Research graph
References from BRCA1 Partially Reverses the Transforming Activity of the ras Oncogene. Local targets link to admitted publications; unresolved targets remain external evidence.
Inherited breast and ovarian cancers
10.1093/hmg/4.suppl_1.1811 · 1995 · External reference
A strong candidate for the breast and ovarian cancer susceptibility gene BRCA1
10.1126/science.7545954 · 1994 · External reference
Localization of a breast cancer susceptibility gene, BRCA2, to chromosome 13q12–13
10.1126/science.8091231 · 1994 · External reference
BRCA1 sequence analysis in women at high risk for susceptibility mutations
10.1001/jama.1997.03550150046034 · 1997 · External reference
BRCA1 a review of structure and putative functions
10.1155/1998/298530 · 1998 · External reference
Transcriptional activation by BRCA1
10.1038/382678a0 · 1996 · External reference
Association of BRCA1 with Rad51 in mitotic and meiotic cells
10.1016/s0092-8674(00)81847-4 · 1997 · External reference
Arrest of the cell cycle by the tumor-suppressor BRCA1 requires the CDK-inhibitor p21WAF1/Cip1
10.1038/38291 · 1997 · External reference
The tumor suppressor gene BRCA1 is required for embryonic cellular proliferation in the mouse
10.1016/s0092-8674(00)81302-1 · 1996 · External reference
Allele loss in the region 17q12-21 in familial breast and ovarian cancer involve the wild-type chromosome
10.1038/ng1092-128 · 1992 · External reference
Differential subcellular localization, expression and biological toxicity of BRCA1 and the spice variant BRCA1-Δ11b
10.1038/sj.onc.1200924 · 1997 · External reference
Induction to apoptosis by the tumor-suppressor protein BRCA1
1996 · External reference
Decreased expression of BRCA1 accelerates growth and is often present during sporadic breast cancer progression
10.1038/ng0495-444 · 1995 · External reference
Antisense RNA to the putative tumor-suppressor gene BRCA1 transformsmouse fibroblasts
1996 · External reference
Growth retardation and tumor inhibition by BRCA1
10.1038/ng0396-298 · 1996 · External reference
Increasing complexity of the ras signalling pathway
10.1074/jbc.273.32.19925 · 1998 · External reference
Ras oncogenes in human cancer: a review
1989 · External reference
Advanced mammalian gene transfer: high titre retroviral vectors with multiple drug selection markers and a complementary helper-free packaging cell line
10.1093/nar/18.12.3587 · 1990 · External reference
Transformation of primary rat embryo cells
10.1016/0076-6879(95)54005-9 · 1995 · External reference
Detection and localization of BRCA1 in cell lines with monoclonal antibodies
1998 · External reference
Therapy of streptozotocin induced diabetes with a bifunctional antibody that delivers vinca alkaloids to IL-2 receptor positive cells
10.3109/08916939508995314 · 1995 · External reference
BRCAI regulates p53-dependent gene expression
10.1073/pnas.95.5.2302 · 1998 · External reference
Transforming collaborations between ras and nuclear oncogenes
1990 · External reference
Partial rescue of BRCAI early embryonic lethality by p53 or p21WAF1/Cip1 null mutations
10.1038/ng0797-298 · 1997 · External reference
BRCA1 binds c-myc and inhibits its transcriptional and transforming activity in cells
10.1038/sj.onc.1202403 · 1998 · External reference
Breast cancer genes: therapeutic strategies
10.1111/j.1749-6632.1997.tb48590.x · 1997 · External reference
Ovarian cancer gene therapy
10.1016/s0889-8588(05)70007-1 · 1998 · External reference
Clinical phase 1 gene therapy trial using BRCA1 retrovirus is safe
1998 · External reference