Contact and support
Need help, have a question, or want to contact the ResearchHub team?
© 2026 ResearchHub. Built for responsible scholarly connection.
Research graph
References from Functional Inactivation of pRB Results in Aneuploid Mammalian Cells After Release From a Mitotic Block. Local targets link to admitted publications; unresolved targets remain external evidence.
Aneuploidy and cancer
2000 · External reference
Genetic instabilities in human cancers
10.1038/25292 · 1998 · External reference
Evidence that genetic instability occurs at an early stage of colorectal tumorigenesis
2001 · External reference
Aneuploidy vs
2000 · External reference
Characterization of MAD2B and other mitotic spindle checkpoint genes
10.1006/geno.1999.5831 · 1999 · External reference
Securin is required for chromosomal stability in human cells
10.1016/s0092-8674(01)00340-3 · 2001 · External reference
Correlation of defective mitotic checkpoint with aberrantly reduced expression of MAD2 protein in nasopharyngeal carcinoma cells
10.1093/carcin/21.12.2293 · 2000 · External reference
MAD2 haplo-insufficiency causes premature anaphase and chromosome instability in mammalian cells
10.1038/35053094 · 2001 · External reference
How aneuploidy may cause cancer and genetic instability
1999 · External reference
Genetic instability of cancer cells is proportional to their degree of aneuploidy
10.1073/pnas.95.23.13692 · 1998 · External reference
DNA rereplication in the presence of mitotic spindle inhibitors in human and mouse fibroblasts lacking either p53 or pRb function
1997 · External reference
Entry into mitosis in vertebrate somatic cells is guarded by a chromosome damage checkpoint that reverses the cell cycle when triggered during early but not late prophase
10.1083/jcb.142.4.1013 · 1998 · External reference
Chfr defines a mitotic stress checkpoint that delays entry into metaphase
10.1038/35019108 · 2000 · External reference
Induction of medulloblastomas in p53-null mutant mice by somatic inactivation of Rb in the external granular layer cells of the cerebellum
10.1101/gad.14.8.994 · 2000 · External reference
Fluorescence in situ hybridization with human chromosome-specific libraries: detection of trisomy 21 and translocations of chromosome 4
10.1073/pnas.85.23.9138 · 1988 · External reference
Centrosome duplication in mammalian somatic cells requires E2F and Cdk2-cyclin A
10.1038/10054 · 1999 · External reference
The human papillomavirus type 16 E6 and E7 oncoproteins cooperate to induce mitotic defects and genomic instability by uncoupling centrosome duplication from the cell division cycle
10.1073/pnas.170093297 · 2000 · External reference
Human papillomavirus type 16 E7 oncoprotein-induced abnormal centrosome synthesis is an early event in the evolving malignant phenotype
2001 · External reference
The human papillomavirus E7 oncoprotein can uncouple cellular differentiation and proliferation in human keratinocytes by abrogating p21Cipl-mediated inhibition of cdk2
10.1101/gad.11.16.2101 · 1997 · External reference
Human papillomavirus type 16 E7 oncoprotein binds and inactivates growth-inhibitory insulin-like growth factor binding protein 3
10.1128/mcb.20.17.6483-6495.2000 · 2000 · External reference
Aneuploidy, the somatic mutation that makes cancer a species of its own
10.1002/1097-0169(200010)47:2<81::aid-cm1>3.0.co;2-# · 2000 · External reference
Mutations of mitotic checkpoint genes in human cancers
10.1038/32688 · 1998 · External reference
Managing the centrosome numbers game: from chaos to stability in cancer cell division
10.1016/s0962-8924(00)01872-9 · 2001 · External reference
Characterization of the p53-dependent postmitotic checkpoint following spindle disruption
10.1128/mcb.18.2.1055 · 1998 · External reference
Centrosome duplication
2001 · External reference