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References from STAT6 Mediates Interleukin-4 Growth Inhibition in Human Breast Cancer Cells. Local targets link to admitted publications; unresolved targets remain external evidence.
Granulocyte-macrophage colony-stimulating factor-activated signaling pathways in human neutrophils
1999 · External reference
Interleukin-4 and interleukin-13 inhibit estrogen-induced breast cancer cell proliferation and stimulate GCDFP-15 expression inhuman breast cancer cells
10.1016/0303-7207(96)03843-9 · 1996 · External reference
Prognostic significance of insulin-like growth factor I receptors in human breast cancer
1990 · External reference
LRi regulates c-myc transcription in B-cell lymphomas
10.1073/pnas.91.11.4915 · 1994 · External reference
Interleukin-4 mediates cell growth inhibition through activation of Stati
10.1074/jbc.275.14.10212 · 2000 · External reference
Recombinant human interleukin 4 (IL-4) given as daily subcutaneous injections-a phase I dose toxicity trial
10.1038/bjc.1992.243 · 1992 · External reference
Multiple signaling pathways mediate interleukin-4-induced 3 beta-hydroxysteroid dehydrogenase/delta(5)-delta(4) isomerase type 1 gene expression in human breast cancer cells
2000 · External reference
Multiple cytokines activate phosphatidylinositol 3-kinase in hematopoietic cells
1994 · External reference
The functional synergy between IL-12 and IL-2 involves p38 mitogenactivated protein kinase and is associatd with the augmentation of STAT serine phosphorylation
10.4049/jimmunol.162.8.4472 · 1999 · External reference
Treatment of established renal cancer by tumor cells engineered to secrete interleukin-4
10.1126/science.1948050 · 1991 · External reference
The role of p21 in interferongamma-induced growth inhibition in human breast cancer cells
2000 · External reference
Interleukin-4 inhibits growth and induces apoptosis in human breast cancer cells
1998 · External reference
Unresolved reference
External reference
Cytokine receptor signalling
10.1038/377591a0 · 1995 · External reference
Insulin receptor-substrate1 (IRS-1) is the predominant signaling molecule activated by insulinlike growth factor-I (IGF-I), insulin, and interleukin-4 (IL-4) in estrogen receptor positive human breast cancer cells
10.1074/jbc.273.16.9994 · 1998 · External reference
Suppression of interleukin-1 converting enzyme-mediated cell death by insulin-like growth factor
10.1074/jbc.271.9.5112 · 1996 · External reference
Stat proteins control lymphocyte proliferation by regulating p27k'p1 expression
10.1128/mcb.18.4.1996 · 1998 · External reference
Characterization of the interleukin-4 nuclear activated factor/STAT and its activation independent of the insulin receptor substrate proteins
10.1074/jbc.270.33.19481 · 1995 · External reference
IGFI-induced degradation of insulin receptor substrate-1 is mediated by the 26S proteosome and blocked by phosphatidylinositol 3'-kinase inhibition
10.1128/mcb.20.5.1489-1496.2000 · 2000 · External reference
Enhancement of the insulin-like growth factor pathway by estrogen in human breast cancer cells
10.1210/mend.13.5.0274 · 1999 · External reference
Expression of the insulin-like growth factor I receptor C terminus as a myristylated protein leads to induction of apoptosis in tumor cells
1998 · External reference
How cytokines control immunoglobulin class switching
1995 · External reference
Identification of a STAT6 domain required for IL-4-induced activation of transcription
10.4049/jimmunol.159.3.1255 · 1997 · External reference
Tumour-associated upregulation of the IL-4 receptor complex
1990 · External reference
Requirements for Interleukin-4-induced gene expression and functional characterization of Stat6
10.1128/mcb.16.10.5811 · 1996 · External reference
Expression of high-affinity interleukin-4 receptors on human renal cell carcinoma cells and inhibition of tumor cell growth in vitro by interleukin-4
10.1172/jci116205 · 1993 · External reference
Expression of high-affinity IL-4 receptors on human melanoma, ovarian and breast carcinoma cells
1994 · External reference
Interleukin-4: a prototypic immunoregulatory lymphokine
10.1182/blood.v77.9.1859.1859 · 1991 · External reference
Interleukin-4 signals through two related pathways
10.1073/pnas.92.17.7971 · 1995 · External reference
Extracellular signal-regulated kinase (ERK) interacts with signal transducer and activator of transcription (STAT) 5a
10.1210/mend.13.4.0263 · 1999 · External reference
Expression of high-affinity interleukin 4 receptors on murine sarcoma cells and receptor-mediated cytotoxicity of tumor cells to chimeric protein between interleukin 4 and Pseudomonas exotoxin
1991 · External reference
Interleukin 4 targeting of immunoglobulin heavy chain class-switch recombination
10.1016/s0923-2494(05)80006-9 · 1993 · External reference
Optimized assays for quantifying transient expression of co-transfected B-galactosidase and CAT-reporter genes
1992 · External reference
Growth inhibition signalled through the interleukin-4/interleukin-13 receptor complex is associated with tyrosine phosphorylation of insulin receptor substrate-1
10.1042/bj3150767 · 1996 · External reference
Murine interleukin-4 displays potent anti-tumor activity in vivo
10.1016/0092-8674(89)90925-2 · 1989 · External reference
Inhibition of colon and breast carcinoma cell growth by interleukin-4
1992 · External reference
Recombinant human interleukin 4 has antiproliferative activity on human tumor cell lines derived from epithelial and nonepithelial histologies
1995 · External reference
Interleukin 4 receptor expression on human lung tumours and normal lung
1991 · External reference
A phase II study of recombinant human interleukin-4 for advanced or recurrent non-small cell lung cancer
1998 · External reference
Induction of germ-line gamma 1 and epsilon Ig gene expression in murine B cells
1995 · External reference
Insulin receptor substrate-2 is the major 170-kDa protein phosphorylated on tyrosine in response to cytokines in murine lymphohematopoietic cells
10.1074/jbc.272.2.1377 · 1997 · External reference
IL-4 induces serine phosphorylation of the STAT6 transactivation domain in B lymphocytes
10.1016/s0161-5890(00)00088-2 · 2000 · External reference
IL-4 protects cells from apoptosis via the insulin receptor substrate pathway and a second independent signaling pathway
10.4049/jimmunol.157.11.4926 · 1996 · External reference
