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References from Hepatitis Bx Antigen Stimulates Expression of a Novel Cellular Gene, URG4, that Promotes Hepatocellular Growth and Survival. Local targets link to admitted publications; unresolved targets remain external evidence.
Hepatitis B virus and hepatocellular carcinoma
10.1111/j.1365-2613.2001.iep178.x · 2001 · External reference
Epidemiology of hepatocellular carcinoma
1984 · External reference
Estimation of the worldwide incidence of twenty-five major cancers
1999 · External reference
Hepatitis B virus
1988 · External reference
Hepatitis B virus X antigen in the pathogenesis of chronic infections and the development of hepatocellular carcinoma
1997 · External reference
Transactivation of cellular gene expression by hepatitis B viral proteins: a possible molecular mechanism of hepatocarcinogenesis
1995 · External reference
Hepatitis B virus transcriptional activators: mechanisms and possible role in oncogenesis
10.1111/j.1365-2893.1996.tb00001.x · 1996 · External reference
Integration of hepatitis B virus DNA and its implications for hepatocarcinogenesis
1990 · External reference
Hepatitis B X gene expression in hepatocellular carcinoma
10.1016/0168-8278(92)90077-3 · 1992 · External reference
Selective accumulation of the X transcript of hepatitis B virus in patients negative for hepatitis B surface antigen with hepatocellular carcinoma
1995 · External reference
Detection of hepatitis B virus X gene protein and antibody in type B chronic liver disease
10.1016/0016-5085(89)91508-4 · 1989 · External reference
Expression of the X gene product of hepatitis B virus and WHV in infected livers and transfected 3T3 cells: evidence for cross-reactivity and correlation with core/e gene expression
1988 · External reference
Hepatitis B x antigen in hepatitis B virus carrier patients with liver cancer
1991 · External reference
Hepatitis B x antigen in liver from carrier patients with chronic hepatitis and cirrhosis
10.1002/hep.1840140106 · 1991 · External reference
Characteristics of woodchuck hepatitis X antigen in the livers and sera from chronically infected animals
10.1016/s0168-8278(05)80420-9 · 1993 · External reference
High-level expression of hepatitis B virus HBx gene and hepatocarcinogenesis in transgenic mice
10.1002/hep.1840190403 · 1994 · External reference
Functional inactivation but not structural mutation of p53 causes liver cancer
10.1038/ng0195-41 · 1995 · External reference
Malignant transformation of immortalized transgenic hepatocytes after transfection with hepatitis B virus DNA
10.1002/j.1460-2075.1990.tb08220.x · 1990 · External reference
Hepatomaderived integrated HBV DNA causes multi-stage transformation in vitro
1996 · External reference
Hepatitis B virus X-gene product: a promiscuous transcriptional activator
10.1002/jmv.1890360207 · 1992 · External reference
HBV X protein activates ras-GTP complex formation and establishes a ras, raf, MAP kinase signaling cascade
10.1073/pnas.91.22.10350 · 1994 · External reference
Hepatitis B virus protein activates transcription factor NF-nB without a requirement for protein kinase C
10.1128/jvi.66.2.983-991.1992 · 1992 · External reference
Induction of the DNA binding activity of c-Jun/ c-Fos heterodimers by the hepatitis B virus transactivator pX
10.1128/mcb.14.2.989 · 1994 · External reference
HBx protein of hepatitis B virus activates Jaki-STAT signaling
10.1074/jbc.273.39.25510 · 1998 · External reference
Human RPB5, a subunit shared by eukaryotic nuclear RNA polymerases, binds human hepatitis B virus X protein and may play a role in X transactivation
10.1002/j.1460-2075.1995.tb06984.x · 1995 · External reference
Hepatitis B virus transactivator protein X interacts with the TATA-binding protein
10.1073/pnas.92.4.1003 · 1995 · External reference
HBV X protein alters the DNA binding specificity of CREB and ATF-2 by protein-protein interactions
10.1126/science.1827531 · 1991 · External reference
The X protein of hepatitis B virus coactivates potent activation domains
10.1128/mcb.15.2.1079 · 1995 · External reference
pX, the HBV-encoded coactivator, interacts with components of the transcription machinery and stimulates transcription in a TAF-independent manner
10.1002/j.1460-2075.1996.tb00707.x · 1996 · External reference
Hepatitis B virus X protein interacts with a probable cellular DNA repair protein
10.1128/jvi.69.2.1107-1114.1995 · 1995 · External reference
Hepatitis B virus X protein inhibits p53 sequence-specific DNA binding, transcriptional activity and association with ERCC3
10.1073/pnas.91.6.2230 · 1994 · External reference
Hepatitis B x antigen and p53 are associated in vitro and in liver tissues from patients with primary hepatocellular carcinoma
1993 · External reference
Identification and preliminary characterization of a protein involved in cellular senescence which binds to hepatitis B virus X antigen
10.1002/hep.510270135 · 1998 · External reference
Abrogation of negative growth regulatory pathways by hepatitis B virus encoded X antigen in the development of hepatocel lular carcinoma
1999 · External reference
The translation initiation factor, SUIT, may be a target of hepatitis B x antigen in hepatocarcinogenesis
10.1038/sj.onc.1202470 · 1999 · External reference
Hepatitis B virus X protein and p53 tumor suppressor interactions in the modulation of apoptosis
10.1073/pnas.94.26.14707 · 1997 · External reference
X-gene product of hepatitis B virus induces apoptosis in liver cells
10.1074/jbc.273.1.381 · 1998 · External reference
Genetic and functional analysis of the effects of hepatitis B viral transactivator HBx on cell growth and apoptosis: implications for viral replication and hepatocarcinogenesis
1999 · External reference
The hepatitis B virus HBx protein inhibits caspase 3 activity
10.1074/jbc.273.50.33347 · 1998 · External reference
Hepatitis B virus HBx protein deregulates cell cycle checkpoint controls
10.1073/pnas.92.24.11215 · 1995 · External reference
Increased expression of the insulin-like growth factor I (IGF-I) receptor gene in hepatocellular carcinoma cell lines: implications of IGF-I receptor gene activation by hepatitis B virus X gene product
1996 · External reference
Expression of insulin-like growth factor II in hepatitis B, cirrhosis and hepatocellular carcinoma: its relationship with hepatitis B virus antigen expression
10.1002/hep.1840200404 · 1994 · External reference
Expression of the pancreatic secretory trypsin inhibitor gene in the liver infected with hepatitis B virus
10.1016/s0168-8278(05)80610-5 · 1994 · External reference
The X-gene of human hepatitis B virus transactivates the c-jun and alpha-fetoprotein genes
10.1007/bf01310574 · 1994 · External reference
Controlled synthesis of HBxAg in a differentiated human liver carcinoma-derived cell line
10.1038/282615a0 · 1979 · External reference
Production of hepatitis B virus particles in Hep G2 cells transfected with cloned hepatitis B virus DNA
10.1073/pnas.84.4.1005 · 1987 · External reference
Viral vectors for gene expression
1991 · External reference
A cellular gene up-regulated by hepatitis B virus encoded X antigen promotes hepatocellular growth and survival
10.1053/jhep.2001.25545 · 2001 · External reference
Intracellular immunization against HIV-1 infection of human T lymphocytes: utility of anti-Rev single-chain variable fragments
10.1089/hum.1995.6.12-1561 · 1995 · External reference
GenBank
10.1093/nar/25.1.1 · 1997 · External reference
Presence of antibodies to the polymerase gene product(s) of hepatitis B and woodchuck hepatitis virus in natural and experimental infections
10.1002/jmv.1890240202 · 1988 · External reference
Introduction to cancer genes and growth control
2000 · External reference
Tumorigenicity of virus-transformed cells in nude mice is correlated specifically with anchorage independent growth in vitro
10.1073/pnas.72.11.4435 · 1975 · External reference
