Research graph
References from Mapping of the Gene for the Human Telomerase Reverse Transcriptase, hTERT, to Chromosome 5p15.33 by Fluorescence in Situ Hybridization. Local targets link to admitted publications; unresolved targets remain external evidence.
Role of telomerase in cellular proliferation and cancer
10.1002/(sici)1097-4652(199907)180:1<10::aid-jcp2>3.0.co;2-d · 1999 · External reference
Telomerase activity in human germline and embryonic tissues and cells
10.1002/(sici)1520-6408(1996)18:2<173::aid-dvg10>3.0.co;2-3 · 1996 · External reference
Expression of the RNA component of telomerase during human development and differentiation
1998 · External reference
Specific association of human telomerase activity with immortal cells and cancer
10.1126/science.7605428 · 1994 · External reference
Telomerase activity in the regenerative basal layer of the epidermis in human skin and in immortal and carcinoma-derived skin keratinocytes
10.1073/pnas.93.13.6476 · 1996 · External reference
Telomerase activity in normal human epithelial cells
1996 · External reference
Telomerase activity concentrates in the mitotically active segments of human hair follicles
10.1111/1523-1747.ep12285654 · 1997 · External reference
A survey of telomerase activity in human cancer
10.1016/s0959-8049(97)00062-2 · 1997 · External reference
The RNA component of human telomerase
10.1126/science.7544491 · 1995 · External reference
hEST2, the putative human telomerase catalytic subunit gene, is up-regulated in tumor cells and during immortalization
10.1016/s0092-8674(00)80538-3 · 1997 · External reference
Telomerase catalytic subunit homologs from fission yeast and human
10.1126/science.277.5328.955 · 1997 · External reference
Reconstitution of human telomerase with the template RNA component and the catalytic protein subunit hTRT
10.1038/ng1297-498 · 1997 · External reference
Functional requirement of p23 and Hsp90 in telomerase complexes
10.1101/gad.13.7.817 · 1999 · External reference
DNA copy number amplifications in human neoplasms
1998 · External reference
Construction of bacterial artificial chromosome libraries using the modified P1 (PAC) system
1996 · External reference
The human telomerase catalytic subunit hTERT organization of the gene and characterization of the promoter
10.1093/hmg/8.1.137 · 1999 · External reference
Mapping of the gene for the mouse telomerase RNA component, Terc, to chromosome 3 by fluorescence in situ hybridization and mouse chromosome painting
10.1006/geno.1997.4621 · 1997 · External reference
Variation in topoisomerase I gene copy number as a mechanism for intrinsic drug sensitivity
10.1038/bjc.1996.394 · 1996 · External reference
Position effect at S
1990 · External reference
Time, telomeres and tumours: is cellular senescence more than an anticancer mechanism?
10.1016/s0962-8924(00)89044-3 · 1995 · External reference
Advanced-stage cervical carcinomas are defined by a recurrent pattern of chromosomal aberrations revealing high genetic instability and a consistent gain of chromosome arm 3q
10.1002/(sici)1098-2264(199708)19:4<233::aid-gcc5>3.0.co;2-y · 1997 · External reference
DNA gains in 3q occur frequently in squamous cell carcinoma of the lung but not in adenocarcinoma
10.1002/(sici)1098-2264(199805)22:1<79::aid-gcc11>3.0.co;2-d · 1998 · External reference
Distinct patterns of chromosomal alterations in high- and low-grade head and neck squamous cell carcinoma
1996 · External reference
Gain of DNA copy number on chromosomes 3826-gter and 5p14-pter is a frequent finding in head and neck squamous cell carcinomas
1998 · External reference
10.1016/s1368-8375(97)00079-1 · 1998 · Admitted local publication
Molecular cytogenetic fingerprinting of eosopha geal squamous cell carcinoma by comparative genomic hybridization reveals a consistent pattern of chromosomal alterations
10.1002/(sici)1098-2264(199906)25:2<160::aid-gcc12>3.0.co;2-u · 1999 · External reference
Comparative genomic hybridization of malignant fibrous histiocytoma reveals a novel prognostic marker
1997 · External reference
Loss of chromosome 13 is the most frequent genomic imbalance in malignant fibrous histiocytomas
10.1016/s0165-4608(98)00227-1 · 1999 · External reference
Analysis of chromosomal imbalances in sporadic and NF1 -associated peripheral nerve sheath tumors by comparative genomic hybridization
10.1002/(sici)1098-2264(199908)25:4<362::aid-gcc8>3.0.co;2-q · 1999 · External reference
Amplification, increased dosage and in situ expression of the telomerase RNA gene in human cancer
10.1038/sj.onc.1201066 · 1997 · External reference
Both transcriptional and posttranscriptional mechanisms regulate human telomerase template RNA levels
10.1128/mcb.19.6.3989 · 1999 · External reference
Tumour specific regulation of telomerase RNA gene expression visualized by in situ hybridization
10.1038/sj.onc.1201620 · 1998 · External reference
Comparative genomic hybridization detects novel deletions and amplifications in head and neck squamous cell carcinomas
1995 · External reference
Genomic alterations associated with malignancy in head and neck cancer
10.1002/(sici)1097-0347(199803)20:2<145::aid-hed8>3.0.co;2-2 · 1998 · External reference
DNA amplification on chromosome 3826.1-826.3 in squamous cell carcinoma of the lung detected by reverse chromosome painting
10.1016/0959-8049(96)00016-0 · 1996 · External reference
Amplification of the genes BCHE and SLC2A2 in 40% of squamous cell carcinoma of the lung
1997 · External reference
Patterns of chromosomal imbalances in adenocarcinoma and squamous cell carcinoma of the lung
1997 · External reference
Small-cell lung cancer is characterized by a high incidence of deletions on chromosomes 3p, 4q, 5q, 10q, 13q and 17p
10.1038/bjc.1997.13 · 1997 · External reference
Mapping of multiple DNA gains and losses in primary small cell lung carcinomas by comparative genomic hybridization
1994 · External reference
Molecular definition of a small amplification domain within 3g26 in tumors of cervix, ovary, and lung
10.1016/s0165-4608(99)00135-1 · 2000 · External reference