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References from The “Comparative Growth Assay”: Examining the Interplay of Anti-cancer Agents with Cells Carrying Single Gene Alterations. Local targets link to admitted publications; unresolved targets remain external evidence.
Ex vivo cytotoxic drug evaluation by DiSC assay to expedite identification of clinical targets: results with 8-chloro-cAMP
10.1038/bjc.1997.417 · 1997 · External reference
An information-intensive approach to the molecular pharmacology of cancer
10.1126/science.275.5298.343 · 1997 · External reference
Green fluorescent protein as a marker for gene expression
10.1126/science.8303295 · 1994 · External reference
Using GFP to see the light
10.1016/s0168-9525(00)89090-3 · 1995 · External reference
In vitro and in vivo resistance to cisplatin in cells that have lost DNA mismatch repair
1997 · External reference
The effect of different chemotherapeutic agents on the enrichment of DNA mismatch repair-deficient tumour cells
10.1038/bjc.1998.116 · 1998 · External reference
Human chromosome 3 corrects mismatch repair deficiency and microsatellite instability and reduces N-methyl-N-nitro-N-nitrosoguanidine tolerance in colon tumor cells with homozygous hMLH1 mutation
1994 · External reference
A multidrug resistance transporter from human MCF-7 breast cancer cells
10.1073/pnas.95.26.15665 · 1998 · External reference
Mechanisms and biological effects of mismatch repair
10.1146/annurev.ge.25.120191.001305 · 1991 · External reference
Mismatch repair, genetic stability and tumour avoidance
10.1098/rstb.1995.0014 · 1995 · External reference
Identification of mismatch repair genes and their role in the development of cancer
10.1016/0959-437x(95)80055-7 · 1995 · External reference
Ubiquitous somatic mutations in simple repeated sequences reveal a new mechanism for colonic carcinogenesis
10.1038/363558a0 · 1993 · External reference
Mismatch repair gene defects in sporadic colorectal cancers with microsatellite instability
10.1038/ng0195-48 · 1995 · External reference
hMLH1 expression and cellular responses of ovarian tumour cells to treatment with cytotoxic anticancer agents
10.1038/sj.onc.1201167 · 1997 · External reference
A naturally occurring hPMS2 mutation can confer a dominant negative mutator phenotype
10.1128/mcb.18.3.1635 · 1998 · External reference
An alkylation-tolerant, mutator human cell line is deficient in strand-specific mismatch repair
10.1073/pnas.90.14.6424 · 1993 · External reference
Loss of DNA mismatch repair in acquired resistance to cisplatin
1996 · External reference
Cisplatin and adriamycin resistance are associated with MutLalpha and mismatch repair deficiency in an ovarian tumor cell line
10.1074/jbc.271.33.19645 · 1996 · External reference
The role of DNA mismatch repair in platinum drug resistance
1996 · External reference
Role of postreplicative DNA mismatch repair in the cytotoxic action of thioguanine
10.1126/science.273.5278.1109 · 1996 · External reference
The mismatch-repair protein hMSH2 binds selectively to DNA adducts of the anticancer drug cisplatin
10.1016/s1074-5521(96)90149-0 · 1996 · External reference
Microsatellite instability, apoptosis, loss of p53 function in drug-resistant tumor cells
1996 · External reference
Atypical multidrug resistance: breast cancer resistance protein messenger RNA expression in mitoxantrone-selected cell lines
10.1093/jnci/91.5.429 · 1999 · External reference
DNA-dependent protein kinase inhibitor (OK-1035) suppresses p21 expression in HCT116 cells containing wild-type p53 induced by adriamycin
10.1006/bbrc.1996.0575 · 1996 · External reference
Inhibition of human tumor xenograft growth by treatment with the farnesyl transferase inhibitor B956
1995 · External reference
Microsatellite instability and mutations of the transforming growth factor beta type II receptor gene in colorectal cancer
1995 · External reference
Modulation of differentiation-related responses in human colon carcinoma cells by protein kinase inhibitor H-7
1992 · External reference
Growth control in a human colon carcinoma cell line mediated by cell- associated transforming growth factor-alpha (TGF alpha)
10.1006/excr.1993.1119 · 1993 · External reference
Autocrine transforming growth factor-beta 1 and beta 2 expression is increased by cell crowding and quiescence in colon carcinoma cells
10.1006/excr.1994.1251 · 1994 · External reference
An enhanced green fluorescent protein allows sensitive detection of gene transfer in mammalian cells
10.1006/bbrc.1996.1573 · 1996 · External reference
Competency in mismatch repair prohibits clonal expansion of cancer cells treated with N-methyl-N-nitro-N-nitrosoguanidine
10.1172/jci118767 · 1996 · External reference
Frequent microsatellite instability in primary small cell lung cancer
1994 · External reference
Clinical and pathological characteristics of sporadic colorectal carcinomas with DNA replication errors in microsatellite sequences
1994 · External reference
Microsatellite instability in oral cancer
10.1002/ijc.2910640509 · 1995 · External reference
Microsatellite instability in human testicular germ cell tumours
10.1038/bjc.1995.387 · 1995 · External reference
Genetic instability occurs in the majority of young patients with colorectal cancer
10.1038/nm0495-348 · 1995 · External reference
Microsatellite instability and other molecular abnormalities in human prostate cancer
10.1111/j.1349-7006.1995.tb03007.x · 1995 · External reference
Mutations in MLH1 are more frequent than in MSH2 in sporadic colorectal cancers with microsatellite instability
10.1002/(sici)1098-2264(199701)18:1<42::aid-gcc5>3.0.co;2-1 · 1997 · External reference
Methylation of the hMLH1 promoter correlates with lack of expression of hMLH1 in sporadic colon tumors and mismatch repair-defective human tumor cell lines
1997 · External reference
Repeat expansion detection analysis of (CAG)n tracts in tumor cell lines, testicular tumors, testicular cancer families
1997 · External reference
Microsatellite instability is associated with tumors that characterize the hereditary non-polyposis colorectal carcinoma syndrome
1993 · External reference
Mismatch repair genes matched to several new roles in cancer
10.1093/jnci/88.14.950 · 1996 · External reference
Defective expression of the DNA mismatch repair protein, MLH1, alters G2-M cell cycle checkpoint arrest following ionizing radiation
1998 · External reference
Methylator resistance mediated by mismatch repair deficiency in a glioblastoma multiforme xenograft
1997 · External reference
Characterisation of the unusual expression of cross-resistance to cisplatin in a series of etoposide-selected resistant sublines of the SuSa testicular teratoma cell line
10.1016/0006-2952(94)90476-6 · 1994 · External reference
Cross-resistance to diverse drugs is associated with primary cisplatin resistance in ovarian cancer cell lines
1993 · External reference
Role of DNA mismatch repair in the cytotoxicity of ionizing radiation
1997 · External reference
Hypermutability and mismatch repair deficiency in RER+ tumor cells
10.1016/0092-8674(93)90331-j · 1993 · External reference
Ovarian cancer, from the laboratory to the clinic: challenges for the future
10.1093/oxfordjournals.annonc.a010488 · 1996 · External reference
Reduced expression of mismatch repair genes measured by multiplex reverse transcription-polymerase chain reaction inhuman gliomas
1997 · External reference
