Contact and support
Need help, have a question, or want to contact the ResearchHub team?
© 2026 ResearchHub. Built for responsible scholarly connection.
Privacy-aware community infrastructureResearch graph
References from Inhibition of T-Cell Acute Lymphoblastic Leukemia Proliferation In Vivo by Re-expression of the p16INK4a Tumor Suppressor Gene. Local targets link to admitted publications; unresolved targets remain external evidence.
A new regulatory motif in cell-cycle control causing specific inhibition of cyclin D/CDK4
10.1038/366704a0 · 1993 · External reference
The p16INK4a/CDKN2A tumor suppressor and its relatives
1998 · External reference
Multiple tumor-suppressor gene 1 inactivation is the most frequent genetic alteration in T-cell acute lymphoblastic leukemia
10.1182/blood.v87.6.2180.bloodjournal8762180 · 1996 · External reference
Homozygous deletions of cyclin-dependent kinase inhibitor genes, p16 (INK4a) and p18, in childhood T cell lineage acute lymphoblastic leukemias
1996 · External reference
Methylation of the multi-tumor suppressor gene-2 (MTS2, CDKN1, p15INK4b) in childhood acute lymphoblastic leukemia
10.1038/sj.onc.1201428 · 1997 · External reference
Genetic studies of childhood acute lymphoblastic leukemia with emphasis on p16, MLL, and ETV6 gene abnormalities: results of St Jude Total Therapy Study XII
10.1038/sj.leu.2400779 · 1997 · External reference
Analysis of a family of cyclin-dependent kinase inhibitors: p15/MTS2/INK4b, p16/MTS1/INK4a, p18 genes in acute lymphoblastic leukemia of childhood
10.1182/blood.v86.2.755.bloodjournal862755 · 1995 · External reference
Homozygous deletion of the p16/MTS1 gene in pediatric acute lymphoblastic leukemia is associated with unfavorable clinical outcome
10.1182/blood.v89.11.4161 · 1997 · External reference
Shortened survival after relapse in T-cell acute lymphoblastic leukemia patients with p16/p15 deletions
10.1016/s0145-2126(97)00007-6 · 1997 · External reference
p15INK4b is a potential effector of TGF-beta-induced cell cycle arrest
10.1038/371257a0 · 1994 · External reference
Complex structure and regulation of the p16 (MTS1) locus
1995 · External reference
Frequent and selective methylation of p15 and deletion of both p15 and p16 in T-cell acute lymphoblastic leukemia
1997 · External reference
The INK4a tumor suppressor gene product, p19ARF, interacts with MDM2 and neutralizes MDM2's inhibition of p53
10.1016/s0092-8674(00)81400-2 · 1998 · External reference
ARF promotes Mdm2 degradation and stabilizes p53: ARF-INK4a locus deletion impairs both the Rb and p53 tumor suppressor pathways
10.1016/s0092-8674(00)81401-4 · 1998 · External reference
Functional and physical interactions of the ARF tumor suppressor with p53 and Mdm2
10.1073/pnas.95.14.8292 · 1998 · External reference
The alternative product from the human CDKN2A locus, p14ARF, participates in a regulatory feedback loop with p53 and MDM2
10.1093/emboj/17.17.5001 · 1998 · External reference
Tumor suppression at the mouse INK4a locus mediated by the alternative reading frame product p19ARF
10.1016/s0092-8674(00)80452-3 · 1997 · External reference
Genomic alterations of the p19ARF encoding exons in T-cell acute lymphoblastic leukemia
10.1182/blood.v91.3.1016 · 1998 · External reference
Autocrine growth and progression of murine X-ray-induced T cell lymphomas
10.1002/j.1460-2075.1986.tb04426.x · 1986 · External reference
Association of induction of a fully tumorigenic phenotype in murine radiation-induced T-lymphoma cells with loss of differentiation antigens, gain of CD44, and alterations in p53 protein levels
10.1002/mc.2940050305 · 1992 · External reference
Non-hereditary p53 mutations in T-cell acute lymphoblastic leukemia are associated with the relapse phase
10.1182/blood.v83.10.2922.2922 · 1994 · External reference
Dissemination and tissue invasiveness in murine acute leukemia is associated with acquisition of p53 mutation and loss of wild-type p53
10.1002/mc.2940130208 · 1995 · External reference
Radiation leukemia virus and X-irradiation induce in C57B1/6 mice two distinct T-cell neoplasms: a growth factor-dependent lymphoma and a growth factor-independent lymphoma
10.1016/0145-2126(87)90046-4 · 1987 · External reference
Monoclonal antibodies specific for simian virus 40 tumor antigens
10.1128/jvi.39.3.861-869.1981 · 1981 · External reference
A fluorescent p53GFP fusion protein facilitates its detection in mammalian cells while retaining the properties of wild-type p53
10.1038/sj.onc.1201406 · 1997 · External reference
Restoration of growth arrest by p16INK4, p21WAF1, pRB and p53 is dependent on the integrity of the endogenous cell-cycle control pathways in human glioblastoma cell lines
10.1006/excr.1997.3810 · 1998 · External reference
Transplantable myeloproliferative disease induced in mice by an interleukin 6 retrovirus
10.1084/jem.176.4.1149 · 1992 · External reference
High-titer MSCV-based retrovirus generated in the pCL acute virus packaging system confers sustained gene expression in vivo
10.1016/s0166-0934(98)00108-6 · 1998 · External reference
The pCL vector system: Rapid production of helper-free, high-titer, recombinant retroviruses
10.1128/jvi.70.8.5701-5705.1996 · 1996 · External reference
Independent induction of senescence by p16INK4a and p21CIP1 in spontaneously immortalized human fibroblasts
1998 · External reference
Reciprocal Rb inactivation and p16INK4a expression in primary lung cancers and cell lines
1995 · External reference
Absence of Cyclin D/cdk complexes in cells lacking functional retinoblastoma protein
1994 · External reference
Adenovirally transferred p16INK4/CDKN2 and p53 genes cooperate to induce apoptotic tumor cell death
10.1038/nm0397-313 · 1997 · External reference
Inactivation of the cyclin-dependent kinase inhibitor p15INK4b by deletion and de novo methylation with independence of p16INK4a alterations in murine primary T-cell lymphomas
10.1038/sj.onc.1200969 · 1997 · External reference
Disruption of the tumor suppressor gene MTS1/p16INK4a/CDKN2 by illegitimate V(D)J recombinase activity in T-cell acute lymphoblastic leukemias
10.1182/blood.v90.9.3720 · 1997 · External reference
Expression of the p16 and p15 cyclin-dependent kinase inhibitors in lymphocyte activation and neuronal differentiation
1995 · External reference
Involvement of the cyclin-dependent kinase inhibitor p16 (INK4a) in replicative senescence of normal human fibroblasts
10.1073/pnas.93.24.13742 · 1996 · External reference
An oncogenic form of p53 confers a dominant, gain-of-function phenotype that disrupts spindle checkpoint control
10.1073/pnas.95.9.5166 · 1998 · External reference
Role of the INK4a locus in tumor suppression and cell mortality
10.1016/s0092-8674(00)81079-x · 1996 · External reference
Involvement of the INK4 proteins p16 and p15 in T-lymphocyte senescence
10.1038/sj.onc.1201965 · 1998 · External reference
p16INK4a promotes differentiation and inhibits apoptosis of JKB acute lymphoblastic leukemia cells
10.1182/blood.v90.10.4106 · 1997 · External reference
Inhibition of growth of human leukemia cell lines by retrovirally expressed wild-type p16INK4a
10.1038/sj.leu.2400840 · 1997 · External reference
