Research graph
References from Structural Basis of Cyclized C17 Precursor Recognition and Product Formation in Chlororaphen and Grimophan Biosynthesis. Local targets link to admitted publications; unresolved targets remain external evidence.
Zur Kenntnis der Terpene und ätherischen Oele
External reference
Zur Biosynthese der Terpene. III. Farnesyl-pyrophosphat und 3-Methyl-Δ3-butenyl-1-pyrophosphat, die biologischen Vorstufen des Squalens
10.1002/ange.19580702403 · 1958 · External reference
Phosphorylated intermediates in the synthesis of squalene
10.1073/pnas.44.10.998 · 1958 · External reference
Isopentenol Pyrophosphate Isomerase
10.1021/ja01514a059 · 1959 · External reference
The Isoprene Rule and the Biogenesis of Terpenic Compounds
10.1007/bf02167631 · 1953 · External reference
Odorous Compounds in Natural Waters. 2-Exo-Hydroxy-2-Methylbornane, the Major Odorous Compound Produced by Several Actinomycetes
10.1021/es60028a008 · 1969 · External reference
Biosynthesis of the Off-flavor 2-Methylisoborneol by the Myxobacterium Nannocystis exedens
10.1002/anie.200702496 · 2007 · External reference
Identification and functional analysis of genes controlling biosynthesis of 2-methylisoborneol
10.1073/pnas.0802312105 · 2008 · External reference
Biochemistry and Molecular Genetics of the Biosynthesis of the Earthy Odorant Methylisoborneol in Streptomyces coelicolor
10.1021/ja803639g · 2008 · External reference
Non-Canonical C16 Homoterpene Biosynthesis Widespread in Actinobacteria
10.1002/anie.202418613 · 2024 · External reference
Structural Revision of the C16 Sesquiterpene Hegelenether and the Mechanism of C6-Methylation in Terpene Biosynthesis
10.1002/anie.202525672 · 2026 · External reference
Octamethylbicyclo[3.2.1]octadienes from the Rhizobacterium Serratia odorifera
10.1002/anie.200905680 · 2010 · External reference
Analysis of a new cluster of genes involved in the synthesis of the unique volatile organic compound sodorifen of Serratia plymuthica 4Rx13
10.1093/femsle/fnw139 · 2016 · External reference
Sodorifen Biosynthesis in the Rhizobacterium Serratia plymuthica Involves Methylation and Cyclization of MEP-Derived Farnesyl Pyrophosphate by a SAM-Dependent C-Methyltransferase
10.1021/jacs.8b08510 · 2018 · External reference
Fragmentation and [4 + 3] Cycloaddition in Sodorifen Biosynthesis
10.1038/s41557-023-01223-z · 2023 · External reference
Widespread biosynthesis of 16-carbon terpenoids in bacteria
10.1038/s41589-023-01445-9 · 2023 · External reference
Discovery and Biosynthesis of Non-Canonical C16-Terpenoids from Pseudomonas
10.1016/j.chembiol.2024.09.002 · 2024 · External reference
Homoterpene Biosynthesis in Fungi
10.1002/anie.202517837 · 2025 · External reference
Biosynthesis of the Fully Saturated C16 Homosesquiterpene Descartane through Deprotonation with Cyclopropanation
10.1002/anie.1585472 · 2026 · External reference
Common Biosynthesis of Non-canonical C16 Terpenes through a Fragmentation-Recombination Mechanism
10.1002/anie.202408809 · 2024 · External reference
Non-canonical Biosynthesis of the Brexane-Type Bishomosesquiterpene Chlororaphen through Two Consecutive Methylation Steps in Pseudomonas chlororaphis O6 and Variovorax boronicumulans PHE5–4
10.1002/anie.202303692 · 2023 · External reference
Biosynthesis of the Non-canonical C17 Sesquiterpenoids Chlororaphen A and B from Pseudomonas chlororaphis
10.1002/anie.202412040 · 2024 · External reference
Structural basis of methylation-triggered terpene cyclization
10.1016/j.chempr.2026.102948 · 2026 · External reference
Discovery and Biosynthesis of Farnesyl Pyrophosphate-Derived Non-canonical C17 Terpenes from Pseudomonas Species
10.1021/jacs.5c21930 · 2026 · External reference
Biosynthesis of 17-Carbon Terpenoids in Bacteria
10.1021/jacs.5c15311 · 2026 · External reference
Structure of Geranyl Diphosphate C-Methyltransferase from Streptomyces coelicolor and Implications for the Mechanism of Isoprenoid Modification
10.1021/bi300109c · 2012 · External reference
Structure of 2-Methylisoborneol Synthase from Streptomyces coelicolor and Implications for the Cyclization of a Noncanonical C-Methylated Monoterpenoid Substrate
10.1021/bi201827a · 2012 · External reference
Structure and catalytic mechanism of C16 terpenoid cyclase Sp-SodS from Serratia plymuthica
10.1016/j.ijbiomac.2026.151065 · 2026 · External reference
Structural basis for cyclic terpene biosynthesis by tobacco 5-epi-aristolochene synthase
10.1126/science.277.5333.1815 · 1997 · External reference
Crystal structure of pentalenene synthase: mechanistic insights on terpenoid cyclization reactions in biology
10.1126/science.277.5333.1820 · 1997 · External reference
Mechanistic Insights from the Binding of Substrate and Carbocation Intermediate Analogues to Aristolochene Synthase
10.1021/bi400691v · 2013 · External reference
Structure of Epi-Isozizaene Synthase from Streptomyces coelicolor A3(2), a Platform for New Terpenoid Cyclization Templates
10.1021/bi902088z · 2010 · External reference
Catalytic Role of Carbonyl Oxygens and Water in Selinadiene Synthase
10.1038/s41929-022-00735-0 · 2022 · External reference
Conformational Analysis, Thermal Rearrangement and EI-MS-Fragmentation Mechanism of (1(10)E,4E,6S,7R)-Germacradien-6-ol by 13C-Labeling Experiments
10.1002/anie.201507615 · 2015 · External reference
Induced Fit Mechanism in Class I Terpene Cyclases
10.1002/anie.201403648 · 2014 · External reference
Following evolution’s lead to a single residue switch for diterpene synthase product outcome
10.1073/pnas.0611454104 · 2007 · External reference
A Single Residue Switch Converts Abietadiene Synthase into a Pimaradiene Specific Cyclase
10.1021/ja074977g · 2007 · External reference
A Functional Switch Between Asperfumene and Fusicoccadiene Synthase and Entrance to Asperfumene Biosynthesis through a Vicinal Deprotonation-Reprotonation Process
10.1002/anie.202407895 · 2024 · External reference
Simulation-Guided Engineering Enables a Functional Switch in Selinadiene Synthase toward Hydroxylation
10.1021/acscatal.4c02032 · 2024 · External reference
Zur Biosynthese der Terpene. III. Farnesyl-pyrophosphat und 3-Methyl-Δ3-butenyl-1-pyrophosphat, die biologischen Vorstufen des Squalens
10.1002/ange.19580702403 · ExternalCitation · doi-reference
Biosynthesis of the Fully Saturated C16 Homosesquiterpene Descartane through Deprotonation with Cyclopropanation
10.1002/anie.1585472 · ExternalCitation · doi-reference
Biosynthesis of the Off-flavor 2-Methylisoborneol by the Myxobacterium Nannocystis exedens
10.1002/anie.200702496 · ExternalCitation · doi-reference
Octamethylbicyclo[3.2.1]octadienes from the Rhizobacterium Serratia odorifera
10.1002/anie.200905680 · ExternalCitation · doi-reference
Induced Fit Mechanism in Class I Terpene Cyclases
10.1002/anie.201403648 · ExternalCitation · doi-reference
Conformational Analysis, Thermal Rearrangement and EI-MS-Fragmentation Mechanism of (1(10)E,4E,6S,7R)-Germacradien-6-ol by 13C-Labeling Experiments
10.1002/anie.201507615 · ExternalCitation · doi-reference
Non-canonical Biosynthesis of the Brexane-Type Bishomosesquiterpene Chlororaphen through Two Consecutive Methylation Steps in Pseudomonas chlororaphis O6 and Variovorax boronicumulans PHE5–4
10.1002/anie.202303692 · ExternalCitation · doi-reference
A Functional Switch Between Asperfumene and Fusicoccadiene Synthase and Entrance to Asperfumene Biosynthesis through a Vicinal Deprotonation-Reprotonation Process
10.1002/anie.202407895 · ExternalCitation · doi-reference
Common Biosynthesis of Non-canonical C16 Terpenes through a Fragmentation-Recombination Mechanism
10.1002/anie.202408809 · ExternalCitation · doi-reference
Biosynthesis of the Non-canonical C17 Sesquiterpenoids Chlororaphen A and B from Pseudomonas chlororaphis
10.1002/anie.202412040 · ExternalCitation · doi-reference
Non-Canonical C16 Homoterpene Biosynthesis Widespread in Actinobacteria
10.1002/anie.202418613 · ExternalCitation · doi-reference
Homoterpene Biosynthesis in Fungi
10.1002/anie.202517837 · ExternalCitation · doi-reference
Structural Revision of the C16 Sesquiterpene Hegelenether and the Mechanism of C6-Methylation in Terpene Biosynthesis
10.1002/anie.202525672 · ExternalCitation · doi-reference
The Isoprene Rule and the Biogenesis of Terpenic Compounds
10.1007/bf02167631 · ExternalCitation · doi-reference
Discovery and Biosynthesis of Non-Canonical C16-Terpenoids from Pseudomonas
10.1016/j.chembiol.2024.09.002 · ExternalCitation · doi-reference
Structural basis of methylation-triggered terpene cyclization
10.1016/j.chempr.2026.102948 · ExternalCitation · doi-reference
Structure and catalytic mechanism of C16 terpenoid cyclase Sp-SodS from Serratia plymuthica
10.1016/j.ijbiomac.2026.151065 · ExternalCitation · doi-reference
Simulation-Guided Engineering Enables a Functional Switch in Selinadiene Synthase toward Hydroxylation
10.1021/acscatal.4c02032 · ExternalCitation · doi-reference
Structure of 2-Methylisoborneol Synthase from Streptomyces coelicolor and Implications for the Cyclization of a Noncanonical C-Methylated Monoterpenoid Substrate
10.1021/bi201827a · ExternalCitation · doi-reference
Structure of Geranyl Diphosphate C-Methyltransferase from Streptomyces coelicolor and Implications for the Mechanism of Isoprenoid Modification
10.1021/bi300109c · ExternalCitation · doi-reference
Mechanistic Insights from the Binding of Substrate and Carbocation Intermediate Analogues to Aristolochene Synthase
10.1021/bi400691v · ExternalCitation · doi-reference
Structure of Epi-Isozizaene Synthase from Streptomyces coelicolor A3(2), a Platform for New Terpenoid Cyclization Templates
10.1021/bi902088z · ExternalCitation · doi-reference
Odorous Compounds in Natural Waters. 2-Exo-Hydroxy-2-Methylbornane, the Major Odorous Compound Produced by Several Actinomycetes
10.1021/es60028a008 · ExternalCitation · doi-reference
Isopentenol Pyrophosphate Isomerase
10.1021/ja01514a059 · ExternalCitation · doi-reference
A Single Residue Switch Converts Abietadiene Synthase into a Pimaradiene Specific Cyclase
10.1021/ja074977g · ExternalCitation · doi-reference
Biochemistry and Molecular Genetics of the Biosynthesis of the Earthy Odorant Methylisoborneol in Streptomyces coelicolor
10.1021/ja803639g · ExternalCitation · doi-reference
Biosynthesis of 17-Carbon Terpenoids in Bacteria
10.1021/jacs.5c15311 · ExternalCitation · doi-reference
Discovery and Biosynthesis of Farnesyl Pyrophosphate-Derived Non-canonical C17 Terpenes from Pseudomonas Species
10.1021/jacs.5c21930 · ExternalCitation · doi-reference
Sodorifen Biosynthesis in the Rhizobacterium Serratia plymuthica Involves Methylation and Cyclization of MEP-Derived Farnesyl Pyrophosphate by a SAM-Dependent C-Methyltransferase
10.1021/jacs.8b08510 · ExternalCitation · doi-reference
Fragmentation and [4 + 3] Cycloaddition in Sodorifen Biosynthesis
10.1038/s41557-023-01223-z · ExternalCitation · doi-reference
Widespread biosynthesis of 16-carbon terpenoids in bacteria
10.1038/s41589-023-01445-9 · ExternalCitation · doi-reference
Catalytic Role of Carbonyl Oxygens and Water in Selinadiene Synthase
10.1038/s41929-022-00735-0 · ExternalCitation · doi-reference
Following evolution’s lead to a single residue switch for diterpene synthase product outcome
10.1073/pnas.0611454104 · ExternalCitation · doi-reference
Identification and functional analysis of genes controlling biosynthesis of 2-methylisoborneol
10.1073/pnas.0802312105 · ExternalCitation · doi-reference
Phosphorylated intermediates in the synthesis of squalene
10.1073/pnas.44.10.998 · ExternalCitation · doi-reference
Analysis of a new cluster of genes involved in the synthesis of the unique volatile organic compound sodorifen of Serratia plymuthica 4Rx13
10.1093/femsle/fnw139 · ExternalCitation · doi-reference
Structural basis for cyclic terpene biosynthesis by tobacco 5-epi-aristolochene synthase
10.1126/science.277.5333.1815 · ExternalCitation · doi-reference
Crystal structure of pentalenene synthase: mechanistic insights on terpenoid cyclization reactions in biology
10.1126/science.277.5333.1820 · ExternalCitation · doi-reference
