Research graph
References from Synthetic Strategy for Pyrazolo[1,5- a ]pyridine and Pyrido[1,2- b ]indazole Derivatives through AcOH and O2-Promoted Cross-dehydrogenative Coupling Reactions between 1,3-Dicarbonyl Compounds and N -Amino-2-iminopyridines. Local targets link to admitted publications; unresolved targets remain external evidence.
The Chemistry of Heterocycles: Structures, Reactions
2003 · External reference
Unresolved reference
1997 · External reference
Survey of GMP Bulk Reactions Run in a Research Facility between 1985 and 2002
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Modern advances in heterocyclic chemistry in drug discovery
10.1039/c6ob00936k · 2016 · External reference
A Comprehensive Review of N-Heterocycles as Cytotoxic Agents
10.2174/0929867323666160809093930 · 2016 · External reference
Synthesis and antiviral evaluation of some new pyrazole and fused pyrazolopyrimidine derivatives
10.1016/j.bmc.2008.06.054 · 2008 · External reference
Pyrazolone-fused combretastatins and their precursors: synthesis, cytotoxicity, antitubulin activity and molecular modeling studies
10.1016/j.bmc.2010.03.006 · 2010 · External reference
Design, synthesis and cytotoxicity studies of novel pyrazolo[1,5-a]pyridine derivatives
10.1016/j.ejmech.2016.11.037 · 2017 · External reference
Synthesis of novel ellipticine analogues and their inhibition of Moloney leukaemia reverse transcriptase
10.1016/s0960-894x(96)00521-5 · 1996 · External reference
Phosphodiesterase inhibitors. Part 6: Design, synthesis, and structure–activity relationships of PDE4-inhibitory pyrazolo[1,5-a]pyridines with anti-inflammatory activity
10.1016/j.bmcl.2013.07.069 · 2013 · External reference
Antifungal and antimycobacterial activity of new N1-[1-aryl-2-(1H-Imidazol-1-yl and 1H-1,2,4-triazol-1-yl)ethylidene]pyridine-2-carboxamidrazone derivatives: A combined experimental and computational approach
10.3998/ark.5550190.0005.521 · 2003 · External reference
Design, synthesis, and biological evaluation of pyrazolo[1,5-a]pyridine-3-carboxamides as novel antitubercular agents
10.1021/acsmedchemlett.5b00176 · 2015 · External reference
Pyrazolo[1,5-a]pyridine-3-carboxamide hybrids: Design, synthesis and evaluation of antitubercular activity
10.1016/j.ejmech.2016.09.030 · 2017 · External reference
Identification of Pyrazolo[1,5-a]pyridine-3-carboxamide Diaryl Derivatives as Drug Resistant Antituberculosis Agents
10.1021/acsmedchemlett.8b00410 · 2019 · External reference
Fused azaindole derivatives: molecular design, synthesis and In vitro pharmacology leading to the preferential dopamine D3 receptor agonist FAUC 725
10.1016/s0960-894x(02)00390-6 · 2002 · External reference
Pharmacophore-guided drug discovery investigations leading to bioactive 5-aminotetrahydropyrazolopyridines. Implications for the binding mode of heterocyclic dopamine D3 receptor agonists
10.1021/jm0503805 · 2005 · External reference
Synthesis, Radiofluorination, and In Vitro Evaluation of Pyrazolo[1,5-a]pyridine-Based Dopamine D4 Receptor Ligands: Discovery of an Inverse Agonist Radioligand for PET
10.1021/jm701375u · 2008 · External reference
Interactive SAR studies: rational discovery of super-potent and highly selective dopamine D3 receptor antagonists and partial agonists
10.1021/jm025558r · 2002 · External reference
Novel pyrazolo[1,5-a]pyridines as orally active EP1 receptor antagonists: Synthesis, structure-activity relationship studies, and biological evaluation
10.1016/j.bmc.2017.03.003 · 2017 · External reference
Pyrazolopyridine antiherpetics: SAR of C2′ and C7 amine substituents
10.1016/j.bmc.2005.01.044 · 2005 · External reference
Discovery of FR166124, a novel water-soluble pyrazolo[1,5-a]pyridine adenosine A1 receptor antagonist
10.1016/s0960-894x(99)00304-2 · 1999 · External reference
Discovery of 6-Oxo-3-(2-phenylpyrazolo[1,5-a]pyridin-3-yl)-1(6H)-pyridazinebutanoic acid (FK 838): A novel non-xanthine adenosine A1 receptor antagonist with potent diuretic activity
10.1021/jm980671w · 1999 · External reference
The identification of pyrazolo[1,5-a]pyridines as potent p38 kinase inhibitors
10.1016/j.bmcl.2008.09.040 · 2008 · External reference
Pyrazolo[1,5-a]pyridines as p38 Kinase Inhibitors
10.1021/ol0519745 · 2005 · External reference
Cp*CoIII–catalyzed alkylation of primary and secondary C(sp3)-H bonds of 8-alkylquinolines with maleimides
10.1021/acs.joc.8b02974 · 2019 · External reference
Direct functionalization of C(sp2)-H bond in nonaromatic azaheterocycles: palladium-catalyzed cross-Dehydrogenative coupling (CDC) of 2H-imidazole 1-oxides with pyrroles and thiophenes
10.1021/acsomega.8b02916 · 2019 · External reference
Metal-free regioselective cross dehydrogenative coupling of cyclic ethers and aryl carbonyls
10.1021/acs.joc.8b03048 · 2019 · External reference
Carboxylic acid-promoted single-step indole construction from simple anilines and ketones via aerobic cross-dehydrogenative coupling
10.1021/acs.joc.8b02180 · 2018 · External reference
Copper catalyzed cross-dehydrogenative coupling (CDC) reaction of 4-thiazolidinone with terminal alkyne
10.1016/j.tet.2018.10.068 · 2019 · External reference
Copper catalyzed direct aerobic double-oxidative crossdehydrogenative coupling of imidazoheterocycles with aryl acetaldehydes: an articulate approach for icarbonylation at C-3 position
10.1016/j.tet.2015.12.012 · 2016 · External reference
Oxidative cross-dehydrogenative coupling between N-aryl tetrahydroisoquinolins and 5H-oxazol-4-ones through two methodologies: copper catalysis or a metal-free strategy
10.1039/c4cc04508d · 2014 · External reference
Ruthenium(II) catalysis/noncovalent interaction synergy for cross-dehydrogenative coupling of arene carboxylic acids
10.1021/acscatal.8b03392 · 2018 · External reference
Transition metal-free cross-dehydrogenative coupling reaction of coumarins with acetonitrile or acetone
10.1021/acs.joc.8b01508 · 2018 · External reference
Metal-free visible-light-induced C-H/C-H cross-dehydrogenative-coupling of quinoxalin-2(H)-ones with simple ethers
10.1021/acssuschemeng.8b04652 · 2018 · External reference
Synthesis of 2-aryl naphthoquinones by the cross-dehydrogenative coupling involving an NHC-catalyzed endo-stetter reaction
10.1021/acs.joc.8b02931 · 2019 · External reference
Design and synthesis of imidazo/benzimidazo[1,2-c]quinazoline derivatives and evaluation of their antimicrobial activity
10.1021/acsomega.8b01592 · 2018 · External reference
N-Bromosuccinimide-induced C-H bond functionalization: An intramolecular cycloaromatization of electron withdrawing group substituted 1-biphenyl-2-ylethanone for the synthesis of 10-phenanthrenol
10.1021/acs.orglett.8b01160 · 2018 · External reference
An enantioselective cross-dehydrogenative coupling catalysis approach to substituted tetrahydropyrans
10.1021/jacs.8b03063 · 2018 · External reference
Metal-free cross-dehydrogenative coupling (CDC): molecular iodine as a versatile catalyst/reagent for CDC reactions
10.1002/asia.201801237 · 2019 · External reference
Photoredox-mediated direct cross-dehydrogenative coupling of heteroarenes and amines
10.1021/acs.orglett.8b02389 · 2018 · External reference
Visible-light-promoted C(sp3)-C(sp2) cross-dehydrogenative coupling of tertiary amine with imidazopyridine
10.1021/acs.joc.8b01433 · 2018 · External reference
Iodine-mediated cross-dehydrogenative coupling of pyrazolones and alkenes
10.1039/c8ob01645c · 2018 · External reference
Copper-catalyzed oxidative cross-dehydrogenative coupling of 2H-chromenes and terminal alkynes
10.1039/c8ob00949j · 2018 · External reference
A highly efficient copper(II)-catalyzed cross-dehydrogenative-coupling reaction of N-arylglycine esters with 2-arylimidazo[1,2-a]pyridines
10.1055/s-0036-1609845 · 2018 · External reference
Copper-catalyzed synthesis of multisubstituted indoles through tandem Ullmann-type C–N formation and cross-dehydrogenative coupling reactions
10.1021/acs.joc.8b00353 · 2018 · External reference
Cross-dehydrogenative coupling of coumarins with Csp3-H bonds using an iron–organic framework as a productive heterogeneous catalyst
10.1039/c8ra00872h · 2018 · External reference
Cobalt-catalyzed cross-dehydrogenative C(sp2)-C(sp3) coupling of oxazole/thiazole with ether or cycloalkane
10.1002/asia.201701258 · 2017 · External reference
Copper-catalyzed C(sp3)-H/C(sp3)-H cross-dehydrogenative coupling with internal oxidants: synthesis of 2-trifluoromethyl-substituted dihydropyrrol-2-ols
10.1002/anie.201707719 · 2017 · External reference
Electrochemically induced intermolecular cross-dehydrogenative C-O coupling of β-diketones and β-ketoesters with carboxylic acids
10.1021/acs.joc.8b02791 · 2019 · External reference
Atmospheric oxidative catalyst-free cross-dehydrogenative coupling of aldehydes with N-hydroxyimides
10.1016/j.tetlet.2017.03.064 · 2017 · External reference
Synthesis of α-substituted primary benzylamines through copper-catalyzed cross-dehydrogenative coupling
10.1021/acs.orglett.8b03505 · 2019 · External reference
Metal-free C(sp2)-H/N-H cross-dehydrogenative coupling of quinoxalinones with aliphatic amines under visible-light photoredox catalysis
10.1021/acs.orglett.8b03079 · 2018 · External reference
(Diacetoxyiodo)benzene-mediated transition-metal-free amination of C(sp3)-H bonds adjacent to heteroatoms with azoles: synthesis of N-alkylated azoles
10.1055/s-0037-1610293 · 2018 · External reference
Nickel catalyzed ipso-hydroxylation and Subsequent cross dehydrogenative coupling of arylboronic acids with tertiary amines: A facile access to α-phenolated tertiary amines
10.1002/adsc.201701625 · 2018 · External reference
Cu(I)-Catalyzed site selective acyloxylation of indoline using O2 as the sole oxidant
10.1002/adsc.201800040 · 2018 · External reference
Hypervalent iodine(III)-promoted metal-free S–H activation: An approach for the construction of S–S, S–N, and S–C bonds
10.1002/ejoc.201402180 · 2014 · External reference
Reusable cobalt-phthalocyanine in water: Efficient catalytic aerobic oxidative coupling of thiols to construct S–N/S–S bonds
10.1039/c7gc00401j · 2017 · External reference
Cobalt-catalyzed aerobic cross-dehydrogenative coupling of C-H and thiols in water for C-S formation
10.1021/acs.joc.7b02718 · 2018 · External reference
Metal-free iodine-catalyzed direct cross-dehydrogenative coupling (CDC) between pyrazoles and thiols
10.1039/c6qo00407e · 2016 · External reference
Copper-catalyzed and air-mediated mild cross-dehydrogenative coupling of aryl thioureas and dialkyl H-phosphonates: The synthesis of thiophosphonates
10.1021/acs.joc.8b02011 · 2018 · External reference
Manganese(III) acetylacetonate-mediated phosphorylation of enamides at room temperature
10.1002/adsc.201800585 · 2018 · External reference
Electrochemical dehydrogenative phosphorylation of alcohols for the synthesis of organophosphinates
10.1021/acs.joc.8b02882 · 2019 · External reference
Substrate activation strategies in rhodium (III)-catalyzed selective functionalization of arenes
10.1021/acs.accounts.5b00077 · 2015 · External reference
Oxidative C–H/C–H coupling reactions between two (hetero) arenes
10.1021/acs.chemrev.6b00567 · 2017 · External reference
Efficient merging of copper and photoredox catalysis for the asymmetric cross-dehydrogenativecoupling of alkynes and tetrahydroisoquinolines
10.1039/c4ob02138j · 2015 · External reference
C(sp3)–C(sp3) bond formation via copper/Brønsted acid co-catalyzed C(sp3)–H bond oxidative cross-dehydrogenative-coupling (CDC) of azaarenes
10.1039/c4gc00038b · 2014 · External reference
Oxidative cross-dehydrogenative coupling between N-aryl tetrahydroisoquinolins and 5H-oxazol-4-ones through two methodologies: copper catalysis or a metal-free strategy
10.1039/c4cc04508d · 2014 · External reference
Redox-neutral α-allylation of amines by combining palladium catalysis and visible-light photoredox catalysis
10.1002/anie.201409999 · 2015 · External reference
A highly efficient gold-catalyzed oxidative C–C coupling from C–H bonds using air as oxidant
10.1002/anie.201107605 · 2012 · External reference
Graphene-supported RuO2 nanoparticles for efficient aerobic cross-dehydrogenative coupling reaction in water
10.1021/ol3028785 · 2012 · External reference
Mechanically induced Fe(III) catalysis at room temperature: solvent-free cross-dehydrogenative coupling of 3-benzylic indoles with methylenes/indoles
10.1021/acs.joc.6b02197 · 2016 · External reference
Simple and sustainable iron-catalyzed aerobic C–H functionalization of N,N-dialkylanilines
10.1021/ja402479r · 2013 · External reference
Visible-light photoredox catalysis: aza-Henry reactions via C–H functionalization
10.1021/ja909145y · 2010 · External reference
Direct sp3 C-H acroleination of N-aryltetrahydroisoquinolines by merging photoredox catalysis with nucleophilic catalysis
10.1039/c3ob42453g · 2014 · External reference
C1-Substituted N-alkyl tetrahydroisoquinoline derivatives through V-catalyzed oxidative coupling
10.1002/cctc.201100324 · 2012 · External reference
Cobalt-catalyzed cross-dehydrogenative coupling reaction between unactivated C(sp2)-H and C(sp3)-H bonds
10.1021/acs.orglett.7b02316 · 2017 · External reference
Cyclic ethers to esters and monoesters to bis-esters with unconventional coupling partners under metal free conditions via sp3 C–H functionalization
10.1039/c4cc05050a · 2014 · External reference
Graphene oxide and rose bengal: oxidative C–H functionalisation of tertiary amines using visible light
10.1039/c1gc15865a · 2011 · External reference
Cross-coupling hydrogen evolution reaction in homogeneous solution without noble metals
10.1021/ol500534w · 2014 · External reference
No photocatalyst required-versatile, visible light mediated transformations with polyhalomethanes
10.1039/c4cc10270c · 2015 · External reference
Iodo-Bodipys as visible-light-absorbing dual-functional photoredox catalysts for preparation of highly functionalized organic compounds by formation of C–C bonds via reductive and oxidative quenching catalytic mechanisms
10.1039/c3ra43299h · 2013 · External reference
Reactivity and mechanistic insight into visible-light-induced aerobic cross-dehydrogenative coupling reaction by organophotocatalysts
10.1002/chem.201102299 · 2012 · External reference
A strategy for the synthesis of 2-aryl-3-dimethylamino- pyrazolo[3,4-c]pyridines that utilizes [4+1] cycloaddition reactions of 5-arylazo-2,3,6-trisubstituted pyridines
10.1016/j.tet.2013.10.061 · 2013 · External reference
2-Aminothiophenes as Building Blocks in Heterocyclic Synthesis: Synthesis and Antimicrobial Evaluation of a New Class of Pyrido[1,2-a]thieno[3,2-e]pyrimidine, quinoline and Pyridin-2-one Derivatives
10.1016/j.ejmech.2012.03.004 · 2012 · External reference
L-Proline catalyzed one-pot synthesis of polysubstituted pyridine system incorporating benzothiazole moiety via sustainable sonochemical approach
10.1039/c8ra07013j · 2018 · External reference
Non-concerted nucleophilic [4+1] cycloaddition of (dimethylamino)methoxycarbene to arylazonicotinates in the synthesis of a pyrazolo[3,4-c]pyridines and pyrazolo[4′,3′:4,5]pyrido[2,3-d]pyrimidines
10.1016/j.tet.2013.05.040 · 2013 · External reference
Microwave assisted synthesis in water. First one pot synthesis of a novel class of polysubstituted benzo[4,5]imidazo[1,2-b]pyridazines via intramolecular SNAr
10.1039/c5ra17313b · 2015 · External reference
An efficient ultrasonic-mediated one-pot synthesis of 2,3,6,7,9- pentaazabicyclo- [3.3.1]nonanes via a N,N-dimethylformamide dimethylacetal catalyzed Mannich-like reaction
10.1039/c6ra09210a · 2016 · External reference
Synthesis of a novel series of tricyclic dihydrofuran derivatives: discovery of 8,9-dihydrofuro[3,2-c]pyrazolo[1,5-a]pyridines as melatonin receptor (MT1/MT2) ligands
10.1021/jm200385u · 2011 · External reference
Synthesis of 2- and 2,3-substituted pyrazolo[1,5-a]pyridines: scope and mechanistic considerations of a domino direct alkynylation and cyclization of N-iminopyridinium ylides using alkenyl bromides, alkenyl iodides, and alkynes
10.1021/jo201303x · 2011 · External reference
Bicyclic melatonin receptor agonists containing a ring-junction nitrogen: Synthesis, biological evaluation, and molecular modeling of the putative bioactive conformation
10.1016/j.bmc.2005.10.042 · 2006 · External reference
Scalable sonochemical synthetic strategy for pyrazolo[1,5-a]pyridine derivatives: First catalyst free concerted [3+2] cycloaddition of alkyne and alkene derivatives to 2-imino-1H-pyridin-1-amines
10.1021/acsomega.9b00562 · 2019 · External reference
Facile assembly of H-pyrazolo[5,1,a]isoquinolines via silver triflate-catalyzed one-pot tandem reaction of 2-alkynyl-benzaldehyde, sulfonohydrazide, and ketone or aldehyde
10.1002/adsc.201000176 · 2010 · External reference
Efficient generation of biologically active H-Pyrazolo[5,1-a] isoquinolines via multicomponent reaction
10.1021/ol101988q · 2010 · External reference
Pyrazolo[1,5-a]pyridines: synthetic approaches to a novel class of antiherpetics
10.1016/j.tet.2003.02.003 · 2003 · External reference
Synthesis of pyrazolo[1,5-a]pyridines by thermal intramolecular cyclization
10.1016/j.tetlet.2013.02.078 · 2013 · External reference
Pyrido[1,2-b] indazole and its derivatives
10.1002/jhet.5570110603 · 1974 · External reference
Tryptamines, carbolines, and related compounds: part ix. the cyclization of some nitro- and azido-phenylpyridines. pyrido[1,2-b]indazole
10.1139/v61-332 · 1961 · External reference
The formation of a nitrene intermediate in the reaction of nitro compounds with ferrous oxalate
10.1016/s0040-4039(01)99261-5 · 1961 · External reference
Synthesis of pyrido[1,2-b]indazoles via aryne [3 + 2] cycloaddition with n-tosylpyridinium imides
10.1021/jo200863e · 2011 · External reference
Sustainable synthetic approach for (pyrazol-4-ylidene)pyridines by metal catalyst-free aerobic C(sp2)–C(sp3) coupling reactions between 1-amino-2-imino-pyridines and 1-aryl-5-pyrazolones
10.1021/acsomega.9b01650 · 2019 · External reference
A short history of SHELX
10.1107/s0108767307043930 · 2008 · External reference
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