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References from Aryl-Alkyl-Lysines Interact with Anionic Lipid Components of Bacterial Cell Envelope Eliciting Anti-Inflammatory and Antibiofilm Properties. Local targets link to admitted publications; unresolved targets remain external evidence.
Unresolved reference
External reference
Antibiotics in the clinical pipeline at the end of 2015
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Membrane-Active Small Molecules: Designs Inspired by Antimicrobial Peptides
10.1002/cmdc.201500299 · 2015 · External reference
Antimicrobial peptidomimetics: reinterpreting nature to deliver innovative therapeutics
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Detergent-like properties of magainin antibiotic peptides: a 31P solid-state NMR spectroscopy study
10.1016/j.bbamem.2005.03.003 · 2005 · External reference
Histidine-rich designer peptides of the LAH4 family promote cell delivery of a multitude of cargo
10.1002/psc.2955 · 2017 · External reference
Rational Design of α-Helical Antimicrobial Peptides with Enhanced Activities and Specificity/Therapeutic Index
10.1074/jbc.m413406200 · 2005 · External reference
Erratum: Non-haemolytic β-amino-acid oligomers
10.1038/35012704 · 2000 · External reference
De Novo Design of Antibacterial β-Peptides
10.1021/ja992728p · 1999 · External reference
Improved antimicrobial peptides based on acyl-lysine oligomers
10.1038/nbt1309 · 2007 · External reference
N,N’-Linked Oligoureas as Foldamers: Chain Length Requirements for Helix Formation in Protic Solvent Investigated by Circular Dichroism, NMR Spectroscopy, and Molecular Dynamics
10.1021/ja044392b · 2005 · External reference
Non-hemolytic α-AApeptides as antimicrobial peptidomimetics
10.1039/c1cc13684d · 2011 · External reference
De novo design and in vivo activity of conformationally restrained antimicrobial arylamide foldamers
10.1073/pnas.0811818106 · 2009 · External reference
Tuning the hemolytic and antibacterial activities of amphiphilic polynorbornene derivatives
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Amphiphilic polymethacrylate derivatives as antimicrobial agents
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Biocidal activity of polystyrenes that are cationic by virtue of protonation
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Biodegradable nanostructures with selective lysis of microbial membranes
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Polymeric coatings that inactivate both influenza virus and pathogenic bacteria
10.1073/pnas.0608803103 · 2006 · External reference
Polymers with tunable side-chain amphiphilicity as non-hemolytic antibacterial agents
10.1039/c3cc43751e · 2013 · External reference
Antibacterial and hemolytic activities of pyridinium polymers as a function of the spatial relationship between the positive charge and the pendant alkyl tail
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Synthetic antimicrobial peptidomimetics with therapeutic potential
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Designing Simple Lipidated Lysines: Bifurcation Imparts Selective Antibacterial Activity
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L-Lysine based lipidated biphenyls as agents with anti-biofilm and anti-inflammatory properties that also inhibit intracellular bacteria
10.1039/c7cc04206j · 2017 · External reference
Fatty Acid Comprising Lysine Conjugates: Anti-MRSA Agents That Display In Vivo Efficacy by Disrupting Biofilms with No Resistance Development
10.1021/acs.bioconjchem.7b00055 · 2017 · External reference
Unresolved reference
2006 · External reference
Unresolved reference
1976 · External reference
High-Field Dynamic Nuclear Polarization for Solid and Solution Biological NMR
10.1007/s00723-008-0129-1 · 2008 · External reference
High frequency dynamic nuclear polarization
10.1021/ar300348n · 2013 · External reference
Characterization of membrane protein function by solid-state NMR spectroscopy
10.1016/j.sbi.2014.03.009 · 2014 · External reference
The structure of fibrils from ’misfolded’ proteins
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Nuclear magnetic resonance (NMR) applied to membrane–protein complexes
10.1017/s003358351600010x · 2016 · External reference
The structural and topological analysis of membrane-associated polypeptides by oriented solid-state NMR spectroscopy: Established concepts and novel developments
10.1016/j.bpc.2010.11.002 · 2011 · External reference
The membrane interactions of antimicrobial peptides revealed by solid-state NMR spectroscopy
10.1016/j.chemphyslip.2012.01.009 · 2012 · External reference
Small molecular antibacterial peptoid mimics: the simpler the better!
10.1021/jm401680a · 2014 · External reference
Aryl-alkyl-lysines: Membrane-Active Small Molecules Active against Murine Model of Burn Infection
10.1021/acsinfecdis.5b00092 · 2016 · External reference
Aryl-Alkyl-Lysines: Agents That Kill Planktonic Cells, Persister Cells, Biofilms of MRSA and Protect Mice from Skin-Infection
10.1371/journal.pone.0144094 · 2015 · External reference
Antiviral Screening of Multiple Compounds against Ebola Virus
10.3390/v8110277 · 2016 · External reference
Aryl-alkyl-lysines: small molecular membrane-active antiplasmodial agents
10.1039/c6md00589f · 2017 · External reference
Aryl-alkyl-lysines: Membrane-Active Fungicides That Act against Biofilms of Candida albicans
10.1021/acsinfecdis.6b00192 · 2017 · External reference
Lipid conformation in model membranes and biological membranes
10.1017/s0033583500000305 · 1980 · External reference
The description of membrane lipid conformation, order and dynamics by 2H-NMR
10.1016/0304-4157(83)90015-1 · 1983 · External reference
Deuterium magnetic resonance: theory and application to lipid membranes
10.1017/s0033583500002948 · 1977 · External reference
pH-Dependent Membrane Interactions of the Histidine-Rich Cell-Penetrating Peptide LAH4-L1
10.1016/j.bpj.2017.06.053 · 2017 · External reference
The immunopathogenesis of sepsis
10.1038/nature01326 · 2002 · External reference
Toll-like receptors in the induction of the innate immune response
10.1038/35021228 · 2000 · External reference
Surviving sepsis in the era of antibiotic resistance: are there any alternative approaches to antibiotic therapy?
10.1016/j.micpath.2015.02.001 · 2015 · External reference
Lipopolysaccharide Neutralization by Cationic-Amphiphilic Polymers through Pseudoaggregate Formation
10.1021/acs.biomac.5b01567 · 2016 · External reference
Impact of LL-37 on anti-infective immunity
10.1189/jlb.0704380 · 2005 · External reference
Potential of immunomodulatory host defense peptides as novel anti-infectives
10.1016/j.tibtech.2009.07.004 · 2009 · External reference
Effect of the Hydrophobicity to Net Positive Charge Ratio on Antibacterial and Anti-Endotoxin Activities of Structurally Similar Antimicrobial Peptides
10.1021/bi900724x · 2010 · External reference
Short Syntheticβ-Sheet Forming Peptide Amphiphiles as Broad Spectrum Antimicrobials with Antibiofilm and Endotoxin Neutralizing Capabilities
10.1002/adfm.201202850 · 2013 · External reference
Biofilms: an emergent form of bacterial life
10.1038/nrmicro.2016.94 · 2016 · External reference
Bacterial biofilms: from the natural environment to infectious diseases
10.1038/nrmicro821 · 2004 · External reference
Pel is a cationic exopolysaccharide that cross-links extracellular DNA in thePseudomonas aeruginosa biofilm matrix
10.1073/pnas.1503058112 · 2015 · External reference
Biofilm Matrix Proteins
10.1128/microbiolspec.mb-0004-2014 · 2015 · External reference
Extracellular matrix-associated proteins form an integral and dynamic system during Pseudomonas aeruginosa biofilm development
10.3389/fcimb.2015.00040 · 2015 · External reference
Identification of proteins associated with the Pseudomonas aeruginosa biofilm extracellular matrix
10.1021/pr300395j · 2012 · External reference
Proteome Profiles of Outer Membrane Vesicles and Extracellular Matrix of Pseudomonas aeruginosa Biofilms
10.1021/acs.jproteome.5b00312 · 2015 · External reference
Influence of O polysaccharides on biofilm development and outer membrane vesicle biogenesis in Pseudomonas aeruginosa PAO1
10.1128/jb.01463-13 · 2014 · External reference
Outer-membrane vesicles from Gram-negative bacteria: biogenesis and functions
10.1038/nrmicro3525 · 2015 · External reference
l-Lysine based lipidated biphenyls as agents with anti-biofilm and anti-inflammatory properties that also inhibit intracellular bacteria
10.1039/c7cc04206j · 2017 · External reference
Bicelles: a model membrane system for all seasons?
10.1016/s0969-2126(98)00123-3 · 1998 · External reference
Biphenyl phosphatidylcholine: a promoter of liposome deformation and bicelle collective orientation by magnetic fields
10.1016/j.plipres.2010.02.002 · 2010 · External reference
31 P NMR First Spectral Moment Study of the Partial Magnetic Orientation of Phospholipid Membranes
10.1016/s0006-3495(99)76940-7 · 1999 · External reference
Solid-State NMR Studies of Antimicrobial Peptide Interactions with Specific Lipid Environments
10.1039/9781782627449-00287 · 2014 · External reference
From Nanodiscs to Isotropic Bicelles: A Procedure for Solution Nuclear Magnetic Resonance Studies of Detergent-Sensitive Integral Membrane Proteins
10.1016/j.str.2016.07.017 · 2016 · External reference
Secondary Structure and Lipid Contact of A Peptide Antibiotic In Phospholipid Bilayers By REDOR
10.1529/biophysj.103.032706 · 2004 · External reference
Membrane perturbing activities and structural properties of the frog-skin derived peptide Esculentin-1a(1-21)NH 2 and its Diastereomer Esc(1-21)-1c: Correlation with their antipseudomonal and cytotoxic activity
10.1016/j.bbamem.2017.09.009 · 2017 · External reference
Solution and Solid-State Nuclear Magnetic Resonance Structural Investigations of the Antimicrobial Designer Peptide GL13K in Membranes
10.1021/acs.biochem.7b00526 · 2017 · External reference
Unresolved reference
External reference
Action of melittin on the DPPC-cholesterol liquid-ordered phase: a solid state 2H-and 31P-NMR study
10.1016/s0006-3495(95)80272-9 · 1995 · External reference
Biphenyl phosphatidylcholine: a promoter of liposome deformation and bicelle collective orientation by magnetic fields
10.1016/j.plipres.2010.02.002 · 2010 · External reference
