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References from Modular Assembly of Systems for Antibody-Directed Enzyme Prodrug Therapy. Local targets link to admitted publications; unresolved targets remain external evidence.
Bystander Killing of Tumour Cells by Antibody-Targeted Enzymatic Activation of a Glucuronide Prodrug
10.1038/sj.bjc.6690221 · 1999 · External reference
Bystander Effect in Antibody-Drug Conjugates: Navigating the Fine Line in Tumor Heterogeneity
10.1016/j.critrevonc.2025.104979 · 2025 · External reference
Optimisation of Small-Scale Coupling of A5B7 Monoclonal Antibody to Carboxypeptidase G2
10.1016/0022-1759(93)90257-8 · 1993 · External reference
Anti-Tumor Effects of Antibody-Alkaline Phosphatase Conjugates in Combination with Etoposide Phosphate
10.1073/pnas.85.13.4842 · 1988 · External reference
A Novel Targeted Delivery System Wtilizing a Cephalosporin Oncolytic Prodrug Activated by an Antibody B-Lactamase Conjugate for the Treatment of Cancer
10.1016/s0960-894x(01)81083-0 · 1991 · External reference
Toward Antibody-Directed Enzyme Prodrug Therapy with the T268g Mutant of Human Carboxypeptidase A1 and Novel in Vivo Stable Prodrugs of Methotrexate
10.1074/jbc.272.25.15804 · 1997 · External reference
Molecular and Functional Characterisation of a Fusion Protein Suited for Tumour Specific Prodrug Activation
10.1038/bjc.1992.47 · 1992 · External reference
Sustained Tumor Regression of Human Colorectal Cancer Xenografts Using a Multifunctional Mannosylated Fusion Protein in Antibody-Directed Enzyme Prodrug Therapy
10.1158/1078-0432.814.11.2 · 2005 · External reference
Glycoforms Obtained by Expression in Pichia Pastoris Improve Cancer Targeting Potential of a Recombinant Antibody-Enzyme Fusion Protein
10.1093/glycob/cwh001 · 2004 · External reference
Translating Antibody Directed Enzyme Prodrug Therapy (ADEPT) and Prospects for Combination
10.1080/14712598.2017.1247802 · 2017 · External reference
A Phase I Trial of Antibody Directed Enzyme Prodrug Therapy (ADEPT) in Patients with Advanced Colorectal Carcinoma or Other Cea Producing Tumours
10.1038/sj.bjc.6600517 · 2002 · External reference
Expression of Recombinant Antibodies
10.3389/fimmu.2013.00217 · 2013 · External reference
Playing Catch-up with Escherichia Coli: Using Yeast to Increase Success Rates in Recombinant Protein Production Experiments
10.3389/fmicb.2014.00085 · 2014 · External reference
The Evolution of SNAP-Tag Labels
10.1021/acs.biomac.2c01238 · 2023 · External reference
A General Method for the Covalent Labeling of Fusion Proteins with Small Molecules in Vivo
10.1038/nbt765 · 2003 · External reference
Genetic Targeting of Chemical Indicators in Vivo
10.1038/nmeth.3207 · 2015 · External reference
Post-Translational Covalent Assembly of CAR and SynNotch Receptors for Programmable Antigen Targeting
10.1038/s41467-023-37863-5 · 2023 · External reference
Megamolecule Self-Assembly Networks: A Combined Computational and Experimental Design Strategy
10.1021/jacs.4c11892 · 2024 · External reference
Solid-Phase Synthesis of Megamolecules
10.1021/jacs.9b12003 · 2020 · External reference
One-Step Site-Specific Antibody Fragment Auto-Conjugation Using SNAP-Tag Technology
10.1038/s41596-019-0214-y · 2019 · External reference
Development of SNAP-Tag Based Nanobodies as Secondary Antibody Mimics for Indirect Immunofluorescence Assays
10.3390/cells14100691 · 2025 · External reference
Rapid Optical Imaging of Egf Receptor Expression with a Single-Chain Antibody SNAP-Tag Fusion Protein
10.1007/s00259-010-1482-5 · 2010 · External reference
The Covalent SNAPTag for Protein Display Quantification and Low-Ph Protein Engineering
10.1016/j.jbiotec.2020.06.011 · 2020 · External reference
SNAP-Tag Technology: A Useful Tool to Determine Affinity Constants and Other Functional Parameters of Novel Antibody Fragments
10.1021/acs.bioconjchem.6b00315 · 2016 · External reference
Antibody-Based Cancer Therapy
10.1038/s41388-021-01811-8 · 2021 · External reference
Precision Modification of Native Antibodies
10.1021/acs.bioconjchem.1c00342 · 2021 · External reference
Genetic and Biochemical Characterization of Ges-5, an Extended-Spectrum Class a Beta-Lactamase from Klebsiella Pneumoniae
10.1016/j.diagmicrobio.2007.02.013 · 2007 · External reference
Crystal Structure of Carboxypeptidase G2, a Bacterial Enzyme with Applications in Cancer Therapy
10.1016/s0969-2126(97)00191-3 · 1997 · External reference
Beta-Galactosidase: From Its Source and Applications to Its Recombinant Form
10.1002/bab.2137 · 2022 · External reference
Therapeutic Significance of Beta-Glucuronidase Activity and Its Inhibitors: A Review
10.1016/j.ejmech.2019.111921 · 2020 · External reference
Alteration of Physicochemical Properties for Antibody-Drug Conjugates and Their Impact on Stability
10.1016/j.xphs.2019.08.006 · 2020 · External reference
Transglutaminase-Based Chemo-Enzymatic Conjugation Approach Yields Homogeneous Antibody-Drug Conjugates
10.1021/bc400574z · 2014 · External reference
Site-Specific and Stoichiometric Modification of Antibodies by Bacterial Transglutaminase
10.1002/anie.201004243 · 2010 · External reference
Orthogonal Conjugation Via Endoglycosidase and Microbial Transglutaminase Enables Efficient Synthesis of Dual-Payload Antibody-Drug Conjugates
10.1021/acschembio.6c00229 · 2026 · External reference
Probing the Limits of Q-Tag Bioconjugation of Antibodies
10.1039/c9cc02303h · 2019 · External reference
Cu-Free Click Cycloaddition Reactions in Chemical Biology
10.1039/b901970g · 2010 · External reference
Molecular Mechanism of Her2 Rapid Internalization and Redirected Trafficking Induced by Anti-Her2 Biparatopic Antibody
2020 · External reference
Endocytosis and Sorting of ERBB2 and the Site of Action of Cancer Therapeutics Trastuzumab and Geldanamycin
10.1091/mbc.e04-07-0591 · 2004 · External reference
Visible Fluorescence Detection of Type III Protein Secretion from Bacterial Pathogens
10.1021/ja102257v · 2010 · External reference
Calcium Phosphate –Mediated Transfection of Eukaryotic Cells
10.1101/pdb.prot095430 · 2005 · External reference
Curcumin-Based Benzothiazepane Analogues Exhibit Selective Anti-Cancer Activity in Hct-116 Cells Via Precipitated Particle Formation and Internalisation
10.1016/j.biopha.2025.118926 · 2026 · External reference
Synthesis and Biological Evaluations of a Monomethylauristatin E Glucuronide Prodrug for Selective Cancer Chemotherapy
10.1016/j.ejmech.2013.06.037 · 2013 · External reference
Antibody–Drug Conjugate Payloads; Study of Auristatin Derivatives
10.1248/cpb.c19-00853 · 2020 · External reference
Cac10-Vcmmae, an Anti-CD30-Monomethyl Auristatin E Conjugate with Potent and Selective Antitumor Activity
10.1182/blood-2003-01-0039 · 2003 · External reference
Site-Specific Protein Labeling with SNAP-Tags
10.1002/0471140864.ps3001s73 · 2013 · External reference
The Effect of Particle Size on Drug Bioavailability in Various Parts of the Body
10.1016/j.pscia.2023.100031 · 2024 · External reference
A New Concept for Macromolecular Therapeutics in Cancer Chemotherapy: Mechanism of Tumoritropic Accumulation of Proteins and the Antitumor Agent Smancs
1986 · External reference
Antibody Directed Enzyme Prodrug Therapy (ADEPT): Trials and Tribulations
10.1016/j.addr.2017.09.009 · 2017 · External reference
Genetically Encoded Optochemical Probes for Simultaneous Fluorescence Reporting and Light Activation of Protein Function with Two-Photon Excitation
10.1021/ja5055862 · 2014 · External reference
Optogenetics with Atomic Precision: A Comprehensive Review of Optical Control of Protein Function through Genetic Code Expansion
10.1021/acs.chemrev.4c00224 · 2025 · External reference
A Guide to Designing Photocontrol in Proteins: Methods, Strategies and Applications
10.1515/hsz-2021-0417 · 2022 · External reference
Photopharmacology: Beyond Proof of Principle
10.1021/ja413063e · 2014 · External reference
Optical Control of Protein Function through Unnatural Amino Acid Mutagenesis and Other Optogenetic Approaches
10.1021/cb500176x · 2014 · External reference
Optogenetics: A Primer for Chemists
10.1002/cbic.201800013 · 2018 · External reference
Phosphine-Activated Lysine Analogues for Fast Chemical Control of Protein Subcellular Localization and Protein Sumoylation
10.1002/cbic.201900464 · 2020 · External reference
Diels-Alder Reaction-Triggered Bioorthogonal Protein Decaging in Living Cells
10.1038/nchembio.1656 · 2014 · External reference
Palladium-Triggered Deprotection Chemistry for Protein Activation in Living Cells
10.1038/nchem.1887 · 2014 · External reference
Unnatural Amino Acid Mutagenesis of Fluorescent Proteins
10.1002/anie.201204668 · 2012 · External reference
Probing the Role of Aurora Kinase a Threonylation with Site-Specific Lysine Threonylation
10.1021/acschembio.1c00682 · 2022 · External reference
A Sirtuin-Dependent T7 RNA Polymerase Variant
10.1021/acssynbio.3c00607 · 2024 · External reference
The Incorporation of a Photoisomerizable Amino Acid into Proteins in E. Coli
10.1021/ja055467u · 2006 · External reference
X-Ray Crystallography Deciphers the Activity of Broad-Spectrum Boronic Acid Beta-Lactamase Inhibitors
10.1021/acsmedchemlett.8b00607 · 2019 · External reference
One Ring to Rule Them All: Current Trends in Combating Bacterial Resistance to the Beta-Lactams
10.1002/pro.2889 · 2016 · External reference
Molecular Modeling Approach to Predict a Binding Mode for the Complex Methotrexate-Carboxypeptidase G2
10.1007/s00894-011-1196-z · 2012 · External reference
The Structure of Β-Lactamases
10.1098/rstb.1980.0049 · 1980 · External reference
Structural and Mechanistic Basis for Extended-Spectrum Drug-Resistance Mutations in Altering the Specificity of TEM, CTX-M, and KPC Beta-Lactamases
10.3389/fmolb.2018.00016 · 2018 · External reference
