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References from Discovery of Novel Peptides as DPP-IV Inhibitors: <i>In Silico</i> Screening, Molecular Dynamics Simulations, and Preliminary <i>In Vitro</i> Evaluation. Local targets link to admitted publications; unresolved targets remain external evidence.
Epidemiology of Obesity and Diabetes and Their Cardiovascular Complications
10.1161/circresaha.115.306825 · 2016 · External reference
The Importance of Physical Activity in the Prevention of Type II Diabetes, Hypertension and Obesity
10.17719/jisr.20153813713 · 2015 · External reference
GLP-1 Receptor Agonists
10.1056/nejmra2500106 · 2026 · External reference
Expression of the GLP-1 Receptor in Mouse, Rat, and Human Pancreas
10.1369/jhc.2008.951319 · 2008 · External reference
GLP-1 Inhibits and Adrenaline Stimulates Glucagon Release by Differential Modulation of N- and L-Type Ca2+ Channel-Dependent Exocytosis
10.1016/j.cmet.2010.04.007 · 2010 · External reference
Glucagon-like Peptide-1 (GLP-1) Analogs: Recent Advances, New Possibilities, and Therapeutic Implications
10.1021/jm500810s · 2015 · External reference
High Potency Antagonists of the Pancreatic Glucagon-like Peptide-1 Receptor
10.1074/jbc.272.34.21201 · 1997 · External reference
Cardiovascular, Mortality, and Kidney Outcomes with GLP-1 Receptor Agonists in Patients with Type 2 Diabetes: A Systematic Review and Meta-Analysis of Cardiovascular Outcome Trials
10.1016/s2213-8587(19)30249-9 · 2019 · External reference
Identification of the DPP-IV Inhibitory Peptides from Donkey Blood and Regulatory Effect on the Gut Microbiota of Type 2 Diabetic Mice
10.3390/foods11142148 · 2022 · External reference
In Silico Analysis of Novel Dipeptidyl Peptidase-IV Inhibitory Peptides Released from Macadamia Integrifolia Antimicrobial Protein 2 (MiAMP2) and the Possible Pathways Involved in Diabetes Protection
10.1016/j.crfs.2021.08.008 · 2021 · External reference
Mechanisms of Action and Therapeutic Application of Glucagon-like Peptide-1
10.1016/j.cmet.2018.03.001 · 2018 · External reference
Peptide Therapeutics from Venom: Current Status and Potential
10.1016/j.bmc.2017.09.029 · 2018 · External reference
Inhibitor Selectivity in the Clinical Application of Dipeptidyl Peptidase-4 Inhibition
10.1042/cs20090047 · 2010 · External reference
Insight into Structure Activity Relationship of DPP-4 Inhibitors for Development of Antidiabetic Agents
10.3390/molecules28155860 · 2023 · External reference
Cryo-EM Structure of the Activated GLP-1 Receptor in Complex with a G Protein
10.1038/nature22394 · 2017 · External reference
ADMET Profiling and Molecular Docking of Potential Antimicrobial Peptides Previously Isolated from African Catfish, Clarias Gariepinus
10.3389/fmolb.2022.1039286 · 2022 · External reference
Correlation between Stability of a Protein and Its Dipeptide Composition: A Novel Approach for Predicting in Vivo Stability of a Protein from Its Primary Sequence
10.1093/protein/4.2.155 · 1990 · External reference
Permeation Enhancer Decorated Nanoparticles for Oral Delivery of Insulin: Manipulating the Surface Density of Borneol and PEG for Absorption Barriers
10.1039/d4bm01210k · 2025 · External reference
Systemic Delivery of Peptides by the Oral Route: Formulation and Medicinal Chemistry Approaches
10.1016/j.addr.2020.05.007 · 2020 · External reference
Protein Identification and Analysis Tools on the ExPASy Server
10.1385/1-59259-890-0:571 · 2005 · External reference
The Glucagon-like Peptides: A Double-Edged Therapeutic Sword?
10.1016/s0165-6147(03)00160-3 · 2003 · External reference
The Structure and Function of the Glucagon-like Peptide-1 Receptor and Its Ligands
10.1111/j.1476-5381.2011.01687.x · 2012 · External reference
Identification and in Silico Study of a Novel Dipeptidyl Peptidase IV Inhibitory Peptide Derived from Green Seaweed Ulva Spp. Hydrolysates
10.1016/j.lwt.2021.112738 · 2022 · External reference
Computational Screening for the Dipeptidyl Peptidase-IV Inhibitory Peptides from Putative Hemp Seed Hydrolyzed Peptidome as a Potential Antidiabetic Agent
10.3390/ijms25115730 · 2024 · External reference
Dipeptidyl Peptidase IV Inhibitory Peptides from Chickpea Proteins (Cicer Arietinum L.): Pharmacokinetics, Molecular Interactions, and Multi-Bioactivities
10.3390/ph16081109 · 2023 · External reference
Distal Mutation V486M Disrupts the Catalytic Activity of DPP4 by Affecting the Flap of the Propeller Domain
10.1038/s41401-021-00818-x · 2022 · External reference
Comparative Molecular Dynamics Reveal Ligand-Dependent Structural and Dynamic Determinants of Dipeptidyl Peptidase IV Recognition and Inhibition
10.1080/07391102.2026.2673422 · 2026 · External reference
Soybean- and Lupin-Derived Peptides Inhibit DPP-IV Activity on In Situ Human Intestinal Caco-2 Cells and Ex Vivo Human Serum
10.3390/nu10081082 · 2018 · External reference
Tenebrio Molitor Proteins-Derived DPP-4 Inhibitory Peptides: Preparation, Identification, and Molecular Binding Mechanism
10.3390/foods11223626 · 2022 · External reference
Systemic Delivery of Peptides by the Oral Route: Formulation and Medicinal Chemistry Approaches
10.1016/j.addr.2020.05.007 · ExternalCitation · doi-reference
Peptide Therapeutics from Venom: Current Status and Potential
10.1016/j.bmc.2017.09.029 · ExternalCitation · doi-reference
GLP-1 Inhibits and Adrenaline Stimulates Glucagon Release by Differential Modulation of N- and L-Type Ca2+ Channel-Dependent Exocytosis
10.1016/j.cmet.2010.04.007 · ExternalCitation · doi-reference
Mechanisms of Action and Therapeutic Application of Glucagon-like Peptide-1
10.1016/j.cmet.2018.03.001 · ExternalCitation · doi-reference
In Silico Analysis of Novel Dipeptidyl Peptidase-IV Inhibitory Peptides Released from Macadamia Integrifolia Antimicrobial Protein 2 (MiAMP2) and the Possible Pathways Involved in Diabetes Protection
10.1016/j.crfs.2021.08.008 · ExternalCitation · doi-reference
Identification and in Silico Study of a Novel Dipeptidyl Peptidase IV Inhibitory Peptide Derived from Green Seaweed Ulva Spp. Hydrolysates
10.1016/j.lwt.2021.112738 · ExternalCitation · doi-reference
The Glucagon-like Peptides: A Double-Edged Therapeutic Sword?
10.1016/s0165-6147(03)00160-3 · ExternalCitation · doi-reference
Cardiovascular, Mortality, and Kidney Outcomes with GLP-1 Receptor Agonists in Patients with Type 2 Diabetes: A Systematic Review and Meta-Analysis of Cardiovascular Outcome Trials
10.1016/s2213-8587(19)30249-9 · ExternalCitation · doi-reference
Glucagon-like Peptide-1 (GLP-1) Analogs: Recent Advances, New Possibilities, and Therapeutic Implications
10.1021/jm500810s · ExternalCitation · doi-reference
Cryo-EM Structure of the Activated GLP-1 Receptor in Complex with a G Protein
10.1038/nature22394 · ExternalCitation · doi-reference
Distal Mutation V486M Disrupts the Catalytic Activity of DPP4 by Affecting the Flap of the Propeller Domain
10.1038/s41401-021-00818-x · ExternalCitation · doi-reference
Permeation Enhancer Decorated Nanoparticles for Oral Delivery of Insulin: Manipulating the Surface Density of Borneol and PEG for Absorption Barriers
10.1039/d4bm01210k · ExternalCitation · doi-reference
Inhibitor Selectivity in the Clinical Application of Dipeptidyl Peptidase-4 Inhibition
10.1042/cs20090047 · ExternalCitation · doi-reference
GLP-1 Receptor Agonists
10.1056/nejmra2500106 · ExternalCitation · doi-reference
High Potency Antagonists of the Pancreatic Glucagon-like Peptide-1 Receptor
10.1074/jbc.272.34.21201 · ExternalCitation · doi-reference
Comparative Molecular Dynamics Reveal Ligand-Dependent Structural and Dynamic Determinants of Dipeptidyl Peptidase IV Recognition and Inhibition
10.1080/07391102.2026.2673422 · ExternalCitation · doi-reference
Correlation between Stability of a Protein and Its Dipeptide Composition: A Novel Approach for Predicting in Vivo Stability of a Protein from Its Primary Sequence
10.1093/protein/4.2.155 · ExternalCitation · doi-reference
The Structure and Function of the Glucagon-like Peptide-1 Receptor and Its Ligands
10.1111/j.1476-5381.2011.01687.x · ExternalCitation · doi-reference
Epidemiology of Obesity and Diabetes and Their Cardiovascular Complications
10.1161/circresaha.115.306825 · ExternalCitation · doi-reference
Expression of the GLP-1 Receptor in Mouse, Rat, and Human Pancreas
10.1369/jhc.2008.951319 · ExternalCitation · doi-reference
Protein Identification and Analysis Tools on the ExPASy Server
10.1385/1-59259-890-0:571 · ExternalCitation · doi-reference
The Importance of Physical Activity in the Prevention of Type II Diabetes, Hypertension and Obesity
10.17719/jisr.20153813713 · ExternalCitation · doi-reference
ADMET Profiling and Molecular Docking of Potential Antimicrobial Peptides Previously Isolated from African Catfish, Clarias Gariepinus
10.3389/fmolb.2022.1039286 · ExternalCitation · doi-reference
Identification of the DPP-IV Inhibitory Peptides from Donkey Blood and Regulatory Effect on the Gut Microbiota of Type 2 Diabetic Mice
10.3390/foods11142148 · ExternalCitation · doi-reference
Tenebrio Molitor Proteins-Derived DPP-4 Inhibitory Peptides: Preparation, Identification, and Molecular Binding Mechanism
10.3390/foods11223626 · ExternalCitation · doi-reference
Computational Screening for the Dipeptidyl Peptidase-IV Inhibitory Peptides from Putative Hemp Seed Hydrolyzed Peptidome as a Potential Antidiabetic Agent
10.3390/ijms25115730 · ExternalCitation · doi-reference
Insight into Structure Activity Relationship of DPP-4 Inhibitors for Development of Antidiabetic Agents
10.3390/molecules28155860 · ExternalCitation · doi-reference
Soybean- and Lupin-Derived Peptides Inhibit DPP-IV Activity on In Situ Human Intestinal Caco-2 Cells and Ex Vivo Human Serum
10.3390/nu10081082 · ExternalCitation · doi-reference
Dipeptidyl Peptidase IV Inhibitory Peptides from Chickpea Proteins (Cicer Arietinum L.): Pharmacokinetics, Molecular Interactions, and Multi-Bioactivities
10.3390/ph16081109 · ExternalCitation · doi-reference
