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References from Enantioselective Synthesis of Spiropyrrolidines by Synergistic Catalysis. Local targets link to admitted publications; unresolved targets remain external evidence.
Pyrrolidine in Drug Discovery: A Versatile Scaffold for Novel Biologically Active Compounds
10.1007/s41061-021-00347-5 · 2021 · External reference
Therapeutic Potential of Pyrrole and Pyrrolidine Analogs: An Update
10.1007/s11030-022-10387-8 · 2022 · External reference
Recent Insights about Pyrrolidine Core Skeletons in Pharmacology
10.3389/fphar.2023.1239658 · 2023 · External reference
Novel Phenyl and Thiophene Dispiro Indenoquinoxaline Pyrrolidine Quinolones Induced Apoptosis via G1/S and G2/M Phase Cell Cycle Arrest in MCF-7 Cells
10.1039/d0nj02588g · 2020 · External reference
Structure Activity Relationship (SAR) and Anticancer Activity of Pyrrolidine Derivatives: Recent Developments and Future Prospects (A Review)
10.1016/j.ejmech.2022.114954 · 2023 · External reference
Antiproliferative 3-Deoxysphingomyelin Analogs: Design, Synthesis, Biological Evaluation and Molecular Docking of Pyrrolidine-Based 3-Deoxysphingomyelin Analogs as Anticancer Agents
10.1016/j.bioorg.2018.11.040 · 2019 · External reference
Glucosamine-6-Phosphate Synthase Inhibiting C3-β-Cholesterol Tethered Spiro Heterocyclic Conjugates: Synthesis and Their Insight of DFT and Docking Study
10.1016/j.bioorg.2019.102920 · 2019 · External reference
Synthesis of Substituted N-(2′-Nitrophenyl)Pyrrolidine-2-Carboxamides towards the Design of Proline-Rich Antimicrobial Peptide Mimics to Eliminate Bacterial Resistance to Antibiotics
10.1016/j.bioorg.2020.104340 · 2020 · External reference
Recent Advances in Organocatalytic Asymmetric Synthesis of Polysubstituted Pyrrolidines
10.1016/j.tetlet.2013.11.048 · 2014 · External reference
Stereochemical Diversity in Pyrrolidine Synthesis by Catalytic Asymmetric 1,3-Dipolar Cycloaddition of Azomethine Ylides
10.1039/c9cc05238k · 2019 · External reference
Organocatalytic Enantioselective [3 + 2] Cycloaddition of Azomethine Ylides and a, b -Unsaturated Aldehydes**
10.1002/anie.200700988 · 2007 · External reference
The Organocatalytic [3+2] Cycloaddition of Azomethine Ylides and α,β-Unsaturated Aldehydes as a Convenient Tool for the Enantioselective Synthesis of Pyrrolizidines and Indolizidines
10.1039/c001274b · 2010 · External reference
10.1002/adsc.201100432
10.1002/adsc.201100432 · 2011 · External reference
An Amine-Catalyzed Enantioselective [3+2] Cycloaddition of Azomethine Ylides and α,β-Unsaturated Aldehydes: Applications and Mechanistic Implications
10.1002/chem.201103015 · 2012 · External reference
Dynamic One-Pot Three-Component Catalytic Asymmetric Transformation by Combination of Hydrogen-Bond-Donating and Amine Catalysts **
10.1002/anie.201101966 · 2011 · External reference
Enantioselective Organo-SOMO Cycloadditions: A Catalytic Approach to Complex Pyrrolidines from Olefins and Aldehydes
10.1021/ja305076b · 2012 · External reference
Asymmetric Organocatalytic Formal Double-Arylation of Azomethines for the Synthesis of Highly Enantiomerically Enriched Isoindolines
10.1039/b917246g · 2010 · External reference
Organocatalytic Asymmetric Intramolecular [3+2] Cycloaddition: A Straightforward Approach to Access Multiply Substituted Hexahydrochromeno[4,3-b]Pyrrolidine Derivatives in High Optical Purity
10.1039/c002369h · 2010 · External reference
Asymmetic Organocatalytic 1,3-Dipolar Cycloaddition of Azomethine Ylide to Methyl 2-(2-Nitrophenyl)Acrylate for the Synthesis of Diastereoisomers of Spirotryprostatin A
10.1021/ol200652j · 2011 · External reference
Binaphthol-Derived Bisphosphoric Acids Serve as Efficient Organocatalysts for Highly Enantioselective 1,3-Dipolar Cycloaddition of Azomethine Ylides to Electron-Deficient Olefins
10.1021/ja204218h · 2011 · External reference
10.1002/chem.201200358
10.1002/chem.201200358 · 2012 · External reference
Biomimetic Asymmetric 1,3-Dioplar Cycloaddition: Amino Acid Precursors in Biosynthesis Serve as Latent Azomethine Ylides
10.1021/ol400983j · 2013 · External reference
Metal-Free Asymmetric 1, 3-Dipolar Cycloaddition of N -Arylmaleimides to Azomethine Ylides Catalyzed by Chiral Tertiary Amine Thiourea
10.1002/ejoc.201100205 · 2011 · External reference
Organocatalytic Stereocontrolled Synthesis of 3,3′-Pyrrolidinyl Spirooxindoles by [3+2] Annulation of Isocyanoesters with Methyleneindolinones
10.1039/c2cc30746d · 2012 · External reference
Efficient Construction of Highly Functionalized Spiro[γ-Butyrolactone-Pyrrolidin-3,3′-Oxindole] Tricyclic Skeletons via an Organocatalytic 1,3-Dipolar Cycloaddition
10.1039/c3cc40669e · 2013 · External reference
Synergistic Catalysis: A Powerful Synthetic Strategy for New Reaction Development
10.1039/c2sc00907b · 2012 · External reference
Combining Transition Metal Catalysis and Organocatalysis: A Broad New Concept for Catalysis
10.1039/b901258n · 2009 · External reference
Combining Transition Metal Catalysis and Organocatalysis–an Update
10.1039/c2cs35258c · 2013 · External reference
Combinations of Aminocatalysts and Metal Catalysts: A Powerful Cooperative Approach in Selective Organic Synthesis
10.1021/acs.chemrev.6b00226 · 2016 · External reference
Cooperative Catalysis with Chiral Brønsted Acid-Rh2(OAc)4: Highly Enantioselective Three-Component Reactions of Diazo Compounds with Alcohols and Imines
10.1021/ja801755z · 2008 · External reference
Selectivity Control in Enantioselective Four-Component Reactions of Aryl Diazoacetates with Alcohols, Aldehydes and Amines: An Efficient Approach to Synthesizing Chiral β-Amino-α-Hydroxyesters
10.1039/b816104f · 2008 · External reference
Chiral Counteranions in Asymmetric Transition-Metal Catalysis: Highly Enantioselective Pd/Brønsted Acid-Catalyzed Direct α-Allylation of Aldehydes
10.1021/ja074678r · 2007 · External reference
Asymmetric Preparation of Polysubstituted Cyclopentanes by Synergistic Pd(0)/Amine Catalyzed Formal [3+2] Cycloadditions of Vinyl Cyclopropanes with Enals
10.1039/c6cc01775d · 2016 · External reference
Asymmetric [3 + 2] Cycloaddition of Vinylcyclopropanes and α,β-Unsaturated Aldehydes by Synergistic Palladium and Organocatalysis
10.1021/acs.orglett.6b00852 · 2016 · External reference
10.1002/chem.201601893
10.1002/chem.201601893 · 2016 · External reference
Pd-Catalyzed Diastereoselective [3 + 2] Cycloaddition of Vinylcyclopropanes with Sulfamate-Derived Cyclic Imines
10.1039/c8ob01231h · 2018 · External reference
Palladium(0)-Catalyzed Diastereoselective (3+2) Cycloadditions of Vinylcyclopropanes with Sulfonyl-Activated Imines
10.1055/s-0037-1609625 · 2018 · External reference
Vinyl-Aziridines and Cyclopropanes in Pd-Catalyzed (3+2)-Cycloaddition Reactions with Cyclic N-Sulfonyl Imines
10.1016/j.tet.2018.09.040 · 2018 · External reference
Fe-Catalyzed Allylic C–C-Bond Activation: Vinylcyclopropanes As Versatile A1,A3,D5-Synthons in Traceless Allylic Substitutions and [3 + 2]-Cycloadditions
10.1021/ja300294a · 2012 · External reference
Insertion of Imines into Vinylcyclopropanes Catalyzed by Nucleophilic Iron Complexes: A Formal [3+2]-Cycloaddition Strategy for the Synthesis of Substituted Pyrrolidine Derivatives
10.1055/s-0034-1379180 · 2014 · External reference
Nickel-Catalyzed Cycloaddition of Vinylcyclopropanes to Imines
10.1021/ol4005068 · 2013 · External reference
Palladium-Catalyzed Highly Enantioselective Cycloaddition of Vinyl Cyclopropanes with Imines
10.1021/acs.orglett.9b00274 · 2019 · External reference
Synergistic Palladium-Phosphoric Acid Catalysis in (3 + 2) Cycloaddition Reactions between Vinylcyclopropanes and Imines
10.3390/catal10020150 · 2020 · External reference
Enantioselective Synthesis of Spiro Heterocyclic Compounds Using a Combination of Organocatalysis and Transition-Metal Catalysis
10.1002/tcr.202200284 · 2023 · External reference
Synergistic Formal Ring Contraction for the Enantioselective Synthesis of Spiropyrazolones
10.1039/c8sc00913a · 2018 · External reference
Formal [3+2] Cycloaddition of Vinylcyclopropane Azlactones to Enals Using Synergistic Catalysis
10.1039/c8cc06500d · 2019 · External reference
Enantioselective Synthesis of Spirothiazolones via Cooperative Catalysis
10.1002/adsc.202100571 · 2021 · External reference
Enantioselective Synthesis of Spiroimidazolones by Synergistic Catalysis
10.1016/j.cattod.2023.114443 · 2024 · External reference
B(C6F5)3/Chiral Phosphoric Acid Catalyzed Ketimine–Ene Reaction of 2-Aryl-3H-Indol-3-Ones and α-Methylstyrenes
10.1002/anie.201915226 · 2020 · External reference
Enantio- and Diastereoselective Carbonyl-Ene Cyclization–Acetalization Tandem Reaction Catalyzed by Tris(Pentafluorophenyl)Borane-Assisted Chiral Phosphoric Acids
10.1021/acscatal.1c01242 · 2021 · External reference
10.1002/adsc.201100432
10.1002/adsc.201100432 · ExternalCitation · doi-reference
Enantioselective Synthesis of Spirothiazolones via Cooperative Catalysis
10.1002/adsc.202100571 · ExternalCitation · doi-reference
Organocatalytic Enantioselective [3 + 2] Cycloaddition of Azomethine Ylides and a, b -Unsaturated Aldehydes**
10.1002/anie.200700988 · ExternalCitation · doi-reference
Dynamic One-Pot Three-Component Catalytic Asymmetric Transformation by Combination of Hydrogen-Bond-Donating and Amine Catalysts **
10.1002/anie.201101966 · ExternalCitation · doi-reference
B(C6F5)3/Chiral Phosphoric Acid Catalyzed Ketimine–Ene Reaction of 2-Aryl-3H-Indol-3-Ones and α-Methylstyrenes
10.1002/anie.201915226 · ExternalCitation · doi-reference
An Amine-Catalyzed Enantioselective [3+2] Cycloaddition of Azomethine Ylides and α,β-Unsaturated Aldehydes: Applications and Mechanistic Implications
10.1002/chem.201103015 · ExternalCitation · doi-reference
10.1002/chem.201200358
10.1002/chem.201200358 · ExternalCitation · doi-reference
10.1002/chem.201601893
10.1002/chem.201601893 · ExternalCitation · doi-reference
Metal-Free Asymmetric 1, 3-Dipolar Cycloaddition of N -Arylmaleimides to Azomethine Ylides Catalyzed by Chiral Tertiary Amine Thiourea
10.1002/ejoc.201100205 · ExternalCitation · doi-reference
Enantioselective Synthesis of Spiro Heterocyclic Compounds Using a Combination of Organocatalysis and Transition-Metal Catalysis
10.1002/tcr.202200284 · ExternalCitation · doi-reference
Therapeutic Potential of Pyrrole and Pyrrolidine Analogs: An Update
10.1007/s11030-022-10387-8 · ExternalCitation · doi-reference
Pyrrolidine in Drug Discovery: A Versatile Scaffold for Novel Biologically Active Compounds
10.1007/s41061-021-00347-5 · ExternalCitation · doi-reference
Antiproliferative 3-Deoxysphingomyelin Analogs: Design, Synthesis, Biological Evaluation and Molecular Docking of Pyrrolidine-Based 3-Deoxysphingomyelin Analogs as Anticancer Agents
10.1016/j.bioorg.2018.11.040 · ExternalCitation · doi-reference
Glucosamine-6-Phosphate Synthase Inhibiting C3-β-Cholesterol Tethered Spiro Heterocyclic Conjugates: Synthesis and Their Insight of DFT and Docking Study
10.1016/j.bioorg.2019.102920 · ExternalCitation · doi-reference
Synthesis of Substituted N-(2′-Nitrophenyl)Pyrrolidine-2-Carboxamides towards the Design of Proline-Rich Antimicrobial Peptide Mimics to Eliminate Bacterial Resistance to Antibiotics
10.1016/j.bioorg.2020.104340 · ExternalCitation · doi-reference
Enantioselective Synthesis of Spiroimidazolones by Synergistic Catalysis
10.1016/j.cattod.2023.114443 · ExternalCitation · doi-reference
Structure Activity Relationship (SAR) and Anticancer Activity of Pyrrolidine Derivatives: Recent Developments and Future Prospects (A Review)
10.1016/j.ejmech.2022.114954 · ExternalCitation · doi-reference
Vinyl-Aziridines and Cyclopropanes in Pd-Catalyzed (3+2)-Cycloaddition Reactions with Cyclic N-Sulfonyl Imines
10.1016/j.tet.2018.09.040 · ExternalCitation · doi-reference
Recent Advances in Organocatalytic Asymmetric Synthesis of Polysubstituted Pyrrolidines
10.1016/j.tetlet.2013.11.048 · ExternalCitation · doi-reference
Combinations of Aminocatalysts and Metal Catalysts: A Powerful Cooperative Approach in Selective Organic Synthesis
10.1021/acs.chemrev.6b00226 · ExternalCitation · doi-reference
Asymmetric [3 + 2] Cycloaddition of Vinylcyclopropanes and α,β-Unsaturated Aldehydes by Synergistic Palladium and Organocatalysis
10.1021/acs.orglett.6b00852 · ExternalCitation · doi-reference
Palladium-Catalyzed Highly Enantioselective Cycloaddition of Vinyl Cyclopropanes with Imines
10.1021/acs.orglett.9b00274 · ExternalCitation · doi-reference
Enantio- and Diastereoselective Carbonyl-Ene Cyclization–Acetalization Tandem Reaction Catalyzed by Tris(Pentafluorophenyl)Borane-Assisted Chiral Phosphoric Acids
10.1021/acscatal.1c01242 · ExternalCitation · doi-reference
Chiral Counteranions in Asymmetric Transition-Metal Catalysis: Highly Enantioselective Pd/Brønsted Acid-Catalyzed Direct α-Allylation of Aldehydes
10.1021/ja074678r · ExternalCitation · doi-reference
Binaphthol-Derived Bisphosphoric Acids Serve as Efficient Organocatalysts for Highly Enantioselective 1,3-Dipolar Cycloaddition of Azomethine Ylides to Electron-Deficient Olefins
10.1021/ja204218h · ExternalCitation · doi-reference
Fe-Catalyzed Allylic C–C-Bond Activation: Vinylcyclopropanes As Versatile A1,A3,D5-Synthons in Traceless Allylic Substitutions and [3 + 2]-Cycloadditions
10.1021/ja300294a · ExternalCitation · doi-reference
Enantioselective Organo-SOMO Cycloadditions: A Catalytic Approach to Complex Pyrrolidines from Olefins and Aldehydes
10.1021/ja305076b · ExternalCitation · doi-reference
Cooperative Catalysis with Chiral Brønsted Acid-Rh2(OAc)4: Highly Enantioselective Three-Component Reactions of Diazo Compounds with Alcohols and Imines
10.1021/ja801755z · ExternalCitation · doi-reference
Asymmetic Organocatalytic 1,3-Dipolar Cycloaddition of Azomethine Ylide to Methyl 2-(2-Nitrophenyl)Acrylate for the Synthesis of Diastereoisomers of Spirotryprostatin A
10.1021/ol200652j · ExternalCitation · doi-reference
Nickel-Catalyzed Cycloaddition of Vinylcyclopropanes to Imines
10.1021/ol4005068 · ExternalCitation · doi-reference
Biomimetic Asymmetric 1,3-Dioplar Cycloaddition: Amino Acid Precursors in Biosynthesis Serve as Latent Azomethine Ylides
10.1021/ol400983j · ExternalCitation · doi-reference
Selectivity Control in Enantioselective Four-Component Reactions of Aryl Diazoacetates with Alcohols, Aldehydes and Amines: An Efficient Approach to Synthesizing Chiral β-Amino-α-Hydroxyesters
10.1039/b816104f · ExternalCitation · doi-reference
Combining Transition Metal Catalysis and Organocatalysis: A Broad New Concept for Catalysis
10.1039/b901258n · ExternalCitation · doi-reference
Asymmetric Organocatalytic Formal Double-Arylation of Azomethines for the Synthesis of Highly Enantiomerically Enriched Isoindolines
10.1039/b917246g · ExternalCitation · doi-reference
The Organocatalytic [3+2] Cycloaddition of Azomethine Ylides and α,β-Unsaturated Aldehydes as a Convenient Tool for the Enantioselective Synthesis of Pyrrolizidines and Indolizidines
10.1039/c001274b · ExternalCitation · doi-reference
Organocatalytic Asymmetric Intramolecular [3+2] Cycloaddition: A Straightforward Approach to Access Multiply Substituted Hexahydrochromeno[4,3-b]Pyrrolidine Derivatives in High Optical Purity
10.1039/c002369h · ExternalCitation · doi-reference
Organocatalytic Stereocontrolled Synthesis of 3,3′-Pyrrolidinyl Spirooxindoles by [3+2] Annulation of Isocyanoesters with Methyleneindolinones
10.1039/c2cc30746d · ExternalCitation · doi-reference
Combining Transition Metal Catalysis and Organocatalysis–an Update
10.1039/c2cs35258c · ExternalCitation · doi-reference
Synergistic Catalysis: A Powerful Synthetic Strategy for New Reaction Development
10.1039/c2sc00907b · ExternalCitation · doi-reference
Efficient Construction of Highly Functionalized Spiro[γ-Butyrolactone-Pyrrolidin-3,3′-Oxindole] Tricyclic Skeletons via an Organocatalytic 1,3-Dipolar Cycloaddition
10.1039/c3cc40669e · ExternalCitation · doi-reference
Asymmetric Preparation of Polysubstituted Cyclopentanes by Synergistic Pd(0)/Amine Catalyzed Formal [3+2] Cycloadditions of Vinyl Cyclopropanes with Enals
10.1039/c6cc01775d · ExternalCitation · doi-reference
Formal [3+2] Cycloaddition of Vinylcyclopropane Azlactones to Enals Using Synergistic Catalysis
10.1039/c8cc06500d · ExternalCitation · doi-reference
Pd-Catalyzed Diastereoselective [3 + 2] Cycloaddition of Vinylcyclopropanes with Sulfamate-Derived Cyclic Imines
10.1039/c8ob01231h · ExternalCitation · doi-reference
Synergistic Formal Ring Contraction for the Enantioselective Synthesis of Spiropyrazolones
10.1039/c8sc00913a · ExternalCitation · doi-reference
Stereochemical Diversity in Pyrrolidine Synthesis by Catalytic Asymmetric 1,3-Dipolar Cycloaddition of Azomethine Ylides
10.1039/c9cc05238k · ExternalCitation · doi-reference
Novel Phenyl and Thiophene Dispiro Indenoquinoxaline Pyrrolidine Quinolones Induced Apoptosis via G1/S and G2/M Phase Cell Cycle Arrest in MCF-7 Cells
10.1039/d0nj02588g · ExternalCitation · doi-reference
Insertion of Imines into Vinylcyclopropanes Catalyzed by Nucleophilic Iron Complexes: A Formal [3+2]-Cycloaddition Strategy for the Synthesis of Substituted Pyrrolidine Derivatives
10.1055/s-0034-1379180 · ExternalCitation · doi-reference
Palladium(0)-Catalyzed Diastereoselective (3+2) Cycloadditions of Vinylcyclopropanes with Sulfonyl-Activated Imines
10.1055/s-0037-1609625 · ExternalCitation · doi-reference
Recent Insights about Pyrrolidine Core Skeletons in Pharmacology
10.3389/fphar.2023.1239658 · ExternalCitation · doi-reference
Synergistic Palladium-Phosphoric Acid Catalysis in (3 + 2) Cycloaddition Reactions between Vinylcyclopropanes and Imines
10.3390/catal10020150 · ExternalCitation · doi-reference
