Research graph
References from A Convenient Conversion of Amides to Ketones. Local targets link to admitted publications; unresolved targets remain external evidence.
A Knowledge-Based Approach in Designing Combinatorial or Medicinal Chemistry Libraries for Drug Discovery. 1. A Qualitative and Quantitative Characterization of Known Drug Databases
10.1021/cc9800071 · 1999 · External reference
Analysis of the reactions used for the preparation of drug candidate molecules
10.1039/b602413k · 2006 · External reference
The Medicinal Chemist’s Toolbox: An Analysis of Reactions Used in the Pursuit of Drug Candidates
10.1021/jm200187y · 2011 · External reference
Imide- and Amide-Functionalized Polymer Semiconductors
10.1021/cr500225d · 2014 · External reference
Synthetic Polypeptides for Biomedical Applications
10.1016/j.progpolymsci.2007.05.010 · 2007 · External reference
A Retrospective Look at Anthranilic Diamide Insecticides: Discovery and Lead Optimization to Chlorantraniliprole and Cyantraniliprole
10.1002/ps.4308 · 2017 · External reference
Complex III Inhibiting Strobilurin Esters, Amides, and Carbamates as Broad-Spectrum Fungicides
2016 · External reference
Amide Bond Formation and Peptide Coupling
10.1016/j.tet.2005.08.031 · 2005 · External reference
Amide Bond Formation: Beyond the Myth of Coupling Reagents
10.1039/b701677h · 2009 · External reference
Analysis of Past and Present Synthetic Methodologies on Medicinal Chemistry: Where Have All the New Reactions Gone?
10.1021/acs.jmedchem.5b01409 · 2016 · External reference
Rethinking Amide Bond Synthesis
10.1038/nature10702 · 2011 · External reference
Key Green Chemistry Research Areas─a Perspective from Pharmaceutical Manufacturers
10.1039/b703488c · 2007 · External reference
Large-Scale Amidations in Process Chemistry: Practical Considerations for Reagent Selection and Reaction Execution
10.1021/acs.oprd.2c00005 · 2022 · External reference
Nonclassical Routes for Amide Bond Formation
10.1021/acs.chemrev.6b00237 · 2016 · External reference
Amide activation: an emerging tool for chemoselective synthesis
10.1039/c8cs00335a · 2018 · External reference
Alkyl- and Cycloalkylamine: Synthesis by Reduction of Carbonic and Carboxylic Acid Derivatives
2009 · External reference
Hydrogenation of Amides to Amines by Heterogeneous Catalysis: A Review
10.1039/d3gc04175a · 2024 · External reference
Reductive Functionalization of Amides in Synthesis and for Modification of Bioactive Compounds
10.3389/fchem.2021.655849 · 2021 · External reference
Titanium Reagents for the Alkylidenation of Carboxylic Acid and Carbonic Acid Derivatives
10.1039/b009709h · 2002 · External reference
Use of Lawesson’s Reagent in Organic Syntheses
10.1021/cr040650b · 2007 · External reference
Amidine Syntheses from Classic to Contemporary for Medicinal Lead Compounds and Natural Products
10.1002/ejoc.202500400 · 2025 · External reference
Photoinduced Remote Functionalization of Amides and Amines Using Electrophilic Nitrogen Radicals
10.1002/anie.201807941 · 2018 · External reference
Enantioselective β-C(sp3)–H Nucleophilic Tosylation of Native Amides: A Synthetic Platform for Chiral Methyl Stereocenters
10.1021/jacs.4c17267 · 2025 · External reference
Amide α,β-Dehydrogenation Using Allyl-Palladium Catalysis and a Hindered Monodentate Anilide
10.1021/jacs.5b12924 · 2016 · External reference
N-Methoxy-n-Methylamides as Effective Acylating Agents
10.1016/s0040-4039(01)91316-4 · 1981 · External reference
Sterically Controlled Pd-Catalyzed Chemoselective Ketone Synthesis via N–C Cleavage in Twisted Amides
10.1021/acs.orglett.5b02209 · 2015 · External reference
Breaking Amides using Nickel Catalysis
10.1021/acscatal.6b03277 · 2017 · External reference
Nickel-catalysed Suzuki–Miyaura coupling of amides
10.1038/nchem.2388 · 2016 · External reference
Acylative Suzuki coupling of amides: acyl-nitrogen activation via synergy of independently modifiable activating groups
10.1039/c5cc00430f · 2015 · External reference
Nickel-Catalyzed Electro-Reductive Cross-Coupling of Aliphatic N-Acyl Imides with Alkyl Halides as a Strategy for Dialkyl Ketone Synthesis: Scope and Mechanistic Investigations
10.1021/acscatal.2c03268 · 2022 · External reference
Synergistic Visible-Light Photoredox/Nickel-Catalyzed Synthesis of Aliphatic Ketones via N–C Cleavage of Imides
10.1021/acs.orglett.7b00989 · 2017 · External reference
Silyl Radical Mediated Cross-Electrophile Coupling of N-Acyl-Imides with Alkyl Bromides under Photoredox/Nickel Dual Catalysis
10.1021/acs.orglett.0c00442 · 2020 · External reference
Nickel-Catalyzed Deaminative Acylation of Activated Aliphatic Amines with Aromatic Amides via C–N Bond Activation
10.1021/acs.orglett.9b04497 · 2020 · External reference
Formal Cross-Coupling of Amines and Carboxylic Acids to Form sp3–sp2 Carbon–Carbon Bonds
10.1021/jacs.2c11563 · 2023 · External reference
Skeletal Metalation of Lactams through a Carbonyl-to-Nickel-Exchange Logic
10.1038/s41467-023-40979-3 · 2023 · External reference
Hydrogen Bonding Ability of the Amide Group
10.1021/ja00819a013 · 1974 · External reference
Protease Inhibitors: Current Status and Future Prospects
10.1021/jm990412m · 2000 · External reference
Agrochemical Lead Optimization by Scaffold Hopping
10.1002/ps.4755 · 2018 · External reference
Aryl Ketones as Novel Replacements for the C-Terminal Amide Bond of Succinyl Hydroxamate MMP Inhibitors
10.1016/s0960-894x(98)00597-6 · 1998 · External reference
Alternative Precursors to 1,4-Acyl Alkyl Biradicals: Cyclic N-Acyl-1,1-Diazenes
10.1021/ja00335a087 · 1984 · External reference
Preparation and spectral characterization of some cyclic N-acyl-1,1-diazenes
10.1021/ja00317a068 · 1984 · External reference
Synthesis of Acetylhydrazines through Chloramination Reactions of Amides and Urethanes
10.1021/ic00327a031 · 1990 · External reference
Rapid and General Amination of Aryl Boronic Acids and Esters Using O-(Diphenylphosphinyl)Hydroxylamine (DPPH)
10.1021/acs.orglett.4c03625 · 2024 · External reference
Visible-Light-Induced Nitrogen-Atom Deletion of Unactivated Secondary Amines
10.1021/jacs.5c16938 · 2026 · External reference
N-Amination of Pyrrole and Indole Heterocycles with Monochloramine (NH2Cl)
10.1021/jo035587p · 2004 · External reference
Pyridine-to-Pyridazine Skeletal Editing
10.1021/jacs.5c15601 · 2025 · External reference
An Unexpected Incident during the Manufacture of O-(Diphenylphosphinyl)hydroxylamine
10.1021/acs.oprd.1c00207 · 2021 · External reference
Preparation, Use, and Safety of O-Mesitylenesulfonylhydroxylamine
10.1021/op800264p · 2009 · External reference
Micellar Effects upon the Rates of Sn2 Reactions of Halide Ions
10.1021/j100384a046 · 1990 · External reference
Reactions in micelles of cetyltrimethylammonium hydroxide. Test of the pseudophase model for kinetics
10.1021/j150626a033 · 1981 · External reference
Sulfonyl Hydrazides as a General Redox-Neutral Platform for Radical Cross-Coupling
10.1126/science.adu6406 · 2025 · External reference
An Oxidative [2,3]-Sigmatropic Rearrangement of Allylic Hydrazides
10.1021/ja2066219 · 2011 · External reference
Diazenes. VI. Alkyldiazenes
10.1021/ja00737a025 · 1971 · External reference
Stereoselective Synthesis of Cyclobutanes by Contraction of Pyrrolidines
10.1021/jacs.1c10175 · 2021 · External reference
N-Atom Deletion in Nitrogen Heterocycles
10.1002/anie.202107356 · 2021 · External reference
Skeletal editing through direct nitrogen deletion of secondary amines
10.1038/s41586-021-03448-9 · 2021 · External reference
C(sp3)–C(sp3) bond formation through nitrogen deletion of secondary amines using O-diphenylphosphinylhydroxylamine
10.1038/s44160-024-00559-9 · 2024 · External reference
Direct studies of 1,1-diazenes. Syntheses, infrared and electronic spectra, and kinetics of the thermal decomposition of N-(2,2,6,6-tetramethylpiperidyl)nitrene and N-(2,2,5,5-tetramethylpyrrolidyl)nitrene
10.1021/ja00367a020 · 1982 · External reference
Stereoretentive Formation of Cyclobutanes from Pyrrolidines: Lessons Learned from DFT Studies of the Reaction Mechanism
10.1021/acs.joc.3c00080 · 2023 · External reference
Catalytic Alkene Carboaminations Enabled by Oxidative Proton-Coupled Electron Transfer
10.1021/jacs.5b05377 · 2015 · External reference
Catalytic Ring-Opening of Cyclic Alcohols Enabled by PCET Activation of Strong O–H Bonds
10.1021/jacs.6b06517 · 2016 · External reference
Kinetic Study of Radical Production in the Thermal Decomposition of Benzoyl Peroxide by Electron Spin Resonance Spin Trapping (Spin Counting). Rate (and Substituent Effect on the Rate) of Spin Trapping by Competitive Scavenging of Benzoyloxy Radicals with Galvinoxyl
10.1021/ja00778a053 · 1972 · External reference
Mutual Activation of Two Radical Trapping Agents: Unusual “Win–Win Synergy” of Resveratrol and TEMPO during Scavenging of Dpph• Radical in Methanol
10.1021/acs.joc.2c02080 · 2022 · External reference
Electrochemical Generation of Aryl Radicals from Organoboron Reagents Enabled by Pulsed Electrosynthesis
10.1002/anie.202406203 · 2024 · External reference
Radical-Scavenging Activity of Butylated Hydroxytoluene (BHT) and Its Metabolites
10.1016/j.chemphyslip.2004.03.005 · 2004 · External reference
Radical Philicity and Its Role in Selective Organic Transformations
10.1038/s41570-021-00284-3 · 2021 · External reference
Revealing the Mechanism of TEMPO-Hypervalent Iodine(III) Oxidation of Alcohols
10.1021/jacs.5c21609 · 2026 · External reference
A Versatile and Highly Selective Hypervalent Iodine (III)/2,2,6,6-Tetramethyl-1-Piperidinyloxyl-Mediated Oxidation of Alcohols to Carbonyl Compounds
10.1021/jo971046m · 1997 · External reference
Photoinduced Remote Functionalization of Amides and Amines Using Electrophilic Nitrogen Radicals
10.1002/anie.201807941 · ExternalCitation · doi-reference
N-Atom Deletion in Nitrogen Heterocycles
10.1002/anie.202107356 · ExternalCitation · doi-reference
Electrochemical Generation of Aryl Radicals from Organoboron Reagents Enabled by Pulsed Electrosynthesis
10.1002/anie.202406203 · ExternalCitation · doi-reference
Amidine Syntheses from Classic to Contemporary for Medicinal Lead Compounds and Natural Products
10.1002/ejoc.202500400 · ExternalCitation · doi-reference
A Retrospective Look at Anthranilic Diamide Insecticides: Discovery and Lead Optimization to Chlorantraniliprole and Cyantraniliprole
10.1002/ps.4308 · ExternalCitation · doi-reference
Agrochemical Lead Optimization by Scaffold Hopping
10.1002/ps.4755 · ExternalCitation · doi-reference
Radical-Scavenging Activity of Butylated Hydroxytoluene (BHT) and Its Metabolites
10.1016/j.chemphyslip.2004.03.005 · ExternalCitation · doi-reference
Synthetic Polypeptides for Biomedical Applications
10.1016/j.progpolymsci.2007.05.010 · ExternalCitation · doi-reference
Amide Bond Formation and Peptide Coupling
10.1016/j.tet.2005.08.031 · ExternalCitation · doi-reference
N-Methoxy-n-Methylamides as Effective Acylating Agents
10.1016/s0040-4039(01)91316-4 · ExternalCitation · doi-reference
Aryl Ketones as Novel Replacements for the C-Terminal Amide Bond of Succinyl Hydroxamate MMP Inhibitors
10.1016/s0960-894x(98)00597-6 · ExternalCitation · doi-reference
Nonclassical Routes for Amide Bond Formation
10.1021/acs.chemrev.6b00237 · ExternalCitation · doi-reference
Analysis of Past and Present Synthetic Methodologies on Medicinal Chemistry: Where Have All the New Reactions Gone?
10.1021/acs.jmedchem.5b01409 · ExternalCitation · doi-reference
Mutual Activation of Two Radical Trapping Agents: Unusual “Win–Win Synergy” of Resveratrol and TEMPO during Scavenging of Dpph• Radical in Methanol
10.1021/acs.joc.2c02080 · ExternalCitation · doi-reference
Stereoretentive Formation of Cyclobutanes from Pyrrolidines: Lessons Learned from DFT Studies of the Reaction Mechanism
10.1021/acs.joc.3c00080 · ExternalCitation · doi-reference
An Unexpected Incident during the Manufacture of O-(Diphenylphosphinyl)hydroxylamine
10.1021/acs.oprd.1c00207 · ExternalCitation · doi-reference
Large-Scale Amidations in Process Chemistry: Practical Considerations for Reagent Selection and Reaction Execution
10.1021/acs.oprd.2c00005 · ExternalCitation · doi-reference
Silyl Radical Mediated Cross-Electrophile Coupling of N-Acyl-Imides with Alkyl Bromides under Photoredox/Nickel Dual Catalysis
10.1021/acs.orglett.0c00442 · ExternalCitation · doi-reference
Rapid and General Amination of Aryl Boronic Acids and Esters Using O-(Diphenylphosphinyl)Hydroxylamine (DPPH)
10.1021/acs.orglett.4c03625 · ExternalCitation · doi-reference
Sterically Controlled Pd-Catalyzed Chemoselective Ketone Synthesis via N–C Cleavage in Twisted Amides
10.1021/acs.orglett.5b02209 · ExternalCitation · doi-reference
Synergistic Visible-Light Photoredox/Nickel-Catalyzed Synthesis of Aliphatic Ketones via N–C Cleavage of Imides
10.1021/acs.orglett.7b00989 · ExternalCitation · doi-reference
Nickel-Catalyzed Deaminative Acylation of Activated Aliphatic Amines with Aromatic Amides via C–N Bond Activation
10.1021/acs.orglett.9b04497 · ExternalCitation · doi-reference
Nickel-Catalyzed Electro-Reductive Cross-Coupling of Aliphatic N-Acyl Imides with Alkyl Halides as a Strategy for Dialkyl Ketone Synthesis: Scope and Mechanistic Investigations
10.1021/acscatal.2c03268 · ExternalCitation · doi-reference
Breaking Amides using Nickel Catalysis
10.1021/acscatal.6b03277 · ExternalCitation · doi-reference
A Knowledge-Based Approach in Designing Combinatorial or Medicinal Chemistry Libraries for Drug Discovery. 1. A Qualitative and Quantitative Characterization of Known Drug Databases
10.1021/cc9800071 · ExternalCitation · doi-reference
Use of Lawesson’s Reagent in Organic Syntheses
10.1021/cr040650b · ExternalCitation · doi-reference
Imide- and Amide-Functionalized Polymer Semiconductors
10.1021/cr500225d · ExternalCitation · doi-reference
Synthesis of Acetylhydrazines through Chloramination Reactions of Amides and Urethanes
10.1021/ic00327a031 · ExternalCitation · doi-reference
Micellar Effects upon the Rates of Sn2 Reactions of Halide Ions
10.1021/j100384a046 · ExternalCitation · doi-reference
Reactions in micelles of cetyltrimethylammonium hydroxide. Test of the pseudophase model for kinetics
10.1021/j150626a033 · ExternalCitation · doi-reference
Preparation and spectral characterization of some cyclic N-acyl-1,1-diazenes
10.1021/ja00317a068 · ExternalCitation · doi-reference
Alternative Precursors to 1,4-Acyl Alkyl Biradicals: Cyclic N-Acyl-1,1-Diazenes
10.1021/ja00335a087 · ExternalCitation · doi-reference
Direct studies of 1,1-diazenes. Syntheses, infrared and electronic spectra, and kinetics of the thermal decomposition of N-(2,2,6,6-tetramethylpiperidyl)nitrene and N-(2,2,5,5-tetramethylpyrrolidyl)nitrene
10.1021/ja00367a020 · ExternalCitation · doi-reference
Diazenes. VI. Alkyldiazenes
10.1021/ja00737a025 · ExternalCitation · doi-reference
Kinetic Study of Radical Production in the Thermal Decomposition of Benzoyl Peroxide by Electron Spin Resonance Spin Trapping (Spin Counting). Rate (and Substituent Effect on the Rate) of Spin Trapping by Competitive Scavenging of Benzoyloxy Radicals with Galvinoxyl
10.1021/ja00778a053 · ExternalCitation · doi-reference
Hydrogen Bonding Ability of the Amide Group
10.1021/ja00819a013 · ExternalCitation · doi-reference
An Oxidative [2,3]-Sigmatropic Rearrangement of Allylic Hydrazides
10.1021/ja2066219 · ExternalCitation · doi-reference
Stereoselective Synthesis of Cyclobutanes by Contraction of Pyrrolidines
10.1021/jacs.1c10175 · ExternalCitation · doi-reference
Formal Cross-Coupling of Amines and Carboxylic Acids to Form sp3–sp2 Carbon–Carbon Bonds
10.1021/jacs.2c11563 · ExternalCitation · doi-reference
Enantioselective β-C(sp3)–H Nucleophilic Tosylation of Native Amides: A Synthetic Platform for Chiral Methyl Stereocenters
10.1021/jacs.4c17267 · ExternalCitation · doi-reference
Catalytic Alkene Carboaminations Enabled by Oxidative Proton-Coupled Electron Transfer
10.1021/jacs.5b05377 · ExternalCitation · doi-reference
Amide α,β-Dehydrogenation Using Allyl-Palladium Catalysis and a Hindered Monodentate Anilide
10.1021/jacs.5b12924 · ExternalCitation · doi-reference
Pyridine-to-Pyridazine Skeletal Editing
10.1021/jacs.5c15601 · ExternalCitation · doi-reference
Visible-Light-Induced Nitrogen-Atom Deletion of Unactivated Secondary Amines
10.1021/jacs.5c16938 · ExternalCitation · doi-reference
Revealing the Mechanism of TEMPO-Hypervalent Iodine(III) Oxidation of Alcohols
10.1021/jacs.5c21609 · ExternalCitation · doi-reference
Catalytic Ring-Opening of Cyclic Alcohols Enabled by PCET Activation of Strong O–H Bonds
10.1021/jacs.6b06517 · ExternalCitation · doi-reference
The Medicinal Chemist’s Toolbox: An Analysis of Reactions Used in the Pursuit of Drug Candidates
10.1021/jm200187y · ExternalCitation · doi-reference
Protease Inhibitors: Current Status and Future Prospects
10.1021/jm990412m · ExternalCitation · doi-reference
N-Amination of Pyrrole and Indole Heterocycles with Monochloramine (NH2Cl)
10.1021/jo035587p · ExternalCitation · doi-reference
A Versatile and Highly Selective Hypervalent Iodine (III)/2,2,6,6-Tetramethyl-1-Piperidinyloxyl-Mediated Oxidation of Alcohols to Carbonyl Compounds
10.1021/jo971046m · ExternalCitation · doi-reference
Preparation, Use, and Safety of O-Mesitylenesulfonylhydroxylamine
10.1021/op800264p · ExternalCitation · doi-reference
Rethinking Amide Bond Synthesis
10.1038/nature10702 · ExternalCitation · doi-reference
Nickel-catalysed Suzuki–Miyaura coupling of amides
10.1038/nchem.2388 · ExternalCitation · doi-reference
Skeletal Metalation of Lactams through a Carbonyl-to-Nickel-Exchange Logic
10.1038/s41467-023-40979-3 · ExternalCitation · doi-reference
Radical Philicity and Its Role in Selective Organic Transformations
10.1038/s41570-021-00284-3 · ExternalCitation · doi-reference
Skeletal editing through direct nitrogen deletion of secondary amines
10.1038/s41586-021-03448-9 · ExternalCitation · doi-reference
C(sp3)–C(sp3) bond formation through nitrogen deletion of secondary amines using O-diphenylphosphinylhydroxylamine
10.1038/s44160-024-00559-9 · ExternalCitation · doi-reference
Titanium Reagents for the Alkylidenation of Carboxylic Acid and Carbonic Acid Derivatives
10.1039/b009709h · ExternalCitation · doi-reference
Analysis of the reactions used for the preparation of drug candidate molecules
10.1039/b602413k · ExternalCitation · doi-reference
Amide Bond Formation: Beyond the Myth of Coupling Reagents
10.1039/b701677h · ExternalCitation · doi-reference
Key Green Chemistry Research Areas─a Perspective from Pharmaceutical Manufacturers
10.1039/b703488c · ExternalCitation · doi-reference
Acylative Suzuki coupling of amides: acyl-nitrogen activation via synergy of independently modifiable activating groups
10.1039/c5cc00430f · ExternalCitation · doi-reference
Amide activation: an emerging tool for chemoselective synthesis
10.1039/c8cs00335a · ExternalCitation · doi-reference
Hydrogenation of Amides to Amines by Heterogeneous Catalysis: A Review
10.1039/d3gc04175a · ExternalCitation · doi-reference
Sulfonyl Hydrazides as a General Redox-Neutral Platform for Radical Cross-Coupling
10.1126/science.adu6406 · ExternalCitation · doi-reference
Reductive Functionalization of Amides in Synthesis and for Modification of Bioactive Compounds
10.3389/fchem.2021.655849 · ExternalCitation · doi-reference
