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References from Killing of Brain Tumor Cells by Hypoxia-Responsive Element Mediated Expression of BAX. Local targets link to admitted publications; unresolved targets remain external evidence.
Evaluation of BCNU and/or radiotherapy in the treatment of anaplastic gliomas
10.3171/jns.1978.49.3.0333 · 1978 · External reference
An analysis of dose-effect relationship in the radiotherapy of malignant gliomas
10.1016/0360-3016(79)90553-4 · 1979 · External reference
Intratumoral oxygen pressure in malignant brain tumor
10.3171/jns.1991.74.1.0055 · 1991 · External reference
Direct measurement of PO2 distribution and bioreductive enzymes in human malignant brain tumors
10.1016/0360-3016(94)90432-4 · 1994 · External reference
Blood flow, oxygen and nutrient supply, and metabolic microenvironment of human tumors: a review
1989 · External reference
Evidence for acutely hypoxic cells in mouse tumors and a possible mechanism for reoxygenation
10.1259/0007-1285-52-620-650 · 1979 · External reference
Acute hypoxia in tumors: implications for modifiers of radiation effects
10.1016/0360-3016(86)90153-7 · 1986 · External reference
Unresolved reference
1993 · External reference
Cells at intermediate oxygen levels can be more important than the “hypoxic fraction” in determining tumor response to fractionated radiotherapy
10.2307/3579620 · 1997 · External reference
Hypoxia-inducible factor 1 and the molecular physiology of oxygen homeostasis
10.1016/s0022-2143(98)90091-9 · 1998 · External reference
Oxygen sensing: hypoxia-inducible factor-1 and the regulation of mammalian gene expression
10.1242/jeb.201.8.1153 · 1998 · External reference
Hypoxiainducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension
10.1073/pnas.92.12.5510 · 1995 · External reference
Hypoxia-inducible factor 1 levels vary exponentially over a physiologically relevant range of O2 tension
10.1152/ajpcell.1996.271.4.c1172 · 1996 · External reference
Cellular and developmental control of O2 homeostasis by hypoxia-inducible factor Iα
10.1101/gad.12.2.149 · 1998 · External reference
HIF-1α in hypoxia-mediated apoptosis, cell proliferation and tumor angiogenesis
10.1038/28867 · 1998 · External reference
HIF-1α is required for solid tumor formation and embryonic vascularization
10.1093/emboj/17.11.3005 · 1998 · External reference
Cloning of a factor required for activity of the Ah (dioxin) receptor
10.1126/science.1852076 · 1991 · External reference
A novel bHLH-PAS factor with close sequence similarity to hypoxia-inducible factor is regulates the VEGF expression and is potentially involved in lung and vascular development
10.1073/pnas.94.9.4273 · 1997 · External reference
Endothelial PAS domain protein 1 (EPAS 1), a transcription factor selectively expressed in endothelial cells
10.1101/gad.11.1.72 · 1997 · External reference
DNA binding specificities and pairing rules of the Ah receptor, ARNT, and SIM proteins
10.1074/jbc.270.44.26292 · 1995 · External reference
Erythropoietin: a model system for studying oxygen-dependent gene regulation
10.1242/jeb.201.8.1197 · 1998 · External reference
A nuclear factor induced by hypoxia via de novo protein synthesis binds to the human erythropoietin gene enhancer at a site required for transcriptional activation
10.1128/mcb.12.12.5447 · 1992 · External reference
Increase in BAX expression in substantia nigra following 1-methyl-4phenyl-1,2,3,6-tetrahydropyridine (MPTP) treatment of mice
10.1016/0304-3940(96)12323-5 · 1996 · External reference
The overexpression of BAX produces cell death upon induction of the mitochondrial permeability transition
10.1074/jbc.273.13.7770 · 1998 · External reference
BAX suppresses tumorigenesis and stimulates apoptosis in vivo
10.1038/385637a0 · 1997 · External reference
The Bcl-2 protein family: arbitors of cell survival
10.1126/science.281.5381.1322 · 1998 · External reference
Mitochondria and apoptosis
10.1126/science.281.5381.1309 · 1998 · External reference
Hypoxia-inducible nuclear factors bind to an enhancer element located 3' to the human erythropoietin gene
10.1073/pnas.88.13.5680 · 1991 · External reference
The histological structure of some human lung cancers and the possible implications for radiotherapy
10.1038/bjc.1955.55 · 1955 · External reference
Assessing the bioreductive effectiveness of the nitroimidazole RSU1069 and its prodrug RB6145: with particular reference to in vivo methods of evaluation
10.1007/bf00689809 · 1993 · External reference
The unique physiology of solid tumors: opportunities (and problems) for cancer therapy
1998 · External reference
Targeting gene expression to hypoxic tumor cells
10.1038/nm0597-515 · 1997 · External reference
Tumorspecific gene therapy using hypoxia-responsive gene expression
1999 · External reference
Activation of vascular endothelial growth factor gene transcription by hypoxia-inducible factor 1
10.1128/mcb.16.9.4604 · 1996 · External reference
Oxygen regulated elements in the phosphoglycerate kinase-1 and lactate dehydrogenase A genes: Similarities with the erythropoietin 3′ enhancer
10.1073/pnas.91.14.6496 · 1994 · External reference
The role of the bystander effect in suicide gene therapy
10.1016/s0959-8049(96)00483-2 · 1997 · External reference
Prodrug-activated gene therapy: involvement of an immunological component in the bystander effect
1996 · External reference