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Unresolved reference

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10.1002/ana.410410204 · 1997 · External reference

Homozygous inactivation of the NF1 gene in bone marrow cells from children with neurofibromatosis type 1 and malignant myeloid disorders

10.1056/nejm199706123362404 · 1997 · External reference

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10.1212/wnl.48.4.1121 · 1997 · External reference

Unresolved reference

1994 · External reference

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10.1016/0092-8674(90)90253-b · 1990 · External reference

Deletions and a translocation interrupt a cloned gene at the neurofibromatosis type 1 locus

10.1016/0092-8674(90)90252-a · 1990 · External reference

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10.1126/science.2134734 · 1990 · External reference

cDNA cloning of the type 1 neurofibromatosis gene: complete sequence of the NF1 gene product

10.1016/0888-7543(91)90017-9 · 1991 · External reference

The protein product of the neurofibromatosis type 1 gene is expressed at highest abundance in neurons, Schwann cells and oligodendrocytes

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Identification and characterization of the neurofibromatosis type 1 gene product

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The neurofibromatosis type 1 gene product, neurofibromin, associates with microtubules

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Differential localization of the neurofibromatosis 1 (NF1) gene product, neurofibromin, with the F-actin or microtubule cytoskeleton during differentiation of telencephalic neurons

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The neurofibromatosis type 1 gene encodes a protein related to GAP

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Aberrant regulation of ras proteins in tumour cells from type 1 neurofibromatosis patients

10.1038/356713a0 · 1992 · External reference

Loss of NF1 results in activation of the Ras signaling pathway and leads to aberrant growth in haematopoietic cells

10.1038/ng0296-144 · 1996 · External reference

Abnormal regulation of mammalian p21'as contributes to malignant tumor growth in von Recklinghausen (type 1) neurofibromatosis

10.1016/0092-8674(92)90407-4 · 1992 · External reference

Loss of neurofibromin is associated with activation of ras/MAPK and P13-K/akt signaling in a neurofibromatosis 1 astrocytoma

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Single cell Ras-GTP analysis reveals altered ras activity in a single population of neurofibroma Schwann cells but not fibroblasts

10.1074/jbc.m001702200 · 2000 · External reference

Developmental regulation of a neuron-specific neurofibromatosis 1 (NF1) isoform

10.1002/1531-8249(199911)46:5<777::aid-ana15>3.0.co;2-h · 1999 · External reference

Expression of two new protein isoforms of the neurofibromatosis type 1 gene product, neurofibromin, in muscle tissues

10.1002/aja.1002020309 · 1995 · External reference

A conserved alternative splice in the von Recklinghausen neurofibromatosis (NF1) gene produces two neurofibromin isoforms, both with GAP activity

10.1128/mcb.13.1.487 · 1993 · External reference

Expression of the neurofibromatosis 1 (NF1) isoforms in developing and adult rat tissues

1995 · External reference

Alteration in a new gene encoding a putative membrane-organizing protein causes neurofibromatosis type 2

10.1038/363515a0 · 1993 · External reference

A novel moesin-, ezrin-, radixin-like gene is a candidate for the neurofibromatosis 2 tumor suppressor

10.1016/0092-8674(93)90406-g · 1993 · External reference

ERMMerlin and EBP50 protein families in plasma membrane organization and function

10.1146/annurev.cellbio.16.1.113 · 2000 · External reference

Alternative splicing of the NF2 gene and its mutation analysis of breast and colorectal cancers

10.1093/hmg/3.4.565 · 1994 · External reference

Alternative transcripts in the mouse neurofibromatosis type 2 (NF2) gene are conserved and code for schwannomins with distinct C-terminal domains

10.1093/hmg/3.7.1075 · 1994 · External reference

Expression of the neurofibromatosis 2 (NF2) gene isoforms during rat embryonic development

10.1093/hmg/4.3.471 · 1995 · External reference

Impaired interaction of naturally occurring mutant NF2 protein with actin-based cytoskeleton and membrane

10.1093/hmg/7.2.217 · 1998 · External reference

Impairment of cell adhesion by expression of the mutant neurofibromatosis type 2 (NF2) genes which lack exons in the ERM-homology domain

10.1038/sj.onc.1202010 · 1998 · External reference

Interdomain binding mediates tumor growth suppression by the NF2 gene product

10.1038/sj.onc.1201418 · 1997 · External reference

Defects in neurofibromatosis 2 protein function can arise at multiple levels

10.1093/hmg/7.3.335 · 1998 · External reference

Neurofibromatosis 2 tumor suppressor protein, merlin, forms two functionally important intramolecular associations

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Normal membrane localization and actin association of the NF2 tumor suppressor protein are dependent on folding of its N-terminal domain

10.1242/jcs.114.10.1901 · 2001 · External reference

Structural basis for neurofibromatosis type 2: crystal structure of the merlin FERM domain

2001 · External reference

Merlin differentially associates with the microtubule and actin cytoskeleton

10.1002/(sici)1097-4547(19980201)51:3<403::aid-jnr13>3.0.co;2-7 · 1998 · External reference

Functional analysis of neurofibromatosis 2 (NF2) missense mutations

10.1093/hmg/10.14.1519 · 2001 · External reference

The NF2 tumor suppressor gene product, merlin, mediates contact inhibition of growth through interactions with CD44

10.1101/gad.189601 · 2001 · External reference

The Nf2 tumor suppressor, merlin, functions in Racdependent signaling

10.1016/s1534-5807(01)00009-0 · 2001 · External reference

Merlin phosphorylation by p21-activated kinase 2 and effects of phosphorylation on merlin localization

10.1074/jbc.m200083200 · 2002 · External reference

p21-Activated kinase links Rac/Cdc42 signaling to merlin

10.1074/jbc.c100553200 · 2002 · External reference

Neurofibromatosis 2 tumour suppressor schwannomin interacts with 1311-spectrin

10.1038/ng0498-354 · 1998 · External reference

Neurofibromatosis 2 tumor suppressor protein colocalizes with ezrin and CD44 and associates with actin-containing cytoskeleton

10.1242/jcs.110.18.2249 · 1997 · External reference

NHE-RF, a regulatory cofactor for Na` -H ` exchange, is a common interactor for merlin and ERM (MERM) proteins

10.1074/jbc.273.3.1273 · 1998 · External reference

Assignment of the schwannomin-interacting protein 1 (SCHIPI) gene to human chromosome band 3825 by in situ hybridization and with somatic cell hybrids

10.1159/000048795 · 2001 · External reference

The neurofibromatosis 2 tumor suppressor protein interacts with hepatocyte growth factor-regulated tyrosine kinase substrate

10.1093/hmg/9.11.1567 · 2000 · External reference

Merlin, the neurofibromatosis type 2 gene product, and betas integrin associate in isolated and differentiating Schwann cells

10.1002/(sici)1097-4695(199812)37:4<487::aid-neu1>3.0.co;2-b · 1998 · External reference

Identification of EBP50: a PDZ-containing phosphoprotein that associates with members of the ezrin-radixin-moesin family

10.1083/jcb.139.1.169 · 1997 · External reference

The NF2 interactor, hepatocyte growth factor-regulated tyrosine kinase substrate (HRS), associates with merlin in the "open" conformation and suppresses cell growth and motility

10.1093/hmg/10.8.825 · 2001 · External reference

Ruffling membrane, stress fiber, cell spreading and proliferation abnormalities in human Schwannoma cells

10.1038/sj.onc.1202141 · 1998 · External reference

The neurofibromatosis type 2 gene product, merlin, reverses the F-actin cytoskeletal defects in primary human schwannoma cells

10.1128/mcb.22.4.1150-1157.2002 · 2002 · External reference

Increased expression of the NF2 tumor suppressor gene product, merlin, impairs cell motility, adhesion and spreading

10.1093/hmg/8.2.267 · 1999 · External reference

Mice heterozygous for a mutation at the Nf2 tumor suppressor locus develop a range of highly metastatic tumors

10.1101/gad.12.8.1121 · 1998 · External reference

Targeted disruption of the neurofibromatosis type-1 gene leads to developmental abnormalities in heart and various neural crestderived tissues

10.1101/gad.8.9.1019 · 1994 · External reference

Tumor predisposition in mice heterozygous for a targeted mutation in NFi

10.1038/ng0794-353 · 1994 · External reference

Neurofibromin modulation of ras activity is required for normal endocardial-mesenchymal transformation in the developing heart

10.1242/dev.125.22.4359 · 1998 · External reference

Neurofibromin deficiency in mice causes exencephaly and is a modifier for Splotch neural tube defects

10.1006/dbio.1999.9327 · 1999 · External reference

Schwann cells from neurofibromin-deficient mice exhibit activation of p21-ras, inhibition of cell proliferation and morphological changes

1995 · External reference

Nfi-deficient mouse Schwann cells are angiogenic and invasive and can be induced to hyperproliferate: reversion of some phenotypes by an inhibitor of farsenyl protein transferase

10.1128/mcb.17.2.862 · 1997 · External reference

10.1242/dev.121.11.3583

10.1242/dev.121.11.3583 · External reference

Nfi deficiency causes Ras-mediated granulocyte/macrophage colony stimulating factor hypersensitivity and chronic myeloid leukaemia

10.1038/ng0296-137 · 1996 · External reference

Nfi regulates hematopoietic progenitor cell growth and ras signaling in response to multiple cytokines

10.1084/jem.187.11.1893 · 1998 · External reference

Hyperactivation of p21-ras and the hemato poietic-specific Rho GTPase, Rac2, cooperate to alter the proliferation of neurofibromin-deficient mast cells in vivo and in vitro

10.1084/jem.194.1.57 · 2001 · External reference

Loss of neurofibromin results is neurotrophin-independent survival of embryonic sensory and sympathetic neurons

10.1016/0092-8674(95)90470-0 · 1995 · External reference

P21 ras and phosphatidylinositol-3 kinase are required for survival of wild-type and NF1 mutant sensory neurons

10.1523/jneurosci.18-24-10420.1998 · 1998 · External reference

Neurofibromin negatively regulates neurotrophin signaling through p21-ras in embryonic sensory neurons

10.1006/mcne.2000.0836 · 2000 · External reference

The neurofibromatosis type 1 (Nfi) tumor suppressor is a modifier of carcinoegn-induced pigmentation and papilloma formation in C57BI/ 6 mice

10.1046/j.1523-1747.2000.00994.x · 2000 · External reference

Haploinsufficiency for the neurofibromatosis 1 (NF1) tumor suppressor results in increased astrocyte proliferation

10.1038/sj.onc.1202829 · 1999 · External reference

Neurofibromatosis 1 (NF1) heterozygosity results in a cell-autonomous growth advantage for astrocytes

10.1002/1098-1136(20010315)33:4<314::aid-glia1030>3.0.co;2-q · 2001 · External reference

Heterozygosity for the neurofibromatosis 1 (NF1) tumor suppressor results in abnormalities in cell attachment, spreading and motility in astrocytes

10.1093/hmg/10.26.3009 · 2001 · External reference

The Nfi tumor suppressor regulates mouse skin wound healing, fibroblast proliferation, and collagen deposited by fibroblasts

10.1046/j.1523-1747.1999.00609.x · 1999 · External reference

Genetic and biochemical evidence that haploinsufficiency of the Nfi tumor suppressor gene modulates melanocyte and mast cell fates in vivo

10.1084/jem.191.1.181 · 2000 · External reference

A mouse model for the learning and memory deficits associated with neurofibromatosis type 1

10.1038/ng0397-281 · 1997 · External reference

Mechanism for the learning deficits in a mouse model of neurofibromatosis type 1

10.1038/nature711 · 2002 · External reference

Mouse models of tumor development in neurofibromatosis type 1

10.1126/science.286.5447.2172 · 1999 · External reference

Mouse tumor model for neurofibromatosis type 1

10.1126/science.286.5447.2176 · 1999 · External reference

Nfl;Trp53 mutant mice develop glioblastoma with evidence of strain-specific effects

10.1038/79075 · 2000 · External reference

Learning deficits, but normal development and tumor predisposition, in mice lacking exon 23a of Nfl

10.1038/86898 · 2001 · External reference

Ablation of NF1 function in neurons induces abnormal development of cerebral cortex and reactive gliosis in the brain

10.1101/gad.862101 · 2001 · External reference

Schwann cell hyperplasia and tumors in transgenic mice expressing a naturally occurring mutant NF2 protein

10.1101/gad.13.8.978 · 1999 · External reference

The NF2 tumor suppressor gene product is essential for extraembryonic development immediately prior to gastrulation

10.1101/gad.11.10.1253 · 1997 · External reference

Localization and functional domains of the neurofibromatosis type II tumor suppressor, merlin

1998 · External reference

Analysis of molecular domains of epitope-tagged merlin isoforms in Cos-7 cells and primary rat Schwann cells

10.1006/excr.1997.3843 · 1998 · External reference

PO promoter directs expression of reporter and toxin genes to Schwann cells of transgenic mice

10.1016/0896-6273(92)90279-m · 1992 · External reference

Conditional biallelic Nf2 mutation in the mouse promotes manifestations of human neurofibromatosis type 2

10.1101/gad.14.13.1617 · 2000 · External reference

Astrocytes from forebrain, cerebellum, and spinal cord differ in their responses to vasoactive intestinal peptide

10.1111/j.1471-4159.1988.tb01133.x · 1988 · External reference

Astrocytes exhibit regional specificity in gap-junction coupling

10.1002/glia.440110404 · 1994 · External reference

Uptake of 3H-serotonin and 3H-glutamate by primary astrocyte cultures: II

1992 · External reference

Distinctive growth patterns between cerebral and cerebellar astrocytomas-a tissue culture study

10.1111/j.1365-2559.1981.tb01830.x · 1981 · External reference

Nonrandom chromosomal gains in pilocytic astrocytomas of childhood

10.1016/0046-8177(95)90087-x · 1995 · External reference

Are juvenile pilocytic astrocytomas benign tumors? A cytogenetic study in 24 cases

10.1016/s0165-4608(97)00455-x · 1998 · External reference

Analysis of pilocytic astrocytomas by comparative genomic hybridization

10.1054/bjoc.1999.1066 · 2000 · External reference

Pilocytic astrocytomas do not show most of the genetic changes commonly seen in diffuse astrocytomas

10.1046/j.1365-2559.2000.01005.x · 2000 · External reference

Cancer-related gene expression in neurofibromatosis 1 (NF1)-associated pilocytic astrocytomas

10.1212/wnl.56.7.885 · 2001 · External reference

The PEN5 epitope identifies an oligodendrocyte precursor cell population and pilocytic astrocytomas

10.1016/s0002-9440(10)65228-5 · 1999 · External reference

Comparative gene expression profile analysis of neurofibromatosis 1 (NF1)-associated and sporadic pilocytic astrocytomas

2002 · External reference

Loss of DAL-1, a protein 4.1-related tumor suppressor, is an important early event in the pathogenesis of meningiomas

10.1093/hmg/9.10.1495 · 2000 · External reference

Merlin, DAL-1, and progesterone receptor expression in clinicopathologic subsets of meningioma: a correlative immunohistochemical study of 175 cases

10.1093/jnen/59.10.872 · 2000 · External reference

The protein 4.1 tumor suppressor, DAL-1, impairs cell motility, but regulates proliferation in a cell-type-specific fashion

10.1006/nbdi.2000.0376 · 2001 · External reference

10.1101/gad.226302

10.1101/gad.226302 · External reference