Contact and support
Need help, have a question, or want to contact the ResearchHub team?
© 2026 ResearchHub. Built for responsible scholarly connection.
Privacy-aware community infrastructureResearch graph
References from Nucleobase Derivatives as Building Blocks to Form Ru(II)-Based Complexes with High Cytotoxicity. Local targets link to admitted publications; unresolved targets remain external evidence.
Metal Complexes of Uracils
10.1016/0010-8545(87)85009-9 · 1987 · External reference
On the Origin of the Canonical Nucleobases: An Assessment of Selection Pressures across Chemical and Early Biological Evolution
10.1002/ijch.201300009 · 2013 · External reference
Chapter 25 - Nucleotide Metabolism
10.1016/b978-0-12-416687-5.00025-7 · 2015 · External reference
Nucleic Acids
10.1016/b978-008055232-3.60059-5 · 2007 · External reference
5-FU Metabolism in Cancer and Orally-Administrable 5-FU Drugs
10.3390/cancers2031717 · 2010 · External reference
Phase III Multicenter Randomized Trial of Oxaliplatin Added to Chronomodulated Fluorouracil–Leucovorin as First-Line Treatment of Metastatic Colorectal Cancer
10.1200/jco.2000.18.1.136 · 2000 · External reference
Synthesis, Characterization and in Vitro Biological Assays of a Silver(I) Complex with 5-Fluorouracil: A Strategy to Overcome Multidrug Resistant Tumor Cells
10.1016/j.jfluchem.2017.01.016 · 2017 · External reference
A Ruthenium-Based 5-Fluorouracil Complex with Enhanced Cytotoxicity and Apoptosis Induction Action in HCT116 Cells
10.1038/s41598-017-18639-6 · 2018 · External reference
Arene-Ruthenium(II) Complexes Containing 5-Fluorouracil-1-Methyl Isonicotinate: Synthesis and Characterization of Their Anticancer Activity
10.1016/j.ica.2012.02.046 · 2012 · External reference
Synthesis and Crystal Structures of Tetra- and Hexanuclear Copper(I) Complexes of Pyrimidine Derivatives, [Cu4(C4H8N2S)4](ClO4)4 and [Cu6(C5H5N2S)6]
10.1016/s0020-1693(00)84961-0 · 1992 · External reference
Synthesis, Characterization and in Vitro Cytotoxicity of Homobimetallic Complexes of Palladium(II) with 2-Thiouracil Ligands. Crystal Structure of [Pd2(TU)(PPh3)3Cl2]
10.1002/aoc.1227 · 2007 · External reference
Supramolecular Architectures Based on P-Cymene/Ruthenium Complexes Functionalized with Nucleobases
10.1039/c7ce01496a · 2017 · External reference
Ruthenium Complexes: An Emerging Ground to the Development of Metallopharmaceuticals for Cancer Therapy
10.2174/1389557515666151001142012 · 2016 · External reference
Exploring Biologically Relevant Chemical Space with Metal Complexes
10.1016/j.cbpa.2007.05.013 · 2007 · External reference
Transition Metal Complexes with Bioactive Ligands: Mechanisms for Selective Ligand Release and Applications for Drug Delivery
10.1039/c4mt00069b · 2014 · External reference
Synthesis and Anticancer Activity of [RuCl2(H6-Arene)(Aroylthiourea)] Complexes─High Activity against the Human Neuroblastoma (IMR-32) Cancer Cell Line
10.1021/acsomega.9b00349 · 2019 · External reference
Ru(II) Complexes Containing Uracil Nucleobase Analogs with Cytotoxicity against Tumor Cells
10.1016/j.jinorgbio.2019.110751 · 2019 · External reference
Cytotoxic Gold(I) Complexes with Amidophosphine Ligands Containing Thiophene Moieties
10.3390/inorganics7020013 · 2019 · External reference
Ru (II) Compounds: Next-Generation Anticancer Metallotherapeutics?
10.1021/acs.jmedchem.7b01689 · 2018 · External reference
NKP-1339, the First Ruthenium-Based Anticancer Drug on the Edge to Clinical Application
10.1039/c3sc53243g · 2014 · External reference
A Ruthenium(II) Based Photosensitizer and Transferrin Complexes Enhance Photo-Physical Properties, Cell Uptake, and Photodynamic Therapy Safety and Efficacy
10.1039/c5pp00450k · 2016 · External reference
Biological Applications of Ru(II) Polypyridyl Complexes
10.1016/j.ccr.2018.02.013 · 2018 · External reference
Synthesis and In Vitro (Anticancer) Evaluation of H6-Arene Ruthenium Complexes Bearing Stannyl Ligands
10.3390/inorganics5030044 · 2017 · External reference
Anti-Proliferative and Anti-Migration Activity of Arene–Ruthenium(II) Complexes with Azole Therapeutic Agents
10.3390/inorganics6040132 · 2018 · External reference
Electrochemical and Spectroscopic Studies on RuCl2(PPh3)2(N)2 and RuCl2(PPh3)2(N–N) Complexes (N = pyridine Derivatives and N–N = phenanthroline or Bipyridine Derivatives). X-Ray Structure of RuCl2(PPh3)2(Phen)
10.1016/s0277-5387(01)00744-6 · 2001 · External reference
Ruthenium(II) Complexes of 1,3-Thiazolidine-2-Thione: Cytotoxicity against Tumor Cells and Anti-Trypanosoma Cruzi Activity Enhanced upon Combination with Benznidazole
10.1016/j.jinorgbio.2015.12.024 · 2016 · External reference
Selective Ru(II)/Lawsone Complexes Inhibiting Tumor Cell Growth by Apoptosis
10.1016/j.jinorgbio.2017.08.019 · 2017 · External reference
Ruthenium(II) Complexes of 1,3-Thiazolidine-2-Thione: Cytotoxicity against Tumor Cells and Anti-Trypanosoma Cruzi Activity Enhanced upon Combination with Benznidazole
10.1016/j.jinorgbio.2015.12.024 · 2016 · External reference
[Ag(L)NO3] Complexes with 2-Benzoylpyridine-Derived Hydrazones: Cytotoxic Activity and Interaction with Biomolecules
10.1021/acsomega.8b00533 · 2018 · External reference
Enantiomeric Amino Acid Schiff Base Copper(II) Complexes as a New Class of RNA-Targeted Metallo-Intercalators: Single X-Ray Crystal Structural Details, Comparative in Vitro DNA/RNA Binding Profile, Cleavage, and Cytotoxicity
10.1021/acsomega.9b00131 · 2019 · External reference
Polycyclic Aromatic Hydrocarbons Physically Intercalate into Duplex Regions of Denatured DNA
10.1021/bi00394a013 · 1987 · External reference
A New Rapid and Simple Non-Radioactive Assay to Monitor and Determine the Proliferation of Lymphocytes: An Alternative to [3H]Thymidine Incorporation Assay
10.1016/0022-1759(94)90396-4 · 1994 · External reference
A rapid and simple method for measuring thymocyte apoptosis by propidium iodide staining and flow cytometry
10.1016/0022-1759(91)90198-o · 1991 · External reference
