divergent Enantioselective Access to Diverse Chiral Compounds from Bicyclo[1.1.0]butanes and α,β-Unsaturated Ketones under Catalyst Control
10.1021/jacs.4c10153 · 2024 · External reference
Enantioselective [2π + 2σ] Photocycloaddition Enabled by Brønsted Acid Catalyzed Chromophore Activation
10.1021/jacs.4c13596 · 2024 · External reference
Lewis acid-catalyzed (3 + 2) annulation of bicyclobutanes with ynamides: access to 2-amino-bicyclo[2.1.1]hexenes
10.1039/d4sc03893b · 2024 · External reference
Lewis Acid Catalyzed Cycloaddition of Bicyclobutanes with Ynamides for the Synthesis of Polysubstituted 2-Amino-bicyclo[2.1.1]hexenes
10.1002/anie.202405781 · 2024 · External reference
Palladium-Catalyzed Ligand-Controlled Switchable Hetero-(5 + 3)/Enantioselective [2σ+2σ] Cycloadditions of Bicyclobutanes with Vinyl Oxiranes
10.1021/jacs.4c01851 · 2024 · External reference
Palladium-Catalyzed Double Strain-Release (3 + 3) Cycloaddition for the Synthesis of Vinylbicyclo[3.1.1]heptanes
10.1039/d5qo00460h · 2025 · External reference
Photochemical Intermolecular [3σ +2σ]-Cycloaddition for the Construction of Aminobicyclo[3.1.1]- heptanes
10.1021/jacs.2c11501 · 2022 · External reference
Selective [2σ+2σ] Cycloaddition Enabled by Boronyl Radical Catalysis: Synthesis of Highly Substituted Bicyclo[3.1.1]heptanes
10.1021/jacs.2c13740 · 2023 · External reference
Photocatalyzed [2σ + 2σ] and [2σ + 2π] Cycloadditions for the Synthesis of Bicyclo[3.1.1]heptanes and 5- or 6-Membered Carbocycles
10.1021/jacs.3c09789 · 2023 · External reference
Silver-Enabled Cycloaddition of Bicyclobutanes with Isocyanides for the Synthesis of Polysubstituted 3-Azabicyclo[3.1.1]heptanes
10.1002/anie.202402730 · 2024 · External reference
Synthesis of Azabicyclo[3.1.1]heptenes Enabled by Catalyst-Controlled Annulations of Bicyclo[1.1.0]butanes with Vinyl Azides
10.1021/jacs.4c04485 · 2024 · External reference
Catalytic Asymmetric Construction of Chiral Polysubstituted 3-Azabicyclo[3.1.1]heptanes by Copper-Catalyzed Stereoselective Formal [4π+2σ] Cycloaddition
10.1021/jacs.4c06436 · 2024 · External reference
Formal [2σ+2σ] Cycloaddition of Aziridines with Bicyclo[1.1.0]-butanes: Access to Enantiopure 2-Azabicyclo[3.1.1]-heptane Derivatives
10.1021/jacs.4c11296 · 2024 · External reference
Ring Expansion toward Fused Diazabicyclo[3.1.1]heptanes through Lewis Acid Catalyzed Highly Selective C-C/C-N Bond Cross-Exchange Reaction between Bicyclobutanes and Diaziridines
10.1002/anie.202416741 · 2025 · External reference
Eu(OTf)3-Catalyzed Formal Dipolar [4π+2σ] Cycloaddition of Bicyclo-[1.1.0]butanes with Nitrones: Access to Polysubstituted 2-Oxa-3-azabicyclo[3.1.1]heptanes
10.1002/anie.202318476 · 2024 · External reference
Enantioselective Formal (3+3) Cycloaddition of Bicyclobutanes with Nitrones Enabled by Asymmetric Lewis Acid Catalysis
10.1038/s41467-024-52419-x · 2024 · External reference
Copper-Catalyzed Enantioselective [4π + 2σ] Cycloaddition of Bicyclobutanes with Nitrones
10.1021/jacs.4c10123 · 2024 · External reference
Divergent Synthesis of Sulfur-Containing Bridged Cyclobutanes by Lewis Acid Catalyzed Formal Cycloadditions of Pyridinium 1,4-Zwitterionic Thiolates and Bicyclobutanes
10.1002/anie.202484061 · 2024 · External reference
Lewis-Acid-Catalyzed Dearomative [4π + 2σ] Cycloaddition of Bicyclobutanes with Isoquinolinium Methylides for the Synthesis of Ring-Fused Azabicyclo[3.1.1]heptanes
10.1021/acs.orglett.4c03489 · 2024 · External reference
Lewis Acid Catalyzed [4 + 2] Annulationof Bicyclobutanes with Dienol Ethers for the Synthesis of Bicyclo[4.1.1]octanes
10.1039/d4sc02767a · 2024 · External reference
Hexafluoroisopropanol as a highly versatile solvent
10.1038/s41570-017-0088 · 2017 · External reference
Fluorinated alcohols: magic reaction medium and promoters for organic synthesis
10.1002/tcr.201900020 · 2020 · External reference
HFIP-promoted formal [2π +2σ] cycloaddition of para-quinone methides with bicyclo[1.1.0]butanes: an approach towards spiro-bicyclo[2.1.1]hexanes
10.1039/d4qo02226b · 2025 · External reference
HFIP-Mediated (3+2) Annulation of Bicyclobutanes with Indolyl Alcohols for Diastereoselective Access to Tetracyclic Spiroindolenines
10.1021/acs.orglett.5c05244 · 2026 · External reference
HFIP-Mediated Ring Opening of Bicyclo[1.1.0]butanes with Hydroperoxides for Diastereoselective Access to Peroxycyclobutanes
10.1021/acs.orglett.5c03346 · 2025 · External reference
2H-Azirines as Synthetic Tools in Organic Chemistry
10.1002/1099-0690(200107)2001:13<2401::aid-ejoc2401>3.0.co;2-u · ExternalCitation · doi-reference
10.1002/9781118978429
10.1002/9781118978429 · ExternalCitation · doi-reference
10.1002/9783527835652
10.1002/9783527835652 · ExternalCitation · doi-reference
The Concept of Strain in Organic Chemistry
10.1002/anie.198603121 · ExternalCitation · doi-reference
Propellanes - from a chemical curiosity to “explosive” materials and natural products
10.1002/anie.201603951 · ExternalCitation · doi-reference
Photochemical Strain-Release-Driven Cyclobutylation of C(sp3)-Centered Radicals
10.1002/anie.201908951 · ExternalCitation · doi-reference
Saturated Bioisosteres of ortho-Substituted Benzenes
10.1002/anie.202004183 · ExternalCitation · doi-reference
Asymmetric Catalytic Reactions of Donor-Acceptor Cyclopropanes
10.1002/anie.202006736 · ExternalCitation · doi-reference
Oligosilanes as Silyl Radical Precursors through Oxidative Si-Si Bond Cleavage Using Redox Catalysis
10.1002/anie.202011738 · ExternalCitation · doi-reference
Beyond Bioisosteres: Divergent Synthesis of Azabicyclohexanes and Cyclobutenyl Amines from Bicyclobutanes
10.1002/anie.202204719 · ExternalCitation · doi-reference
Lewis Acid Catalyzed Formal (3 + 2)-Cycloaddition of Bicyclo[1.1.0]butanes with Ketenes
10.1002/anie.202304771 · ExternalCitation · doi-reference
Catalytic Formal [2π+2σ] Cycloaddition of Aldehydes with Bicyclobutanes: Expedient Access to Polysubstituted 2-Oxabicyclo[2.1.1]hexanes
10.1002/anie.202305043 · ExternalCitation · doi-reference
Intermolecular Formal Cycloaddition of Indoles with Bicyclo[1.1.0]butanes by Lewis acid Catalysis
10.1002/anie.202308606 · ExternalCitation · doi-reference
Silver-Catalyzed Dearomative [2π+2σ] Cycloadditions of Indoles with Bicyclobutanes: Access to Indoline Fused Bicyclo[2.1.1]hexanes
10.1002/anie.202310066 · ExternalCitation · doi-reference
Eu(OTf)3-Catalyzed Formal Dipolar [4π+2σ] Cycloaddition of Bicyclo-[1.1.0]butanes with Nitrones: Access to Polysubstituted 2-Oxa-3-azabicyclo[3.1.1]heptanes
10.1002/anie.202318476 · ExternalCitation · doi-reference
Silver-Enabled Cycloaddition of Bicyclobutanes with Isocyanides for the Synthesis of Polysubstituted 3-Azabicyclo[3.1.1]heptanes
10.1002/anie.202402730 · ExternalCitation · doi-reference
Lewis Acid Catalyzed Cycloaddition of Bicyclobutanes with Ynamides for the Synthesis of Polysubstituted 2-Amino-bicyclo[2.1.1]hexenes
10.1002/anie.202405781 · ExternalCitation · doi-reference
Lewis Acid-Catalyzed Unusual (4 + 3) Annulation of para-Quinone Methides with Bicyclobutanes: Access to Oxabicyclo[4.1.1]octanes
10.1002/anie.202408610 · ExternalCitation · doi-reference
Ring Expansion toward Fused Diazabicyclo[3.1.1]heptanes through Lewis Acid Catalyzed Highly Selective C-C/C-N Bond Cross-Exchange Reaction between Bicyclobutanes and Diaziridines
10.1002/anie.202416741 · ExternalCitation · doi-reference
Divergent Synthesis of Sulfur-Containing Bridged Cyclobutanes by Lewis Acid Catalyzed Formal Cycloadditions of Pyridinium 1,4-Zwitterionic Thiolates and Bicyclobutanes
10.1002/anie.202484061 · ExternalCitation · doi-reference
Simultaneous Activation of Bicyclobutanes and Indolyl Alcohols with HFIP: Access to Indole-Fused Bicyclo[3.1.1]Heptanes
10.1002/anie.202501655 · ExternalCitation · doi-reference
Ueber Polyacetylenverbindungen
10.1002/cber.18850180296 · ExternalCitation · doi-reference
2H-Azirines: Recent Progress in Synthesis and Applications
10.1002/ejoc.202301292 · ExternalCitation · doi-reference
Donor-Acceptor Cyclopropanes in the Synthesis of Carbocycles
10.1002/tcr.201800166 · ExternalCitation · doi-reference
Fluorinated alcohols: magic reaction medium and promoters for organic synthesis
10.1002/tcr.201900020 · ExternalCitation · doi-reference
The impact of aromatic ring count on compound developability-are too many aromatic rings a liability in drug design?
10.1016/j.drudis.2009.07.014 · ExternalCitation · doi-reference
Strain-release transformations of bicyclo[1.1.0]butanes and [1.1.1]propellanes
10.1016/j.tchem.2024.100070 · ExternalCitation · doi-reference
Recent advances in 2H-azirine chemistry
10.1016/j.tet.2013.02.020 · ExternalCitation · doi-reference
Recent developments in the synthesis and reactivity of methylene- and alkylidenecyclopropane derivatives
10.1016/j.tet.2014.04.057 · ExternalCitation · doi-reference
Exploiting Heavier Organochalcogen Compounds in Donor-Acceptor Cyclopropane Chemistry
10.1021/acs.accounts.1c00023 · ExternalCitation · doi-reference
Employing Arynes in Diels-Alder Reactions and Transition-Metal-Free Multicomponent Coupling and Arylation Reactions
10.1021/acs.accounts.6b00188 · ExternalCitation · doi-reference
Catalytic Enantioselective Ring-Opening Reactions of Cyclopropanes
10.1021/acs.chemrev.0c00109 · ExternalCitation · doi-reference
C–C Bond Cleavages of Cyclopropenes: Operating for Selective Ring-Opening Reactions
10.1021/acs.chemrev.0c00151 · ExternalCitation · doi-reference
Bioisosteres of the Phenyl Ring: Recent Strategic Applications in Lead Optimization and Drug Design
10.1021/acs.jmedchem.1c01215 · ExternalCitation · doi-reference
Building the Housane: Diastereoselective Synthesis and Characterization of Bicyclo[2.1.0]pentane Carboxylic Acids
10.1021/acs.joc.9b03044 · ExternalCitation · doi-reference
Lewis-Acid-Catalyzed Dearomative [4π + 2σ] Cycloaddition of Bicyclobutanes with Isoquinolinium Methylides for the Synthesis of Ring-Fused Azabicyclo[3.1.1]heptanes
10.1021/acs.orglett.4c03489 · ExternalCitation · doi-reference
Palladium-Catalyzed Strain-Enabled [2π + 2σ] Cycloadditions of Vinyl Bicyclo[1.1.0]Butanes with Methyleneindolinones
10.1021/acs.orglett.4c04224 · ExternalCitation · doi-reference
Structure-Dependent, Switchable Alder-Ene/[2π + 2σ] Cycloadditions of Vinyl Bicyclo[1.1.0]Butanes with α-Ketoesters Enabled by Palladium Catalysis
10.1021/acs.orglett.4c04251 · ExternalCitation · doi-reference
HFIP-Mediated Spiro-annulation of Bicyclo[1.1.0]butanes with α-Halo Hydroxamates: Access to Functionalized Spirocyclobutenes
10.1021/acs.orglett.5c02493 · ExternalCitation · doi-reference
HFIP-Mediated Ring Opening of Bicyclo[1.1.0]butanes with Hydroperoxides for Diastereoselective Access to Peroxycyclobutanes
10.1021/acs.orglett.5c03346 · ExternalCitation · doi-reference
Lewis Acid-Assisted Formal C═S Insertion of Thioindolinones to Bicyclobutanes: Diastereoselective Access to Trisubstituted Cyclobutanethiols
10.1021/acs.orglett.5c03564 · ExternalCitation · doi-reference
HFIP-Mediated (3+2) Annulation of Bicyclobutanes with Indolyl Alcohols for Diastereoselective Access to Tetracyclic Spiroindolenines
10.1021/acs.orglett.5c05244 · ExternalCitation · doi-reference
Recent Advances in Catalytic Asymmetric Transformations of Bicyclobutane: A Versatile Building Block for Enantiopure Bioisosteric Molecules
10.1021/acscatal.5c01900 · ExternalCitation · doi-reference
Strain-Release Pudovik Reaction Enabled Diastereodivergent Hydroxy Transfer to Bicyclo[1.1.0]butanes Using Diphenyl Phosphine Oxide
10.1021/acscatal.6c00070 · ExternalCitation · doi-reference
Nuclear Magnetic Resonance Spectra in Liquid Crystals and Molecular Structure
10.1021/ar50039a001 · ExternalCitation · doi-reference
Ring-Strain-Enabled Reaction Discovery: New Heterocycles from Bicyclo[1.1.0]butanes
10.1021/ar500437h · ExternalCitation · doi-reference
Electrophilic Cyclopropanes in Organic Synthesis
10.1021/ar50134a004 · ExternalCitation · doi-reference
Use of cyclopropanes and their derivatives in organic synthesis
10.1021/cr00091a005 · ExternalCitation · doi-reference
Small Ring Propellanes
10.1021/cr00095a001 · ExternalCitation · doi-reference
Donor-Acceptor-Substituted Cyclopropane Derivatives and Their Application in Organic Synthesis
10.1021/cr010016n · ExternalCitation · doi-reference
X-ray and theoretical analysis of the relationship between substituent steric effects and the structure of bicyclo[1.1.0]butane. The unexpected flexibility of the bicyclo[1.1.0]butane skeleton
10.1021/ja00356a025 · ExternalCitation · doi-reference
Evaluation of Strain in Hydrocarbons. The Strain in Adamantane and its Origin
10.1021/ja00711a030 · ExternalCitation · doi-reference
The Electronic Structure and Reactivity of Small Ring Compounds. I. Bicyclobutane
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