Research graph
References from Discovery of Pyrimidinedione Derivatives Containing Oxime Ester/Carbamate Fragments as Potent Protoporphyrinogen IX Oxidase Inhibitors. Local targets link to admitted publications; unresolved targets remain external evidence.
Characterization of hemY-type protoporphyrinogen IX oxidase genes from cyanobacteria and their functioning in transgenic Arabidopsis
10.1007/s11103-019-00925-8 · 2019 · External reference
A codon deletion confers resistance to herbicides inhibiting protoporphyrinogen oxidase
10.1073/pnas.0603137103 · 2006 · External reference
Mechanistic insights into the substrate recognition of PPO: Toward the rational design of effective inhibitors
10.4155/fmc.14.29 · 2014 · External reference
Molecular simulations bring new insights into protoporphyrinogen IX oxidase/protoporphyrinogen IX interaction modes
10.1002/minf.201600008 · 2016 · External reference
Crystal structure of protoporphyrinogen IX oxidase: A key enzyme in haem and chlorophyll biosynthesis
10.1038/sj.emboj.7600189 · 2004 · External reference
The function of PROTOPORPHYRINOGEN IX OXIDASE in chlorophyll biosynthesis requires oxidised plastoquinone in Chlamydomonas reinhardtii
10.1038/s42003-019-0395-5 · 2019 · External reference
Design, synthesis, and biological activity evaluation of novel phenoxypyridine derivatives containing acylthiourea fragments as protoporphyrinogen oxidase inhibitor herbicides
10.1021/acs.jafc.4c09757 · 2025 · External reference
Design, synthesis, and herbicidal activity of novel diphenyl ether derivatives containing fast degrading tetrahydrophthalimide
10.1021/acs.jafc.0c00947 · 2020 · External reference
Synthesis, herbicidal activity, and QSAR of novel N-benzothiazolylpyrimidine-2,4-diones as protoporphyrinogen oxidase inhibitors
10.1021/acs.jafc.5b05378 · 2016 · External reference
Quantitative structural insight into human variegate porphyria disease
10.1074/jbc.m113.459768 · 2013 · External reference
Where do the electrons go? How numerous redox processes drive phytochemical diversity
10.1007/s11101-020-09738-w · 2021 · External reference
Design, synthesis, and biological activity determination of novel phenylpyrazole protoporphyrinogen oxidase inhibitor herbicides containing five-membered heterocycles
10.1021/acs.jafc.3c03108 · 2023 · External reference
Understanding the effects of ligand configuration on protoporphyrinogen IX oxidase with rationally designed 3-(N-phenyluracil)but-2-enoates
10.1021/acs.jafc.3c08483 · 2024 · External reference
Design, synthesis, and metabolism studies of N-1,4-diketophenyltriazinones as protoporphyrinogen IX oxidase Inhibitors
10.1021/acs.jafc.2c09082 · 2023 · External reference
Discovery of a potent thieno [2,3-d]pyrimidine-2,4-dione-Based protoporphyrinogen IX oxidase Inhibitor through an in silico structure-guided optimization approach
10.1021/acs.jafc.1c05665 · 2021 · External reference
Design and synthesis of acrylate and acrylamide substituted pyrimidinediones as potential PPO herbicides
10.1016/j.bmc.2020.115959 · 2021 · External reference
Absorption, distribution, metabolism, and excretion of a new herbicide, epyrifenacil, in rats
10.1021/acs.jafc.1c04167 · 2021 · External reference
Epyrifenacil, a new systemic PPO-inhibiting herbicide for broad-spectrum weed control
10.1002/ps.8244 · 2025 · External reference
Unresolved reference
External reference
Discovery of novel N-phenyltriazinone derivatives containing oxime ether or oxime ester moieties as promising protoporphyrinogen IX oxidase inhibitors
10.1021/acs.jafc.4c00272 · 2024 · External reference
Novel N-phenyltriazinone derivatives containing carbamate/oxime ester fragments as promising protoporphyrinogen IX oxidase inhibitors
10.1021/acs.jafc.5c16049 · 2026 · External reference
Novel N-phenyltriazinone derivatives containing oxazine/oxime fragments as promising protoporphyrinogen IX oxidase inhibitors
10.1021/acs.jafc.5c00979 · 2025 · External reference
Design, synthesis and herbicidal evaluation of novel uracil derivatives containing an isoxazoline moiety
10.1002/ps.5970 · 2020 · External reference
Novel phenylpyrazole derivatives containing carbonic ester moieties as protoporphyrinogen IX oxidase inhibitors
10.1021/acs.jafc.5c02008 · 2025 · External reference
Discovery of N-phenylaminomethylthioacetylpyrimidine-2,4-diones as protoporphyrinogen IX oxidase inhibitors through a reaction intermediate derivation approach
10.1021/acs.jafc.1c00796 · 2021 · External reference
Synthesis and biological activity evaluation of benzoxazinone-pyrimidinedione hybrids as potent protoporphyrinogen IX oxidase inhibitor
10.1021/acs.jafc.3c03593 · 2023 · External reference
Design, herbicidal activity, and QSAR analysis of cycloalka[d]quinazoline-2,4-dione-benzoxazinones as protoporphyrinogen IX oxidase inhibitors
10.1021/acs.jafc.9b02996 · 2019 · External reference
Synthesis and herbicidal activity of pyrido[2,3-d]pyrimidine-2,4-dione-benzoxazinone hybrids as protoporphyrinogen oxidase inhibitors
10.1021/acs.jafc.7b01990 · 2017 · External reference
Design and synthesis of novel pyrimidinedione derivatives containing dithioacetal structures as safer protoporphyrinogen IX oxidase inhibitors
10.1021/acs.jafc.5c17991 · 2026 · External reference
Design, synthesis and biological evaluation of N-phenylphthalimide protoporphyrinogen IX oxidase inhibitor herbicides
10.1021/acs.jafc.5c14456 · 2026 · External reference
Discovery of novel pyrazole derivatives with improved crop safety as 4-hydroxyphenylpyruvate dioxygenase-targeted herbicides
10.1021/acs.jafc.2c07551 · 2023 · External reference
Synthesis, herbicidal activity, and molecular mode of action evaluation of novel aryloxyphenoxypropionate/amide derivatives containing a quinazolinone moiety
10.1021/acs.jafc.3c08097 · 2024 · External reference
A deep eutectic solvent-based nanodelivery system for enhanced rice blast treatment
10.1021/acsnano.5c07377 · 2025 · External reference
Enriching screening libraries with bioactive fragment space
10.1016/j.bmcl.2016.06.013 · 2016 · External reference
Molecular dynamics simulations of biomolecules
10.1038/nsb0902-646 · 2002 · External reference
Molecular dynamics: Survey of methods for simulating the activity of proteins
10.1021/cr040426m · 2006 · External reference
Molecular insights into the mechanism of 4-hydroxyphenylpyruvate dioxygenase inhibition: Enzyme kinetics, X-ray crystallography and computational simulations
10.1111/febs.14747 · 2019 · External reference
LARMD: Integration of bioinformatic resources to profile ligand-driven protein dynamics with a case on the activation of estrogen receptor
10.1093/bib/bbz141 · 2020 · External reference
Rational redesign of enzyme via the combination of quantum mechanics/molecular mechanics, molecular dynamics, and structural biology study
10.1021/jacs.1c06227 · 2021 · External reference
Molecular simulations bring new insights into protoporphyrinogen IX oxidase/protoporphyrinogen IX interaction modes
10.1002/minf.201600008 · ExternalCitation · doi-reference
Design, synthesis and herbicidal evaluation of novel uracil derivatives containing an isoxazoline moiety
10.1002/ps.5970 · ExternalCitation · doi-reference
Epyrifenacil, a new systemic PPO-inhibiting herbicide for broad-spectrum weed control
10.1002/ps.8244 · ExternalCitation · doi-reference
Where do the electrons go? How numerous redox processes drive phytochemical diversity
10.1007/s11101-020-09738-w · ExternalCitation · doi-reference
Characterization of hemY-type protoporphyrinogen IX oxidase genes from cyanobacteria and their functioning in transgenic Arabidopsis
10.1007/s11103-019-00925-8 · ExternalCitation · doi-reference
Design and synthesis of acrylate and acrylamide substituted pyrimidinediones as potential PPO herbicides
10.1016/j.bmc.2020.115959 · ExternalCitation · doi-reference
Enriching screening libraries with bioactive fragment space
10.1016/j.bmcl.2016.06.013 · ExternalCitation · doi-reference
Design, synthesis, and herbicidal activity of novel diphenyl ether derivatives containing fast degrading tetrahydrophthalimide
10.1021/acs.jafc.0c00947 · ExternalCitation · doi-reference
Discovery of N-phenylaminomethylthioacetylpyrimidine-2,4-diones as protoporphyrinogen IX oxidase inhibitors through a reaction intermediate derivation approach
10.1021/acs.jafc.1c00796 · ExternalCitation · doi-reference
Absorption, distribution, metabolism, and excretion of a new herbicide, epyrifenacil, in rats
10.1021/acs.jafc.1c04167 · ExternalCitation · doi-reference
Discovery of a potent thieno [2,3-d]pyrimidine-2,4-dione-Based protoporphyrinogen IX oxidase Inhibitor through an in silico structure-guided optimization approach
10.1021/acs.jafc.1c05665 · ExternalCitation · doi-reference
Discovery of novel pyrazole derivatives with improved crop safety as 4-hydroxyphenylpyruvate dioxygenase-targeted herbicides
10.1021/acs.jafc.2c07551 · ExternalCitation · doi-reference
Design, synthesis, and metabolism studies of N-1,4-diketophenyltriazinones as protoporphyrinogen IX oxidase Inhibitors
10.1021/acs.jafc.2c09082 · ExternalCitation · doi-reference
Design, synthesis, and biological activity determination of novel phenylpyrazole protoporphyrinogen oxidase inhibitor herbicides containing five-membered heterocycles
10.1021/acs.jafc.3c03108 · ExternalCitation · doi-reference
Synthesis and biological activity evaluation of benzoxazinone-pyrimidinedione hybrids as potent protoporphyrinogen IX oxidase inhibitor
10.1021/acs.jafc.3c03593 · ExternalCitation · doi-reference
Synthesis, herbicidal activity, and molecular mode of action evaluation of novel aryloxyphenoxypropionate/amide derivatives containing a quinazolinone moiety
10.1021/acs.jafc.3c08097 · ExternalCitation · doi-reference
Understanding the effects of ligand configuration on protoporphyrinogen IX oxidase with rationally designed 3-(N-phenyluracil)but-2-enoates
10.1021/acs.jafc.3c08483 · ExternalCitation · doi-reference
Discovery of novel N-phenyltriazinone derivatives containing oxime ether or oxime ester moieties as promising protoporphyrinogen IX oxidase inhibitors
10.1021/acs.jafc.4c00272 · ExternalCitation · doi-reference
Design, synthesis, and biological activity evaluation of novel phenoxypyridine derivatives containing acylthiourea fragments as protoporphyrinogen oxidase inhibitor herbicides
10.1021/acs.jafc.4c09757 · ExternalCitation · doi-reference
Synthesis, herbicidal activity, and QSAR of novel N-benzothiazolylpyrimidine-2,4-diones as protoporphyrinogen oxidase inhibitors
10.1021/acs.jafc.5b05378 · ExternalCitation · doi-reference
Novel N-phenyltriazinone derivatives containing oxazine/oxime fragments as promising protoporphyrinogen IX oxidase inhibitors
10.1021/acs.jafc.5c00979 · ExternalCitation · doi-reference
Novel phenylpyrazole derivatives containing carbonic ester moieties as protoporphyrinogen IX oxidase inhibitors
10.1021/acs.jafc.5c02008 · ExternalCitation · doi-reference
Design, synthesis and biological evaluation of N-phenylphthalimide protoporphyrinogen IX oxidase inhibitor herbicides
10.1021/acs.jafc.5c14456 · ExternalCitation · doi-reference
Novel N-phenyltriazinone derivatives containing carbamate/oxime ester fragments as promising protoporphyrinogen IX oxidase inhibitors
10.1021/acs.jafc.5c16049 · ExternalCitation · doi-reference
Design and synthesis of novel pyrimidinedione derivatives containing dithioacetal structures as safer protoporphyrinogen IX oxidase inhibitors
10.1021/acs.jafc.5c17991 · ExternalCitation · doi-reference
Synthesis and herbicidal activity of pyrido[2,3-d]pyrimidine-2,4-dione-benzoxazinone hybrids as protoporphyrinogen oxidase inhibitors
10.1021/acs.jafc.7b01990 · ExternalCitation · doi-reference
Design, herbicidal activity, and QSAR analysis of cycloalka[d]quinazoline-2,4-dione-benzoxazinones as protoporphyrinogen IX oxidase inhibitors
10.1021/acs.jafc.9b02996 · ExternalCitation · doi-reference
A deep eutectic solvent-based nanodelivery system for enhanced rice blast treatment
10.1021/acsnano.5c07377 · ExternalCitation · doi-reference
Molecular dynamics: Survey of methods for simulating the activity of proteins
10.1021/cr040426m · ExternalCitation · doi-reference
Rational redesign of enzyme via the combination of quantum mechanics/molecular mechanics, molecular dynamics, and structural biology study
10.1021/jacs.1c06227 · ExternalCitation · doi-reference
Molecular dynamics simulations of biomolecules
10.1038/nsb0902-646 · ExternalCitation · doi-reference
The function of PROTOPORPHYRINOGEN IX OXIDASE in chlorophyll biosynthesis requires oxidised plastoquinone in Chlamydomonas reinhardtii
10.1038/s42003-019-0395-5 · ExternalCitation · doi-reference
Crystal structure of protoporphyrinogen IX oxidase: A key enzyme in haem and chlorophyll biosynthesis
10.1038/sj.emboj.7600189 · ExternalCitation · doi-reference
A codon deletion confers resistance to herbicides inhibiting protoporphyrinogen oxidase
10.1073/pnas.0603137103 · ExternalCitation · doi-reference
Quantitative structural insight into human variegate porphyria disease
10.1074/jbc.m113.459768 · ExternalCitation · doi-reference
LARMD: Integration of bioinformatic resources to profile ligand-driven protein dynamics with a case on the activation of estrogen receptor
10.1093/bib/bbz141 · ExternalCitation · doi-reference
Molecular insights into the mechanism of 4-hydroxyphenylpyruvate dioxygenase inhibition: Enzyme kinetics, X-ray crystallography and computational simulations
10.1111/febs.14747 · ExternalCitation · doi-reference
Mechanistic insights into the substrate recognition of PPO: Toward the rational design of effective inhibitors
10.4155/fmc.14.29 · ExternalCitation · doi-reference
