References

Inhibition of cytochrome bd oxidase in Mycobacterium tuberculosis by benzothiazole amides

10.1016/j.bmc.2025.118323 · ExternalCitation · doi-reference

Targeting bacterial energetics to produce new antimicrobials

10.1016/j.drup.2017.11.001 · ExternalCitation · doi-reference

Discovery of 1-hydroxy-2-methylquinolin-4(1H)-one derivatives as new cytochrome bd oxidase inhibitors for tuberculosis therapy

10.1016/j.ejmech.2022.114896 · ExternalCitation · doi-reference

Mycobacterium tuberculosis gene expression during adaptation to stationary phase and low-oxygen dormancy

10.1016/j.tube.2004.02.003 · ExternalCitation · doi-reference

Emergence of bedaquiline-resistant tuberculosis and of multidrug-resistant and extensively drug-resistant Mycobacterium tuberculosis strains with rpoB Ile491Phe mutation not detected by Xpert MTB/RIF in Mozambique: a retrospective observational study

10.1016/s1473-3099(23)00498-x · ExternalCitation · doi-reference

Global control of tuberculosis: from extensively drug-resistant to untreatable tuberculosis

10.1016/s2213-2600(14)70031-1 · ExternalCitation · doi-reference

Bedaquiline resistance in patients with drug-resistant tuberculosis in Cape Town, South Africa: a retrospective longitudinal cohort study

10.1016/s2666-5247(23)00172-6 · ExternalCitation · doi-reference

A Series of Pyrazolo-Quinazoline Amines Inhibits the Cytochrome bd Oxidase in Mycobacterium tuberculosis

10.1021/acs.jmedchem.5c01616 · ExternalCitation · doi-reference

Identification of 2-Aryl-Quinolone Inhibitors of Cytochrome bd and Chemical Validation of Combination Strategies for Respiratory Inhibitors against Mycobacterium tuberculosis

10.1021/acsinfecdis.2c00283 · ExternalCitation · doi-reference

Pyrazolo[1,5- a]pyridine Inhibitor of the Respiratory Cytochrome bcc Complex for the Treatment of Drug-Resistant Tuberculosis

10.1021/acsinfecdis.8b00225 · ExternalCitation · doi-reference

Synthesis and Biological Evaluation of Aurachin D Analogues as Inhibitors of Mycobacterium tuberculosis Cytochrome bd Oxidase

10.1021/acsmedchemlett.2c00401 · ExternalCitation · doi-reference

Pyrroloquinolone-Based Compounds as a Novel Antimycobacterial Chemotype

10.1021/acsmedchemlett.5c00183 · ExternalCitation · doi-reference

Cytochrome bd from Azotobacter vinelandii: evidence for high-affinity oxygen binding

10.1021/bi700862u · ExternalCitation · doi-reference

Lead optimization of a novel series of imidazo[1,2-a]pyridine amides leading to a clinical candidate (Q203) as a multi- and extensively-drug-resistant anti-tuberculosis agent

10.1021/jm5003606 · ExternalCitation · doi-reference

A small-molecule nitroimidazopyran drug candidate for the treatment of tuberculosis

10.1038/35016103 · ExternalCitation · doi-reference

Discovery of Q203, a potent clinical candidate for the treatment of tuberculosis

10.1038/nm.3262 · ExternalCitation · doi-reference

Advances in the development of new tuberculosis drugs and treatment regimens

10.1038/nrd4001 · ExternalCitation · doi-reference

Plasticity of the Mycobacterium tuberculosis respiratory chain and its impact on tuberculosis drug development

10.1038/s41467-019-12956-2 · ExternalCitation · doi-reference

An amiloride derivative is active against the F(1)F(o)-ATP synthase and cytochrome bd oxidase of Mycobacterium tuberculosis

10.1038/s42003-022-03110-8 · ExternalCitation · doi-reference

Structure guided generation of thieno[3,2-d]pyrimidin-4-amine Mycobacterium tuberculosis bd oxidase inhibitors

10.1039/d0md00398k · ExternalCitation · doi-reference

Treatment of Highly Drug-Resistant Pulmonary Tuberculosis

10.1056/nejmc2009939 · ExternalCitation · doi-reference

A 24-Week, All-Oral Regimen for Rifampin-Resistant Tuberculosis

10.1056/nejmoa2117166 · ExternalCitation · doi-reference

Bedaquiline-Pretomanid-Linezolid Regimens for Drug-Resistant Tuberculosis

10.1056/nejmoa2119430 · ExternalCitation · doi-reference

Changes in energy metabolism of Mycobacterium tuberculosis in mouse lung and under in vitro conditions affecting aerobic respiration

10.1073/pnas.0507850102 · ExternalCitation · doi-reference

Aerobic respiratory chain of Escherichia coli is not allowed to work in fully uncoupled mode

10.1073/pnas.1108217108 · ExternalCitation · doi-reference

Exploiting the synthetic lethality between terminal respiratory oxidases to kill Mycobacterium tuberculosis and clear host infection

10.1073/pnas.1706139114 · ExternalCitation · doi-reference

The cytochrome bd quinol oxidase in Escherichia coli has an extremely high oxygen affinity and two oxygen-binding haems: implications for regulation of activity in vivo by oxygen inhibition

10.1099/00221287-142-4-755 · ExternalCitation · doi-reference

A diarylquinoline drug active on the ATP synthase of Mycobacterium tuberculosis

10.1126/science.1106753 · ExternalCitation · doi-reference

An electron transfer path connects subunits of a mycobacterial respiratory supercomplex

10.1126/science.aat8923 · ExternalCitation · doi-reference

Randomized pilot trial of eight weeks of bedaquiline (TMC207) treatment for multidrug-resistant tuberculosis: long-term outcome, tolerability, and effect on emergence of drug resistance

10.1128/aac.06126-11 · ExternalCitation · doi-reference

Tuberculosis and lung damage: from epidemiology to pathophysiology

10.1183/16000617.0077-2017 · ExternalCitation · doi-reference

Dual inhibition of the terminal oxidases eradicates antibiotic-tolerant Mycobacterium tuberculosis

10.15252/emmm.202013207 · ExternalCitation · doi-reference

In vitro Study of Bedaquiline Resistance in Mycobacterium tuberculosis Multi-Drug Resistant Clinical Isolates

10.3389/fmicb.2020.559469 · ExternalCitation · doi-reference

First and Second-Line Anti-Tuberculosis Drug-Resistance Patterns in Pulmonary Tuberculosis Patients in Zambia

10.3390/antibiotics12010166 · ExternalCitation · doi-reference

Syntheses and Structure-Activity Relationships of N-Phenethyl-Quinazolin-4-yl-Amines as Potent Inhibitors of Cytochrome bd Oxidase in Mycobacterium tuberculosis

10.3390/app11199092 · ExternalCitation · doi-reference