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References from p27KIP1 Deletions in Childhood Acute Lymphoblastic Leukemia. Local targets link to admitted publications; unresolved targets remain external evidence.
Inhibitors of mammalian G1 cyclindependent kinases
10.1101/gad.9.10.1149 · 1995 · External reference
Frequent deletion of p16INK4A, MTS1 and p15INK4B, MTS2 in pediatric acute lymphoblastic leukemia
10.1182/blood.v85.9.2321.bloodjournal8592321 · 1995 · External reference
Deletions of the cyclin dependent kinase-4 inhibitor gene in multiple human cancers
10.1038/368753a0 · 1994 · External reference
A cell cycle regulator potentially involved in genesis of many tumor types
10.1126/science.8153634 · 1994 · External reference
p27KIP1, a cyclin-CDK inhibitor, links transforming growth factor-beta and contact inhibition to cell cycle arrest
10.1101/gad.8.1.9 · 1994 · External reference
Cloning of p27KIP1, a cyclin-dependent kinase inhibitor and a potential mediator of extracellular antimitogenic signals
10.1016/0092-8674(94)90572-x · 1994 · External reference
p27, a novel inhibitor of G1 cyclin-CDK protein kinase activity, is related to p21
10.1016/0092-8674(94)90573-8 · 1994 · External reference
WAF1, a potential mediator of p53 tumor suppression
10.1016/0092-8674(93)90500-p · 1993 · External reference
The p21 CDK-interacting protein Cip1 is a potent inhibitor of G1 cyclindependent kinases
10.1016/0092-8674(93)90499-g · 1993 · External reference
p21 is a universal inhibitor of cyclin kinases
10.1038/366701a0 · 1993 · External reference
p57KIP2 a structurally distinct member of the p21CIP1 CDK inhibitor family, is a candidate tumor suppressor gene
10.1101/gad.9.6.650 · 1995 · External reference
Cloning of p57KIP2, a cyclin-dependent kinase inhibitor with unique domain structure and tissue distribution
10.1101/gad.9.6.639 · 1995 · External reference
p53 dependent inhibition of cyclin-dependent kinase activities in human fibroblasts during radiation-induced G1 arrest
10.1016/0092-8674(94)90379-4 · 1994 · External reference
Cancer cell cycles
10.1126/science.274.5293.1672 · 1996 · External reference
p27KIP1: chromosomal mapping to 12p12-12p13.1 and absence of mutations in human tumors
1995 · External reference
Assignment of the human p27KIP1 gene to 12p13 and its analysis in leukemias
1995 · External reference
Molecular analysis of the cyclin-dependent kinase inhibitor gene p27KIP1 in human malignancies
1995 · External reference
Loss of heterozygosity in the chromosomal region 12p12-13 is very common in childhood acute lymphoblastic leukemia and permits the precise localization of a tumorsuppressor gene distinct from p27KIP1
10.1182/blood.v86.10.3869.bloodjournal86103869 · 1995 · External reference
A syndrome of multiorgan hyperplasia with features of gigantism, tumorigenesis, and female sterility in p27KIP1-deficient mice
10.1016/s0092-8674(00)81239-8 · 1996 · External reference
Mice lacking p27KIP1 display increased body size, mutiple organ hyperplasia, retinal dysplasia, and pituitary tumors
10.1016/s0092-8674(00)81237-4 · 1996 · External reference
Enhanced growth of mice lacking the cyclin-dependent kinase inhibitor function of p27KIP1
10.1016/s0092-8674(00)81238-6 · 1996 · External reference
The murine gene p27KIP1 is haploinsufficient for tumour suppression
10.1038/24179 · 1998 · External reference
Genomic organization, chromosomal localization, and independent expression of human cyclin D genes
10.1016/0888-7543(92)90126-d · 1992 · External reference
Protein tyrosine phosphatase containing SH2 domains: characterization, preferential expression in hematopoietic cells, and localization to human chromosome 12p12-p13
10.1128/mcb.12.2.836 · 1992 · External reference
Localization and polymorphism of a chromosome 12-specific alpha satellite DNA sequence
10.1159/000132934 · 1990 · External reference
Construction of T-vectors, a rapid and general system for direct cloning of unmodified PCR products
10.1093/nar/19.5.1154 · 1991 · External reference
Unresolved reference
1996 · External reference
Coamplification of the CDK4 gene with MDM2 and GLI in human sarcomas
1993 · External reference
TEL-AML1 fusion resulting from a cryptic t(12;21) is the most common genetic lesion in pediatric ALL and defines a subgroup of patients with an excellent prognosis
1995 · External reference
New chromosomal translocations correlate with specific immunophenotypes of childhood acute lymphoblastic leukemia
10.1016/0092-8674(84)90078-3 · 1984 · External reference
Nonrandom involvement of the 12p12 breakpoint in chromosome abnormalities of childhood acute lymphoblastic leukemia
10.1182/blood.v68.1.69.69 · 1986 · External reference
Abnormalities of the short arm of chromosome 12 in acute nonlymphocytic leukemia and dysmyelopoietic syndrome
10.1016/0165-4608(86)90057-9 · 1986 · External reference
Alterations of the p27KIP1 gene in non-Hodgkin's lymphomas and adult T-cell leukemia/lymphoma
10.1182/blood.v86.5.1924.bloodjournal8651924 · 1995 · External reference
Frequent loss of heterozygosity at the TEL gene locus in acute lymphoblastic leukemia of childhood
10.1182/blood.v86.1.38.bloodjournal86138 · 1995 · External reference
TEL and KIP1 define the smallest region of deletions on 12p13 in hematopoietic malignancies
10.1182/blood.v86.4.1525.bloodjournal8641525 · 1995 · External reference
Mutational analysis of the candidate tumor suppressor genes TEL and KIP1 in childhood acute lymphoblastic leukemia
1996 · External reference
TEL is one of the targets for deletion on 12p in many cases of childhood B-lineage acute lymphoblastic leukemia
10.1038/sj.leu.2400743 · 1997 · External reference
Inactivation of p27KIP1 by the viral EIA oncoprotein in TGFβ-treated cells
10.1038/380262a0 · 1996 · External reference
p21-containing cyclin kinases exist in both active and inactive states
10.1101/gad.8.15.1750 · 1994 · External reference
Differential interaction of the cyclin-dependent kinase (CDK) inhibitor p27KIP1 with cyclin ACDK2 and cyclin D2-CDK4
10.1074/jbc.272.41.25863 · 1997 · External reference
New functional activities for the p21 family of CDK inhibitors
10.1101/gad.11.7.847 · 1997 · External reference
p21WAF,CIP1 mutants deficient in inhibiting cyclin-dependent kinases (CDKs) can promote assembly of active cyclin D-CDK4(6) complexes in human tumor cells
1998 · External reference
10.1093/emboj/18.6.1571
10.1093/emboj/18.6.1571 · 1999 · External reference
