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References from Differentiation of Human Malignant Melanoma Cells that Escape Apoptosis After Treatment with 9-Nitrocamptothecin In Vitro. Local targets link to admitted publications; unresolved targets remain external evidence.
Chemotherapy of melanoma
1996 · External reference
Treatment for advanced melanoma
1992 · External reference
Chemotherapy for metastatic melanoma
1992 · External reference
Biology of melanocytes and melanoma
1992 · External reference
Spontaneous and induced differentiation of human melanoma cells
10.1002/ijc.2910540125 · 1993 · External reference
Differentiation of cultured human melanoma cells induced by the aromatic fatty acids phenylacetate and phenylbutyrate
10.1111/1523-1747.ep12394874 · 1994 · External reference
Inhibition of growth and induction of differentiation of metastatic melanoma cells in vitro by genistein: chemosensitivity is regulated by cellular p53
10.1038/bjc.1997.268 · 1997 · External reference
Genistein inhibits growth of B16 melanoma cells in vivo and in vitro and promotes differentiation in vitro
10.1002/(sici)1097-0215(19970904)72:5<860::aid-ijc24>3.0.co;2-b · 1997 · External reference
Cell differentiation and cell cycle alterations by tyrosine kinase inhibitors in human melanoma cells
1997 · External reference
The melanoma differentiation-associated gene mda-6, which encodes the cyclin-dependent kinase inhibitor p21, is differentially expressed during growth, differentiation and progression in human melanoma cells
1995 · External reference
Specific activation of retinoic acid receptors (RARs) and retinoid X receptors reveals a unique role for RARg in induction of differentiation and apoptosis of S91 melanoma cells
10.1074/jbc.272.30.18990 · 1997 · External reference
Antiproliferative and differentiating effects of benzodiazepine receptor ligands on B16 melanoma cells
10.1016/s0006-2952(98)00149-x · 1998 · External reference
Melanoma antigens
1992 · External reference
WAFT/CIP1 is induced in p53-mediated G1 arrest and apoptosis
1994 · External reference
DNA damage triggers a prolonged p53-dependent G1 arrest and long-term induction of Cip1 in normal human fibroblasts
10.1101/gad.8.21.2540 · 1994 · External reference
p53-dependent inhibition of cyclin-dependent kinase activities in human fibroblasts during radiation-induced G1 arrest
10.1016/0092-8674(94)90379-4 · 1994 · External reference
Effects of p21(Cip1/Waf1) at both the G1/S and the G2/M cell cycle transitions: pRb is a critical deteminant in blocking DNA replication and in preventing endoreduplication
10.1128/mcb.18.1.629 · 1998 · External reference
Nuclear accumulation of p21Cip1 at the onset of mitosis: a role at the G2/M-phase transition
10.1128/mcb.18.1.546 · 1998 · External reference
p21waf1 can block cells at two points in the cell cycle, but it does not interfere with progressive DNA-replication or stress-activated kinases
10.1038/sj.onc.1201558 · 1998 · External reference
Induction of senescent cell-derived inhibitor of DNA synthesis gene, SDI1, in hepatoblastoma (HepG2) cells arrested in the G2-phase of the cell cycle by 9-nitrocamptothecin
1995 · External reference
Resistance to apoptosis conferred by Cdk inhibitors during myocyte differentiation
10.1126/science.273.5273.359 · 1996 · External reference
Cell cycle exit upon myogenic differentiation
10.1016/s0959-437x(97)80005-6 · 1997 · External reference
Uncoupling of p21 induction and MyoD activation results in the failure of irreversible cell cycle arrest in doxorubicin-treated myocytes
10.1002/(sici)1097-4644(19970701)66:1<27::aid-jcb4>3.0.co;2-# · 1997 · External reference
The absence of p21CIP1/WAF1 alters keratinocyte growth and differentiation and promotes ras-tumor progression
10.1101/gad.10.23.3065 · 1996 · External reference
p21(WAF1/CIP1) expression is induced in newly nondividing cells in diverse epithelia and during differentiation of the Caco-2 intestinal cell line
10.1006/excr.1996.0264 · 1996 · External reference
The cyclin-dependent kinase inhibitor p21(WAF1) is required for survival of differentiating neuroblastoma cells
10.1128/mcb.16.4.1335 · 1996 · External reference
Induction of p21 (WAF1/CIP1) during differentiation
1994 · External reference
Cell cycle regulatory proteins are targets for induced differentiation of transformed cells: molecular and clinical studies employing hybrid polar compounds
10.1016/0925-5710(95)00428-9 · 1996 · External reference
p53-independent induction of p21 (WAF1/CIP1) during differentiation of HL-60 cells by tumor necrosis factor alpha
10.1016/s0925-5710(96)00540-3 · 1996 · External reference
Transcriptional activation of the Cdk inhibitor p21 by vitamin D3 leads to the induced differentiation of the myelomonocytic cell line U937
10.1101/gad.10.2.142 · 1996 · External reference
Induction of differentiation in human promyelocytic HL-60 leukemia cells activates p21, WAF1/CIP1, expression in the absence of p53
1994 · External reference
Modulation of p53, WAF1/p21 and Bcl-2 expression during retinoic acid-induced differentiation of NB4 promyelocytic cells
10.1016/s0145-2126(96)00085-9 · 1997 · External reference
Polyploidization and functional maturation are two distinct processes during megakaryocytic differentiation; involvement of cyclin-dependent kinase inhibitor p21 in polyploidization
10.1182/blood.v89.11.3980 · 1997 · External reference
The p21 cyclin-dependent kinase inhibitor suppresses tumorigenicity in vivo
10.1038/nm1095-1052 · 1995 · External reference
Inhibitory function of p21Cip/WAF1 in differentiation of primary mouse keratinocytes independent of cell cycle control
10.1126/science.280.5366.1069 · 1998 · External reference
Cell cycle gene regulation in reversibly differentiated new human hepatoma cell lines
1998 · External reference
A new regulatory motif in cell-cycle control causing specific inhibition of cyclin D/CDK4
10.1038/366704a0 · 1993 · External reference
Function of a human cyclin gene as an oncogene
10.1073/pnas.91.2.709 · 1994 · External reference
Role of the p16 tumor suppressor gene in cancer
10.1200/jco.1998.16.3.1197 · 1998 · External reference
Requirement of cyclin E-CDK2 inhibition in p16INKa-mediated growth suppression
10.1128/mcb.18.9.5284 · 1998 · External reference
Involvement of p16CDKN2A in cell cycle delays after low dose of UV irradiation
10.1016/s0027-5107(98)00174-2 · 1998 · External reference
Cancer-associated mis-sense and deletion mutations impair p16INK4 CDK inhibitory activity
10.1002/(sici)1097-0215(19960410)66:2<249::aid-ijc19>3.0.co;2-7 · 1996 · External reference
CDKN2a/p16INKa mutations and lack of p19ARF involvement in familial melanoma kindreds
10.1046/j.1523-1747.1998.00412.x · 1998 · External reference
The INK4a/ARF tumor suppressor: one gene-two products-two pathways
10.1016/s0968-0004(98)01236-5 · 1998 · External reference
The p16-cyclin D/cdk4-pRb pathway as a functional unit frequently altered in melanoma pathogenesis
1996 · External reference
Loss of expression of the p16INK4/CDKN2 gene in cutaneous malignant melanoma correlates with tumor cell proliferation and invasive stage
10.1002/(sici)1097-0215(19970620)74:3<255::aid-ijc4>3.0.co;2-y · 1997 · External reference
An analysis of p16 protein expression in sporadic malignant melanoma
10.1097/00008390-199806000-00010 · 1998 · External reference
Differential roles for cyclin-dependent kinase inhibitors p21 and p16 in the mechanisms of senescence and differentiation inhuman fibroblasts
10.1128/mcb.19.3.2109 · 1999 · External reference
Restoration of CDKN2A into melanoma cells induces morphologic changes and reduction in growth rate but not anchorage-independent growth reversal
10.1111/1523-1747.ep12276538 · 1997 · External reference
Release of cell cycle constraints in mouse melanocytes by overexpressed mutant E2FIE132, but not by deletion of p16INK4A or p21WAF1/CIP1
10.1038/sj.onc.1201773 · 1998 · External reference
Partial characterization of human leukemia U-937 cell sublines resistant to 9-nitro-camptothecin
10.1111/j.1600-0609.1994.tb00661.x · 1994 · External reference
9-Nitrocamptothecin inhibits in vitro induction of activation of the human immunodeficiency virus type (HIV-1) in latently infected human T lymphocytes
10.1089/aid.1998.14.39 · 1998 · External reference
9-Nitrocamptothecin selectively inhibits human immunodeficiency virus type 1 replication in freshly infected parental but not 9-nitrocamptothe cin-resistant U937 monocytoid cells
10.1089/088922299311411 · 1999 · External reference
The water-insoluble camptothecin analogues: promising drugs for the effective treatment of haematological malignancies
10.1016/0145-2126(95)00048-8 · 1995 · External reference
Preclinical studies of water-insoluble camptothecin congeners: cytotoxicity, development of resistance, and combination treatments
1995 · External reference
Therapeutic efficacy of camptothecin derivatives against human malignant melanoma xenografts
10.1097/00008390-199402000-00002 · 1994 · External reference
Complete inhibition of growth followed by death of human malignant melanoma cells in vitro and regression of human melanoma xenografts in immunodeficient mice induced by camptothecins
1992 · External reference
Cytotoxic efficacy of 9-nitro-camptothecin in the treatment of human malignant melanoma cells in vitro
1994 · External reference
Specific organ metastases of human melanoma cells injected into arterial circulation of nude nice
1991 · External reference
Evidence for a G2-checkpoint in p53-independent apoptosis induction by X-irradiation
10.1128/mcb.15.11.5849 · 1995 · External reference
Monocytic differentiation of HL-60 promyelocytic leukemia cells correlates with the induction of Bcl-xL
1997 · External reference
Camptothecin derivatives induce regression of human ovarian carcinomas grown in nude mice and distinguish between nontumorigenic and tumorigenic cells in vitro
10.1002/ijc.2910530526 · 1993 · External reference
Human melanoma: development and progression
10.1007/bf00046337 · 1990 · External reference
Regression of human breast carcinoma tumors in immunodeficient mice treated with 9-nitrocamptothecin: differential response of nontumorigenic and tumorigenic human breast cells in vitro
1993 · External reference
Establishment of human prostate tumor xenografts in nude mice and response to 9-nitrocamptothecin in vivo and in vitro does not correlate with expression of various apoptosisregulating proteins
1996 · External reference
Camptothecins: a review of their development and schedules of administration
10.1016/s0959-8049(98)00229-9 · 1998 · External reference
Mammalian G1 cyclins
10.1016/0955-0674(94)90054-x · 1994 · External reference
Several noncontiguous domains of CDK4 are involved in binding to the p16 tumor suppressor protein
10.1006/bbrc.1998.9183 · 1998 · External reference
Cooperative effects of INK4a and ras in melanoma susceptibility in vivo
10.1101/gad.11.21.2822 · 1997 · External reference
The p21 inhibitor of cyclin-dependent kinases controls DNA replication by interacting with PCNA
10.1038/369574a0 · 1994 · External reference
Growth suppression by p16INK4 requires functional retinoblastoma protein
10.1073/pnas.92.14.6289 · 1995 · External reference
Differential expression of the cyclindependent kinase inhibitors p16 and p21 in the human melanocytic system
1996 · External reference
