Research graph
References from Modified Thymosin Alpha 1 Distributes and Inhibits the Growth of Lung Cancer in Vivo. Local targets link to admitted publications; unresolved targets remain external evidence.
Lung cancer
10.1038/513s1a · 2014 · External reference
Administration strategies for proteins and peptides
10.1016/j.ijpharm.2014.10.059 · 2014 · External reference
From lab to bedside: emerging clinical applications of thymosin alpha 1
10.1517/14712590902911412 · 2009 · External reference
Thymosin alpha1 plus routine treatment inhibit inflammatory reaction and improve the quality of life in AECOPD patients
10.3109/08923973.2015.1069837 · 2015 · External reference
Thymosin alpha1 is a time and dose-dependent antagonist of dexamethasone-induced apoptosis of murine thymocytes in vitro
10.1016/s0192-0561(00)00065-5 · 2000 · External reference
CD4/CD8 + T cells, DC subsets, Foxp3, and IDO expression are predictive indictors of gastric cancer prognosis
10.1002/cam4.2596 · 2019 · External reference
HBV-specific CD4+ cytotoxic T cells in hepatocellular carcinoma are less cytolytic toward tumor cells and suppress CD8+ T cell-mediated antitumor immunity
10.1111/apm.12704 · 2017 · External reference
NAFLD causes selective CD4(+) T lymphocyte loss and promotes hepatocarcinogenesis
10.1038/nature16969 · 2016 · External reference
Thymosin alpha 1: biological activities, applications and genetic engineering production
10.1016/j.peptides.2010.07.026 · 2010 · External reference
Thymosin alpha1: burying secrets in the thymus
10.1517/14712598.2015.1044895 · 2015 · External reference
Thymosin alpha-1-transformed Bifidobacterium promotes T cell proliferation and maturation in mice by oral administration
10.1016/j.intimp.2012.12.031 · 2013 · External reference
Interleukin 2 receptor expression in patients with head and neck squamous carcinoma. Effects of thymosin alpha 1 in vitro
10.1001/archotol.1989.01860350079019 · 1989 · External reference
Fusion of thymosin alpha 1 with mutant IgG1 CH3 prolongs half-life and enhances antitumor effects in vivo
10.1016/j.intimp.2019.05.047 · 2019 · External reference
A Reappraisal of Thymosin Alpha1 in Cancer Therapy
10.3389/fonc.2019.00873 · 2019 · External reference
Thymosin alpha1 and cancer: action on immune effector and tumor target cells
10.1111/j.1749-6632.2012.06697.x · 2012 · External reference
Sequential chemoimmunotherapy for advanced non-small cell lung cancer using cisplatin, etoposide, thymosin-alpha 1 and interferon-alpha 2a
10.1016/0959-8049(95)00477-7 · 1995 · External reference
Combined treatment with thymosin-alpha1 and low-dose interferon-alpha after ifosfamide in non-small cell lung cancer: a phase-II controlled trial
1996 · External reference
Thymosin alpha1 in melanoma: from the clinical trial setting to the daily practice and beyond
10.1111/j.1749-6632.2012.06757.x · 2012 · External reference
Large randomized study of thymosin alpha 1, interferon alfa, or both in combination with dacarbazine in patients with metastatic melanoma
10.1200/jco.2009.25.5208 · 2010 · External reference
Combined treatment with thymosin-alpha1 and low dose interferon-alpha after dacarbazine in advanced melanoma
10.1097/00008390-200010020-00012 · 2000 · External reference
Generation of a novel long-acting thymosin alpha1-Fc fusion protein and its efficacy for the inhibition of breast cancer in vivo
10.1016/j.biopha.2018.09.064 · 2018 · External reference
A modified thymosin alpha 1 inhibits the growth of breast cancer both in vitro and in vivo: suppressment of cell proliferation, inducible cell apoptosis and enhancement of targeted anticancer effects
10.1007/s10495-015-1151-z · 2015 · External reference
Immunomodulatory and enhanced antitumor activity of a modified thymosin alpha1 in melanoma and lung cancer
10.1016/j.ijpharm.2018.06.041 · 2018 · External reference
Effect of a C-end rule modification on antitumor activity of thymosin alpha1
10.1016/j.biochi.2018.08.001 · 2018 · External reference
C-end rule peptides mediate neuropilin-1-dependent cell, vascular, and tissue penetration
10.1073/pnas.0908201106 · 2009 · External reference
Tumor-penetrating iRGD peptide inhibits metastasis
10.1158/1535-7163.mct-14-0366 · 2015 · External reference
A tumor-penetrating peptide enhances circulation-independent targeting of peritoneal carcinomatosis
10.1016/j.jconrel.2015.06.009 · 2015 · External reference
Small GTPase Rab21 regulates cell adhesion and controls endosomal traffic of beta1-integrins
10.1083/jcb.200509019 · 2006 · External reference
TGFbeta3-mediated induction of Periostin facilitates head and neck cancer growth and is associated with metastasis
10.1038/srep20587 · 2016 · External reference
Thymosin alpha-1 treatment in chronic hepatitis B
10.1517/14712598.2015.1007948 · 2015 · External reference
Comparison of the efficacy of thymosin alpha-1 and interferon alpha in the treatment of chronic hepatitis B: a meta-analysis
10.1016/j.antiviral.2007.10.014 · 2008 · External reference
Efficacy of thymosin alpha1 in patients with chronic hepatitis B: a randomized, controlled trial
10.1002/hep.510270527 · 1998 · External reference
Combination treatment using thymosin alpha 1 and interferon after cyclophosphamide is able to cure Lewis lung carcinoma in mice
10.1007/bf01771450 · 1990 · External reference
Anti-tumor effect of combined treatment with thymosin alpha 1 and interleukin-2 after 5-fluorouracil in liver metastases from colorectal cancer in rats
10.1002/ijc.2910570516 · 1994 · External reference
Tumour ischaemia by interferon-gamma resembles physiological blood vessel regression
10.1038/nature22311 · 2017 · External reference
Fas expression by tumor stroma is required for cancer eradication
10.1073/pnas.1218295110 · 2013 · External reference
Tumor angiogenesis: therapeutic implications
10.1056/nejm197108122850711 · 1971 · External reference
Platelet Endothelial Cell Adhesion Molecule 1 (PECAM-1/CD31): A Multifunctional Vascular Cell Adhesion Molecule
10.1016/s1050-1738(97)00049-2 · 1997 · External reference
CD31 regulates metastasis by inducing epithelial-mesenchymal transition in hepatocellular carcinoma via the ITGB1-FAK-Akt signaling pathway
10.1016/j.canlet.2018.05.004 · 2018 · External reference
Platelet-endothelial cell adhesion molecule-1 (CD31) recycles and induces cell growth inhibition on human tumor cell lines
10.1002/jcb.20769 · 2006 · External reference
CD31 immunohistochemical staining in Kaposi Sarcoma
10.5858/arpa.2012-0153-le · 2012 · External reference
RGDS peptide induces caspase 8 and caspase 9 activation in human endothelial cells
10.1182/blood-2003-06-2144 · 2004 · External reference
Role of NRP-1 in VEGF-VEGFR2-Independent Tumorigenesis
10.1007/s11523-016-0422-0 · 2016 · External reference
The RGD story: a personal account
10.1016/s0945-053x(03)00083-0 · 2003 · External reference
Tumor-penetrating peptides
10.3389/fonc.2013.00216 · 2013 · External reference
Heteromultivalent targeting of integrin alphavbeta3 and neuropilin 1 promotes cell survival via the activation of the IGF-1/insulin receptors
10.1016/j.biomaterials.2017.10.042 · 2018 · External reference
