Research graph
References from Testing Amyloid Cross-Toxicity in the Vertebrate Brain. Local targets link to admitted publications; unresolved targets remain external evidence.
Cell-to-Cell Transmission of Pathogenic Proteins in Neurodegenerative Disease
10.1038/nm.3457 · 2014 · External reference
Cellular Milieu Imparts Distinct Pathological α-Synuclein Strains in α-Synucleinopathies
10.1038/s41586-018-0104-4 · 2018 · External reference
Pathogenic Protein Seeding in Alzheimer Disease and Other Neurodegenerative Disorders
10.1002/ana.22615 · 2011 · External reference
Prion-like Mechanisms in Alzheimer Disease
10.1016/b978-0-444-63945-5.00016-7 · 2018 · External reference
Prion-like Seeding and Nucleation of Intracellular Amyloid-β
10.1016/j.nbd.2018.01.015 · 2018 · External reference
Attempt to Untangle the Prion-Like Misfolding Mechanism for Neurodegenerative Diseases
10.3390/ijms19103081 · 2018 · External reference
Distinct Differences in Prion-like Seeding and Aggregation between Tau Protein Variants Provide Mechanistic Insights into Tauopathies
10.1074/jbc.m117.815357 · 2018 · External reference
What Is the Evidence That Tau Pathology Spreads through Prion-like Propagation?
10.1186/s40478-017-0488-7 · 2017 · External reference
Targeting Prion-like Protein Spreading in Neurodegenerative Diseases
10.4103/1673-5374.239433 · 2018 · External reference
Prion-Like Characteristics of Polyglutamine-Containing Proteins
10.1101/cshperspect.a024257 · 2018 · External reference
Protein Misfolding Detected Early in Pathogenesis of Transgenic Mouse Model of Huntington Disease Using Amyloid Seeding Assay
10.1074/jbc.m111.305417 · 2012 · External reference
Secondary Nucleation in Amyloid Formation
10.1039/c8cc02204f · 2018 · External reference
The Evidence for the Spread and Seeding Capacities of the Mutant Huntingtin Protein in in Vitro Systems and Their Therapeutic Implications
10.3389/fnins.2017.00647 · 2017 · External reference
Rapid Dissemination of Alpha-Synuclein Seeds through Neural Circuits in an in-Vivo Prion-like Seeding Experiment
10.1186/s40478-018-0587-0 · 2018 · External reference
TDP-43 Is Intercellularly Transmitted across Axon Terminals
10.1083/jcb.201504057 · 2015 · External reference
Seeding and Propagation of Lesions in Neurodegenerative Diseases: A New Paradigm
2015 · External reference
Protein Transmission, Seeding and Degradation: Key Steps for α-Synuclein Prion-Like Propagation
10.5607/en.2014.23.4.324 · 2014 · External reference
Multiphysics of Prionlike Diseases: Progression and Atrophy
10.1103/physrevlett.121.158101 · 2018 · External reference
Cross-Interactions between the Alzheimer Disease Amyloid-β Peptide and Other Amyloid Proteins: A Further Aspect of the Amyloid Cascade Hypothesis
10.1074/jbc.r116.714576 · 2016 · External reference
The Era of Neurodegenerative Metastasis
10.1021/acschemneuro.9b00371 · 2019 · External reference
Interactions of Pathological Proteins in Neurodegenerative Diseases
10.1007/s00401-017-1709-7 · 2017 · External reference
Updated TDP-43 in Alzheimer’s Disease Staging Scheme
10.1007/s00401-016-1537-1 · 2016 · External reference
Alzheimer Disease with Amygdala Lewy Bodies: A Distinct Form of α-Synucleinopathy
10.1097/01.jnen.0000225908.90052.07 · 2006 · External reference
Neuropathological and Genetic Correlates of Survival and Dementia Onset in Synucleinopathies: A Retrospective Analysis
10.1016/s1474-4422(16)30291-5 · 2017 · External reference
TDP-43 Pathology in Alzheimer’s Disease, Dementia with Lewy Bodies and Ageing
10.1111/bpa.12424 · 2017 · External reference
Performance on the Dementia Rating Scle in Parkinson’s Disease with Dementia and Dementia with Lewy Bodies: Comparison with Progressive Supranuclear Palsy and Alzheimer’s Disease
10.1136/jnnp.74.9.1215 · 2003 · External reference
The Sydney Multicenter Study of Parkinson’s Disease: The Inevitability of Dementia at 20 Years
10.1002/mds.21956 · 2008 · External reference
Overlap between Parkinson Disease and Alzheimer Disease in ABCA7 Functional Variants
10.1212/nxg.0000000000000044 · 2016 · External reference
Updated TDP-43 in Alzheimer’s Disease Staging Scheme
10.1007/s00401-016-1537-1 · 2016 · External reference
Regional Overlap of Pathologies in Lewy Body Disorders
10.1093/jnen/nlx002 · 2017 · External reference
Genome-Wide Association Studies in Alzheimer’s Disease: A Review
10.1007/s11910-013-0381-0 · 2013 · External reference
Apolipoprotein E. and Alzheimer Disease: Risk, Mechanisms and Therapy
10.1038/nrneurol.2012.263 · 2013 · External reference
Alzheimer’s and Parkinson’s Diseases: The Prion Concept in Relation to Assembled A, Tau, and -Synuclein
10.1126/science.1255555 · 2015 · External reference
Initiation and Synergistic Fibrillization of Tau and Alpha-Synuclein
10.1126/science.1082324 · 2003 · External reference
Tau Enhances α-Synuclein Aggregation and Toxicity in Cellular Models of Synucleinopathy
10.1371/journal.pone.0026609 · 2011 · External reference
Neuropathology, Biochemistry, and Biophysics of?-Synuclein Aggregation
10.1111/j.1471-4159.2007.04764.x · 2007 · External reference
A Powerful Yeast Model to Investigate the Synergistic Interaction of α-Synuclein and Tau in Neurodegeneration
10.1371/journal.pone.0055848 · 2013 · External reference
10.1186/alzrt109 · 2012 · Admitted local publication
Alpha-Synuclein in Lewy Body Disease and Alzheimer’s Disease
10.1111/j.1750-3639.1999.tb00552.x · 1999 · External reference
Ubiquitylation of Synphilin-1 and -Synuclein by SIAH and Its Presence in Cellular Inclusions and Lewy Bodies Imply a Role in Parkinson’s Disease
10.1073/pnas.0401081101 · 2004 · External reference
α-Synuclein Ubiquitination and Novel Therapeutic Targets for Parkinson’s Disease
10.2174/18715273113126660195 · 2014 · External reference
Nitrosative Stress in the ER: A New Role for S -Nitrosylation in Neurodegenerative Diseases
10.1021/cb600244c · 2006 · External reference
Emerging Role of Protein-Protein Transnitrosylation in Cell Signaling Pathways
10.1089/ars.2012.4703 · 2013 · External reference
Aberrant Protein S-Nitrosylation Contributes to the Pathophysiology of Neurodegenerative Diseases
10.1016/j.nbd.2015.03.017 · 2015 · External reference
S-Nitrosylation of the Thioredoxin-like Domains of Protein Disulfide Isomerase and Its Role in Neurodegenerative Conditions
10.3389/fchem.2015.00027 · 2015 · External reference
Preparing Synthetic Ab in Different Aggregation States
2011 · External reference
Cortical Iron Regulation and Inflammatory Response in Alzheimer’s Disease and APPSWE/PS1ΔE9 Mice: A Histological Perspective
10.3389/fnins.2015.00255 · 2015 · External reference
Unresolved reference
2004 · External reference
