Research graph
References from Dexamethasone Sustained-Release Microspheres with Single-Phase Zero-Order Release Behavior for Intra-Articular Injection: Effects of Polymer Blending and Release Promoter Incorporation. Local targets link to admitted publications; unresolved targets remain external evidence.
Gender Differences in the Combined Effects of Cardiovascular Disease and Osteoarthritis on Progression to Functional Impairment in Older Mexican Americans
10.1093/gerona/glw014 · 2016 · External reference
Global, regional, and national burden of osteoarthritis, 1990-2020 and projections to 2050: a systematic analysis for the Global Burden of Disease Study 2021
10.1016/s2665-9913(23)00163-7 · 2023 · External reference
Shear-thinning hyaluronan-based fluid hydrogels to modulate viscoelastic properties of osteoarthritis synovial fluids
10.1039/c9bm00298g · 2019 · External reference
Osteoarthritis Pathology, Diagnosis, and Treatment Options
10.1016/j.mcna.2019.10.007 · 2020 · External reference
Diagnosis and Treatment of Hip and Knee Osteoarthritis A Review
10.1001/jama.2020.22171 · 2021 · External reference
Inflammation in osteoarthritis: the latest progress and ongoing challenges
10.1097/bor.0000000000000923 · 2023 · External reference
Analysis of disease burden of osteoarthritis in China from 1990 to 2021 and projections for 2022–2044
10.1016/j.ocarto.2026.100859 · 1990 · External reference
Temporal trends and sociodemographic disparities in osteoarthritis prevalence among U.S. adults
10.1016/j.tmed.2026.100017 · 2026 · External reference
OARSI guidelines for the non-surgical management of knee, hip, and polyarticular osteoarthritis
10.1016/j.joca.2019.06.011 · 2019 · External reference
Safety of Opioids in Osteoarthritis: Outcomes of a Systematic Review and Meta-Analysis
10.1007/s40266-019-00666-9 · 2019 · External reference
Glucocorticoid signaling and osteoarthritis
10.1016/j.mce.2018.11.001 · 2019 · External reference
Efficacy and safety of intraarticular hyaluronic acid and corticosteroid for knee osteoarthritis: A meta-analysis
10.1016/j.ijsu.2017.01.087 · 2017 · External reference
Critical appraisal of intra-articular glucocorticoid injections for symptomatic osteoarthritis of the knee
10.1016/j.joca.2020.09.001 · 2021 · External reference
Dexamethasone: Chondroprotective Corticosteroid or Catabolic Killer?
10.22203/ecm.v038a17 · 2019 · External reference
Intra-articular dexamethasone to inhibit the development of post-traumatic osteoarthritis
10.1002/jor.23295 · 2017 · External reference
How PLGA Microspheres are Emerging as a Key Drug Delivery System
10.2147/ijn.s600160 · 2026 · External reference
A long-acting formulation of a polypeptide drug exenatide in treatment of diabetes using an injectable block copolymer hydrogel
10.1016/j.biomaterials.2013.01.013 · 2013 · External reference
PEG-based thermosensitive and biodegradable hydrogels
10.1016/j.actbio.2021.04.009 · 2021 · External reference
Integrated implantable device for long-term glucose monitoring
10.1016/0956-5663(95)96894-5 · 1995 · External reference
PLGA Implants for Controlled Drug Delivery and Regenerative Medicine: Advances, Challenges, and Clinical Potential
10.3390/ph18050631 · 2025 · External reference
Thermal stability of exenatide encapsulated in stratified dissolving microneedles during storage
10.1016/j.ijpharm.2023.122863 · 2023 · External reference
Microneedles: A smart approach and increasing potential for transdermal drug delivery system
10.1016/j.biopha.2018.10.078 · 2019 · External reference
PLGA/PLA-Based Long-Acting Injectable Depot Microspheres in Clinical Use: Production and Characterization Overview for Protein/Peptide Delivery
10.3390/ijms22168884 · 2021 · External reference
A review of recent research and development on GLP-1 receptor agonists-sustained-release microspheres
10.1039/d3tb02207b · 2023 · External reference
Long-acting PLGA microspheres: Advances in excipient and product analysis toward improved product understanding
10.1016/j.addr.2023.114857 · 2023 · External reference
Microstructure Formation and Characterization of Long-Acting Injectable Microspheres: The Gateway to Fully Controlled Drug Release Pattern
10.2147/ijn.s445269 · 2024 · External reference
Release mechanisms of PLGA-based drug delivery systems: A review
10.1016/j.ijpx.2025.100440 · 2025 · External reference
Sustained-Release Intra-Articular Drug Delivery: PLGA Systems in Clinical Context and Evolving Strategies
10.3390/pharmaceutics17101350 · 2025 · External reference
Ultralong-Acting PLGA Microspheres Engineered to Sustain Release across the Entire Bone-Regeneration Timeline
10.1021/acsbiomaterials.6c00161 · 2026 · External reference
Functionalizing PLGA and PLGA Derivatives for Drug Delivery and Tissue Regeneration Applications
10.1002/adhm.201701035 · 2018 · External reference
In vitro performance of composition-equivalent PLGA microspheres encapsulating exenatide acetate by solvent evaporation
10.1016/j.ijpharm.2023.123213 · 2023 · External reference
The Effect of Polymer Blends on the In Vitro Release/Degradation and Pharmacokinetics of Moxidectin-Loaded PLGA Microspheres
10.3390/ijms241914729 · 2023 · External reference
Mechanistic evaluation of the initial burst release of leuprolide from spray-dried PLGA microspheres
10.1016/j.jconrel.2023.06.016 · 2023 · External reference
New Insights on the Burst Release Kinetics of Spray-Dried PLGA Microspheres
10.1021/acs.molpharmaceut.4c00686 · 2024 · External reference
Exenatide-loaded inside-porous poly(lactic-co-glycolic acid) microspheres as a long-acting drug delivery system with improved release characteristics
10.1080/10717544.2020.1850919 · 2020 · External reference
Injectable controlled release depots for large molecules
10.1016/j.jconrel.2014.05.057 · 2014 · External reference
PLGA microsphere/PVA hydrogel coatings suppress the foreign body reaction for 6 months
10.1016/j.jconrel.2018.09.021 · 2018 · External reference
Degradable Controlled-Release Polymers and Polymeric Nanoparticles: Mechanisms of Controlling Drug Release
10.1021/acs.chemrev.5b00346 · 2016 · External reference
Modification of Three-Phase Drug Release Mode of Octreotide PLGA Microspheres by Microsphere-Gel Composite System
10.1208/s12249-019-1438-4 · 2019 · External reference
Block-Polymer-Restricted Sub-nanometer Pt Nanoclusters Nanozyme-Enhanced Immunoassay for Monitoring of Cardiac Troponin I
10.1021/acs.analchem.3c03249 · 2023 · External reference
D-Band-Center-Engineered Platinum-Based Nanozyme for Personalized Pharmacovigilance
10.1002/anie.202414625 · 2025 · External reference
Three dimensional distribution of surfactant in microspheres revealed by synchrotron radiation X-ray microcomputed tomography
10.1016/j.ajps.2017.02.001 · 2017 · External reference
Surfactant Mediated Accelerated and Discriminatory In Vitro Drug Release Method for PLGA Nanoparticles of Poorly Water-Soluble Drug
10.3390/ph15121489 · 2022 · External reference
Design of Controlled Release PLGA Microspheres for Hydrophobic Fenretinide
10.1021/acs.molpharmaceut.5b00961 · 2016 · External reference
Self-Assembled PLGA-Pluronic F127 Microsphere for Sustained Drug Release for Osteoarthritis
10.3390/ph17040471 · 2024 · External reference
Pore change during degradation of octreotide acetate-loaded PLGA microspheres: The effect of polymer blends
10.1016/j.ejps.2019.104990 · 2019 · External reference
The effect of polymer blends on initial release regulation and in vitro-in vivo relationship of peptides loaded PLGA-Hydrogel Microspheres
10.1016/j.ijpharm.2020.119964 · 2020 · External reference
Semaglutide sustained-release microspheres with single-phase zero-order release behavior: Effects of polymer blending and surfactants
10.1016/j.jddst.2025.106793 · 2025 · External reference
The Modified Exenatide Microspheres: PLGA-PEG-PLGA Gel and Zinc-Exenatide Complex Synergistically Reduce Burst Release and Shorten Platform Stage
10.1208/s12249-023-02705-6 · 2023 · External reference
Smartphone-Integrated Device Based on d-Band Engineered PtNiFe Nanozymes for on-Site Testing of Perfluorinated Substances
10.1021/acs.analchem.5c05915 · 2025 · External reference
Two-Dimensional Dissipative Paper-Based Immunoassay with Oxygen Vacancy-Enriched CeO2 Nanozymes for Portable Cancer Screening
10.1021/acs.analchem.5c03445 · 2025 · External reference
Crystal Facet Engineering Modulated Electron Transfer Mechanisms: A Self-Powered Photoelectrochemical Sensing Platform for Noninvasive Detection of Uric Acid
10.1021/acs.analchem.5c01345 · 2025 · External reference
Tailored Metal-Organic Framework-Based Nanozymes for Enhanced Enzyme-Like Catalysis
10.1002/anie.202420200 · 2025 · External reference
The Monoiodoacetate Model of Osteoarthritis Pain in the Mouse
10.3791/53746 · 2016 · External reference
Evaluating Knee Osteoarthritis Induction Methods in Small Translational Animal Models from 1970-2025: A Comprehensive Systematic Review
10.22038/abjs.2025.89905.4077 · 2026 · External reference
Fundamentals of osteoarthritis: Inflammatory mediators in osteoarthritis
10.1016/j.joca.2023.06.005 · 2023 · External reference
Refining surgical models of osteoarthritis in mice and rats alters pain phenotype but not joint pathology
10.1371/journal.pone.0239663 · 2020 · External reference
Amniotic Epithelial Stem Cells Counteract Acidic Degradation By-Products of Electrospun PLGA Scaffold by Improving Their Immunomodulatory Profile In Vitro
10.3390/cells10113221 · 2021 · External reference
Simultaneous co-delivery of neuroprotective drugs from multi-loaded PLGA microspheres for the treatment of glaucoma
10.1016/j.jconrel.2019.01.012 · 2019 · External reference
Ski ameliorates synovial cell inflammation in monosodium iodoacetate-induced knee osteoarthritis
10.1016/j.heliyon.2024.e24471 · 2024 · External reference
Synergistic anti-inflammatory effect of cascade nanozymes for neural recovery in ischemic stroke
10.1016/j.cclet.2025.110956 · 2026 · External reference
TNF-α increases the expression of inflammatory factors in synovial fibroblasts by inhibiting the PI3K/AKT pathway in a rat model of monosodium iodoacetate-induced osteoarthritis
10.3892/etm.2018.6770 · 2018 · External reference
Bioactive Ceria Nanoenzymes Target Mitochondria in Reperfusion Injury to Treat Ischemic Stroke
10.1021/acsnano.3c10982 · 2024 · External reference
Magnetic Field Driven Ceria Nanosystems for Mitochondria Targeted Therapy of Ischemic Stroke
10.1002/adfm.202423291 · 2025 · External reference
Ligand-Triggered Topology Switching Converts Transient Recognition into Durable Nanofibrillar Anchoring
10.1021/jacs.6c06778 · 2026 · External reference
An endosymbiotic system based on ATP-expressing bacteria and macrophages for cancer immunotherapy
10.1016/j.celbio.2026.100383 · 2026 · External reference
Monosodium iodoacetate-induced monoarthritis develops differently in knee versus ankle joint in rats
10.1016/j.ynpai.2019.100036 · 2019 · External reference
Assessment of the Impact of Physical Activity on the Musculoskeletal System in Early Degenerative Knee Joint Lesions in an Animal Model
10.3390/ijms24043540 · 2023 · External reference
Foreign body reaction to biomaterials
10.1016/j.smim.2007.11.004 · 2008 · External reference
Electrospun acid-neutralizing fibers for the amelioration of inflammatory response
10.1016/j.actbio.2019.08.014 · 2019 · External reference
Intra-articular delivery of tetramethylpyrazine microspheres with enhanced articular cavity retention for treating osteoarthritis
10.1016/j.ajps.2017.12.007 · 2018 · External reference
