Research graph
References from Mechanisms and Application Prospects of Nicotine from Plant Defense to the Frontiers of Bioengineering. Local targets link to admitted publications; unresolved targets remain external evidence.
Tobacco and Nicotine Use
10.1038/s41572-022-00346-w · 2022 · External reference
Enantiomeric Composition of Nicotine in Smokeless Tobacco, Medicinal Products, and Commercial Reagents
10.1002/(sici)1520-636x(1998)10:73.0.co;2-# · 1998 · External reference
Advances in Regulatory Mechanism(s) and Biotechnological Approaches to Modulate Nicotine Content in Tobacco
10.1016/j.plaphy.2024.108397 · 2024 · External reference
Wild Tobacco Genomes Reveal the Evolution of Nicotine Biosynthesis
10.1073/pnas.1700073114 · 2017 · External reference
Complete Biosynthesis of Nicotine
10.1016/j.cell.2026.03.034 · 2026 · External reference
Bacterial Catabolism of Nicotine: Catabolic Strains, Pathways and Modules
10.1016/j.envres.2020.109258 · 2020 · External reference
Tobacco Nicotine Uptake Permease Regulates the Expression of a Key Transcription Factor Gene in the Nicotine Biosynthesis Pathway
10.1104/pp.114.251645 · 2014 · External reference
Recruitment of a Duplicated Primary Metabolism Gene into the Nicotine Biosynthesis Regulon in Tobacco
10.1111/j.1365-313x.2011.04647.x · 2011 · External reference
A PIP-Family Protein Is Required for Biosynthesis of Tobacco Alkaloids
10.1007/s11103-008-9424-3 · 2009 · External reference
Nicotinic Acetylcholine Receptor Modulator Insecticides Act on Diverse Receptor Subtypes with Distinct Subunit Compositions
10.1371/journal.pgen.1009920 · 2022 · External reference
Nicotine Rebalances NAD+ Homeostasis and Improves Aging-Related Symptoms in Male Mice by Enhancing NAMPT Activity
10.1038/s41467-023-36543-8 · 2023 · External reference
The Defensive Chemistry of Ants
10.1007/978-3-7091-6341-2_2 · 2000 · External reference
Trail-Following Behaviour in Two Aphaenogaster Ants
10.1007/s00049-011-0071-9 · 2011 · External reference
Dufour’s Gland and Poison Gland Chemistry of the Myrmicine Ant,Messor Capensis (Mayr)
10.1007/bf00984878 · 1993 · External reference
Nicotine Synthesis in Nicotiana Tabacum L. Induced by Mechanical Wounding Is Regulated by Auxin
10.1093/jxb/erl051 · 2006 · External reference
Transcriptomic Analysis Provides Insights into the AUXIN RESPONSE FACTOR 6-Mediated Repression of Nicotine Biosynthesis in Tobacco (Nicotiana tabacum L.)
10.1007/s11103-021-01175-3 · 2021 · External reference
Differential Induction by Methyl Jasmonate of Genes Encoding Ornithine Decarboxylase and Other Enzymes Involved in Nicotine Biosynthesis in Tobacco Cell Cultures
10.1023/a:1006058700949 · 1998 · External reference
Gene Expression in Tobacco Low-Nicotine Mutants
10.1105/tpc.6.5.723 · 1994 · External reference
Generation of Tobacco Lines with Widely Different Reduction in Nicotine Levels via RNA Silencing Approaches
10.1007/s12038-008-0035-6 · 2008 · External reference
Silencing of PMT Expression Caused a Surge of Anatabine Accumulation in Tobacco
10.1007/s11033-009-9446-1 · 2009 · External reference
Cloning and Characterization of a Nicotiana tabacum Methylputrescine Oxidase Transcript
10.1016/j.phytochem.2006.11.003 · 2007 · External reference
Molecular Cloning of N-Methylputrescine Oxidase from Tobacco
10.1093/pcp/pcm018 · 2007 · External reference
Genetic Attenuation of Alkaloids and Nicotine Content in Tobacco (Nicotiana tabacum)
10.1007/s00425-020-03387-1 · 2020 · External reference
Molecular Characterization of Quinolinate Phosphoribosyltransferase (QPRtase) in Nicotiana
10.1023/a:1026590521318 · 2000 · External reference
Early Steps in the Biosynthesis of NAD in Arabidopsis Start with Aspartate and Occur in the Plastid
10.1104/pp.106.081091 · 2006 · External reference
Cloning and Functional Characterization of Quinolinic Acid Phosphoribosyl Transferase (QPT) Gene of Nicotiana tabacum
10.1111/ppl.12559 · 2017 · External reference
The A622 Gene in Nicotiana glauca (Tree Tobacco): Evidence for a Functional Role in Pyridine Alkaloid Synthesis
10.1007/s11103-008-9425-2 · 2009 · External reference
Genomic Insights into the Evolution of the Nicotine Biosynthesis Pathway in Tobacco
10.1104/pp.17.00070 · 2017 · External reference
Transgenic and Mutation-Based Suppression of a Berberine Bridge Enzyme-like (BBL) Gene Family Reduces Alkaloid Content in Field-Grown Tobacco
10.1371/journal.pone.0117273 · 2015 · External reference
Vacuole-Localized Berberine Bridge Enzyme-like Proteins Are Required for a Late Step of Nicotine Biosynthesis in Tobacco
10.1104/pp.110.170878 · 2011 · External reference
Nicotine Biosynthesis Is Completed by Cryptic Activating Glucosylation
10.1038/s41467-026-72705-0 · 2026 · External reference
Vacuolar Transport of Nicotine Is Mediated by a Multidrug and Toxic Compound Extrusion (MATE) Transporter in Nicotiana Tabacum
10.1073/pnas.0812512106 · 2009 · External reference
Involvement of the Leaf-Specific Multidrug and Toxic Compound Extrusion (MATE) Transporter Nt-JAT2 in Vacuolar Sequestration of Nicotine in Nicotiana Tabacum
10.1371/journal.pone.0108789 · 2014 · External reference
Multidrug and Toxic Compound Extrusion-Type Transporters Implicated in Vacuolar Sequestration of Nicotine in Tobacco Roots
10.1104/pp.108.132811 · 2009 · External reference
Crystal Structures of a Nicotine MATE Transporter Provide Insight into Its Mechanism of Substrate Transport
10.1002/1873-3468.14136 · 2021 · External reference
Tobacco Nicotine Uptake Permease (NUP1) Affects Alkaloid Metabolism
10.1073/pnas.1108620108 · 2011 · External reference
Root-to-Shoot Translocation of Alkaloids Is Dominantly Suppressed in Nicotiana Alata
10.1093/pcp/pcs065 · 2012 · External reference
Alteration of the Alkaloid Profile in Genetically Modified Tobacco Reveals a Role of Methylenetetrahydrofolate Reductase in Nicotine N -Demethylation
10.1104/pp.112.209247 · 2013 · External reference
Low H3K27me3 Deposition at CYP82E4 Determines the Nicotinic Conversion Rate in Nicotiana Tabacum
10.1016/j.plaphy.2023.108234 · 2024 · External reference
BBL Enzymes Exhibit Enantiospecific Preferences in the Biosynthesis of Pyridine Alkaloids in Nicotiana Tabacum L
10.1016/j.phytochem.2024.114363 · 2025 · External reference
An Improved Nicotiana Benthamiana Bioproduction Chassis Provides Novel Insights into Nicotine Biosynthesis
10.1111/nph.19141 · 2023 · External reference
Jasmonates: News on Occurrence, Biosynthesis, Metabolism and Action of an Ancient Group of Signaling Compounds
10.3390/ijms19092539 · 2018 · External reference
Master MYCs: MYC2, the Jasmonate Signaling “Master Switch
10.1105/tpc.19.00004 · 2019 · External reference
Effects of Overexpression of Jasmonic Acid Biosynthesis Genes on Nicotine Accumulation in Tobacco
10.1002/pld3.36 · 2018 · External reference
The Multifaceted Roles of MYC2 in Plants: Toward Transcriptional Reprogramming and Stress Tolerance by Jasmonate Signaling
10.3389/fpls.2022.868874 · 2022 · External reference
Tobacco MYC2 Regulates Jasmonate-Inducible Nicotine Biosynthesis Genes Directly and by Way of the NIC2-Locus ERF Genes
10.1093/pcp/pcr063 · 2011 · External reference
Clustered Transcription Factor Genes Regulate Nicotine Biosynthesis in Tobacco
10.1105/tpc.110.078543 · 2010 · External reference
Auxin-Induced Nicotine Inhibition Is Mediated by NaARF5 Through the Suppression of NaERF1-Like Expression and Interaction With NaERF1-Like in Nicotiana Attenuata
10.1111/pbi.70524 · 2026 · External reference
Natural and Induced Variations in Transcriptional Regulator Genes Result in Low-Nicotine Phenotypes in Tobacco
10.1111/tpj.15923 · 2022 · External reference
Exploration of Jasmonate Signalling via Automated and Standardized Transient Expression Assays in Tobacco Cells
10.1111/j.1365-313x.2005.02586.x · 2005 · External reference
Strigolactone Signaling Regulates Specialized Metabolism in Tobacco Stems and Interactions with Stem-Feeding Herbivores
10.1371/journal.pbio.3000830 · 2020 · External reference
Genetic Manipulation of Transcriptional Regulators Alters Nicotine Biosynthesis in Tobacco
10.1093/pcp/pcaa036 · 2020 · External reference
Mutation in Shoot-to-Root Mobile Transcription Factor, Elongated Hypocotyl 5, Leads to Low Nicotine Levels in Tobacco
10.1016/j.jhazmat.2023.133255 · 2024 · External reference
ABA-INSENSITIVE 4 Promotes Nicotine Biosynthesis under High Light in Nicotiana Attenuata
10.1016/j.plantsci.2025.112416 · 2025 · External reference
ZEITLUPE in the Roots of Wild Tobacco Regulates Jasmonate-Mediated Nicotine Biosynthesis and Resistance to a Generalist Herbivore
10.1104/pp.18.00315 · 2018 · External reference
microRNAs and Their Roles in Plant Development
10.3389/fpls.2022.824240 · 2022 · External reference
The Roles of Plant MicroRNAs in Defence Against Pathogens
10.1111/mpp.70189 · 2026 · External reference
Contemporary Understanding of miRNA-Based Regulation of Secondary Metabolites Biosynthesis in Plants
10.3389/fpls.2017.00374 · 2017 · External reference
Regulation of Nicotine Biosynthesis by an Endogenous Target Mimicry of MicroRNA in Tobacco
10.1104/pp.15.00649 · 2015 · External reference
Transcriptome Analysis Reveals Key Genes Involved in the Regulation of Nicotine Biosynthesis at Early Time Points after Topping in Tobacco (Nicotiana tabacum L.)
10.1186/s12870-020-2241-9 · 2020 · External reference
Transcriptional Activation of NaNAC72 Suppresses Nicotine Biosynthesis in DNA Methyltransferase NaDRM2-Like2Mutants of Nicotiana attenuata
10.1111/pbi.70425 · 2026 · External reference
Biological Traits, Detoxification Enzyme Activity, and Transcriptomic Profiles of the Fall Armyworm in Response to Nicotine
10.1093/jee/toaf270 · 2025 · External reference
Studies on the Mode of Action of Neurotoxic Insecticides
10.1584/jpestics.j16-01 · 2016 · External reference
The Role of the Bemisia Tabaci and Trialeurodes Vaporariorum Cytochrome-P450 Clade CYP6DPx in Resistance to Nicotine and Neonicotinoids
10.1016/j.pestbp.2023.105743 · 2024 · External reference
Differences in Nicotine Metabolism of Two Nicotiana Attenuata Herbivores Render Them Differentially Susceptible to a Common Native Predator
10.1371/journal.pone.0095982 · 2014 · External reference
An in Silico Pipeline for Enzyme-Substrate Modelling Using Arthropod P450s
10.1016/j.pestbp.2025.106816 · 2026 · External reference
Acylsugars, Nicotine and a Protease Inhibitor Provide Variable Protection for Nicotiana Benthamiana in a Natural Setting
10.1111/pce.15195 · 2025 · External reference
Research Progress on Antibacterial Activities and Mechanisms of Natural Alkaloids: A Review
10.3390/antibiotics10030318 · 2021 · External reference
Salicylic Acid-Producing Endophytic Bacteria Increase Nicotine Accumulation and Resistance against Wildfire Disease in Tobacco Plants
10.3390/microorganisms8010031 · 2020 · External reference
DIfferential Response Of Maize And Mungbean To Tobacco Allelopathy
10.1017/s0014479714000106 · 2014 · External reference
Biochar-Mediated Changes in Soil Quality and Plant Growth in a Three Year Field Trial
10.1016/j.soilbio.2011.10.012 · 2012 · External reference
Antimicrobial Mechanisms and Clinical Application Prospects of Antimicrobial Peptides
10.3390/molecules27092675 · 2022 · External reference
Mechanisms of Action of Antimicrobials: Focus on Fluoroquinolones
10.1086/319370 · 2001 · External reference
A Quinoline Alkaloid Potentially Modulates the Amyloidogenic Structural Transitions of the Biofilm Scaffolding Small Basic Protein
10.1080/07391102.2021.2020165 · 2023 · External reference
A Bowman-Birk Inhibitor from the Seeds of Luetzelburgia Auriculata Inhibits Staphylococcus Aureus Growth by Promoting Severe Cell Membrane Damage
10.1021/acs.jnatprod.7b00545 · 2018 · External reference
Multimodal Interactions of Drugs, Natural Compounds and Pollutants with the Gut Microbiota
10.1038/s41579-022-00681-5 · 2022 · External reference
High Temperature Induces Expression of Tobacco Transcription Factor NtMYC2a to Regulate Nicotine and JA Biosynthesis
10.3389/fphys.2016.00465 · 2016 · External reference
Jasmonate Mediates Salt-Induced Nicotine Biosynthesis in Tobacco (Nicotiana tabacum L.)
10.1016/j.pld.2016.06.001 · 2016 · External reference
Gamma-Aminobutyric Acid Mediates Nicotine Biosynthesis in Tobacco under Flooding Stress
10.1016/j.pld.2016.05.004 · 2016 · External reference
Morphophysiological Reconfiguration and Antioxidant Networking Underpin Selenium-Mediated Drought Adaptation in Nicotiana Tabacum
10.1021/acsomega.5c02028 · 2025 · External reference
Knockout of a Key Gene of the Nicotine Biosynthetic Pathway Severely Affects Tobacco Growth under Field, but Not Greenhouse Conditions
10.1186/s13104-022-06188-9 · 2022 · External reference
Conditional Modulation of NAD Levels and Metabolite Profiles in Nicotiana Sylvestris by Mitochondrial Electron Transport and Carbon/Nitrogen Supply
10.1007/s00425-010-1117-x · 2010 · External reference
Evolutionary Metabolomics of Specialized Metabolism Diversification in the Genus Nicotiana Highlights N-Acylnornicotine Innovations
10.1126/sciadv.ade8984 · 2023 · External reference
Neurobiological Mechanisms of Nicotine’s Effects on Feeding and Body Weight
10.1016/j.neubiorev.2025.106021 · 2025 · External reference
Effect of Nicotine on the Energy Metabolism of Substantia Nigra Cells in MPTP-Induced Parkinson’s Disease
10.22038/ijbms.2025.84754.18338 · 2025 · External reference
The Interpeduncular Nucleus Blunts the Rewarding Effect of Nicotine
10.1016/j.neuron.2025.03.035 · 2025 · External reference
E)-Nicotinaldehyde O-Cinnamyloxime, a Nicotine Analog, Attenuates Neuronal Cells Death Against Rotenone-Induced Neurotoxicity
10.1007/s12035-018-1163-0 · 2019 · External reference
Nicotine as a Potential Neuroprotective Agent for Parkinson’s Disease
10.1002/mds.25028 · 2012 · External reference
Naturally-Expressed Nicotinic Acetylcholine Receptor Subtypes
10.1016/j.bcp.2011.07.067 · 2011 · External reference
Nicotine Promotes Neuron Survival and Partially Protects from Parkinson’s Disease by Suppressing SIRT6
10.1186/s40478-018-0625-y · 2018 · External reference
The Role of BDNF/PI3K/AKT/Nrf2 Signaling in Nicotine’s Protective Effects against MPTP-Induced Parkinson’s Disease
10.1016/j.neulet.2025.138412 · 2025 · External reference
Sinomenine Regulates the Cholinergic Anti-Inflammatory Pathway to Inhibit TLR4/NF-κB Pathway and Protect the Homeostasis in Brain and Gut in Scopolamine-Induced Alzheimer’s Disease Mice
10.1016/j.biopha.2024.116190 · 2024 · External reference
Diminished A7 Nicotinic Acetylcholine Receptor (α7nAChR) Rescues Amyloid-β Induced Atrial Remodeling by Oxi-CaMKII/MAPK/AP-1 Axis-Mediated Mitochondrial Oxidative Stress
10.1016/j.redox.2022.102594 · 2023 · External reference
Pharmacotherapy of Cognitive Deficits in Schizophrenia
10.1017/s1092852913000771 · 2014 · External reference
Anxiolytic, Promnesic, Anti-Acetylcholinesterase and Antioxidant Effects of Cotinine and 6-Hydroxy-L-Nicotine in Scopolamine-Induced Zebrafish (Danio Rerio) Model of Alzheimer’s Disease
10.3390/antiox10020212 · 2021 · External reference
6-Hydroxy-3-Succinoylsemialdehyde-Pyridine as a Potential Inhibitor of Schizophrenia-Associated Enzyme
10.1007/s44371-024-00037-3 · 2024 · External reference
Nicotine versus 6-Hydroxy-l-Nicotine against Chlorisondamine Induced Memory Impairment and Oxidative Stress in the Rat Hippocampus
10.1016/j.biopha.2016.12.008 · 2017 · External reference
Enhanced Behavioral Response by Decreasing Brain Oxidative Stress to 6-Hydroxy-l-Nicotine in Alzheimer’s Disease Rat Model
10.1016/j.neulet.2015.02.014 · 2015 · External reference
Nicotine Exposure During Pregnancy and Postnatal Cognitive Outcomes: A Systematic Review and Meta-Analysis
10.1111/apa.70539 · 2026 · External reference
The Effects of Nicotine on Development
10.1542/peds.2019-1346 · 2020 · External reference
Association of Maternal Snuff Use and Smoking with Sudden Infant Death Syndrome: A National Register Study
10.1038/s41390-022-02463-4 · 2023 · External reference
Nicotinic Acetylcholine Receptor Redux: Discovery of Accessories Opens Therapeutic Vistas
10.1126/science.abg6539 · 2021 · External reference
Nicotine’s Defensive Function in Nature
10.1371/journal.pbio.0020217 · 2004 · External reference
Synthesis and Characterization of Schiff Base of Nicotinic Hydrazide as Antibacterial Agent along with in Vivo Wound Healing Activities and Atomic Force Microscopic Study of Bacterial Cell Wall Affected by Synthesized Compound
10.36721/pjps.2020.33.2.reg.675-683.1 · 2020 · External reference
Antimicrobial Activity of Nicotine against a Spectrum of Bacterial and Fungal Pathogens
10.1099/0022-1317-49-7-675 · 2000 · External reference
In Vitro Anthelmintic Effect of Tobacco (Nicotiana Tabacum) Extract on Parasitic Nematode, Marshallagia Marshalli
10.1007/s12639-014-0550-3 · 2016 · External reference
Antiparasitic Properties of Leaf Extracts Derived from Selected Nicotiana Species and Nicotiana Tabacum Varieties
10.1016/j.fct.2019.110660 · 2019 · External reference
Environmental Risks and Challenges Associated with Neonicotinoid Insecticides
10.1021/acs.est.7b06388 · 2018 · External reference
High Levels of Miticides and Agrochemicals in North American Apiaries: Implications for Honey Bee Health
10.1371/journal.pone.0009754 · 2010 · External reference
Bacterial Nicotine Derivatives as Green Corrosion Inhibitors: A Quantum Mechanical Perspective
10.1007/s42250-023-00759-4 · 2024 · External reference
RETRACTED ARTICLE: Computational Investigation of Microbial Nicotine Derivatives as Potential Pesticides
10.1007/s44371-025-00122-1 · 2025 · External reference
Molecular Effects of Neonicotinoids in Honey Bees (Apis mellifera)
10.1021/acs.est.6b00678 · 2016 · External reference
Residual Concentrations and Ecological Risks of Neonicotinoid Insecticides in the Soils of Tomato and Cucumber Greenhouses in Shouguang, Shandong Province, East China
10.1016/j.scitotenv.2020.140248 · 2020 · External reference
Occurrence and Ecological Risk Assessment of Neonicotinoids and Related Insecticides in the Bohai Sea and Its Surrounding Rivers, China
10.1016/j.watres.2021.117912 · 2022 · External reference
Insight into the Effects of Different Cropping Systems on Soil Bacterial Community and Tobacco Bacterial Wilt Rate
10.1002/jobm.201600222 · 2017 · External reference
Effect of Different Fertilizers on Functional Diversity of Microbial Flora in Rhizospheric Soil Under Tobacco Monoculture
10.1016/s1875-2780(11)60003-5 · 2011 · External reference
Reconstitution of Early Paclitaxel Biosynthetic Network
10.1038/s41467-024-45574-8 · 2024 · External reference
Chloroplastic Metabolic Engineering Coupled with Isoprenoid Pool Enhancement for Committed Taxanes Biosynthesis in Nicotiana Benthamiana
10.1038/s41467-019-12879-y · 2019 · External reference
A de Novo Regulation Design Shows an Effectiveness in Altering Plant Secondary Metabolism
10.1016/j.jare.2021.06.017 · 2022 · External reference
Nicotine: From Discovery to Biological Effects
10.3390/ijms241914570 · 2023 · External reference
Nicotine Chemistry, Metabolism, Kinetics and Biomarkers
10.1007/978-3-540-69248-5_2 · 2009 · External reference
Genetic Regulation and Manipulation of Nicotine Biosynthesis in Tobacco: Strategies to Eliminate Addictive Alkaloids
10.1093/jxb/erad341 · 2024 · External reference
Integrating Transcriptome and Metabolome Reveals Molecular Networks Involved in Genetic and Environmental Variation in Tobacco
10.1093/dnares/dsaa006 · 2020 · External reference
Enantiomeric Composition of Nicotine in Smokeless Tobacco, Medicinal Products, and Commercial Reagents
10.1002/(sici)1520-636x(1998)10:73.0.co;2-# · ExternalCitation · doi-reference
Crystal Structures of a Nicotine MATE Transporter Provide Insight into Its Mechanism of Substrate Transport
10.1002/1873-3468.14136 · ExternalCitation · doi-reference
Insight into the Effects of Different Cropping Systems on Soil Bacterial Community and Tobacco Bacterial Wilt Rate
10.1002/jobm.201600222 · ExternalCitation · doi-reference
Nicotine as a Potential Neuroprotective Agent for Parkinson’s Disease
10.1002/mds.25028 · ExternalCitation · doi-reference
Effects of Overexpression of Jasmonic Acid Biosynthesis Genes on Nicotine Accumulation in Tobacco
10.1002/pld3.36 · ExternalCitation · doi-reference
Nicotine Chemistry, Metabolism, Kinetics and Biomarkers
10.1007/978-3-540-69248-5_2 · ExternalCitation · doi-reference
The Defensive Chemistry of Ants
10.1007/978-3-7091-6341-2_2 · ExternalCitation · doi-reference
Dufour’s Gland and Poison Gland Chemistry of the Myrmicine Ant,Messor Capensis (Mayr)
10.1007/bf00984878 · ExternalCitation · doi-reference
Trail-Following Behaviour in Two Aphaenogaster Ants
10.1007/s00049-011-0071-9 · ExternalCitation · doi-reference
Conditional Modulation of NAD Levels and Metabolite Profiles in Nicotiana Sylvestris by Mitochondrial Electron Transport and Carbon/Nitrogen Supply
10.1007/s00425-010-1117-x · ExternalCitation · doi-reference
Genetic Attenuation of Alkaloids and Nicotine Content in Tobacco (Nicotiana tabacum)
10.1007/s00425-020-03387-1 · ExternalCitation · doi-reference
Silencing of PMT Expression Caused a Surge of Anatabine Accumulation in Tobacco
10.1007/s11033-009-9446-1 · ExternalCitation · doi-reference
A PIP-Family Protein Is Required for Biosynthesis of Tobacco Alkaloids
10.1007/s11103-008-9424-3 · ExternalCitation · doi-reference
The A622 Gene in Nicotiana glauca (Tree Tobacco): Evidence for a Functional Role in Pyridine Alkaloid Synthesis
10.1007/s11103-008-9425-2 · ExternalCitation · doi-reference
Transcriptomic Analysis Provides Insights into the AUXIN RESPONSE FACTOR 6-Mediated Repression of Nicotine Biosynthesis in Tobacco (Nicotiana tabacum L.)
10.1007/s11103-021-01175-3 · ExternalCitation · doi-reference
E)-Nicotinaldehyde O-Cinnamyloxime, a Nicotine Analog, Attenuates Neuronal Cells Death Against Rotenone-Induced Neurotoxicity
10.1007/s12035-018-1163-0 · ExternalCitation · doi-reference
Generation of Tobacco Lines with Widely Different Reduction in Nicotine Levels via RNA Silencing Approaches
10.1007/s12038-008-0035-6 · ExternalCitation · doi-reference
In Vitro Anthelmintic Effect of Tobacco (Nicotiana Tabacum) Extract on Parasitic Nematode, Marshallagia Marshalli
10.1007/s12639-014-0550-3 · ExternalCitation · doi-reference
Bacterial Nicotine Derivatives as Green Corrosion Inhibitors: A Quantum Mechanical Perspective
10.1007/s42250-023-00759-4 · ExternalCitation · doi-reference
6-Hydroxy-3-Succinoylsemialdehyde-Pyridine as a Potential Inhibitor of Schizophrenia-Associated Enzyme
10.1007/s44371-024-00037-3 · ExternalCitation · doi-reference
RETRACTED ARTICLE: Computational Investigation of Microbial Nicotine Derivatives as Potential Pesticides
10.1007/s44371-025-00122-1 · ExternalCitation · doi-reference
Naturally-Expressed Nicotinic Acetylcholine Receptor Subtypes
10.1016/j.bcp.2011.07.067 · ExternalCitation · doi-reference
Nicotine versus 6-Hydroxy-l-Nicotine against Chlorisondamine Induced Memory Impairment and Oxidative Stress in the Rat Hippocampus
10.1016/j.biopha.2016.12.008 · ExternalCitation · doi-reference
Sinomenine Regulates the Cholinergic Anti-Inflammatory Pathway to Inhibit TLR4/NF-κB Pathway and Protect the Homeostasis in Brain and Gut in Scopolamine-Induced Alzheimer’s Disease Mice
10.1016/j.biopha.2024.116190 · ExternalCitation · doi-reference
Complete Biosynthesis of Nicotine
10.1016/j.cell.2026.03.034 · ExternalCitation · doi-reference
Bacterial Catabolism of Nicotine: Catabolic Strains, Pathways and Modules
10.1016/j.envres.2020.109258 · ExternalCitation · doi-reference
Antiparasitic Properties of Leaf Extracts Derived from Selected Nicotiana Species and Nicotiana Tabacum Varieties
10.1016/j.fct.2019.110660 · ExternalCitation · doi-reference
A de Novo Regulation Design Shows an Effectiveness in Altering Plant Secondary Metabolism
10.1016/j.jare.2021.06.017 · ExternalCitation · doi-reference
Mutation in Shoot-to-Root Mobile Transcription Factor, Elongated Hypocotyl 5, Leads to Low Nicotine Levels in Tobacco
10.1016/j.jhazmat.2023.133255 · ExternalCitation · doi-reference
Neurobiological Mechanisms of Nicotine’s Effects on Feeding and Body Weight
10.1016/j.neubiorev.2025.106021 · ExternalCitation · doi-reference
Enhanced Behavioral Response by Decreasing Brain Oxidative Stress to 6-Hydroxy-l-Nicotine in Alzheimer’s Disease Rat Model
10.1016/j.neulet.2015.02.014 · ExternalCitation · doi-reference
The Role of BDNF/PI3K/AKT/Nrf2 Signaling in Nicotine’s Protective Effects against MPTP-Induced Parkinson’s Disease
10.1016/j.neulet.2025.138412 · ExternalCitation · doi-reference
The Interpeduncular Nucleus Blunts the Rewarding Effect of Nicotine
10.1016/j.neuron.2025.03.035 · ExternalCitation · doi-reference
The Role of the Bemisia Tabaci and Trialeurodes Vaporariorum Cytochrome-P450 Clade CYP6DPx in Resistance to Nicotine and Neonicotinoids
10.1016/j.pestbp.2023.105743 · ExternalCitation · doi-reference
An in Silico Pipeline for Enzyme-Substrate Modelling Using Arthropod P450s
10.1016/j.pestbp.2025.106816 · ExternalCitation · doi-reference
Cloning and Characterization of a Nicotiana tabacum Methylputrescine Oxidase Transcript
10.1016/j.phytochem.2006.11.003 · ExternalCitation · doi-reference
BBL Enzymes Exhibit Enantiospecific Preferences in the Biosynthesis of Pyridine Alkaloids in Nicotiana Tabacum L
10.1016/j.phytochem.2024.114363 · ExternalCitation · doi-reference
ABA-INSENSITIVE 4 Promotes Nicotine Biosynthesis under High Light in Nicotiana Attenuata
10.1016/j.plantsci.2025.112416 · ExternalCitation · doi-reference
Low H3K27me3 Deposition at CYP82E4 Determines the Nicotinic Conversion Rate in Nicotiana Tabacum
10.1016/j.plaphy.2023.108234 · ExternalCitation · doi-reference
Advances in Regulatory Mechanism(s) and Biotechnological Approaches to Modulate Nicotine Content in Tobacco
10.1016/j.plaphy.2024.108397 · ExternalCitation · doi-reference
Gamma-Aminobutyric Acid Mediates Nicotine Biosynthesis in Tobacco under Flooding Stress
10.1016/j.pld.2016.05.004 · ExternalCitation · doi-reference
Jasmonate Mediates Salt-Induced Nicotine Biosynthesis in Tobacco (Nicotiana tabacum L.)
10.1016/j.pld.2016.06.001 · ExternalCitation · doi-reference
Diminished A7 Nicotinic Acetylcholine Receptor (α7nAChR) Rescues Amyloid-β Induced Atrial Remodeling by Oxi-CaMKII/MAPK/AP-1 Axis-Mediated Mitochondrial Oxidative Stress
10.1016/j.redox.2022.102594 · ExternalCitation · doi-reference
Residual Concentrations and Ecological Risks of Neonicotinoid Insecticides in the Soils of Tomato and Cucumber Greenhouses in Shouguang, Shandong Province, East China
10.1016/j.scitotenv.2020.140248 · ExternalCitation · doi-reference
Biochar-Mediated Changes in Soil Quality and Plant Growth in a Three Year Field Trial
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Occurrence and Ecological Risk Assessment of Neonicotinoids and Related Insecticides in the Bohai Sea and Its Surrounding Rivers, China
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