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References from SF3B4 ‘reads’ RNA that is methylated by METTL16. Local targets link to admitted publications; unresolved targets remain external evidence.
Where, when, and how: context-dependent functions of RNA methylation writers, readers, and erasers
10.1016/j.molcel.2019.04.025 · 2019 · External reference
m6A modification of U6 snRNA modulates usage of two major classes of pre-mRNA 5′ splice site
10.7554/elife.78808 · 2022 · External reference
Perturbation of m6A writers reveals two distinct classes of mRNA methylation at internal and 5′ sites
10.1016/j.celrep.2014.05.048 · 2014 · External reference
VIRMA mediates preferential m6A mRNA methylation in 3′ UTR and near stop codon and associates with alternative polyadenylation
10.1038/s41421-018-0019-0 · 2018 · External reference
A METTL3–METTL14 complex mediates mammalian nuclear RNA N6-adenosine methylation
10.1038/nchembio.1432 · 2014 · External reference
Mechanistic insights into m6A modification of U6 snRNA by human METTL16
10.1093/nar/gkaa227 · 2020 · External reference
The U6 snRNA m6A methyltransferase METTL16 regulates SAM synthetase intron retention
10.1016/j.cell.2017.05.003 · 2017 · External reference
METTL16 exerts an m6A-independent function to facilitate translation and tumorigenesis
10.1038/s41556-021-00835-2 · 2022 · External reference
HPD is an m6A methyltransferase that protects colorectal cancer cells from ferroptotic cell death by m6A methylating SLC7A11/GPX4
10.1002/advs.202508541 · 2026 · External reference
Targeting FTO suppresses cancer stem cell maintenance and immune evasion
10.1016/j.ccell.2020.04.017 · 2020 · External reference
m6A demethylase ALKBH5 regulates PD-L1 expression and tumor immunoenvironment in intrahepatic cholangiocarcinoma
10.1158/0008-5472.can-21-0468 · 2021 · External reference
A unified model for the function of YTHDF proteins in regulating m6A-modified mRNA
10.1016/j.cell.2020.05.012 · 2020 · External reference
Nuclear m6A reader YTHDC1 regulates mRNA splicing
10.1016/j.molcel.2016.01.012 · 2016 · External reference
YTHDC1 mediates nuclear export of N6-methyladenosine methylated mRNAs
10.7554/elife.31311 · 2017 · External reference
Recognition of RNA N6-methyladenosine by IGF2BP proteins enhances mRNA stability and translation
10.1038/s41556-018-0045-z · 2018 · External reference
SF3B4 regulates chromatin remodeler splicing and Hox expression
10.1016/j.diff.2023.04.004 · 2023 · External reference
The splicing factor SF3B4 drives proliferation and invasion in cervical cancer by regulating SPAG5
10.1038/s41420-022-01120-3 · 2022 · External reference
The role of splicing factor SF3B4 in congenital diseases and tumors
2021 · External reference
Fpocket: an open source platform for ligand pocket detection
10.1186/1471-2105-10-168 · 2009 · External reference
AlphaFold Protein Structure Database in 2024: providing structure coverage for over 214 million protein sequences
10.1093/nar/gkad1011 · 2024 · External reference
SF3b4: a versatile player in eukaryotic cells
10.3389/fcell.2020.00014 · 2020 · External reference
Prevalence and natural history of variants in the ANKRD26 gene: a short review and update of reported cases
10.1080/09537104.2022.2071853 · 2022 · External reference
The oncogene metadherin interacts with the known splicing proteins YTHDC1, Sam68 and T-STAR and plays a novel role in alternative mRNA splicing
10.3390/cancers11091233 · 2019 · External reference
Nuclear m6A reader YTHDC1 regulates alternative polyadenylation and splicing during mouse oocyte development
10.1371/journal.pgen.1007412 · 2018 · External reference
Modeling RNA-Binding protein specificity in vivo by precisely registering protein-RNA crosslink sites
10.1016/j.molcel.2019.02.002 · 2019 · External reference
The role of m6A modification in the biological functions and diseases
10.1038/s41392-020-00450-x · 2021 · External reference
N(6)-methyladenosine (m6A) recruits and repels proteins to regulate mRNA homeostasis
10.1038/nsmb.3462 · 2017 · External reference
SF3B4 promotes ovarian cancer progression by regulating alternative splicing of RAD52
10.1038/s41419-022-04630-1 · 2022 · External reference
SF3B4 plays an oncogenic role in esophageal squamous cell carcinoma
10.21873/anticanres.14272 · 2020 · External reference
The N6-methyladenosine methyltransferase METTL16 enables erythropoiesis through safeguarding genome integrity
10.1038/s41467-022-34078-y · 2022 · External reference
RNA methyltransferase METTL16: from molecular mechanisms to therapeutic prospects in cancers
10.1016/j.canlet.2025.217698 · 2025 · External reference
Genome-wide CRISPR screen identifies splicing factor SF3B4 in driving hepatocellular carcinoma
10.1126/sciadv.adw7181 · 2025 · External reference
Deletion of sf3b4 causes splicing defects and gene dysregulation that disrupt craniofacial development and survival
10.1242/dmm.052169 · 2025 · External reference
Protein domain microarrays as a platform to decipher signaling pathways and the histone code
10.1016/j.ymeth.2019.08.007 · 2020 · External reference
National Center for Biotechnology Information Gene Expression Omnibus GSE255915
External reference
National Center for Biotechnology Information Gene Expression Omnibus GSE255622
External reference
