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References from The Role of the Vascular Phase in Solid Tumor Growth: A Historical Review. Local targets link to admitted publications; unresolved targets remain external evidence.
The growth of malignant disease in man and the lower animals with special reference to the vascular system
10.1016/s0140-6736(01)65002-5 · 1907 · External reference
General observations on the ingrowth of new blood vessels into standardized chambers in the rabbit's ear, the subsequent changes in the newly grown vessels over a period of months
10.1002/ar.1090500203 · 1931 · External reference
Microscopic observations on the growth of blood capillaries in the living mammals
10.1002/aja.1000640203 · 1939 · External reference
Vascularization of the Brown-Pearce rabbit epithelioma transplant as seen in the transparent ear chambers
1939 · External reference
Vascular reactions of normal and malignant tissue in vivo
10.1093/jnci/6.1.73 · 1945 · External reference
The role of graft and host vessels in vascularization of grafts of normal and neoplastic tissues
1956 · External reference
Tumor angiogenesis: transfilter diffusion studied in the hamster by the transparent chamber technique
1968 · External reference
Choriocarcinoma: transfilter stimulation of vasoproliferation in the hamster cheek pouch studied by light and electron microscopy
1968 · External reference
Isolation of a tumor fraction responsible for angiogenesis
10.1084/jem.133.2.275 · 1971 · External reference
Isolation of the nonhistone proteins of rat Walker 256 carcinoma
1973 · External reference
Endothelium stimulating factor from Walker carcinoma cells
1979 · External reference
An angiogenic factor isolated from tumours: a potent low-molecular weight compound
10.1038/bjc.1979.206 · 1979 · External reference
Nucleoside requirements for the in vivo growth of bovine aortic endothelial cells
10.1002/jcp.1041080311 · 1981 · External reference
Heparin binds endothelial cell growth factor, the principal cell mitogen in bovine brain
10.1126/science.6382607 · 1984 · External reference
Heparin-affinity: purification of a tumor-derived capillary endothelial cell growth factor
10.1126/science.6199844 · 1984 · External reference
Pituitary follicular cells secrete a novel heparin-binding growth factor specific for vascular endothelial cells
10.1016/0006-291x(89)92678-8 · 1989 · External reference
Isolation and characterization of a newly identified endothelial cell mitogen produced by AtT20 cells
10.1002/j.1460-2075.1989.tb08557.x · 1989 · External reference
Angiogenesis is stimulated by a tumor-derived endothelial cell growth factor
10.1002/jcb.240290402 · 1985 · External reference
Isolation and partial molecular characterization of pituitary fibroblast growth factor
10.1073/pnas.81.17.5364 · 1984 · External reference
Isolation of brain fibroblast growth factor by heparin-sepharose affinity chromatography: identity with pituitary fibroblast growth factor
10.1073/pnas.81.22.6963 · 1984 · External reference
Primary structure of bovine pituitary basic fibroblast growth factor (FGF) and comparison with the amino-terminal sequence of bovine brain acidic FGF
10.1073/pnas.82.19.6507 · 1985 · External reference
Vascular endothelial growth factor is a secreted angiogenic mitogen
10.1126/science.2479986 · 1989 · External reference
Tumor cells secrete a vascular permeability factor that promotes accumulation of ascites fluids
10.1126/science.6823562 · 1983 · External reference
Vascular permeability factor, an endothelial cell mitogen related to platelet derived growth factor
10.1126/science.2479987 · 1989 · External reference
Amino acid and cDNA sequences of a vascular endothelial cell mitogen that is homologous to platelet-derived growth factor
10.1073/pnas.87.7.2628 · 1990 · External reference
Isolation and characterization of a vascular endothelial cell mitogen produced by pituitary-derived foil iculostellate cells
10.1073/pnas.86.19.7311 · 1989 · External reference
Tumor vascular permeability factor stimulates endothelial cell growth and angiogenesis
10.1172/jci114322 · 1989 · External reference
An endothelial cell growth factor from the mouse neuroblastoma cell line NB41
10.3109/08977198909069077 · 1989 · External reference
Vascular permeability factor, tumor angiogenesis and stroma generation
1995 · External reference
Potent synergism between vascular endothelial growth factor and basic fibroblast growth factor in the induction of angiogenesis in vitro
10.1016/0006-291x(92)92277-5 · 1992 · External reference
Synergistic effects of vascular endothelial growth factor and basic fibroblast growth factor on bovine capillary endothelial cells within collagen gels
1993 · External reference
Synergistic effect of vascular endothelial growth factor and basic fibroblast growth factor on angiogenesis in vivo
10.1161/01.cir.92.9.365 · 1995 · External reference
Angiogenesis: a marker for neoplastic transformation of mammary papillary hyperplasia
10.1126/science.402692 · 1977 · External reference
Angiogenesis as a marker of preneoplastic lesions of the human breast
10.1002/1097-0142(197801)41:1<239::aid-cncr2820410133>3.0.co;2-x · 1978 · External reference
Acquisition of angiogenic capacity and neoplastic transformation in the rat mammary gland
1978 · External reference
Self-regulation of growth in threedimension
10.1084/jem.138.4.745 · 1973 · External reference
Tumor dormancy in vivo by prevention of neovascularization
10.1084/jem.136.2.261 · 1972 · External reference
Growth and metastasis of tumor in organ culture
10.1002/1097-0142(196304)16:4<453::aid-cncr2820160407>3.0.co;2-y · 1963 · External reference
Tumor angiogenesis: rapid induction of endothelial mitosis demonstrated by autoradiography
10.1083/jcb.54.2.408 · 1972 · External reference
Ultrastructural autoradiographic studies of the early vasoproliferative response in tumor angiogenesis
1973 · External reference
Tumor growth and neovascularization: an experimental model using the rabbit cornea
10.1093/jnci/52.2.413 · 1974 · External reference
Induction of angiogenesis during the transition from hyperplasia to neoplasia
10.1038/339058a0 · 1989 · External reference
Interactions between newly formed endothelial channels and carcinoma cells in plasma clot culture
10.1007/bf00119076 · 1986 · External reference
Heritable formation of pancreatic beta-cell tumors in transgenic mice expressing recombinant insulin/simian virus 40 oncogene
10.1038/315115a0 · 1985 · External reference
Neovascularization is associated with a switch to the export of bFGF
10.1016/0092-8674(91)90033-u · 1991 · External reference
Extracellular matrix-resident growth factors and enzymes: possible involvement in tumor metastasis and angiogenesis
10.1007/bf00046361 · 1990 · External reference
Macrophage-induced angiogenesis is mediated by tumor necrosis factor-α
10.1038/329630a0 · 1987 · External reference
Regulation of the activity of a new inhibitor of angiogenesis by a cancer suppressor gene
10.1016/0092-8674(89)90238-9 · 1989 · External reference
A tumor suppressor-dependent inhibitor of angiogenesis is immunologically and functionally indis tinguishable from a fragment of thrombospondin
10.1073/pnas.87.17.6624 · 1990 · External reference
Control of angiogenesis in fibroblasts by p53 regulation of thrombospondin-1
10.1126/science.7521539 · 1994 · External reference
Thrombospondins: structure and regulation of expression
10.1096/fasebj.6.14.1426766 · 1992 · External reference
Suppression of solid tumor growth by immunoneutralizing monoclonal antibody against human basic fibroblast growth factor
1991 · External reference
Inhibition of vascular endothelial growth factor-induced growth in vivo
10.1038/362841a0 · 1993 · External reference
Glioblastoma growth inhibited in vivo by a dominant-negative Flk-1 mutant
10.1038/367576a0 · 1994 · External reference
Quantitative relationships of intravascular tumor cells, tumor vessels, pulmonary metastases following tumor implantation
1974 · External reference
Vascular permeability factor/vascular endothelial growth factor, microvascular hyperpermeability, angiogenesis
1995 · External reference
Quantitation of cell shedding into efferent blood of mammary adenocarcinoma
1975 · External reference
Angiogenesis and tumor metastasis
10.1146/annurev.med.49.1.407 · 1998 · External reference
A new class of steroids inhibits angiogenesis in the presence of heparin or a heparin fragment
10.1126/science.2416056 · 1985 · External reference
Thalidomide is an inhibitor of angiogenesis
10.1073/pnas.91.9.4082 · 1994 · External reference
Angioinhibins: synthetic analogues of fumagillin which inhibit angiogenesis and suppress tumor growth
10.1038/348555a0 · 1990 · External reference
Comparison of the inhibitory effect of the angiogenesis inhibitor, TNP-470, mitomycin C on the growth and liver metastasis of human colon cancer
10.1002/ijc.2910610221 · 1995 · External reference
Suppression of pulmonary metastasis by angiogenesis inhibitor TNP-470 in murine osteosarcoma
10.1002/ijc.2910610125 · 1995 · External reference
Transfection of thrombospondin 1 complementary DNA into a human breast carcinoma cell line reduces primary tumor growth, metastatic potential, angiogenesis
1994 · External reference
Angiostatin: a novel angiogenesis inhibitor that mediates the suppression of metastases by a Lewis lung carcinoma
10.1016/0092-8674(94)90200-3 · 1994 · External reference
Endostatin: an endogenous inhibitor of angiogenesis and tumor growth
10.1016/s0092-8674(00)81848-6 · 1997 · External reference
Inhibition of development of murine melanoma lung metastases by systemic administration of recombinant platelet factor 4
10.1093/jnci/87.4.304 · 1995 · External reference
Dormancy of micrometastases: balanced proliferation and apoptosis in the presence of angiogenesis suppression
10.1038/nm0295-149 · 1995 · External reference
Tumor angiogenesis: a quantitative method for histologic grading
1972 · External reference
Tumor angiogenesis and metastasis
1991 · External reference
Clinical importance of the determination of tumor angiogenesis in breast carcinoma: much more than a new prognostic tool: review
10.1200/jco.1995.13.3.765 · 1995 · External reference
The prognostic significance of tumor vascularity in intermediate thickness (0.76–4 mm thick) skin melanoma: a quantitative histologic study
1988 · External reference
Tumor angiogenesis correlates with metastasis in invasive prostate carcinoma
1993 · External reference
Quantitative microvessel density, a staging and prognostic marker for human prostatic carcinoma
10.1002/(sici)1097-0142(19960715)78:2<345::aid-cncr25>3.0.co;2-v · 1996 · External reference
Tumor angiogenesis in human lung adenocarcinoma
10.1002/1097-0142(19941015)74:8<2245::aid-cncr2820740807>3.0.co;2-x · 1994 · External reference
Prognostic significance of tumoral angiogenesis in completely resected late stage lung carcinoma (stage IIIA-N2): impact of adjuvant therapies in a subset of patients at high risk of recurrence
10.1002/(sici)1097-0142(19960801)78:3<409::aid-cncr5>3.0.co;2-e · 1996 · External reference
Tumor angiogenesis is a predictor of recurrence in gastric carcinoma
10.1200/jco.1995.13.2.477 · 1995 · External reference
Tumor angiogenesis as a prognostic factor in cervical carcinoma
10.1006/gyno.1995.1062 · 1995 · External reference
Tumor angiogenesis in advanced stage ovarian carcinoma
1995 · External reference
Intratumoral microvessel density and p53 protein: correlation with metastasis in head and neck squamous-cell carcinoma
10.1002/ijc.2910550507 · 1993 · External reference
Bone marrow angiogenesis and progression in multiple myeloma
10.1111/j.1365-2141.1994.tb08304.x · 1994 · External reference
Bone marrow neovascularization, plasma cell angiogenic potential and matrix metalloproteinase 2 secretion parallel progression of human multiple myeloma
10.1182/blood.v93.9.3064 · 1999 · External reference
Bone marrow angiogenesis and mast cell density increase simultaneously with progression of human multiple myeloma
10.1038/sj.bjc.6690070 · 1999 · External reference
Angiogenesis spectrum in the stroma of B-cell non-Hodgkin's lymphomas
10.1111/j.1600-0609.1996.tb00293.x · 1996 · External reference
Do mast cells help angiogenesis in B-cell non-Hodgkin's lymphomas?
10.1038/bjc.1998.316 · 1998 · External reference
Angiogenesis extent and macrophage density increase simultaneously with pathological pro gression in B-cell non-Hodgkin's lymphomas
10.1038/sj.bjc.6690154 · 1999 · External reference
Microvessel count and cerebrospinal fluid basic fibroblast growth factor in children with brain tumours
10.1016/s0140-6736(94)91280-7 · 1994 · External reference
Serum basic fibroblast growth factor in men with and without prostate cancer
10.1002/1097-0142(19951201)76:11<2304::aid-cncr2820761119>3.0.co;2-n · 1995 · External reference
Elevated levels of an angiogenic peptide, basic fibroblast growth factor, in the urine of patients with a wide spectrum of cancers
10.1093/jnci/86.5.356 · 1994 · External reference
Transcriptional regulation of the rat vascular endothelial growth factor gene by hypoxia
10.1074/jbc.270.22.13333 · 1995 · External reference
Vascular endothelial growth factor is a potent tumor angiogenesis factor in human gliomas in vivo
10.1038/359845a0 · 1992 · External reference
Vascular endothelial growth factor induced by hypoxia may mediate hypoxia-initiated angiogenesis
10.1038/359843a0 · 1992 · External reference
Mammary fibroblasts may influence breast tumor angiogenesis via hypoxiainduced vascular endothelial growth factor upregulation and protein expression
1994 · External reference
Vascular permeability factor expression influences tumor angiogenesis in human melanoma lines xenografted to nude mice
1995 · External reference
Expression of vascular permeability factor/vascular endothelial growth factor by melanoma cells increases tumor growth, angiogenesis, experimental metastasis
1996 · External reference
Upregulation of vascular endothelial growth factor expression in a rat glioma is conferred by two distinct hypoxia-driven mechanisms
1997 · External reference
Transcriptional regulation by hypoxia-inducible factor-1
10.1016/1050-1738(96)00039-4 · 1996 · External reference
Role of HIF-1 in hypoxia-mediated apoptosis, cell proliferation and tumor angiogenesis
10.1038/28867 · 1998 · External reference
Angiogenesis and inflammation
1992 · External reference
Chemokines
10.1182/blood.v90.3.909 · 1997 · External reference
Regulation of hostmediated anti-tumor mechanism of cytokines
1997 · External reference
Macrophages and angiogenesis
10.1002/jlb.55.3.410 · 1994 · External reference
The role of macrophages in tumour angiogenesis
1997 · External reference
Mast cell and tumor angiogenesis
10.1002/ijc.2910180520 · 1976 · External reference
Mst cell-deficient W/Wv mice exhibit a decreased rate of tumor angiogenesis
10.1002/ijc.2910420110 · 1988 · External reference
Role of mast cells in mitogenesis and angiogenesis in normal tissues and tumor tissues
1993 · External reference
Mast cell are a major source of basic fibroblast growth factor in chronic inflammation and cutaneous hemangiomas
1995 · External reference
Angiogenic factors stimulate mast cell migration
10.1182/blood.v86.7.2488.2488 · 1995 · External reference
Detection of intracellular interleukin-8 in human mast cells: flow cytometry as a guide for immunoelectron microscopy
10.1177/002215549704500703 · 1997 · External reference
Synthesis, storage and release of vascular endothelial growth factor/vascular permeability factor (VEGF/VPF) by human mast cells: implications for the biological significance of VEGF 206
10.1091/mbc.9.4.875 · 1998 · External reference
Comparative cytokine gene expression: regulation and release by human mast cells
10.1046/j.1365-2567.1998.00425.x · 1998 · External reference
T lymphocytes synthesize and export heparin-binding epidermal growth factor-like growth factor and basic fibroblast growth factor, mitogens for vascular cells and fibroblasts: differential production and release by CD4+ and CD8+ cells
10.1073/pnas.91.8.2890 · 1995 · External reference
Peripheral blood T lymphocytes and lymphocytes infiltrating human cancer express vascular endothelial growth factor: a potential role for T cells in angiogenesis
1995 · External reference
Isolation of angiopoietin-1, a ligand for the TIE2 receptor, by secretion-trap expression cloning
10.1016/s0092-8674(00)81812-7 · 1996 · External reference
Angiopoietin 2, a natural antagonist for Tie-2 that disrupts in vivo angiogenesis
10.1126/science.277.5322.55 · 1997 · External reference
tek, a novel tyrosine kinase gene located on mouse chromosome 4, is expressed in endothelial cells, their presumptive precursors
1992 · External reference
A novel endothelial cell surface receptor tyrosine kinase with extracellular epidermal growth factor homology domains
10.1128/mcb.12.4.1698 · 1992 · External reference
Tie-1 and Tie-2 define another class of putative receptor tyrosine kinase genes expressed in early embryonic vascular system
10.1073/pnas.90.20.9355 · 1993 · External reference
Vascular development: cellular and molecular regulation
10.1096/fasebj.11.5.9141503 · 1997 · External reference
Distinct roles of the receptor tyrosine kinase Tie-1 and Tie-2 in blood vessel formation
10.1038/376070a0 · 1995 · External reference
Requisite role of angiopoietin1, a ligand for the TIE2 receptor, during embryonic angiogenesis
10.1016/s0092-8674(00)81813-9 · 1996 · External reference
Vessel cooption, regression and growth in tumors mediated by angiopoietins and VEGF
10.1126/science.284.5422.1994 · 1999 · External reference
Cell-type specific expression of angiopoietin-1 and angiopoietin-2 suggests a role in glioblastoma angiogenesis
10.1016/s0002-9440(10)65733-1 · 1998 · External reference
Biologic significance of angiopoietin-2 expression in human hepatocellular carcinoma
10.1172/jci4891 · 1999 · External reference
Inhibition of capillary endothelial cell growth by pericytes and smooth muscle cells
10.1083/jcb.105.3.1455 · 1987 · External reference
An activated form of transforming growth factor-β is produced by cocultures of endothelial cells and pericytes
10.1073/pnas.86.12.4544 · 1989 · External reference
Pericyte loss microaneurysm formation in PDGF-B deficient mice
10.1126/science.277.5323.242 · 1997 · External reference
Signaling vascular morphogenesis and maintenance
10.1126/science.277.5322.48 · 1997 · External reference
Vascular endothelial growth factor acts as a pericyte mitogen under hypoxic conditions
1999 · External reference
Capillary growth in mesentery of normal young rats
1989 · External reference
Mice deficient for PDGF-B show renal, cardiovascular and hematological abnormalities
10.1101/gad.8.16.1875 · 1994 · External reference
Early and extensive contribution of pericytes/vascular smooth muscle cells to microvascular proliferation in glioblastoma multiforme: an immunolight and immunoelectron microscopic study
10.1097/00005072-199505000-00003 · 1995 · External reference
Immunohistochemical localization of transforming growth factor-beta 1 in Kaposi's sarcoma
10.1016/0046-8177(95)90241-4 · 1995 · External reference
Tumor angiogenesis: therapeutic implications
10.1056/nejm197111182852108 · 1971 · External reference
The resistance of certain tissues to invasion: penetrability of explanted tissues by vascularized mesenchyme
1973 · External reference
TNP-470 (AGM-1470): mechanisms of action and early clinical development
10.1016/s0959-8049(96)00388-7 · 1996 · External reference
Angiogenesis and angiogenesis inhibitors in paediatric diseases
10.1007/bf01957746 · 1991 · External reference
Experimental and clinical studies on the use of matrix metalloproteinase inhibitors for the treatment of cancer
1996 · External reference
Requirement of vascular integrin αvβ3 for angiogenesis
10.1126/science.7512751 · 1994 · External reference
Definitions of two angiogenic pathways by distinct integrins
10.1126/science.270.5241.1500 · 1995 · External reference
Anti-angiogenic drugs as a novel anticancer therapeutic strategy
1997 · External reference
Angiostatin induces and sustains dormancy of human primary tumors in mice
10.1038/nm0696-689 · 1996 · External reference
Relation of neovascularization to metastasis of non-small celllung cancer
10.1016/0140-6736(92)93217-b · 1992 · External reference