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References from Sulindac Sulfide, but Not Sulindac Sulfone, Inhibits Colorectal Cancer Growth. Local targets link to admitted publications; unresolved targets remain external evidence.
Aspirin use and reduced risk of fatal colon cancer
10.1056/nejm199112053252301 · 1991 · External reference
Aspirin use and the risk for colorectal cancer and adenoma in male health professionals
10.7326/0003-4819-121-4-199408150-00001 · 1994 · External reference
Treatment of colonic and rectal adenomas with sulindac in familial adenomatous polyposis
10.1056/nejm199305063281805 · 1993 · External reference
The sulfide metabolite of sulindac prevents tumors and restores enterocyte apoptosis in a murine model of familial adenomatous polyposis
10.1093/carcin/19.1.87 · 1998 · External reference
Modulation of apoptosis by sulindac, curcumin, phenylethyl-3-methylcaffeate, and 6-phenylhexyl isothiocyanate: apoptotic index as a biomarker in colon cancer chemoprevention and promotion
1997 · External reference
Sulindac suppresses tumorigenesis in the min mouse
10.1093/carcin/17.8.1757 · 1996 · External reference
Apoptosis primarily accounts for the growth-inhibitory properties of sulindac metabolites and involves a mechanism that is independent of cyclooxygenase inhibition, cell cycle arrest, and p53 induction
1997 · External reference
Sulindac sulfone inhibits azoxymethane-induced colon carcinogenesis in rats without reducing prostaglandin levels
1997 · External reference
EGF receptor activation induces nuclear targeting of COX-2, basolateral release of prostaglandins and mitogenesis in polarizing colon cancer cells
10.1073/pnas.94.2.657 · 1997 · External reference
Regulation of eicosanoid production and mitogenesis in rat intestinal epithelial cells by transforming growth factor-α and phorbol ester
10.1172/jci116998 · 1994 · External reference
G1 delay in intestinal epithelial cells overexpressing prostaglandin endoperoxide synthase-2
1996 · External reference
Inhibition of human colon cancer cell growth by selective inhibition of cyclooxygenase-2
10.1172/jci119400 · 1997 · External reference
Demonstration that mutation of the type II transforming growth factor beta receptor inactivates its tumor suppressor activity in replication error-positive colon carcinoma cells
10.1074/jbc.270.37.22044 · 1995 · External reference
Meloxicam inhibits the growth of colorectal cancer cells
10.1093/carcin/19.12.2195 · 1998 · External reference
Altered eicosanoid levels in human colon cancer
1993 · External reference
Sulindac for polyposis of the colon
10.1002/jso.2930240119 · 1983 · External reference
Treatment of colonic and rectal adenomas with sulindac in familial adenomatous polyposis
10.1056/nejm199305063281805 · 1993 · External reference
Effects of nonsteroidal anti-inflammatory drugs on proliferation and on induction of apoptosis in colon cancer cells by a prostaglandinindependent pathway
10.1016/0006-2952(96)00181-5 · 1996 · External reference
Pharmacokinetics and dialyzability of sulindac and metabolites in patients with end-stage renal failure
10.1002/j.1552-4604.1993.tb04699.x · 1993 · External reference
Sulindac metabolism: the importance of an intact colon
10.1038/clpt.1985.192 · 1985 · External reference
Antineoplastic drugs sulindac sulfide and sulfone inhibit cell growth by inducing apoptosis
1995 · External reference
Sulfone metabolite of sulindac inhibits mammarycarcinogenesis
1997 · External reference
Sulfone metabolite of sulindac inhibits mammary carcinogenesis
1997 · External reference
Effect of restricted caloric intake on azoxymethane-induced colon tumor incidence in male F344 rats
1987 · External reference
Effect of different levels of calorie restriction on azoxymethane- induced colon carcinogenesis in male F344 rats
1990 · External reference