Research graph
References from 1,4-Dideoxy-1,4-imino- d -arabinitol (DAB) Analogues Possessing a Hydrazide Imide Moiety as Potent and Selective α-Mannosidase Inhibitors. Local targets link to admitted publications; unresolved targets remain external evidence.
Glycosidase inhibition: assessing mimicry of the transition state
10.1039/b915870g · 2010 · External reference
Glycosidase inhibitors: update and perspectives on practical use
10.1093/glycob/cwg090 · 2003 · External reference
Imino sugars and glycosyl hydrolases
10.1016/b978-0-12-385518-3.00004-3 · 2011 · External reference
Review: Miglitol has potential as a therapeutic drug against obesity
10.1186/s12986-015-0048-8 · 2015 · External reference
A review of Gaucher disease pathophysiology, clinical presentation and treatments
10.3390/ijms18020441 · 2017 · External reference
Migalastat for the treatment of Fabry disease
10.1080/21678707.2018.1469978 · 2018 · External reference
Sugar-mimic glycosidase inhibitors: natural occurrence, biological activity and prospects for therapeutic application
10.1016/s0957-4166(00)00113-0 · 2000 · External reference
ToP-DNJ, a selective inhibitor of endoplasmic reticulum α-glucosidase II exhibiting antiflaviviral activity
10.1021/acschembio.7b00870 · 2017 · External reference
Naturally occurring iminosugars and related compounds: structure, distribution, and biological activity
10.2174/1568026033452438 · 2003 · External reference
C-Branched Imino sugars: Synthesis and biological relevance
10.1002/ejoc.201900605 · 2019 · External reference
Recent insights into inhibition, structure, and mechanism of configuration-retaining glycosidases
10.1002/(sici)1521-3773(19990315)38:6<750::aid-anie750>3.0.co;2-6 · 1999 · External reference
Recent developments of transition-state analogue glycosidase inhibitors of non-natural product origin
10.1021/cr000433k · 2002 · External reference
Positive attitude, shape, flexibility, added-value accessories or “just being different”: how to attract a glycosidase
10.1039/9781849737173-00120 · 2013 · External reference
Isofagomine, a potent, new glycosidase inhibitor
10.1002/anie.199417781 · 1994 · External reference
Direct observation of the protonation state of an imino sugar glycosidase inhibitor upon binding
10.1021/ja034917k · 2003 · External reference
Potent, broad-spectrum inhibition of glycosidases by an amidine derivative of D-glucose
10.1021/ja00172a045 · 1990 · External reference
Analysis of PUGNAc and NAG-thiazoline as Transition State Analogues for Human O-GlcNAcase: Mechanistic and Structural Insights into Inhibitor Selectivity and Transition State Poise
10.1021/ja065697o · 2007 · External reference
An isofagomine analogue with an amidine at the pseudoanomeric position
10.1021/ol200942g · 2011 · External reference
Jack bean α-mannosidase: Amino acid sequencing and N-glycosylation analysis of a valuable glycomics tool
10.1093/glycob/cwt106 · 2014 · External reference
Glycosidase inhibitors: structure, activity, synthesis, and medical relevance
10.1016/b978-044451967-2/00100-8 · 2007 · External reference
Glycosidase inhibitors: versatile tools in glycobiology
2012 · External reference
3,4-Dihydroxypyrrolidine as glycosidase inhibitor
10.2174/156802609787354315 · 2009 · External reference
Use of dihydroxyacetone phosphate-dependent aldolases in the synthesis of deoxy aza sugars
10.1021/jo00022a013 · 1991 · External reference
Synthesis and evaluation of homoaza sugars as glycosidase inhibitors
10.1021/jo00111a007 · 1995 · External reference
Structure-Guided Minimalist Redesign of the L-fuculose-1-phosphate aldolase active site: Expedient synthesis of novel polyhydroxylated pyrrolizidines and their inhibitory properties against glycosidases and intestinal disaccharidases
10.1002/chem.201000714 · 2010 · External reference
Inhibitor versus chaperone behaviour of d-fagomine, DAB and LAB sp2-iminosugar conjugates against glycosidases: A structure–activity relationship study in Gaucher fibroblasts
10.1016/j.ejmech.2015.08.038 · 2016 · External reference
Sugar hydrazide imides: a new family of glycosidase inhibitors
10.1039/c7ob01673e · 2017 · External reference
Bicyclic 1-azafagomine derivatives: synthesis and glycosidase inhibitory testing
10.1055/s-0039-1690019 · 2019 · External reference
Synthesis of a glucose-derived tetrazole as a new β-glucosidase inhibitor: A new synthesis of 1-deoxynojirimycin
10.1002/hlca.19910740839 · 1991 · External reference
A new synthesis of (2S,3R,4R)-2-(hydroxymethyl)pyrrolidine-3,4-diol
10.1002/hlca.19910740222 · 1991 · External reference
Synthesis of uronic-noeurostegine -a potent bacterial β-glucuronidase inhibitor
10.1039/c1ob06038d · 2011 · External reference
One-pot reductive monoalkylation of nitro aryls with hydrogen over Pd/C
10.1016/j.tetlet.2007.12.030 · 2008 · External reference
Novel Pd/C-catalyzed redox reactions between aliphatic secondary alcohols and ketones under hydrogenation conditions: application to H-D exchange reaction and the mechanistic study
10.1021/jo062582u · 2007 · External reference
Carbohydrates: potential sweet tools against cancer
10.2174/0929867325666180719114150 · 2020 · External reference
Mimicking the glucosidase transition state: shape/charge considerations
10.1021/ja00023a078 · 1991 · External reference
1-Azafagomine: A hydroxyhexahydropyridazine that potently inhibits enzymatic glycoside cleavage
10.1002/chem.19970030616 · 1997 · External reference
A simple graphical method for determining the inhibition constants of mixed, uncompetitive and non-competitive inhibitors
10.1042/bj1370143 · 1974 · External reference
Optimization of equilibrium geometries and transition structures
10.1002/jcc.540030212 · 1982 · External reference
Becke’s three parameter hybrid method using the LYP correlation functional
10.1063/1.464913 · 1993 · External reference
Development of the Colle-Salvetti correlation-energy formula into a functional of the electron density
10.1103/physrevb.37.785 · 1988 · External reference
Natural hybrid orbitals
10.1021/ja00544a007 · 1980 · External reference
An approach to computing electrostatic charges for molecules
10.1002/jcc.540050204 · 1984 · External reference
Atomic charges derived from electrostatic potentials: A detailed study
10.1002/jcc.540080616 · 1987 · External reference
Determining atom-centered monopoles from molecular electrostatic potentials. The need for high sampling density in formamide conformational analysis
10.1002/jcc.540110311 · 1990 · External reference
Fitting molecular electrostatic potentials from quantum mechanical calculations
10.1021/ct600295n · 2007 · External reference
