Research graph
References from Manganese-Doped Fluorinated Zeolitic Imidazolate Framework-90 for Activatable 1H/19F MRI and Metalloimmunotherapy of Hepatocellular Carcinoma. Local targets link to admitted publications; unresolved targets remain external evidence.
The Lancet Commission on addressing the global hepatocellular carcinoma burden: comprehensive strategies from prevention to treatment
10.1016/s0140-6736(25)01042-6 · 2025 · External reference
A global view of hepatocellular carcinoma: trends, risk, prevention and management
10.1038/s41575-019-0186-y · 2019 · External reference
Precision surgery for hepatocellular carcinoma
10.1016/s2468-1253(24)00434-5 · 2025 · External reference
Programmed death ligand 1 expression in hepatocellular carcinoma: Relationship With clinical and pathological features
10.1002/hep.28710 · 2016 · External reference
Cancer immunotherapy using checkpoint blockade
10.1126/science.aar4060 · 2018 · External reference
Understanding the tumor immune microenvironment (TIME) for effective therapy
10.1038/s41591-018-0014-x · 2018 · External reference
Tumour-intrinsic resistance to immune checkpoint blockade
10.1038/s41577-019-0218-4 · 2020 · External reference
Synergistic effect of immune checkpoint blockade and anti-angiogenesis in cancer treatment
10.1186/s12943-019-0974-6 · 2019 · External reference
Combination locoregional and systemic therapies in hepatocellular carcinoma
10.1016/s2468-1253(24)00247-4 · 2025 · External reference
Reprogramming Immunodeficiency in Lung Metastases via PD-L1 siRNA Delivery and Antigen Capture of Nanosponge-Mediated Dendritic Cell Modulation
10.1021/acsnano.5c05395 · 2025 · External reference
Reprogramming Dysfunctional Dendritic Cells by a Versatile Catalytic Dual Oxide Antigen-Captured Nanosponge for Remotely Enhancing Lung Metastasis Immunotherapy
10.1021/acsnano.4c09525 · 2024 · External reference
Strategies for the development of metalloimmunotherapies
10.1038/s41551-024-01221-7 · 2024 · External reference
Amplifying STING activation by cyclic dinucleotide-manganese particles for local and systemic cancer metalloimmunotherapy
10.1038/s41565-021-00962-9 · 2021 · External reference
Manganese-Based Immunostimulatory Metal–Organic Framework Activates the cGAS-STING Pathway for Cancer Metalloimmunotherapy
10.1021/acsnano.3c03962 · 2023 · External reference
Molecular imaging in drug development
10.1038/nrd2290 · 2008 · External reference
Recent advances in magnetic nanoparticle-based multi-modal imaging
10.1039/c4cs00345d · 2015 · External reference
Chemistry of MRI Contrast Agents: Current Challenges and New Frontiers
10.1021/acs.chemrev.8b00363 · 2019 · External reference
Targeting the activity of T cells by membrane surface redox regulation for cancer theranostics
10.1038/s41565-022-01261-7 · 2023 · External reference
Redox-Activated Contrast-Enhanced T1-Weighted Imaging Visualizes Glutathione-Mediated Biotransformation Dynamics in the Liver
10.1021/acsnano.1c06026 · 2021 · External reference
Structure-Relaxivity Relationships of Magnetic Nanoparticles for Magnetic Resonance Imaging
10.1002/adma.201804567 · 2019 · External reference
19F magnetic resonance imaging (MRI): from design of materials to clinical applications
10.1021/cr500286d · 2015 · External reference
Nanoengineered Neutrophil as 19F-MRI Tracer for Alert Diagnosis and Severity Assessment of Acute Lung Injury
10.1002/adma.202401513 · 2024 · External reference
Elastic Polymer Coated Nanoparticles with Fast Clearance for 19F MR Imaging
10.1002/anie.202308565 · 2023 · External reference
Mechanical Interlocking of 144 Symmetrical 19F and Tetraphenylethylene for Magnetic Resonance-Fluorescence Dual Imaging
10.1021/jacs.5c00429 · 2025 · External reference
Visualizing enterohepatic circulation in vivo by sensitive 19F MRI with a fluorinated ferrous chelate-based small molecule probe
10.1016/j.biomaterials.2024.123073 · 2025 · External reference
Activatable Multiplexed 19F Magnetic Resonance Imaging Visualizes Reactive Oxygen and Nitrogen Species in Drug-Induced Acute Kidney Injury
10.1021/acs.analchem.1c03744 · 2021 · External reference
Fluorinated 1,7-DO2A-Based Iron(II) Complexes as Sensitive 19F MRI Molecular Probes for Visualizing Renal Dysfunction in Living Mice
10.1021/acs.analchem.4c02272 · 2024 · External reference
Single Fluorinated Agent for Multiplexed 19F-MRI with Micromolar Detectability Based on Dynamic Exchange
10.1002/anie.202100427 · 2021 · External reference
Sensitive Multichannel 19F Magnetic Resonance Imaging Enabled by Paramagnetic Fluorinated Ionic Liquid-Based Probes
10.1021/acsnano.4c17959 · 2025 · External reference
A Fluorinated Ionic Liquid-Based Activatable 19F MRI Platform Detects Biological Targets
10.1016/j.chempr.2020.01.023 · 2020 · External reference
Copper-based fluorinated MOFs for activatable multicolor 19F MRI and regulated cell death-promoting therapy of tumor
10.1016/j.nantod.2024.102364 · 2024 · External reference
Fluorinated Iron Metal-Organic Frameworks for Activatable 19F Magnetic Resonance Imaging and Synergistic Therapy of Tumors
10.1021/acs.nanolett.3c04402 · 2023 · External reference
Fluoropolymer-MOF Hybrids with Switchable Hydrophilicity for 19F MRI-Monitored Cancer Therapy
10.1021/acsnano.3c00694 · 2023 · External reference
Activatable 19F MRI Nanoprobes for Visualization of Biological Targets in Living Subjects
10.1002/adma.202005657 · 2021 · External reference
Structural Diversity of Zirconium Metal-Organic Frameworks and Effect on Adsorption of Toxic Chemicals
10.1021/jacs.0c10400 · 2020 · External reference
Anisotropic Self-Assembly of Asymmetric Mesoporous Hemispheres with Tunable Pore Structures at Liquid–Liquid Interfaces
10.1021/jacs.2c06436 · 2022 · External reference
Integrating the Pillared-Layer Strategy and Pore-Space Partition Method to Construct Multicomponent MOFs for C2H2/CO2 Separation
10.1021/jacs.0c00612 · 2020 · External reference
Advances in Biocompatible Metal-Organic Frameworks for Biomedical Applications
10.1002/adma.202503946 · 2025 · External reference
Recent Advances in Metal-Organic Frameworks for Applications in Magnetic Resonance Imaging
10.1021/acsami.2c10272 · 2022 · External reference
Zwitterionic Manganese and Gadolinium Metal–Organic Frameworks as Efficient Contrast Agents for in Vivo Magnetic Resonance Imaging
10.1021/acsami.7b09608 · 2017 · External reference
A Mn(III)-Sealed Metal–Organic Framework Nanosystem for Redox-Unlocked Tumor Theranostics
10.1021/acsnano.9b00300 · 2019 · External reference
Nanoscale Mixed-Ligand Metal–Organic Framework for X-ray Stimulated Cancer Therapy
10.1021/jacs.4c12140 · 2024 · External reference
Spatial Confinement of Platinum Nanoclusters in a Photoactive Metal–Organic Framework for Radiotherapy Enhancement and Redox-Mediated Immune Activation
10.1021/jacs.5c21748 · 2026 · External reference
PolyMOF Radiosensitizers as Nanocarriers with X-Ray-Triggered Dual-Gas Release for Enhanced Radiotherapy
10.1021/acsami.5c11614 · 2025 · External reference
Metal–Organic Framework Nanocarriers for Drug Delivery in Biomedical Applications
10.1007/s40820-020-00423-3 · 2020 · External reference
A Multifunctional Metal-Organic Frameworks-Based Nanoplatform for Tumor Imaging and Antimetastasis Immunotherapy by Exploiting the Versatility of Manganese Ions
10.1021/acsami.5c21942 · 2026 · External reference
Manganese-based tumor immunotherapy
10.1002/adma.202205409 · 2023 · External reference
Advancing engineering design strategies for targeted cancer nanomedicine
10.1038/s41568-025-00847-2 · 2025 · External reference
Paramagnetic fluorinated nanoemulsions for sensitive cellular fluorine-19 magnetic resonance imaging
10.1038/nmat4585 · 2016 · External reference
ZIF-8 Nanoparticles Evoke Pyroptosis for High-Efficiency Cancer Immunotherapy
10.1002/anie.202215307 · 2023 · External reference
Metal-Phenolic Vehicles Potentiate Cycle-Cascade Activation of Pyroptosis and cGAS-STING Pathway for Tumor Immunotherapy
10.1021/acsnano.4c08613 · 2024 · External reference
Tandem-controlled lysosomal assembly of nanofibres induces pyroptosis for cancer immunotherapy
10.1038/s41565-025-01857-9 · 2025 · External reference
Role of pyroptosis in inflammation and cancer
10.1038/s41423-022-00905-x · 2022 · External reference
Chemoimmunological Cascade Cancer Therapy Using Fluorine Assembly Nanomedicine
10.1021/acsnano.2c12600 · 2023 · External reference
ROS and the DNA damage response in cancer
10.1016/j.redox.2018.101084 · 2019 · External reference
Manganese Increases the Sensitivity of the cGAS-STING Pathway for Double-Stranded DNA and Is Required for the Host Defense against DNA Viruses
10.1016/j.immuni.2018.03.017 · 2018 · External reference
Dendritic cell type 3 arises from Ly6C+ monocyte-dendritic cell progenitors
10.1016/j.immuni.2023.07.001 · 2023 · External reference
Hepatocellular carcinoma
10.1038/s41572-020-00240-3 · 2021 · External reference
Tumor-associated macrophages in tumor metastasis: biological roles and clinical therapeutic applications
10.1186/s13045-019-0760-3 · 2019 · External reference
Succinate preserves CD8+ T cell fitness to augment antitumor immunity
10.1016/j.immuni.2025.07.017 · 2025 · External reference
An intra-tumoral niche maintains and differentiates stem-like CD8 T cells
10.1038/s41586-019-1836-5 · 2019 · External reference
Gut microbial metabolite butyrate improves anticancer therapy by regulating intracellular calcium homeostasis
10.1097/hep.0000000000000047 · 2023 · External reference
