Research graph
References from Rapid Screen of Potential i-Motif Forming Sequences in DNA Repair Gene Promoters. Local targets link to admitted publications; unresolved targets remain external evidence.
Intramolecular Folding of Pyrimidine Oligodeoxynucleotides into an I-DNA Motif
10.1021/ja00140a001 · 1995 · External reference
A Tetrameric DNA Structure with Protonated Cytosine-Cytosine Base Pairs
10.1038/363561a0 · 1993 · External reference
An Intramolecular I-Motif: The Solution Structure and Base-Pair Opening Kinetics of d(5mCCT3CCT3ACCT3CC)
10.1006/jmbi.1998.1740 · 1998 · External reference
The I-Motif in Nucleic Acids
10.1016/s0959-440x(00)00091-9 · 2000 · External reference
Intramolecular Folding of a Fragment of the Cytosine-Rich Strand of Telomeric DNA into an i-Motif
10.1093/nar/22.9.1600 · 1994 · External reference
The Solution Structure and Internal Motions of a Fragment of the Cytidine-Rich Strand of the Human Telomere
10.1006/jmbi.2000.3613 · 2000 · External reference
Prevalence of Quadruplexes in the Human Genome
10.1093/nar/gki609 · 2005 · External reference
High-Throughput Sequencing of DNA G-Quadruplex Structures in the Human Genome
10.1038/nbt.3295 · 2015 · External reference
G-Quadruplexes in Promoters throughout the Human Genome
10.1093/nar/gkl1057 · 2007 · External reference
The Role of G-Quadruplex/i-Motif Secondary Structures as Cis-Acting Regulatory Elements
10.1351/pac-con-09-09-29 · 2010 · External reference
The I-Motif in the BCL2 P1 Promoter Forms an Unexpectedly Stable Structure with a Unique 8:5:7 Loop Folding Pattern
10.1021/ja9076292 · 2009 · External reference
I-Motif Formation in Gene Promoters: Unusually Stable Formation in Sequences Complementary to Known G-Quadruplexes
10.1039/c2cc30863k · 2012 · External reference
4 n −1 Is a “Sweet Spot” in DNA i-Motif Folding of 2′-Deoxycytidine Homopolymers
10.1021/jacs.6b10117 · 2017 · External reference
Identification of Multiple Genomic DNA Sequences Which Form I-Motif Structures at Neutral PH
10.1093/nar/gkx090 · 2017 · External reference
The Transcriptional Complex Between the BCL2 i-Motif and HnRNP LL Is a Molecular Switch for Control of Gene Expression That Can Be Modulated by Small Molecules
10.1021/ja4109352 · 2014 · External reference
The Dynamic Character of the BCL2 Promoter i-Motif Provides a Mechanism for Modulation of Gene Expression by Compounds That Bind Selectively to the Alternative DNA Hairpin Structure
10.1021/ja410934b · 2014 · External reference
Mutually Exclusive Formation of G-Quadruplex and i-Motif Is a General Phenomenon Governed by Steric Hindrance in Duplex DNA
10.1021/acs.biochem.6b00016 · 2016 · External reference
I-Motif DNA Structures Are Formed in the Nuclei of Human Cells
10.1038/s41557-018-0046-3 · 2018 · External reference
A Mechanosensor Mechanism Controls the G-Quadruplex/i-Motif Molecular Switch in the MYC Promoter NHE III1
10.1021/jacs.6b09196 · 2016 · External reference
I-Motif DNA: Structure, Stability and Targeting with Ligands
10.1016/j.bmc.2014.05.047 · 2014 · External reference
Evaluation of the Stability of DNA I-Motifs in the Nuclei of Living Mammalian Cells
10.1002/anie.201712284 · 2018 · External reference
Unraveling the 4n – 1 Rule for DNA i-Motif Stability: Base Pairs vs. Loop Lengths
10.1039/c8ob01198b · 2018 · External reference
Unusual Isothermal Hysteresis in DNA I-Motif PH Transitions: A Study of the RAD17 Promoter Sequence
10.1016/j.bpj.2018.03.012 · 2018 · External reference
Human DNA Repair Genes Possess Potential G-Quadruplex Sequences in Their Promoters and 5′-Untranslated Regions
10.1021/acs.biochem.7b01172 · 2018 · External reference
Influence of Tetra(Ethylene Glycol) (EG4) Substitution at the Loop Region on the Intramolecular DNA i-Motif
10.1021/ma300230q · 2012 · External reference
Loop Nucleotides Impact the Stability of Intrastrand I-Motif Structures at Neutral PH
10.1039/c5cp02794b · 2015 · External reference
The Importance of Loop Length on the Stability of I-Motif Structures
10.1039/c4cc07279k · 2015 · External reference
Effect of Interior Loop Length on the Thermal Stability and pKa of i-Motif DNA
10.1021/bi5014722 · 2015 · External reference
Understanding the Effect of the Nature of the Nucleobase in the Loops on the Stability of the I-Motif Structure
10.1039/c5cp07428b · 2016 · External reference
Fundamental Aspects of the Nucleic Acid I-Motif Structures
10.1039/c4ra02129k · 2014 · External reference
Thermal Difference Spectra: A Specific Signature for Nucleic Acid Structures
10.1093/nar/gni134 · 2005 · External reference
Regulation of DNA Alkylation Damage Repair: Lessons and Therapeutic Opportunities
10.1016/j.tibs.2016.10.001 · 2017 · External reference
Promoter CpG Island Hypermethylation of the DNA Repair Enzyme MGMT Predicts Clinical Response to Dacarbazine in a Phase II Study for Metastatic Colorectal Cancer
10.1158/1078-0432.ccr-12-3518 · 2013 · External reference
MGMT Expression and Promoter Methylation Status May Depend on the Site of Surgical Sample Collection within Glioblastoma: A Possible Pitfall in Stratification of Patients?
10.1007/s11060-011-0639-9 · 2012 · External reference
Cancer Epigenomics: Implications of DNA Methylation in Personalized Cancer Therapy
10.1111/j.1349-7006.2009.01095.x · 2009 · External reference
Personalized Treatment Strategies in Glioblastoma: MGMT Promoter Methylation Status
10.2147/ott.s50208 · 2013 · External reference
Clinical Relevance of MGMT in the Treatment of Cancer
10.1200/jco.2002.06.110 · 2002 · External reference
Detection of MGMT Promoter Methylation in Glioblastoma Using Pyrosequencing
2015 · External reference
Induction of MGMT Expression Is Associated with Temozolomide Resistance in Glioblastoma Xenografts
10.1215/15228517-2008-090 · 2009 · External reference
Regulation of Telomeric I-Motif Stability by 5-Methylcytosine and 5-Hydroxymethylcytosine Modification
10.1039/c4ob02646b · 2015 · External reference
Epigenetic Modification, Dehydration, and Molecular Crowding Effects on the Thermodynamics of i-Motif Structure Formation from C-Rich DNA
10.1021/bi401523b · 2014 · External reference
