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References from Phthalimide Derivatives with Bioactivity against Plasmodium falciparum : Synthesis, Evaluation, and Computational Studies Involving bc 1 Cytochrome Inhibition. Local targets link to admitted publications; unresolved targets remain external evidence.
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Recent Advances in Malaria Drug Discovery
10.1016/j.bmcl.2013.03.067 · 2013 · External reference
A Molecular Marker of Artemisinin-Resistant Plasmodium falciparum Malaria
10.1038/nature12876 · 2014 · External reference
New Molecular Targets and Strategies for Antimalarial Discovery
10.2174/0929867324666170830103003 · 2017 · External reference
Comprehensive Review on Various Strategies for Antimalarial Drug Discovery
10.1016/j.ejmech.2016.11.025 · 2017 · External reference
From Crystal to Compound: Structure-Based Antimalarial Drug Discovery
10.1042/bj20140240 · 2014 · External reference
Synthesis and Antimalarial Activity of New Atovaquone Derivatives
10.1016/j.ejmech.2009.07.021 · 2009 · External reference
Probing binding determinants in center P of the cytochrome bc1 complex using novel hydroxy-naphthoquinones
10.1016/j.bbabio.2009.07.010 · 2010 · External reference
Site of action of the antimalarial hydroxynaphthoquinone, 2-[trans-4-(4’-chlorophenyl) cyclohexyl]-3- hydroxy-1,4-naphthoquinone (566C80)
10.1016/0006-2952(92)90213-3 · 1992 · External reference
Inhibiting Plasmodium cytochrome bc1: a complex issue
10.1016/j.cbpa.2010.05.005 · 2010 · External reference
Atovaquone Derivatives as Potent Cytotoxic and Apoptosis Inducing Agents
10.1016/j.bmcl.2009.07.044 · 2009 · External reference
Specific Role of Mitochondrial Electron Transport in Blood-Stage Plasmodium falciparum
10.1038/nature05572 · 2007 · External reference
Resistance Mutations Reveal the Atovaquone-Binding Domain of Cytochrome b in Malaria Parasites
10.1046/j.1365-2958.1999.01515.x · 1999 · External reference
Clinical Atovaquone-Proguanil Resistance of Plasmodium falciparum Associated with Cytochrome b Codon 268 Mutations
10.1016/j.micinf.2006.07.011 · 2006 · External reference
Identification, Design and Biological Evaluation of Bisaryl Quinolones Targeting Plasmodium falciparum Type II NADH:Quinone Oxidoreductase (PfNDH2)
10.1021/jm201179h · 2012 · External reference
Acridinediones: Selective and Potent Inhibitors of the Malaria Parasite Mitochondrial bc1 Complex
10.1124/mol.108.045120 · 2008 · External reference
Fragment-Based Approaches in Drug Discovery and Chemical Biology
10.1021/bi3005126 · 2012 · External reference
Dual FluorescentN-Aryl-2,3- naphthalimides: Applications in Ratiometric DNA Detection and White Organic Light-Emitting Devices
10.1021/ol101760m · 2010 · External reference
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1984 · External reference
Microwave-Assisted Synthesis and Structure-Activity Relationships of Neuroactive Pyrazolo[3,4-b]Pyrrolo[3,4-d]Pyridine Derivatives
10.1016/j.bmcl.2009.11.038 · 2010 · External reference
Broadening the Chemical Scope of Laccases: Selective Deprotection of N-benzyl groups
10.1039/c5gc00525f · 2015 · External reference
Simple and Inexpensive Fluorescence-Based Technique for High-Throughput Antimalarial Drug Screening
10.1128/aac.48.5.1803-1806.2004 · 2004 · External reference
Rapid colorimetric assay for cell growth and survival
10.1016/0022-1759(86)90368-6 · 1986 · External reference
Assessment of the Pharmacodynamic Properties of Antimalarial Drugs In Vivo
10.1128/aac.41.7.1413 · 1997 · External reference
Human Disease-related Mutations in CytochromebStudied in Yeast
10.1074/jbc.m313866200 · 2004 · External reference
Structural Analysis of Atovaquone-Inhibited Cytochrome bc1 Complex Reveals the Molecular Basis of Antimalarial Drug Action
10.1038/ncomms5029 · 2014 · External reference
Structure of Complex III with Bound Cytochromecin Reduced State and Definition of a Minimal Core Interface for Electron Transfer
10.1074/jbc.m710126200 · 2008 · External reference
Development and validation of a genetic algorithm for flexible docking 1 1Edited by F. E. Cohen
10.1006/jmbi.1996.0897 · 1997 · External reference
Comparative Assessment of Scoring Functions on an Updated Benchmark: 2. Evaluation Methods and General Results
10.1021/ci500081m · 2014 · External reference
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T-coffee: a novel method for fast and accurate multiple sequence alignment 1 1Edited by J. Thornton
10.1006/jmbi.2000.4042 · 2000 · External reference
Jalview Version 2--a multiple sequence alignment editor and analysis workbench
10.1093/bioinformatics/btp033 · 2009 · External reference
Pyrrolo[3,4-c]pyridine-1,3(2H)-diones: a novel antimycobacterial class targeting mycobacterial respiration
10.1021/acs.jmedchem.5b01542 · 2015 · External reference
Synthesis and Pharmacological Evaluation of Novel Phenyl Sulfonamide Derivatives Designed as Modulators of Pulmonary Inflammatory Response
10.3390/molecules171214651 · 2012 · External reference
Hydroxyethylamine Based Phthalimides as New Class of Plasmepsin Hits: Design, Synthesis and Antimalarial Evaluation
10.1371/journal.pone.0139347 · 2015 · External reference
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