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References from Oral Bioavailability Comparison of Artemisinin, Deoxyartemisinin, and 10-Deoxoartemisinin Based on Computer Simulations and Pharmacokinetics in Rats. Local targets link to admitted publications; unresolved targets remain external evidence.
Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings
10.1016/s0169-409x(96)00423-1 · 1997 · External reference
Comprehensive assessment of ADMET risks in drug discovery
10.2174/138161209788682514 · 2009 · External reference
Reducing the risk of drug attrition associated with physicochemical properties
10.1016/s0065-7743(10)45024-1 · 2010 · External reference
Artemisinin-based combination therapies for uncomplicated malaria
10.5694/j.1326-5377.2005.tb06650.x · 2005 · External reference
The mode of action of the antimalarial artemisinin and its derivatives
10.1016/0306-3623(95)02047-0 · 1996 · External reference
Phytochemical analysis and geographic assessment of flavonoids, coumarins and sesquiterpenes in Artemisia annua L. based on HPLC-DAD quantification and LC-ESI-QTOF-MS/MS confirmation
10.1016/j.foodchem.2019.126070 · 2020 · External reference
Quality evaluation of the artemisinin-producing plant Artemisia annua L. based on simultaneous quantification of artemisinin and six synergistic components and hierarchical cluster analysis
10.1016/j.indcrop.2018.03.043 · 2018 · External reference
Determination of artemisinin,arteannuin B and artemisinic acid in Herba Artemisiae Annuae by HPLC-UV-ELSD
2007 · External reference
Studies on the Constituents of Artemisia annua Part I
1981 · External reference
Flavonoids casticin and chrysosplenol D from Artemisia annua L. inhibit inflammation in vitro and in vivo
10.1016/j.taap.2015.04.005 · 2015 · External reference
Casticin alleviates lipopolysaccharide-induced inflammatory responses and expression of mucus and extracellular matrix in human airway epithelial cells through Nrf2/Keap1 and NF-kappaB pathways
10.1002/ptr.6067 · 2018 · External reference
Studies on anti-heat-stress activity and its mechanisms of total coumarins from Artemisia annua
2009 · External reference
Qualitative–(semi) quantitative data acquisition of artemisinin and its metabolites in rat plasma using an LTQ/Orbitrap mass spectrometer
10.1002/jms.2958 · 2012 · External reference
Rapid identification of phase I and II metabolites of artemisinin antimalarials using LTQ-Orbitrap hybrid mass spectrometer in combination with online hydrogen/deuterium exchange technique
10.1002/jms.1943 · 2011 · External reference
Artemisia annua L.: evidence of sesquiterpene lactones’ fraction antinociceptive activity
10.1186/1472-6882-14-266 · 2014 · External reference
Synthesis and antimalarial activity of (+)-deoxoartemisinin
10.1021/jm00167a036 · 1990 · External reference
A short and stereospecific synthesis of (+)-deoxoartemisinin and (−)-deoxodesoxyartemisinin
10.1016/s0040-4039(01)93831-6 · 1989 · External reference
NMR studies on novel antitumor drug candidates, deoxoartemisinin and carboxypropyldeoxoartemisinin
10.1006/bbrc.2000.3086 · 2000 · External reference
Antiangiogenic activity of deoxoartemisinin derivatives on chorioallantoic membrane
10.1016/j.bmcl.2005.11.074 · 2006 · External reference
Antitumor activity of novel deoxoartemisinin monomers, dimers, and trimer
10.1021/jm020119d · 2003 · External reference
Artemisinins: Artemisinin, Dihydroartemisinin, Artemether and Artesunate
10.1007/978-3-0346-0480-2_9 · 2011 · External reference
Differential effects of orally versus parenterally administered qinghaosu derivative artemether in dogs
10.1016/s0940-2993(99)80128-6 · 1999 · External reference
In vitro erythrocytic uptake studies of artemisinin and selected derivatives using lc–ms and 2d-qsar analysis of uptake in parasitized erythrocytes
10.1016/j.bmc.2009.05.026 · 2009 · External reference
Quantification of dihydroartemisinin, artesunate and artemisinin in human blood: overcoming the technical challenge of protecting the peroxide bridge
10.4155/bio.11.158 · 2011 · External reference
Comparison of in vitro/in vivo blood distribution and pharmacokinetics of artemisinin,artemether and dihydroartemisinin in rats
10.1016/j.jpba.2018.09.024 · 2019 · External reference
Rapid identification of phase I and II metabolites of artemisinin antimalarials using LTQ-Orbitrap hybrid mass spectrometer in combination with online hydrogen/deuterium exchange technique
10.1002/jms.1943 · 2011 · External reference
Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings
10.1016/s0169-409x(00)00129-0 · 2001 · External reference
Unresolved reference
2012 · External reference
Absorption prediction from physicochemical parameters
10.1016/s1461-5347(99)00188-1 · 1999 · External reference
Brain Swelling and Death in Children with Cerebral Malaria
10.1056/nejmoa1400116 · 2015 · External reference
Synthesis of novel 10-deoxoartemisinins
10.1016/j.bmcl.2005.03.050 · 2005 · External reference
Evaluation of Microbial Transformation of 10-deoxoartemisinin by UPLC-ESI-Q-TOF-MS(E)
10.3390/molecules24213874 · 2019 · External reference
Mechanistic approaches to predicting oral drug absorption
10.1208/s12248-009-9098-z · 2009 · External reference
Modelling and simulation in drug absorption processes
10.1080/00498250701502114 · 2007 · External reference
Why is it challenging to predict intestinal drug absorption and oral bioavailability in human using rat model
10.1007/s11095-006-9041-2 · 2006 · External reference
Impact of physiological, physicochemical and biopharmaceutical factors in absorption and metabolism mechanisms on the drug oral bioavailability of rats and humans
10.1517/17425255.3.4.469 · 2007 · External reference
Determination of artemisinin, arteannuin B and artemisinic acid in Herba Artemisiae Annuae by HPLC-UV-ELSD
2007 · External reference
Effects of arteannuin B, arteannuic acid and scopoletin on pharmacokinetics of artemisinin in mice
10.1016/j.apjtm.2016.05.004 · 2016 · External reference
Design, docking study and ADME prediction of Isatin derivatives as anti-HIV agents
10.1007/s00044-010-9329-y · 2011 · External reference
Virtual screening, ADME study, and molecular dynamic simulation of chalcone and flavone derivatives as 5-Lipoxygenase (5-LO) inhibitor
10.1080/08927022.2020.1732961 · 2020 · External reference
Unresolved reference
2010 · External reference
Unresolved reference
External reference
Unresolved reference
External reference
LC-ESI-MS/MS analysis and pharmacokinetics of plantainoside D isolated from Chirita longgangensis var. hongyao, a potential anti-hypertensive active component in rats
10.3390/molecules190915103 · 2014 · External reference
Application of a sensitive and specific LC-MS/MS method for determination of eriodictyol-8-C-β-d-glucopyranoside in rat plasma for a bioavailability study
10.1002/bmc.3263 · 2015 · External reference
Quantification and pharmacokinetics of crizotinib in rats by liquid chromatography–tandem mass spectrometry
10.1002/bmc.3636 · 2016 · External reference
Population pharmacokinetic properties of artemisinin in healthy male Vietnamese volunteers
10.1186/s12936-016-1134-8 · 2016 · External reference
