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References from Phosphatidylserine-Engineered Lipid Nanoparticles Enable Systemic mRNA Delivery to the Central Nervous System. Local targets link to admitted publications; unresolved targets remain external evidence.
Progress and prospects of mRNA-based drugs in pre-clinical and clinical applications
10.1038/s41392-024-02002-z · 2024 · External reference
A new strategy for the extrahepatic delivery of lipid-based nanomedicines: a protein corona-mediated selective targeting system based on an ionizable cationic lipid library
10.1039/d5pm00079c · 2025 · External reference
Microbiome-Derived Lipid Nanoparticles for Improved Immunogenicity of mRNA Vaccines
10.1021/acsmaterialslett.3c01642 · 2024 · External reference
On the mechanism of tissue-specific mRNA delivery by selective organ targeting nanoparticles
10.1073/pnas.2109256118 · 2021 · External reference
Post-Conjugation Process for Antibody-Conjugated Lipid Nanoparticles Enabling Tunable Antibody Surface Density for Targeted RNA Delivery
10.1021/acsnano.5c21719 · 2026 · External reference
Curcumin-Loaded Biohybrid Nanoparticles Modulating Inflammation and Reducing Lipid Accumulation in Atherosclerotic Plaques for Atherosclerosis Treatment
10.1021/acsmaterialslett.5c01506 · 2026 · External reference
Blood–brain-barrier-crossing lipid nanoparticles for mRNA delivery to the central nervous system
10.1038/s41563-024-02114-5 · 2025 · External reference
High-Throughput In Vivo Screening Identifies Structural Factors Driving mRNA Lipid Nanoparticle Delivery to the Brain
10.1021/acsnano.5c19138 · 2026 · External reference
Lipid Nanoparticles for Brain Tumor Theranostics: Challenges and Status
10.1021/acs.bioconjchem.4c00293 · 2024 · External reference
AI-Validated Brain Targeted mRNA Lipid Nanoparticles with Neuronal Tropism
10.1021/acsnano.4c15013 · 2025 · External reference
The blood–brain barriers: novel nanocarriers for central nervous system diseases
10.1186/s12951-025-03247-8 · 2025 · External reference
Peptide-Functionalized Lipid Nanoparticles for Targeted Systemic mRNA Delivery to the Brain
10.1021/acs.nanolett.4c05186 · 2025 · External reference
Design and Targeting Strategies in Nanotheranostics for Glioma
10.1021/acsnanomed.5c00071 · 2026 · External reference
Strategies and challenges to improve the performance of tumor-associated active targeting
10.1039/d0tb00289e · 2020 · External reference
Fabrication of active targeting lipid nanoparticles: Challenges and perspectives
10.1016/j.mtadv.2022.100299 · 2022 · External reference
Incorporation of phosphatidylserine improves efficiency of lipid based gene delivery systems
10.1016/j.ejpb.2022.02.007 · 2022 · External reference
Immune response to the components of lipid nanoparticles for ribonucleic acid therapeutics
10.1016/j.copbio.2023.103049 · 2024 · External reference
Phosphatidylserine (PS) and phosphatidylglycerol (PG) nanodispersions as potential anti-inflammatory therapeutics: Comparison of in vitro activity and impact of pegylation
10.1016/j.nano.2019.102096 · 2020 · External reference
Phosphatidylserine Lipid Nanoparticles Promote Systemic RNA Delivery to Secondary Lymphoid Organs
10.1021/acs.nanolett.2c03234 · 2022 · External reference
Delivering mRNA to Secondary Lymphoid Tissues by Phosphatidylserine-Loaded Lipid Nanoparticles
10.1002/adhm.202202528 · 2023 · External reference
Exploring the Effects of Incorporating Different Bioactive Phospholipids into Messenger Ribonucleic Acid Lipid Nanoparticle (mRNA LNP) Formulations
10.1021/acsbiomedchemau.4c00085 · 2025 · External reference
Phosphatidylserine in the brain: Metabolism and function
10.1016/j.plipres.2014.06.002 · 2014 · External reference
Age-related changes in central nervous system phosphatidylserine decarboxylase activity
10.1002/jnr.10385 · 2002 · External reference
Phosphatidylserine in the Nervous System: Cytoplasmic Regulator of the AKT and PKC Signaling Pathways and Extracellular “Eat-Me” Signal in Microglial Phagocytosis
10.1007/s12035-022-03133-6 · 2023 · External reference
Formulation of lipid nanoparticles containing ginsenoside Rg2 and protopanaxadiol for highly efficient delivery of mRNA
10.1039/d4bm01070a · 2024 · External reference
Protocol for formulation and evaluation of phytosterol-based lipid nanoparticles as cholesterol alternatives for mRNA delivery
10.1016/j.xpro.2026.104392 · 2026 · External reference
Glucose–Nucleobase Pseudo Base Pairs: Biomolecular Interactions within DNA
10.1002/anie.201603510 · 2016 · External reference
Carbohydrate-nucleotide interaction The effects of mono- and disaccharides on the solution structure of AMP, dAMP, ATP, GMP, dGMP, and GTP studied by FTIR difference spectroscopy
10.1016/s0162-0134(96)00097-9 · 1997 · External reference
The role of phosphatidylserine recognition receptors in multiple biological functions
10.1186/s11658-020-00214-z · 2020 · External reference
The role of phosphatidylserine in recognition of apoptotic cells by phagocytes
10.1038/sj.cdd.4400404 · 1998 · External reference
Protective Effect of 20(S)-Protopanaxadiol on D-Gal-Induced Cognitively Impaired Mice Based on Its Target Protein Brain-type Creatine Kinase
10.1021/acs.jafc.2c07889 · 2023 · External reference
20(S)-protopanaxadiol targets brain-enriched adenylate kinase 5 to improve cognitive function via regulating hippocampal neural plasticity
10.1016/j.phymed.2025.157711 · 2026 · External reference
Biological Function and Immunotherapy Utilizing Phosphatidylserine-based Nanoparticles
10.1080/08820139.2020.1738456 · 2020 · External reference
Phosphatidylserine-decorated delivery platform helps alleviate acute lung injury via potentiating macrophage targeting
10.1016/j.jlr.2025.100799 · 2025 · External reference
Enhancing the Endocytosis of Phosphatidylserine-Containing Liposomes through Tim4 by Modulation of Membrane Fluidity
10.1021/acs.molpharmaceut.1c00645 · 2021 · External reference
Delivering mRNA to Secondary Lymphoid Tissues by Phosphatidylserine-Loaded Lipid Nanoparticles
10.1002/adhm.202202528 · ExternalCitation · doi-reference
Glucose–Nucleobase Pseudo Base Pairs: Biomolecular Interactions within DNA
10.1002/anie.201603510 · ExternalCitation · doi-reference
Age-related changes in central nervous system phosphatidylserine decarboxylase activity
10.1002/jnr.10385 · ExternalCitation · doi-reference
Phosphatidylserine in the Nervous System: Cytoplasmic Regulator of the AKT and PKC Signaling Pathways and Extracellular “Eat-Me” Signal in Microglial Phagocytosis
10.1007/s12035-022-03133-6 · ExternalCitation · doi-reference
Immune response to the components of lipid nanoparticles for ribonucleic acid therapeutics
10.1016/j.copbio.2023.103049 · ExternalCitation · doi-reference
Incorporation of phosphatidylserine improves efficiency of lipid based gene delivery systems
10.1016/j.ejpb.2022.02.007 · ExternalCitation · doi-reference
Phosphatidylserine-decorated delivery platform helps alleviate acute lung injury via potentiating macrophage targeting
10.1016/j.jlr.2025.100799 · ExternalCitation · doi-reference
Fabrication of active targeting lipid nanoparticles: Challenges and perspectives
10.1016/j.mtadv.2022.100299 · ExternalCitation · doi-reference
Phosphatidylserine (PS) and phosphatidylglycerol (PG) nanodispersions as potential anti-inflammatory therapeutics: Comparison of in vitro activity and impact of pegylation
10.1016/j.nano.2019.102096 · ExternalCitation · doi-reference
20(S)-protopanaxadiol targets brain-enriched adenylate kinase 5 to improve cognitive function via regulating hippocampal neural plasticity
10.1016/j.phymed.2025.157711 · ExternalCitation · doi-reference
Phosphatidylserine in the brain: Metabolism and function
10.1016/j.plipres.2014.06.002 · ExternalCitation · doi-reference
Protocol for formulation and evaluation of phytosterol-based lipid nanoparticles as cholesterol alternatives for mRNA delivery
10.1016/j.xpro.2026.104392 · ExternalCitation · doi-reference
Carbohydrate-nucleotide interaction The effects of mono- and disaccharides on the solution structure of AMP, dAMP, ATP, GMP, dGMP, and GTP studied by FTIR difference spectroscopy
10.1016/s0162-0134(96)00097-9 · ExternalCitation · doi-reference
Lipid Nanoparticles for Brain Tumor Theranostics: Challenges and Status
10.1021/acs.bioconjchem.4c00293 · ExternalCitation · doi-reference
Protective Effect of 20(S)-Protopanaxadiol on D-Gal-Induced Cognitively Impaired Mice Based on Its Target Protein Brain-type Creatine Kinase
10.1021/acs.jafc.2c07889 · ExternalCitation · doi-reference
Enhancing the Endocytosis of Phosphatidylserine-Containing Liposomes through Tim4 by Modulation of Membrane Fluidity
10.1021/acs.molpharmaceut.1c00645 · ExternalCitation · doi-reference
Phosphatidylserine Lipid Nanoparticles Promote Systemic RNA Delivery to Secondary Lymphoid Organs
10.1021/acs.nanolett.2c03234 · ExternalCitation · doi-reference
Peptide-Functionalized Lipid Nanoparticles for Targeted Systemic mRNA Delivery to the Brain
10.1021/acs.nanolett.4c05186 · ExternalCitation · doi-reference
Exploring the Effects of Incorporating Different Bioactive Phospholipids into Messenger Ribonucleic Acid Lipid Nanoparticle (mRNA LNP) Formulations
10.1021/acsbiomedchemau.4c00085 · ExternalCitation · doi-reference
Microbiome-Derived Lipid Nanoparticles for Improved Immunogenicity of mRNA Vaccines
10.1021/acsmaterialslett.3c01642 · ExternalCitation · doi-reference
Curcumin-Loaded Biohybrid Nanoparticles Modulating Inflammation and Reducing Lipid Accumulation in Atherosclerotic Plaques for Atherosclerosis Treatment
10.1021/acsmaterialslett.5c01506 · ExternalCitation · doi-reference
AI-Validated Brain Targeted mRNA Lipid Nanoparticles with Neuronal Tropism
10.1021/acsnano.4c15013 · ExternalCitation · doi-reference
High-Throughput In Vivo Screening Identifies Structural Factors Driving mRNA Lipid Nanoparticle Delivery to the Brain
10.1021/acsnano.5c19138 · ExternalCitation · doi-reference
Post-Conjugation Process for Antibody-Conjugated Lipid Nanoparticles Enabling Tunable Antibody Surface Density for Targeted RNA Delivery
10.1021/acsnano.5c21719 · ExternalCitation · doi-reference
Design and Targeting Strategies in Nanotheranostics for Glioma
10.1021/acsnanomed.5c00071 · ExternalCitation · doi-reference
Progress and prospects of mRNA-based drugs in pre-clinical and clinical applications
10.1038/s41392-024-02002-z · ExternalCitation · doi-reference
Blood–brain-barrier-crossing lipid nanoparticles for mRNA delivery to the central nervous system
10.1038/s41563-024-02114-5 · ExternalCitation · doi-reference
The role of phosphatidylserine in recognition of apoptotic cells by phagocytes
10.1038/sj.cdd.4400404 · ExternalCitation · doi-reference
Strategies and challenges to improve the performance of tumor-associated active targeting
10.1039/d0tb00289e · ExternalCitation · doi-reference
Formulation of lipid nanoparticles containing ginsenoside Rg2 and protopanaxadiol for highly efficient delivery of mRNA
10.1039/d4bm01070a · ExternalCitation · doi-reference
A new strategy for the extrahepatic delivery of lipid-based nanomedicines: a protein corona-mediated selective targeting system based on an ionizable cationic lipid library
10.1039/d5pm00079c · ExternalCitation · doi-reference
On the mechanism of tissue-specific mRNA delivery by selective organ targeting nanoparticles
10.1073/pnas.2109256118 · ExternalCitation · doi-reference
Biological Function and Immunotherapy Utilizing Phosphatidylserine-based Nanoparticles
10.1080/08820139.2020.1738456 · ExternalCitation · doi-reference
The role of phosphatidylserine recognition receptors in multiple biological functions
10.1186/s11658-020-00214-z · ExternalCitation · doi-reference
The blood–brain barriers: novel nanocarriers for central nervous system diseases
10.1186/s12951-025-03247-8 · ExternalCitation · doi-reference