References

Glioblastoma multiforme-report of 267 cases treated at a single institution

10.1016/j.surneu.2004.01.028 · 2005 · External reference

The role of radio- and chemotherapy in glioblastoma

10.1159/000085575 · 2005 · External reference

Zinc-65 imaging of rat brain tumors

2001 · External reference

ZIP4 is a novel molecular marker for glioma

10.1093/neuonc/not042 · 2013 · External reference

High metallothionein predicts poor survival in glioblastoma multiforme

10.1186/s12920-015-0137-6 · 2015 · External reference

Immunohistochemical analysis of metallothionein in astrocytic tumors in relation to tumor grade, proliferative potential, and survival

10.1002/(sici)1097-0142(19981201)83:11<2361::aid-cncr16>3.0.co;2-n · 1998 · External reference

Metallothionein Genes are Highly Expressed in Malignant Astrocytomas and Associated with Patient Survival

10.1038/s41598-019-41974-9 · 2019 · External reference

Advances in metallothionein structure and functions

10.1016/j.jtemb.2005.03.003 · 2005 · External reference

The roles of metallothioneins in carcinogenesis

10.1186/s13045-018-0645-x · 2018 · External reference

Role of metallothionein 1E in the migration and invasion of human glioma cell lines

10.3892/ijo.2012.1570 · 2012 · External reference

Metallothinein 1E Enhances Glioma Invasion through Modulation Matrix Metalloproteinases-2 and 9 in U87MG Mouse Brain Tumor Model

10.3340/jkns.2016.59.6.551 · 2016 · External reference

Investigation of chemoresistance-related genes mRNA expression for selecting anticancer agents in successful adjuvant chemotherapy for a case of recurrent glioblastoma

10.1016/0090-3019(95)00299-5 · 1995 · External reference

Metallothionein overexpression in human brain tumours

10.1007/s004010050755 · 1997 · External reference

Causes of drug resistance and novel therapeutic opportunities for the treatment of glioblastoma

10.1054/drup.1998.0062 · 1999 · External reference

Drug resistance-associated factors in primary and secondary glioblastomas and their precursor tumors

10.1023/a:1006491405010 · 2000 · External reference

Restoring wtp53 activity in HIPK2 depleted MCF7 cells by modulating metallothionein and zinc

10.1016/j.yexcr.2008.10.018 · 2009 · External reference

Zinc chelation: a metallothionein 2A’s mechanism of action involved in osteosarcoma cell death and chemotherapy resistance

10.1038/cddis.2013.405 · 2013 · External reference

A role of metallothionein-3 in radiation-induced autophagy in glioma cells

10.1038/s41598-020-58237-7 · 2020 · External reference

Growth-inhibitory factor, metallothionein-like protein, and neurodegenerative diseases

10.1159/000109547 · 1994 · External reference

A review of metallothionein isoforms and their role in pathophysiology

10.1186/1477-7819-9-54 · 2011 · External reference

Nuclear localization of metallothionein during cell proliferation and differentiation

2000 · External reference

Roles of zinc and metallothionein-3 in oxidative stress-induced lysosomal dysfunction, cell death, and autophagy in neurons and astrocytes

10.1186/1756-6606-3-30 · 2010 · External reference

Oxygen free radicals and metallothionein

10.1016/0891-5849(93)90029-t · 1993 · External reference

Hypermethylation of metallothionein-3 CpG island in gastric carcinoma

10.1093/carcin/24.1.25 · 2003 · External reference

Metallothionien 3 expression is frequently down-regulated in oesophageal squamous cell carcinoma by DNA methylation

10.1186/1476-4598-4-42 · 2005 · External reference

Metallothionein III (MT3) is a putative tumor suppressor gene that is frequently inactivated in pediatric acute myeloid leukemia by promoter hypermethylation

10.1186/1479-5876-12-182 · 2014 · External reference

Modulation of metallothionein-III mRNA content and growth rate of rat C6-glial cells by transfection with human 5-HT1D receptor genes

10.1006/bbrc.1995.2334 · 1995 · External reference

Arsenic trioxide (ATO) influences the gene expression of metallothioneins in human glioblastoma cells

10.1007/s12011-012-9431-8 · 2012 · External reference

Free zinc ions outside a narrow concentration range are toxic to a variety of cells in vitro

10.1258/ebm.2010.009258 · 2010 · External reference

Concentrations of extracellular free zinc (pZn)e in the central nervous system during simple anesthetization, ischemia and reperfusion

10.1016/j.expneurol.2005.08.030 · 2006 · External reference

Metallothioneins in human tumors and potential roles in carcinogenesis

10.1016/j.mrfmmm.2003.07.013 · 2003 · External reference

A new model for prediction of drug distribution in tumor and normal tissues: pharmacokinetics of temozolomide in glioma patients

10.1158/0008-5472.can-08-2356 · 2009 · External reference

P53 effects both the duration of G2/M arrest and the fate of temozolomide-treated human glioblastoma cells

2001 · External reference

Chk1 regulates the S phase checkpoint by coupling the physiological turnover and ionizing radiation-induced accelerated proteolysis of Cdc25A

10.1016/s1535-6108(03)00048-5 · 2003 · External reference

How to interpret LC3 immunoblotting

10.4161/auto.4600 · 2007 · External reference

Signaling events for metallothionein induction

10.1016/j.mrfmmm.2003.07.014 · 2003 · External reference

Bioactivity of metallothionein-3 correlates with its novel beta domain sequence rather than metal binding properties

10.1021/bi00014a031 · 1995 · External reference

Constitutive expression of metallothionein-III (MT-III), but not MT-I, inhibits growth when cells become zinc deficient

10.1006/taap.1995.1216 · 1995 · External reference

Zn(2+) induces apoptosis in human highly metastatic SHG-44 glioma cells, through inhibiting activity of the voltage-gated proton channel Hv1

10.1016/j.bbrc.2013.07.067 · 2013 · External reference

Potassium attenuates zinc-induced death of cultured cortical astrocytes

10.1002/glia.10313 · 2004 · External reference

Autoregulatory mechanisms of phosphorylation of checkpoint kinase 1

10.1158/0008-5472.can-12-0523 · 2012 · External reference

Conservation of the Chk1 checkpoint pathway in mammals: linkage of DNA damage to Cdk regulation through Cdc25

10.1126/science.277.5331.1497 · 1997 · External reference

Roles of Chk1 in cell biology and cancer therapy

10.1002/ijc.28226 · 2014 · External reference

The E2F-regulated gene Chk1 is highly expressed in triple-negative estrogen receptor/progesterone receptor/HER-2 breast carcinomas

10.1158/0008-5472.can-06-3545 · 2007 · External reference

Targeting the checkpoint kinase Chk1 in cancer therapy

10.4161/cc.9.2.10445 · 2010 · External reference

Regulated degradation of Chk1 by chaperone-mediated autophagy in response to DNA damage

10.1038/ncomms7823 · 2015 · External reference

Genotoxic stress targets human Chk1 for degradation by the ubiquitin-proteasome pathway

10.1016/j.molcel.2005.07.019 · 2005 · External reference

Temozolomide and treatment of malignant glioma

2000 · External reference

MGMT promoter methylation in malignant gliomas: ready for personalized medicine?

10.1038/nrneurol.2009.197 · 2010 · External reference

Mutant TP53 enhances the resistance of glioblastoma cells to temozolomide by up-regulating O(6)-methylguanine DNA-methyltransferase

10.1007/s10072-012-1257-9 · 2013 · External reference

Acquired temozolomide resistance in MGMT-deficient glioblastoma cells is associated with regulation of DNA repair by DHC2

10.1093/brain/awz202 · 2019 · External reference

Roles of the metallothionein family of proteins in the central nervous system

10.1016/s0361-9230(01)00452-x · 2001 · External reference

Engineering of metallothionein-3 neuroinhibitory activity into the inactive isoform metallothionein-1

10.1074/jbc.m205730200 · 2002 · External reference

Metallothionein in carcinogenesis and cancer chemotherapy

10.1016/0306-3623(94)90152-x · 1994 · External reference

Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method

10.1006/meth.2001.1262 · 2001 · External reference

Mitotic signaling by beta-amyloid causes neuronal death

10.1096/fasebj.13.15.2225 · 1993 · External reference

Optimal detection of apoptosis by flow cytometry depends on cell morphology

10.1002/cyto.990140807 · 1993 · External reference

A novel method for the detection of viable human pancreatic beta cells by flow cytometry using fluorophores that selectively detect labile zinc, mitochondrial membrane potential and protein thiols

10.1002/cyto.a.20560 · 2008 · External reference

Flow cytometric measurement of benzo[a]pyrene-diol-epoxide-DNA adducts in normal human peripheral lymphocytes and cultured human lung cancer cells

10.1002/(sici)1097-0320(19980401)31:4<300::aid-cyto10>3.0.co;2-u · 1998 · External reference