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References from Correlating the C-5 Induction Effect on Uracil-Based Nucleoside Lipid Nanoparticles for Enhanced Redox-Mediated Therapeutic Efficacy in Hepatocellular Carcinoma. Local targets link to admitted publications; unresolved targets remain external evidence.
Mechanisms of doxorubicin resistance in hepatocellular carcinoma
10.2217/hep.15.41 · 2016 · External reference
TOP2A inhibition reverses drug resistance of hepatocellular carcinoma to regorafenib
2022 · External reference
Lipid-Based Nanoparticles for Drug/Gene Delivery: An Overview of the Production Techniques and Difficulties Encountered in Their Industrial Development
10.1021/acsmaterialsau.3c00032 · 2023 · External reference
Mechanism of pH-sensitive Amphiphilic Endosomal Escape of Ionizable Lipid Nanoparticles for Cytosolic Nucleic Acid Delivery
10.1007/s11095-025-03890-8 · 2025 · External reference
Development of novel pyrimidine nucleoside analogs as potential anticancer agents: Synthesis, characterization, and In-vitro evaluation against pancreatic cancer
10.1016/j.ejps.2024.106754 · 2024 · External reference
Improving nucleoside analogs via lipid conjugation: Is fatter any better?
10.1016/j.critrevonc.2016.01.015 · 2016 · External reference
Tetrahydropyrimidine Ionizable Lipids for Efficient mRNA Delivery
10.1021/acsnano.4c10154 · 2024 · External reference
Comprehensive analysis of lipid nanoparticle formulation and preparation for RNA delivery
10.1016/j.ijpx.2024.100283 · 2024 · External reference
Influence of Hydrophobicity in the Hydrophilic Region of Cationic Lipids on Enhancing Nucleic Acid Delivery and Gene Editing
10.1021/acsabm.1c01226 · 2022 · External reference
Diverse lipid conjugates for functional extra-hepatic siRNA delivery in vivo
10.1093/nar/gky1239 · 2019 · External reference
Tannic acid-based nanogel as an efficient anti-inflammatory agent
10.1039/c9bm01384a · 2020 · External reference
Nanoparticle-Mediated mRNA Delivery to Triple-Negative Breast Cancer (TNBC) Patient-Derived Xenograft (PDX) Tumors
10.1021/acsptsci.4c00597 · 2025 · External reference
Doxorubicin-conjugated siRNA lipid nanoparticles for combination cancer therapy
10.1016/j.apsb.2022.07.011 · 2023 · External reference
Codelivery of doxorubicin and curcumin with lipid nanoparticles results in improved efficacy of chemotherapy in liver cancer
10.2147/ijn.s73322 · 2015 · External reference
Delivery of mitochondriotropic doxorubicin derivatives using self-assembling hyaluronic acid nanocarriers in doxorubicin-resistant breast cancer
10.1038/aps.2018.9 · 2018 · External reference
Synergistic Effect of Doxorubicin and Blue Light Irradiation on the Antitumor Treatment of HepG2 Cells in Liver Cancer
10.3390/molecules29143360 · 2024 · External reference
Apoptosis induction in human hepatoma cell line HepG2 cells by trans- Anethole via activation of mitochondria-mediated apoptotic pathways
10.1016/j.biopha.2023.115236 · 2023 · External reference
Biosynthesis and characterisation of solid lipid nanoparticles and investigation of toxicity against breast cancer cell line
10.1049/nbt2.12062 · 2021 · External reference
FZD7-Targeted Nanoparticles to Enhance Doxorubicin Treatment of Triple-Negative Breast Cancer
10.1021/acsomega.3c10275 · 2024 · External reference
Albumin nanoparticles-mediated doxorubicin delivery enhances the anti-tumor efficiency in ovarian cancer cells through controlled release
10.1007/s00210-024-03730-3 · 2025 · External reference
Breaking a Dogma: High-Throughput Live-Cell Imaging in Real-Time with Hoechst 33342
10.1002/adhm.202300230 · 2023 · External reference
Hypoxia-inducible factor-1-dependent regulation of the multidrug resistance (MDR1) gene
2002 · External reference
Psoralen-loaded lipid-polymer hybrid nanoparticles enhance doxorubicin efficacy in multidrug-resistant HepG2 cells
10.2147/ijn.s189924 · 2019 · External reference
Supplementation with conjugated linoeic acid decreases pig back fat deposition by inducing adipocyte apoptosis
10.1186/1746-6148-10-141 · 2014 · External reference
MDR1 gene expression: its effect on drug resistance to doxorubicin in human hepatocellular carcinoma cell lines
10.1093/jnci/86.9.700 · 1994 · External reference
mRNA Expression of Bax, Bcl-2, p53, Cathepsin B, Caspase-3 and Caspase-9 in the HepG2 Cell Line Following Induction by a Novel Monoclonal Ab Hep88 mAb: Cross-Talk for Paraptosis and Apoptosis
10.7314/apjcp.2016.17.2.703 · 2016 · External reference
Doxorubicin/Nucleophosmin Binding Protein-Conjugated Nanoparticle Enhances Anti-leukemia Activity in Acute Lymphoblastic Leukemia Cells in vitro and in vivo
10.3389/fphar.2021.607755 · 2021 · External reference
Liver-Specific Biocompatible Lipid Nanoparticle-Enabled mRNA Therapy for Haemophilia B
10.1002/adhm.202503248 · 2026 · External reference
Optimized 5-Fluorouridine Prodrug for Co-Loading with Doxorubicin in Clinically Relevant Liposomes
10.3390/pharmaceutics13010107 · 2021 · External reference
Resolving a Sequential Post-Transition-State Bifurcation Mechanism in the Dimerization of 2,3-Diazacyclopentadienone
10.1021/acs.joc.5c02440 · 2026 · External reference
Molecular dynamics simulations of doxorubicin in sphingomyelin-based lipid membranes
10.1016/j.bbamem.2021.183763 · 2022 · External reference
Development of Tris-(triazolyl)-s–triazine Linker-Based Cationic Amphiphiles: Stability and Gene Delivery Applications
10.1002/slct.202302649 · 2023 · External reference
Enhanced Anticancer Activity of 5'-DFUR-PCL-MPEG Polymeric Prodrug Micelles Encapsulating Chemotherapeutic Drugs
10.3390/nano8121041 · 2018 · External reference
Unraveling Ambimodal Periselectivity in Pentafulvene–Radialene Cycloadditions: Interplay of Geometry, Charge Delocalisation, and Reaction Dynamics
10.1021/acs.jpca.5c06928 · 2026 · External reference
Cytotoxicity of chemotherapeutic agents in glyceraldehyde-3-phosphate dehydrogenase-depleted human lung carcinoma A549 cells with the accelerated senescence phenotype
10.1097/cad.0b013e32835e3378 · 2013 · External reference
EP1 activation inhibits doxorubicin-cardiomyocyte ferroptosis via Nrf2
10.1016/j.redox.2023.102825 · 2023 · External reference
Mitochondria-Targeted Microneedles Reverse Doxorubicin Resistance via Apoptosis-Ferroptosis Synergy
10.1021/acsnano.5c06302 · 2025 · External reference
Apigenin ameliorates doxorubicin-induced renal injury via inhibition of oxidative stress and inflammation
10.1016/j.biopha.2021.111308 · 2021 · External reference
A doxorubicin delivery platform using engineered natural membrane vesicle exosomes for targeted tumor therapy
10.1016/j.biomaterials.2013.11.083 · 2014 · External reference
Mechanisms of Apoptotic Cell Death by Stainless Steel Nanoparticle Through Reactive Oxygen Species and Caspase-3 Activities on Human Liver Cells
10.3389/fmolb.2021.729590 · 2021 · External reference
Base-modified factor VIII mRNA delivery with galactosylated lipid nanoparticles as a protein replacement therapy for haemophilia A
10.1039/d4bm00909f · 2024 · External reference
Doxorubicin sensitizes human tumor cells to NK cell- and T-cell-mediated killing by augmented TRAIL receptor signaling
10.1002/ijc.28163 · 2013 · External reference
Doxorubicin promotes NK cell dysfunction and induces acute liver injury through kynurenine-AhR axis
10.1016/j.intimp.2025.114489 · 2025 · External reference
Aegeline improves doxorubicin-induced liver toxicity by modulating oxidative stress and Bax/Bcl2/caspase/NF-κB signaling
10.1038/s41598-025-09675-8 · 2025 · External reference
Folate-mediated mitochondrial targeting with doxorubicin-polyrotaxane nanoparticles overcomes multidrug resistance
10.18632/oncotarget.3090 · 2015 · External reference
Nutraceutical Synergy: Unraveling the Protective Effects of Methyl Gallate and Chia Seed Oil in Doxorubicin-induced Hepatic Injury and Bax/Bcl2 Imbalance
10.2174/0113816128366802250413160625 · 2025 · External reference