Research graph
References from Biomimetic Base-Exchange Reaction for Late-Stage Synthesis of Stereodivergent NAADP+ and NAD(P)+ Derivatives. Local targets link to admitted publications; unresolved targets remain external evidence.
NAD+ in aging, metabolism, and neurodegeneration
10.1126/science.aac4854 · 2015 · External reference
NAD+ metabolism: pathophysiologic mechanisms and therapeutic potential
10.1038/s41392-020-00311-7 · 2020 · External reference
The role of NAD+ metabolism and its modulation of mitochondria in aging and disease
10.1038/s44324-025-00067-0 · 2025 · External reference
Cyclic ADP ribose activation of the ryanodine receptor is mediated by calmodulin
10.1038/370307a0 · 1994 · External reference
Regulation of calcium signalling in T lymphocytes by the second messenger cyclic ADP-ribose
10.1038/18024 · 1999 · External reference
NAD+ metabolism and its roles in cellular processes during ageing
10.1038/s41580-020-00313-x · 2021 · External reference
ADP-ribosylation, a multifaceted posttranslational modification involved in the control of cell physiology in health and disease
10.1021/acs.chemrev.7b00122 · 2018 · External reference
Emerging roles of NAD+ and its metabolites in cell signaling
10.1126/scisignal.257mr1 · 2009 · External reference
Substituted Nicotinamide Analogues of Nicotinamide Adenine Dinucleotide
10.1016/s0021-9258(18)67903-7 · 1963 · External reference
Mechanisms of calcium signaling by cyclic ADP-ribose and NAADP
10.1152/physrev.1997.77.4.1133 · 1997 · External reference
NAADP mobilizes calcium from acidic organelles through two-pore channels
10.1038/nature08030 · 2009 · External reference
Cyclic ADP-ribose and nicotinic acid adenine dinucleotide phosphate (NAADP) as messengers for calcium mobilization
10.1074/jbc.r112.349464 · 2012 · External reference
Coordination of agonist-induced Ca2+-signalling patterns by NAADP in pancreatic acinar cells
10.1038/18032 · 1999 · External reference
Calcium Signaling: NAADP Ascends as a New Messenger
10.1016/s0960-9822(03)00120-9 · 2003 · External reference
NAADP: from discovery to mechanism
10.3389/fimmu.2021.703326 · 2021 · External reference
Nicotinic acid adenine dinucleotide phosphate analogues containing substituted nicotinic acid: effect of modification on Ca2+ release
10.1021/jm1007209 · 2010 · External reference
Nicotinic acid adenine dinucleotide phosphate analogues substituted on the nicotinic acid and adenine ribosides. Effects on receptormediated Ca2+ release
10.1021/acs.jmedchem.5b00279 · 2015 · External reference
Engineering Noncanonical Cofactors To Expand Cellular Functions
10.1021/acssynbio.5c00473 · 2025 · External reference
Diazirine-AIOC-NAADP, a Clickable-Photoactive NAADP Analog for Sea Urchin NAADP Binding Proteins
10.1021/acschembio.4c00425 · 2024 · External reference
The synthesis and characterization of a clickable-photoactive NAADP analog active in human cells
10.1016/j.ceca.2019.102060 · 2019 · External reference
Photoaffinity Labeling of Nicotinic Acid Adenine Dinucleotide Phosphate (NAADP) Targets in Mammalian Cells*◆
10.1074/jbc.m111.305813 · 2012 · External reference
An NAD+ analogue enables assembly of structurally diverse artificial photoenzymes for enantiodivergent [2 + 2] cycloadditions
10.1038/s41929-025-01390-x · 2025 · External reference
MASTER-NAADP: a membrane permeable precursor of the Ca2+ mobilizing second messenger NAADP
10.1038/s41467-024-52024-y · 2024 · External reference
Activity of Nicotinic Acid Substituted Nicotinic Acid Adenine Dinucleotide Phosphate (NAADP) Analogs in a Human Cell Line: Difference in Specificity between Human and Sea Urchin NAADP Receptors
10.1016/j.ceca.2013.12.004 · 2014 · External reference
Caged NADP and NAD. Synthesis and Characterization of Functionally Distinct Caged Compounds
10.1021/bi970263e · 1997 · External reference
Synthesis of Caged NAADP
10.1101/pdb.prot076943 · 2014 · External reference
Chemical synthesis of the second messenger nicotinic acid adenine dinucleotide phosphate by total synthesis of nicotinamide adenine dinucleotide phosphate
10.1002/anie.200460054 · 2004 · External reference
Facile chemoenzymatic synthesis of a novel stable mimic of NAD+
10.1039/c8sc03899f · 2018 · External reference
ADP-ribosyl cyclase and CD38 catalyze the synthesis of a calcium-mobilizing metabolite from NADP+
10.1074/jbc.270.51.30327 · 1995 · External reference
Enzymatic synthesis of caged NADP cofactors: aqueous NADP photorelease and optical properties
10.1021/jo9917846 · 2000 · External reference
Cyclic ADP-Ribose via Stereoselective Cyclization of β-NAD+
10.1021/ja00102a055 · 1994 · External reference
Biomimetic α-selective ribosylation enables two-step modular synthesis of biologically important ADP-ribosylated peptides
10.1038/s41467-020-19409-1 · 2020 · External reference
Chemical O-ADP-Ribosylations: Synthesis and Bioconjugation of ADPr-Peptides/Proteins from NAD+
10.1002/ange.202418321 · 2025 · External reference
Enzymatic and Chemical Synthesis for ADP-Ribosylation Using NAD+ as Building Blocks: New Concerns in Reaction Discovery and Design
10.1002/cbic.202500731 · 2026 · External reference
The experimental evidence in support of glycosylation mechanisms at the SN1-SN2 interface
10.1021/acs.chemrev.8b00083 · 2018 · External reference
Ionic liquids based on FeCl3 and FeCl2. Raman scattering and ab initio calculations
10.1021/ic001042r · 2001 · External reference
Chemical O-ADP-Ribosylations: Synthesis and Bioconjugation of ADPr-Peptides/Proteins from NAD+
10.1002/ange.202418321 · ExternalCitation · doi-reference
Chemical synthesis of the second messenger nicotinic acid adenine dinucleotide phosphate by total synthesis of nicotinamide adenine dinucleotide phosphate
10.1002/anie.200460054 · ExternalCitation · doi-reference
Enzymatic and Chemical Synthesis for ADP-Ribosylation Using NAD+ as Building Blocks: New Concerns in Reaction Discovery and Design
10.1002/cbic.202500731 · ExternalCitation · doi-reference
Activity of Nicotinic Acid Substituted Nicotinic Acid Adenine Dinucleotide Phosphate (NAADP) Analogs in a Human Cell Line: Difference in Specificity between Human and Sea Urchin NAADP Receptors
10.1016/j.ceca.2013.12.004 · ExternalCitation · doi-reference
The synthesis and characterization of a clickable-photoactive NAADP analog active in human cells
10.1016/j.ceca.2019.102060 · ExternalCitation · doi-reference
Substituted Nicotinamide Analogues of Nicotinamide Adenine Dinucleotide
10.1016/s0021-9258(18)67903-7 · ExternalCitation · doi-reference
Calcium Signaling: NAADP Ascends as a New Messenger
10.1016/s0960-9822(03)00120-9 · ExternalCitation · doi-reference
ADP-ribosylation, a multifaceted posttranslational modification involved in the control of cell physiology in health and disease
10.1021/acs.chemrev.7b00122 · ExternalCitation · doi-reference
The experimental evidence in support of glycosylation mechanisms at the SN1-SN2 interface
10.1021/acs.chemrev.8b00083 · ExternalCitation · doi-reference
Nicotinic acid adenine dinucleotide phosphate analogues substituted on the nicotinic acid and adenine ribosides. Effects on receptormediated Ca2+ release
10.1021/acs.jmedchem.5b00279 · ExternalCitation · doi-reference
Diazirine-AIOC-NAADP, a Clickable-Photoactive NAADP Analog for Sea Urchin NAADP Binding Proteins
10.1021/acschembio.4c00425 · ExternalCitation · doi-reference
Engineering Noncanonical Cofactors To Expand Cellular Functions
10.1021/acssynbio.5c00473 · ExternalCitation · doi-reference
Caged NADP and NAD. Synthesis and Characterization of Functionally Distinct Caged Compounds
10.1021/bi970263e · ExternalCitation · doi-reference
Ionic liquids based on FeCl3 and FeCl2. Raman scattering and ab initio calculations
10.1021/ic001042r · ExternalCitation · doi-reference
Cyclic ADP-Ribose via Stereoselective Cyclization of β-NAD+
10.1021/ja00102a055 · ExternalCitation · doi-reference
Nicotinic acid adenine dinucleotide phosphate analogues containing substituted nicotinic acid: effect of modification on Ca2+ release
10.1021/jm1007209 · ExternalCitation · doi-reference
Enzymatic synthesis of caged NADP cofactors: aqueous NADP photorelease and optical properties
10.1021/jo9917846 · ExternalCitation · doi-reference
Regulation of calcium signalling in T lymphocytes by the second messenger cyclic ADP-ribose
10.1038/18024 · ExternalCitation · doi-reference
Coordination of agonist-induced Ca2+-signalling patterns by NAADP in pancreatic acinar cells
10.1038/18032 · ExternalCitation · doi-reference
Cyclic ADP ribose activation of the ryanodine receptor is mediated by calmodulin
10.1038/370307a0 · ExternalCitation · doi-reference
NAADP mobilizes calcium from acidic organelles through two-pore channels
10.1038/nature08030 · ExternalCitation · doi-reference
NAD+ metabolism: pathophysiologic mechanisms and therapeutic potential
10.1038/s41392-020-00311-7 · ExternalCitation · doi-reference
Biomimetic α-selective ribosylation enables two-step modular synthesis of biologically important ADP-ribosylated peptides
10.1038/s41467-020-19409-1 · ExternalCitation · doi-reference
MASTER-NAADP: a membrane permeable precursor of the Ca2+ mobilizing second messenger NAADP
10.1038/s41467-024-52024-y · ExternalCitation · doi-reference
NAD+ metabolism and its roles in cellular processes during ageing
10.1038/s41580-020-00313-x · ExternalCitation · doi-reference
An NAD+ analogue enables assembly of structurally diverse artificial photoenzymes for enantiodivergent [2 + 2] cycloadditions
10.1038/s41929-025-01390-x · ExternalCitation · doi-reference
The role of NAD+ metabolism and its modulation of mitochondria in aging and disease
10.1038/s44324-025-00067-0 · ExternalCitation · doi-reference
Facile chemoenzymatic synthesis of a novel stable mimic of NAD+
10.1039/c8sc03899f · ExternalCitation · doi-reference
ADP-ribosyl cyclase and CD38 catalyze the synthesis of a calcium-mobilizing metabolite from NADP+
10.1074/jbc.270.51.30327 · ExternalCitation · doi-reference
Photoaffinity Labeling of Nicotinic Acid Adenine Dinucleotide Phosphate (NAADP) Targets in Mammalian Cells*◆
10.1074/jbc.m111.305813 · ExternalCitation · doi-reference
Cyclic ADP-ribose and nicotinic acid adenine dinucleotide phosphate (NAADP) as messengers for calcium mobilization
10.1074/jbc.r112.349464 · ExternalCitation · doi-reference
Synthesis of Caged NAADP
10.1101/pdb.prot076943 · ExternalCitation · doi-reference
NAD+ in aging, metabolism, and neurodegeneration
10.1126/science.aac4854 · ExternalCitation · doi-reference
Emerging roles of NAD+ and its metabolites in cell signaling
10.1126/scisignal.257mr1 · ExternalCitation · doi-reference
Mechanisms of calcium signaling by cyclic ADP-ribose and NAADP
10.1152/physrev.1997.77.4.1133 · ExternalCitation · doi-reference
NAADP: from discovery to mechanism
10.3389/fimmu.2021.703326 · ExternalCitation · doi-reference