Contact and support
Need help, have a question, or want to contact the ResearchHub team?
© 2026 ResearchHub. Built for responsible scholarly connection.
Privacy-aware community infrastructureResearch graph
References from Substrate-specific regulation of the mTORC1 pathway by G protein-coupled receptors. Local targets link to admitted publications; unresolved targets remain external evidence.
Making new contacts: The mTOR network in metabolism and signalling crosstalk
10.1038/nrm3757 · 2014 · External reference
mTOR at the nexus of nutrition, growth, ageing and disease
10.1038/s41580-019-0199-y · 2020 · External reference
AMPK promotes TFEB transcriptional activity through dephosphorylation at both MTORC1-dependent and -independent sites
10.1080/15548627.2026.2629720 · 2026 · External reference
A substrate-specific mTORC1 pathway underlies Birt-Hogg-Dubé syndrome
10.1038/s41586-020-2444-0 · 2020 · External reference
PP2A-dependent TFEB activation is blocked by PIKfyve-induced mTORC1 activity
10.1091/mbc.e21-06-0309 · 2022 · External reference
Spatial and functional separation of mTORC1 signalling in response to different amino acid sources
10.1038/s41556-024-01523-7 · 2024 · External reference
Structure of the lysosomal mTORC1-TFEB-Rag-Ragulator megacomplex
10.1038/s41586-022-05652-7 · 2023 · External reference
Seven-transmembrane receptors
10.1038/nrm908 · 2002 · External reference
The structure and function of G-protein-coupled receptors
10.1038/nature08144 · 2009 · External reference
Heterotrimeric G-proteins: a short history
10.1038/sj.bjp.0706405 · 2006 · External reference
G Protein regulation of MAPK networks
10.1038/sj.onc.1210407 · 2007 · External reference
Structural mechanism of arrestin activation
10.1016/j.sbi.2017.05.001 · 2017 · External reference
Trends in GPCR drug discovery: new agents, targets and indications
10.1038/nrd.2017.178 · 2017 · External reference
GPCR signaling inhibits mTORC1 via PKA phosphorylation of Raptor
10.7554/elife.43038 · 2019 · External reference
G-protein coupled receptor signaling and mammalian target of rapamycin complex 1 regulation
10.1124/molpharm.121.000302 · 2022 · External reference
Expression of G protein-coupled receptors and related proteins in HEK293, AtT20, BV2, and N18 cell lines as revealed by microarray analysis
10.1186/1471-2164-12-14 · 2011 · External reference
Expression of G protein-coupled receptors and related proteins in HEK293, AtT20, BV2, and N18 cell lines as revealed by microarray analysis
10.1186/1471-2164-12-14 · 2011 · External reference
DREADDs (designer receptors exclusively activated by designer drugs): chemogenetic tools with therapeutic utility
10.1146/annurev-pharmtox-010814-124803 · 2015 · External reference
Identification of a regulatory sequence within the third intracellular loop that governs β-arrestin binding to the muscarinic M5 receptor
10.1016/j.cellsig.2025.112004 · 2025 · External reference
SUrface SEnsing of Translation (SUnSET), a method based on western blot assessing protein synthesis rates in vitro
10.21769/bioprotoc.4933 · 2024 · External reference
The complex relationship between TFEB transcription factor phosphorylation and subcellular localization
10.15252/embj.201798804 · 2018 · External reference
GPCR signaling along the endocytic pathway
10.1016/j.ceb.2013.10.003 · 2014 · External reference
Building a better dynasore: the dyngo compounds potently inhibit dynamin and endocytosis
10.1111/tra.12119 · 2013 · External reference
Extensive location bias of the GPCR-dependent translatome via site-selective activation of mTOR
10.1073/pnas.2414738122 · 2025 · External reference
Functionally selective and biased agonists of muscarinic receptors
10.1016/j.phrs.2021.105641 · 2021 · External reference
M3 muscarinic acetylcholine receptor-mediated signaling is regulated by distinct mechanisms
10.1124/mol.107.044750 · 2008 · External reference
Calmodulin enhances mTORC1 signaling by preventing TSC2-Rheb binding
10.1016/j.jbc.2024.108122 · 2025 · External reference
Phosphorylation of TSC2 by PKC-δ reveals a novel signaling pathway that couples protein synthesis to mTORC1 activity
10.1007/s11010-019-03498-8 · 2019 · External reference
Identification of a novel recycling sequence in the C-tail of FPR2/ALX receptor: Association with cell protection from apoptosis
10.1074/jbc.m114.612630 · 2014 · External reference
Formylpeptide receptor 2: nomenclature, structure, signalling and translational perspectives: IUPHAR review 35
10.1111/bph.15919 · 2022 · External reference
The selectivity of beta-adrenoceptor agonists at human beta1-, beta2- and beta3-adrenoceptors
10.1111/j.1476-5381.2010.00754.x · 2010 · External reference
Phosphorylation and functional inactivation of TSC2 by Erk: Implications for tuberous sclerosis and cancer pathogenesis
10.1016/j.cell.2005.02.031 · 2005 · External reference
Spatially distinct pools of TORC1 balance protein homeostasis
10.1016/j.molcel.2018.10.040 · 2019 · External reference
TFEB triggers a matrix degradation and invasion program in triple-negative breast cancer cells upon mTORC1 repression
10.1016/j.devcel.2024.12.005 · 2025 · External reference
Evolving the lock to fit the key to create a family of G protein-coupled receptors potently activated by an inert ligand
10.1073/pnas.0700293104 · 2007 · External reference
Amino acid-mediated intracellular ca2+ rise modulates mtorc1 by regulating the tsc2-rheb axis through ca2+ /calmodulin
10.3390/ijms22136897 · 2021 · External reference
Fiji: an open-source platform for biological-image analysis
10.1038/nmeth.2019 · 2012 · External reference
