Research graph
References from Direct C6-Alkynylation of Indoles by Palladium/Norbornene Cooperative Catalysis. Local targets link to admitted publications; unresolved targets remain external evidence.
Discovery of Potent and Brain-Penetrant Tau Tubulin Kinase 1 (TTBK1) Inhibitors that Lower Tau Phosphorylation In Vivo
10.1021/acs.jmedchem.1c00382 · 2021 · External reference
6H-Indolo-[2,3-b]-quinoxaline derivatives as promising bifunctional SHP1 inhibitors
10.1039/d4ob01492h · 2025 · External reference
Design, Synthesis, and Biological Evaluation of Selective PAK4 Degrader for the Treatment of Lung Tumor Metastasis
10.1021/acs.jmedchem.5c00197 · 2025 · External reference
Beyond C2 and C3: Transition-Metal-Catalyzed C–H Functionalization of Indole
10.1021/acscatal.7b01785 · 2017 · External reference
From C4 to C7: Innovative Strategies for Site-Selective Functionalization of Indole C–H Bonds
10.1021/acs.accounts.0c00888 · 2021 · External reference
Site-selective C-H functionalization to access the arene backbone of indoles and quinolines
10.1039/d0cs00334d · 2021 · External reference
Transition metal-catalyzed C–H functionalizations of indoles
10.1039/d1nj01696b · 2021 · External reference
Pd(II)-Catalyzed meta-C–H Olefination, Arylation, and Acetoxylation of Indolines Using a U-Shaped Template
10.1021/ja505737x · 2014 · External reference
Total Synthesis of Verruculogen and Fumitremorgin A Enabled by Ligand-Controlled C–H Borylation
10.1021/jacs.5b07154 · 2015 · External reference
Cu-Catalyzed Direct C6-Arylation of Indoles
10.1021/jacs.6b05777 · 2016 · External reference
Remote C6-Selective Ruthenium-Catalyzed C–H Alkylation of Indole Derivatives via σ-Activation
10.1021/acscatal.7b00038 · 2017 · External reference
Chiral Phosphoric Acid-Catalyzed C6 Functionalization of 2,3-Disubstituted Indoles for Synthesis of Heterotriarylmethanes
10.1021/acs.orglett.0c04002 · 2021 · External reference
Catalytic C6 Functionalization of 2,3-Disubstituted Indoles by Scandium Triflate
10.1021/jo402511b · 2014 · External reference
Remote Stereocontrol in the C6-Functionalization of Indoles via Synergistic Ion-Pair Catalysis
10.1021/acscatal.5c00780 · 2025 · External reference
Dispersion-controlled C6-selective C–H borylation of indoles
10.1039/d5cc01554e · 2025 · External reference
Pd/Norbornene: A Winning Combination for Selective Aromatic Functionalization via C–H Bond Activation
10.1021/acs.accounts.6b00165 · 2016 · External reference
Palladium/Norbornene Cooperative Catalysis
10.1021/acs.chemrev.9b00079 · 2019 · External reference
Structurally Modified Norbornenes: A Key Factor to Modulate Reaction Selectivity in the Palladium/Norbornene Cooperative Catalysis
10.1021/jacs.0c09193 · 2020 · External reference
Palladium(II)-Initiated Catellani-Type Reactions
10.1002/anie.201813491 · 2019 · External reference
Catellani Reaction: An Enabling Technology for Vicinal Functionalization of Aryl Halides by Palladium(0)/Norbornene Cooperative Catalysis
10.1002/cjoc.202000600 · 2021 · External reference
Triple cross-electrophile coupling enabled by palladium/norbornene cooperative catalysis
10.1126/sciadv.adu4573 · 2025 · External reference
Regioselective one-step C2-H methylation of free (N-H) indoles enabled by Pd(II)/norbornene cooperative catalysis
10.1039/d5qo00869g · 2025 · External reference
Ligand-enabled meta-C-H activation using a transient mediator
10.1038/nature14214 · 2015 · External reference
Ligand-Enabled Meta-C–H Alkylation and Arylation Using a Modified Norbornene
10.1021/jacs.5b08914 · 2015 · External reference
Ligand-Enabled meta-Selective C–H Arylation of Nosyl-Protected Phenethylamines, Benzylamines, and 2-Aryl Anilines
10.1021/jacs.6b11097 · 2017 · External reference
Ligand-Promoted meta-C–H Amination and Alkynylation
10.1021/jacs.6b08942 · 2016 · External reference
Ligand-Promoted Meta-C–H Arylation of Anilines, Phenols, and Heterocycles
10.1021/jacs.6b04966 · 2016 · External reference
Ligand Promoted meta-C–H Chlorination of Anilines and Phenols
10.1021/jacs.6b11055 · 2016 · External reference
meta-C–H Arylation and Alkylation of Benzylsulfonamide Enabled by a Palladium(II)/Isoquinoline Catalyst
10.1002/anie.201704411 · 2017 · External reference
Ligand-Enabled Auxiliary-Free meta-C–H Arylation of Phenylacetic Acids
10.1002/anie.201702686 · 2017 · External reference
Ligand-Promoted meta-C–H Functionalization of Benzylamines
10.1002/anie.201701803 · 2017 · External reference
Palladium-Catalyzed meta-C–H Functionalization of Masked Aromatic Aldehydes
10.1021/acscatal.8b01599 · 2018 · External reference
Differentiation and functionalization of remote C–H bonds in adjacent positions
10.1038/s41557-020-0424-5 · 2020 · External reference
meta-C–H functionalization of phenylethyl and benzylic alcohol derivatives via Pd/NBE relay catalysis
10.1039/d4sc03802a · 2024 · External reference
Palladium(II)-Catalyzed Direct C7-Acyloxylation of Indoles
10.1021/acs.orglett.5c04739 · 2026 · External reference
Advancing the Logic of Chemical Synthesis: C–H Activation as Strategic and Tactical Disconnections for C–C Bond Construction
10.1002/anie.202011901 · 2021 · External reference
Palladium (II)-Catalyzed C–H Activation with Bifunctional Ligands: From Curiosity to Industrialization
10.1002/anie.202400509 · 2024 · External reference
From Pd(OAc)2 to Chiral Catalysts: The Discovery and Development of Bifunctional Mono-N-Protected Amino Acid Ligands for Diverse C–H Functionalization Reactions
10.1021/acs.accounts.9b00621 · 2020 · External reference
Complementary site-selectivity in arene functionalization enabled by overcoming the orthoconstraint in palladium/norbornene catalysis
10.1038/s41557-018-0074-z · 2018 · External reference
Entry to 1,2,3,4-Tetrasubstituted Arenes through Addressing the “Meta Constraint” in the Palladium/Norbornene Catalysis
10.1021/jacs.9b12355 · 2020 · External reference
Modular and regioselective synthesis of all-carbon tetrasubstituted olefins enabled by an alkenyl Catellani reaction
10.1038/s41557-019-0358-y · 2019 · External reference
Regioisomeric π-Extended Nanographene with Long-Lived Phosphorescence Afterglow
10.1002/anie.202422125 · 2025 · External reference
Electrically driven directional motion of a four-wheeled molecule on a metal surface
10.1038/nature10587 · 2011 · External reference
Ligand-Promoted meta-C–H Functionalization of Benzylamines
10.1002/anie.201701803 · ExternalCitation · doi-reference
Ligand-Enabled Auxiliary-Free meta-C–H Arylation of Phenylacetic Acids
10.1002/anie.201702686 · ExternalCitation · doi-reference
meta-C–H Arylation and Alkylation of Benzylsulfonamide Enabled by a Palladium(II)/Isoquinoline Catalyst
10.1002/anie.201704411 · ExternalCitation · doi-reference
Palladium(II)-Initiated Catellani-Type Reactions
10.1002/anie.201813491 · ExternalCitation · doi-reference
Advancing the Logic of Chemical Synthesis: C–H Activation as Strategic and Tactical Disconnections for C–C Bond Construction
10.1002/anie.202011901 · ExternalCitation · doi-reference
Palladium (II)-Catalyzed C–H Activation with Bifunctional Ligands: From Curiosity to Industrialization
10.1002/anie.202400509 · ExternalCitation · doi-reference
Regioisomeric π-Extended Nanographene with Long-Lived Phosphorescence Afterglow
10.1002/anie.202422125 · ExternalCitation · doi-reference
Catellani Reaction: An Enabling Technology for Vicinal Functionalization of Aryl Halides by Palladium(0)/Norbornene Cooperative Catalysis
10.1002/cjoc.202000600 · ExternalCitation · doi-reference
From C4 to C7: Innovative Strategies for Site-Selective Functionalization of Indole C–H Bonds
10.1021/acs.accounts.0c00888 · ExternalCitation · doi-reference
Pd/Norbornene: A Winning Combination for Selective Aromatic Functionalization via C–H Bond Activation
10.1021/acs.accounts.6b00165 · ExternalCitation · doi-reference
From Pd(OAc)2 to Chiral Catalysts: The Discovery and Development of Bifunctional Mono-N-Protected Amino Acid Ligands for Diverse C–H Functionalization Reactions
10.1021/acs.accounts.9b00621 · ExternalCitation · doi-reference
Palladium/Norbornene Cooperative Catalysis
10.1021/acs.chemrev.9b00079 · ExternalCitation · doi-reference
Discovery of Potent and Brain-Penetrant Tau Tubulin Kinase 1 (TTBK1) Inhibitors that Lower Tau Phosphorylation In Vivo
10.1021/acs.jmedchem.1c00382 · ExternalCitation · doi-reference
Design, Synthesis, and Biological Evaluation of Selective PAK4 Degrader for the Treatment of Lung Tumor Metastasis
10.1021/acs.jmedchem.5c00197 · ExternalCitation · doi-reference
Chiral Phosphoric Acid-Catalyzed C6 Functionalization of 2,3-Disubstituted Indoles for Synthesis of Heterotriarylmethanes
10.1021/acs.orglett.0c04002 · ExternalCitation · doi-reference
Palladium(II)-Catalyzed Direct C7-Acyloxylation of Indoles
10.1021/acs.orglett.5c04739 · ExternalCitation · doi-reference
Remote Stereocontrol in the C6-Functionalization of Indoles via Synergistic Ion-Pair Catalysis
10.1021/acscatal.5c00780 · ExternalCitation · doi-reference
Remote C6-Selective Ruthenium-Catalyzed C–H Alkylation of Indole Derivatives via σ-Activation
10.1021/acscatal.7b00038 · ExternalCitation · doi-reference
Beyond C2 and C3: Transition-Metal-Catalyzed C–H Functionalization of Indole
10.1021/acscatal.7b01785 · ExternalCitation · doi-reference
Palladium-Catalyzed meta-C–H Functionalization of Masked Aromatic Aldehydes
10.1021/acscatal.8b01599 · ExternalCitation · doi-reference
Pd(II)-Catalyzed meta-C–H Olefination, Arylation, and Acetoxylation of Indolines Using a U-Shaped Template
10.1021/ja505737x · ExternalCitation · doi-reference
Structurally Modified Norbornenes: A Key Factor to Modulate Reaction Selectivity in the Palladium/Norbornene Cooperative Catalysis
10.1021/jacs.0c09193 · ExternalCitation · doi-reference
Total Synthesis of Verruculogen and Fumitremorgin A Enabled by Ligand-Controlled C–H Borylation
10.1021/jacs.5b07154 · ExternalCitation · doi-reference
Ligand-Enabled Meta-C–H Alkylation and Arylation Using a Modified Norbornene
10.1021/jacs.5b08914 · ExternalCitation · doi-reference
Ligand-Promoted Meta-C–H Arylation of Anilines, Phenols, and Heterocycles
10.1021/jacs.6b04966 · ExternalCitation · doi-reference
Cu-Catalyzed Direct C6-Arylation of Indoles
10.1021/jacs.6b05777 · ExternalCitation · doi-reference
Ligand-Promoted meta-C–H Amination and Alkynylation
10.1021/jacs.6b08942 · ExternalCitation · doi-reference
Ligand Promoted meta-C–H Chlorination of Anilines and Phenols
10.1021/jacs.6b11055 · ExternalCitation · doi-reference
Ligand-Enabled meta-Selective C–H Arylation of Nosyl-Protected Phenethylamines, Benzylamines, and 2-Aryl Anilines
10.1021/jacs.6b11097 · ExternalCitation · doi-reference
Entry to 1,2,3,4-Tetrasubstituted Arenes through Addressing the “Meta Constraint” in the Palladium/Norbornene Catalysis
10.1021/jacs.9b12355 · ExternalCitation · doi-reference
Catalytic C6 Functionalization of 2,3-Disubstituted Indoles by Scandium Triflate
10.1021/jo402511b · ExternalCitation · doi-reference
Electrically driven directional motion of a four-wheeled molecule on a metal surface
10.1038/nature10587 · ExternalCitation · doi-reference
Ligand-enabled meta-C-H activation using a transient mediator
10.1038/nature14214 · ExternalCitation · doi-reference
Complementary site-selectivity in arene functionalization enabled by overcoming the orthoconstraint in palladium/norbornene catalysis
10.1038/s41557-018-0074-z · ExternalCitation · doi-reference
Modular and regioselective synthesis of all-carbon tetrasubstituted olefins enabled by an alkenyl Catellani reaction
10.1038/s41557-019-0358-y · ExternalCitation · doi-reference
Differentiation and functionalization of remote C–H bonds in adjacent positions
10.1038/s41557-020-0424-5 · ExternalCitation · doi-reference
Site-selective C-H functionalization to access the arene backbone of indoles and quinolines
10.1039/d0cs00334d · ExternalCitation · doi-reference
Transition metal-catalyzed C–H functionalizations of indoles
10.1039/d1nj01696b · ExternalCitation · doi-reference
6H-Indolo-[2,3-b]-quinoxaline derivatives as promising bifunctional SHP1 inhibitors
10.1039/d4ob01492h · ExternalCitation · doi-reference
meta-C–H functionalization of phenylethyl and benzylic alcohol derivatives via Pd/NBE relay catalysis
10.1039/d4sc03802a · ExternalCitation · doi-reference
Dispersion-controlled C6-selective C–H borylation of indoles
10.1039/d5cc01554e · ExternalCitation · doi-reference
Regioselective one-step C2-H methylation of free (N-H) indoles enabled by Pd(II)/norbornene cooperative catalysis
10.1039/d5qo00869g · ExternalCitation · doi-reference
Triple cross-electrophile coupling enabled by palladium/norbornene cooperative catalysis
10.1126/sciadv.adu4573 · ExternalCitation · doi-reference
