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References from Ropivacaine Prevents the Activation of the NLRP3 Inflammasome Caused by High Glucose in HUVECs. Local targets link to admitted publications; unresolved targets remain external evidence.
Cardiovascular disease and type 2 diabetes: has the dawn of a new era arrived?
10.2337/dc16-2736 · 2017 · External reference
Diabetes, endothelial dysfunction, and vascular repair: what should a diabetologist keep his eye on?
10.1155/2015/848272 · 2015 · External reference
Diabetes mellitus: the linkage between oxidative stress, inflammation, hypercoagulability and vascular complications
10.1016/j.jdiacomp.2015.12.018 · 2016 · External reference
Glycated collagen I induces premature senescence-like phenotypic changes in endothelial cells
10.1161/01.res.0000022161.42655.98 · 2002 · External reference
Endothelial dysfunction in diabetes
10.1038/sj.bjp.0703393 · 2000 · External reference
Oxymatrine ameliorates diabetesinduced aortic endothelial dysfunction via the regulation of eNOS and NOX4. Journal of cellular biochemistry
10.1002/jcb.28006 · 2019 · External reference
A Protective Role of Paeoniflorin in Fluctuant Hyperglycemia-Induced Vascular Endothelial Injuries through Antioxidative and Anti-Inflammatory Effects and Reduction of PKCβ1
10.1155/2019/5647219 · 2019 · External reference
Thioredoxin-interacting protein mediates high glucose-induced reactive oxygen species generation by mitochondria and the NADPH oxidase, Nox4, in mesangial cells
10.1074/jbc.m112.419101 · 2013 · External reference
Inhibition of the inflammasome NLRP3 by arglabin attenuates inflammation, protects pancreatic β-cells from apoptosis, and prevents type 2 diabetes mellitus development in ApoE2Ki mice on a chronic high-fat diet
10.1124/jpet.116.232934 · 2016 · External reference
NLRP3 inflammasome is expressed and regulated in human islets
10.1038/s41419-018-0764-x · 2018 · External reference
Inflammasome activation and IL-1β and IL-18 processing during infection
10.1016/j.it.2011.01.003 · 2011 · External reference
Toll-like receptors, the NLRP3 inflammasome, and interleukin-1β in the development and progression of type 1 diabetes
10.1038/pr.2012.24 · 2012 · External reference
Humanin prevents high glucose-induced monocyte adhesion to endothelial cells by targeting KLF2
10.1016/j.molimm.2018.07.008 · 2018 · External reference
MicroRNA-9 inhibits NLRP3 inflammasome activation in human atherosclerosis inflammation cell models through the JAK1/STAT signaling pathway
10.1159/000470822 · 2017 · External reference
Rosuvastatin alleviates diabetic cardiomyopathy by inhibiting NLRP3 inflammasome and MAPK pathways in a type 2 diabetes rat model
10.1007/s10557-013-6498-1 · 2014 · External reference
Thrombomodulin domain 1 ameliorates diabetic nephropathy in mice via anti-NF-κB/NLRP3 inflammasome-mediated inflammation, enhancement of NRF2 antioxidant activity and inhibition of apoptosis
10.1007/s00125-013-3115-6 · 2014 · External reference
Local Anesthetics: Review of Pharmacological Considerations
10.2344/0003-3006-59.2.90 · 2012 · External reference
Chondrotoxic Effects of Local Anesthetics on Human Knee Articular Cartilage-A Systematic Review
10.1002/pmrj.12007 · 2019 · External reference
Sympatholytic and Anti-Inflammatory Effects of Ropivacaine and Bupivacaine After Infraclavicular Block in Arterio Venous Fistula Surgery
10.5812/aapm.85704 · 2019 · External reference
Anti-Inflammatory Effect of Local Anaesthetic Ropivacaine in Lipopolysaccharide-Stimulated RAW264. 7 Macrophages
10.1159/000496425 · 2019 · External reference
Sirt1 modulates premature senescence-like phenotype in human endothelial cells
10.1016/j.yjmcc.2007.08.008 · 2007 · External reference
Negative regulation of NLRP3 inflammasome by SIRT1 in vascular endothelial cells
10.1016/j.imbio.2016.11.002 · 2017 · External reference
Trimethylamine N-oxide induces inflammation and endothelial dysfunction in human umbilical vein endothelial cells via activating ROS-TXNIP-NLRP3 inflammasome
10.1016/j.bbrc.2016.11.017 · 2016 · External reference
Ultrasound guided peritubal infiltration of 0.25% ropivacaine for postoperative pain relief in percutaneous nephrolithotomy
10.4103/0019-5049.135040 · 2014 · External reference
Molecular events on tooth socket healing in diabetic rabbits
10.1016/j.bjoms.2013.08.014 · 2013 · External reference
Endothelial dysfunction in diabetes mellitus
1998 · External reference
High serum interleukin-18 concentrations in patients with coronary artery disease and type 2 diabetes mellitus
2005 · External reference
IL-1β is upregulated in the diabetic retina and retinal vessels: cell-specific effect of high glucose and IL-1β autostimulation
10.1371/journal.pone.0036949 · 2012 · External reference
MicroRNA-126 suppresses inflammation in endothelial cells under hyperglycemic condition by targeting HMGB1
10.1016/j.vph.2016.12.002 · 2017 · External reference
Ropivacaine Causes Inflammation and Apoptosis in Human Umbilical Vein Endothelial Cells and Human Placental Trophoblasts
10.1055/s-0038-1675498 · 2018 · External reference
Endothelial Barrier Protection by Local AnestheticsRopivacaine and Lidocaine Block Tumor Necrosis Factor-α–induced Endothelial Cell Src Activation
10.1097/aln.0000000000000174 · 2014 · External reference
Oxidative stress-mediated HMGB1 biology
10.3389/fphys.2015.00093 · 2015 · External reference
Thioredoxin interacting protein (TXNIP) induces inflammation through chromatin modification in retinal capillary endothelial cells under diabetic conditions
10.1002/jcp.21852 · 2009 · External reference
MicroRNA-106 attenuates hyperglycemia-induced vascular endothelial cell dysfunction by targeting HMGB1
10.1016/j.gene.2018.07.063 · 2018 · External reference
Ilexgenin A inhibits endoplasmic reticulum stress and ameliorates endothelial dysfunction via suppression of TXNIP/NLRP3 inflammasome activation in an AMPK dependent manner
10.1016/j.phrs.2015.05.012 · 2015 · External reference