Research graph
References from Aloe-Emodin Interaction Study with Human Telomeric G-Quadruplex DNA under K+ and Na+ Conditions. Local targets link to admitted publications; unresolved targets remain external evidence.
Targeting G-quadruplexes in gene promoters: a novel anticancer strategy?
10.1038/nrd3428 · 2011 · External reference
Telomerase activity in normal and malignant mammalian tissues: feasibility of telomerase as a target for cancer chemotherapy
10.1038/bjc.1997.90 · 1997 · External reference
NMR-based model of a telomerase-inhibiting compound bound to G-quadruplex DNA
10.1021/bi981330n · 1998 · External reference
G-quadruplex structures: in vivo evidence and function
10.1016/j.tcb.2009.05.00 · 2009 · External reference
Advances in the molecular design of potential anticancer agents via targeting of human telomeric DNA
10.1039/c4cc00611a · 2014 · External reference
Circular dichroism and guanine quadruplexes
10.1016/j.ymeth.2012.03.011 · 2012 · External reference
Molecular recognition of telomere DNA sequence by 2, 6 anthraquinone derivatives leads to thermal stabilization and induces apoptosis in cancer cells
10.1016/j.ijbiomac.2022.08.156 · 2022 · External reference
Intercalation of a heterocyclic ligand between quartets in a G-rich tetrahelical structure
10.1002/chem.201904923 · 2020 · External reference
Binding of anticancer drug daunomycin to parallel G-quadruplex DNA [d-(TTGGGGT)]4 leads to thermal stabilization: A multispectroscopic investigation
10.1016/j.ijbiomac.2018.09.154 · 2018 · External reference
Molecular recognition of the hybrid-2 human telomeric G-quadruplex by epiberberine: insights into conversion of telomeric G-quadruplex structures
10.1002/ange.201804667 · 2018 · External reference
Interaction of anthraquinone anti-cancer drugs with DNA: Experimental and computational quantum chemical study
10.1016/j.molstruc.2016.08.007 · 2017 · External reference
Aloe vera: Nature's silent healer
2003 · External reference
Interaction of aloe active compounds with calf thymus DNA
10.1002/jmr.2786 · 2019 · External reference
The antiproliferative activity of aloe-emodin is through p53-dependent and p21-dependent apoptotic pathway in human hepatoma cell lines
10.1016/s0024-3205(02)01900-8 · 2002 · External reference
Aloe emodin induces apoptosis in ER+-breast cancer cells; MCF-7 through IGF-1R signalling pathway
10.17576/jsm-2015-4408-09 · 2015 · External reference
Release of nucleophosmin from the nucleus: Involvement in aloe-emodin-induced human lung non-small carcinoma cell apoptosis
10.1002/ijc.20676 · 2005 · External reference
Aloe-emodin enhances tamoxifen cytotoxicity by suppressing Ras/ERK and PI3K/mTOR in breast cancer cells
10.1142/s0192415x17500215 · 2017 · External reference
Anticancer effect of aloe-emodin on cervical cancer cells involves G2/M arrest and induction of differentiation
10.1111/j.1745-7254.2007.00707.x · 2007 · External reference
Advancements in utilizing natural compounds for modulating autophagy in liver cancer: Molecular mechanisms and therapeutic targets
10.3390/cells13141186 · 2024 · External reference
Aloe-emodin overcomes anti-cancer drug resistance to temozolomide and prevents colony formation and migration in primary human glioblastoma cell lines NULU and ZAR
10.3390/molecules28166024 · 2023 · External reference
Effects of aloe-emodin and emodin on proliferation of the MKN45 human gastric cancer cell line
10.7314/apjcp.2015.16.9.3887 · 2015 · External reference
The antiproliferative potential of isolated emodin and aloe-emodin from Rheum ribes on different cancer cell lines
10.46309/biodicon.2020.753046 · 2020 · External reference
Anti-cancer effects of aloe-emodin: a systematic review
2017 · External reference
A review on the relationship between Aloe vera components and their biologic effects
10.1016/s1543-1150(03)00005-x · 2003 · External reference
Biophysical, Anticancer, Antibacterial and Antiviral Profiles of Aloe-emodin: A Mini-Review
2021 · External reference
Emodin and aloe-emodin suppress breast cancer cell proliferation through ERα inhibition
10.1155/2013/376123 · 2013 · External reference
Advances in understanding the role of aloe emodin and targeted drug delivery systems in cancer
10.1155/2022/7928200 · 2022 · External reference
Aloe emodin inhibits telomerase activity in breast cancer cells: transcriptional and enzymological mechanism
10.1007/s43440-020-00062-w · 2020 · External reference
Spectroscopic studies on the interaction of aloe-emodin and DNA
2011 · External reference
Photochemistry and Phototoxicity of Aloe Emodin
10.1562/0031-8655(2002)0750346papoae2.0.co2 · 2002 · External reference
Interaction of anthraquinones of Cassia occidentalis seeds with DNA and Glutathione
10.1016/j.toxrep.2017.12.024 · 2018 · External reference
Binding studies of aloe-active compounds with G-quadruplex sequences
10.1021/acsomega.1c02207 · 2021 · External reference
Investigation of the interaction between Aloe vera anthraquinone metabolites and c-myc and C-kit G-quadruplex DNA structures
10.3390/ijms232416018 · 2022 · External reference
Targeting aloe active compounds to c-KIT promoter G-quadruplex and comparative study of their anti-proliferative property
10.1080/07391102.2022.2145370 · 2023 · External reference
Gold nanorod-based FRET assay for selection of G-quadruplex-binding ligands
10.1007/s13404-011-0022-9 · 2011 · External reference
Identifying G-quadruplex-binding ligands using DNA-functionalized gold nanoparticles
10.1039/c2an16051j · 2012 · External reference
High-throughout identification of telomere-binding ligands based on photo-induced electron transfer
10.1039/c5ra25612g · 2016 · External reference
High-throughput identification of telomere-binding ligands based on the fluorescence regulation of DNA-copper nanoparticles
10.1016/j.bios.2016.09.055 · 2017 · External reference
Structure of the intramolecular human telomeric G-quadruplex in potassium solution: a novel adenine triple formation
10.1093/nar/gkm009 · 2007 · External reference
Structure of the Hybrid-2 type intramolecular human telomeric G-quadruplex in K+ solution: insights into structure polymorphism of the human telomeric sequence
10.1093/nar/gkm522 · 2007 · External reference
Solution structure of the human telomeric repeat d [AG3(T2AG3)3] G-tetraplex
10.1016/0969-2126(93)90015-9 · 1993 · External reference
A 4:1 stoichiometric binding and stabilization of mitoxantrone-parallel stranded G-quadruplex complex established by spectroscopy techniques
10.1016/j.jphotobiol.2016.06.019 · 2016 · External reference
Spectroscopic and Molecular Docking Studies on the Interaction of Aloe-emodin with GC and AT specific DNA Oligonucleotides
2021 · External reference
Binding of the alkaloid coralyne to parallel G-quadruplex DNA [d-(TTGGGGT)]4 studied by multi-spectroscopic techniques
10.1016/j.bpc.2016.09.006 · 2016 · External reference
Molecular recognition of parallel DNA quadruplex d (TTAGGGT)4 by mitoxantrone: binding with 1:2 stoichiometry leading to thermal stabilization and telomerase inhibition
10.1002/cbic.201500588 · 2016 · External reference
Molecular recognition of 3+1 hybrid human telomeric G-quadruplex DNA d-[AGGG(TTAGGG)3] by anticancer drugs epirubicin and adriamycin leads to thermal stabilization
10.1016/j.ijbiomac.2019.08.109 · 2019 · External reference
Spectroscopy evidence of interaction of 1, 5 disubstituted piperidino-amido anthraquinone derivative with human telomeric G-quadruplex DNA: basis of anticancer action
10.1016/j.rechem.2023.101148 · 2023 · External reference
10.1007/978-3-319-21756-7_7
10.1007/978-3-319-21756-7_7 · 2016 · External reference
Effect of ions on the polymorphism, effective charge, and stability of human telomeric DNA Photon correlation spectroscopy and circular dichroism studies
10.1021/jp045274d · 2005 · External reference
Theoretical study on photophysical and photosensitive properties of aloe emodin
10.1016/j.theochem.2005.11.005 · 2006 · External reference
Mixed-ligand complexes of ruthenium (II): factors governing binding to DNA
10.1021/ja00190a046 · 1989 · External reference
Affinity of the anthracycline antitumor drugs Doxorubicin and Sabarubicin for human telomeric G-quadruplex structures
10.1039/c0cp00898b · 2010 · External reference
Quenching of fluorescence by oxygen. Probe for structural fluctuations in macromolecules
10.1021/bi00745a020 · 1973 · External reference
Biophysical characterization of the human telomeric (TTAGGG)4 repeat in a potassium solution
10.1021/bi602511p · 2007 · External reference
Circular dichroism of quadruplex DNAs: applications to structure, cation effects and ligand binding
10.1016/j.ymeth.2007.02.009 · 2007 · External reference
Aryl ethynyl anthraquinones: a useful platform for targeting telomeric G-quadruplex structures
10.1039/c4ob00220b · 2014 · External reference
Diarylethynyl amides that recognize the parallel conformation of genomic promoter DNA G-quadruplexes
10.1021/ja8046552 · 2008 · External reference
Dual recognition of the human telomeric G-quadruplex by a neomycin–anthraquinone conjugate
10.1039/c3cc42721h · 2013 · External reference
Structure-specific recognition of quadruplex DNA by organic cations: influence of shape, substituents and charge
10.1016/j.bpc.2006.06.006 · 2007 · External reference
Binding modes of a core-extended metalloporphyrin to human telomeric DNA G-quadruplexes
10.1039/c4ob02097a · 2015 · External reference
Design, synthesis and biological evaluation of new substituted diquinolinyl-pyridine ligands as anticancer agents by targeting G-Quadruplex
10.3390/molecules23010081 · 2017 · External reference
Ligand-Induced Conformational Changes with Cation Ejection upon Binding to Human Telomeric DNA G-Quadruplexes
10.1021/ja5099403 · 2015 · External reference
Kinetic evidence for interaction of TMPyP4 with two different G-quadruplex conformations of human telomeric DNA
10.1016/j.bbagen.2017.10.020 · 2018 · External reference
Telomere targeting with a novel G-quadruplex-interactive ligand BRACO-19 induces T-loop disassembly and telomerase displacement in human glioblastoma cells
10.18632/oncotarget.7483 · 2016 · External reference
In-vitro antitumor activity of mitomycin C derivative (RM-49) and new anticancer antibiotics (FK973) against lung cancer cell lines determined by tetrazolium dye (MTT) assay
10.1007/bf00273419 · 1988 · External reference
In-vitro cytotoxicity assays: comparison of LDH, neutral red, MTT and protein assay in hepatoma cell lines following exposure to cadmium chloride
10.1016/j.toxlet.2005.07.001 · 2006 · External reference
