Research graph
References from Bisecting GlcNAc in N -glycan regulates synaptic maturation. Local targets link to admitted publications; unresolved targets remain external evidence.
Global view of human protein glycosylation pathways and functions
10.1038/s41580-020-00294-x · 2020 · External reference
The biosynthesis of highly branched N-glycans: studies on the sequential pathway and functional role of N-actylglucosaminyltransferases I, II, III, IV, V and VI
10.1016/0300-9084(88)90289-1 · 1988 · External reference
Branched N-glycans and their implications for cell adhesion, signaling and clinical applications for cancer biomarkers and in therapeutics
10.5483/bmbrep.2011.44.12.772 · 2011 · External reference
Negative regulation of T-cell activation and autoimmunity by Mgat5 N-glycosylation
10.1038/35055582 · 2001 · External reference
Suppression of tumor growth and metastasis in Mgat5-deficient mice
10.1038/73163 · 2000 · External reference
Dietary and genetic control of glucose transporter 2 glycosylation promotes insulin secretion in suppressing diabetes
10.1016/j.cell.2005.09.041 · 2005 · External reference
Purification, cDNA cloning, and expression of UDP-N-acetylglucosamine: beta-D-mannoside beta-1,4N-acetylglucosaminyltransferase III from rat kidney
10.1016/s0021-9258(19)37172-8 · 1992 · External reference
Control of glycoprotein synthesis. UDP-GlcNAc: glycopeptide beta 4-N-acetylglucosaminyltransferase III, an enzyme in hen oviduct which adds GlcNAc in beta 1-4 linkage to the beta-linked mannose of the trimannosyl core of N-glycosyl oligosaccharides
10.1016/s0021-9258(18)34010-9 · 1982 · External reference
Control of glycoprotein synthesis. Processing of asparagine-linked oligosaccharides by one or more rat liver Golgi alpha-D-mannosidases dependent on the prior action of UDP-N-acetylglucosamine: alpha-D-mannoside beta 2-N-acetylglucosaminyltransferase I
10.1016/s0021-9258(19)85580-1 · 1980 · External reference
Bisecting GlcNAc is a general suppressor of terminal modification of N-glycan
10.1074/mcp.ra119.001534 · 2019 · External reference
Atomic visualization of a flipped-back conformation of bisected glycans bound to specific lectins
10.1038/srep22973 · 2016 · External reference
Bisecting GlcNAc modification of angiotensin-related glycoproteins in mouse kidney
10.1093/jb/mvaf033 · 2025 · External reference
Epigenetic regulation of neural N -glycomics
10.1002/pmic.201600053 · 2016 · External reference
Expression of alpha1-6 fucosyltransferase in rat tissues and human cancer cell lines
10.1002/(sici)1097-0215(19970917)72:6<1117::aid-ijc29>3.0.co;2-# · 1997 · External reference
An aberrant sugar modification of BACE 1 blocks its lysosomal targeting in Alzheimer's disease
10.15252/emmm.201404438 · 2015 · External reference
Suppression of lung metastasis of B16 mouse melanoma by N-acetylglucosaminyltransferase III gene transfection
10.1073/pnas.92.19.8754 · 1995 · External reference
Bisecting GlcNAc modification stabilizes BACE1 protein under oxidative stress conditions
10.1042/bj20150607 · 2016 · External reference
The addition of bisecting N-acetylglucosamine residues to E-cadherin down-regulates the tyrosine phosphorylation of β-Catenin
10.1074/jbc.m006689200 · 2001 · External reference
Aberrant glycosylation of E-cadherin enhances cell-cell binding to suppress metastasis
10.1074/jbc.271.23.13811 · 1996 · External reference
Introduction of bisecting GlcNAc into integrin α5β1 reduces ligand binding and down-regulates cell adhesion and cell migration
10.1074/jbc.m311627200 · 2004 · External reference
Phytohemagglutinin from Phaseolus vulgaris (PHA-E) displays a novel glycan recognition mode using a common legume lectin fold
10.1093/glycob/cwu004 · 2014 · External reference
Peptide sequence mapping around bisecting GlcNAc-bearing N-glycans in mouse brain
10.3390/ijms22168579 · 2021 · External reference
N-Acetylglucosaminyltransferase (GnT) assays using fluorescent oligosaccharide acceptor substrates: GnT-III, IV, V, and IX (GnT-Vb)
10.1007/978-1-62703-465-4_21 · 2013 · External reference
NeuN, a neuronal specific nuclear protein in vertebrates
10.1242/dev.116.1.201 · 1992 · External reference
Arc, a growth factor and activity-regulated gene, encodes a novel cytoskeleton-associated protein that is enriched in neuronal dendrites
10.1016/0896-6273(95)90299-6 · 1995 · External reference
In vivo and in vitro visualization of gene expression dynamics over extensive areas of the brain
10.1016/j.neuroimage.2008.10.046 · 2009 · External reference
Spine dynamics: are they all the same?
10.1016/j.neuron.2017.08.008 · 2017 · External reference
Sleep promotes the formation of dendritic filopodia and spines near learning-inactive existing spines
10.1073/pnas.2114856118 · 2021 · External reference
HNK-1 (human natural killer-1) glyco-epitope is essential for normal spine morphogenesis in developing hippocampal neurons
10.1016/j.neuroscience.2009.09.065 · 2009 · External reference
Telencephalin slows spine maturation
10.1523/jneurosci.2651-05.2006 · 2006 · External reference
Molecular mechanisms of dendritic spine development and remodeling
10.1016/j.pneurobio.2005.02.003 · 2005 · External reference
Heteromeric AMPA receptors assemble with a preferred subunit stoichiometry and spatial arrangement
10.1016/s0896-6273(01)00520-7 · 2001 · External reference
L1CAM increases MAP2 expression via the MAPK pathway to promote neurite outgrowth
10.1016/j.mcn.2012.03.010 · 2012 · External reference
NCAM-induced neurite outgrowth depends on binding of calmodulin to NCAM and on nuclear import of NCAM and fak fragments
10.1523/jneurosci.0297-10.2010 · 2010 · External reference
Lewis x and α2,3-sialyl glycans and their receptors TAG-1, contactin, and L1 mediate CD24-dependent neurite outgrowth
10.1523/jneurosci.4361-08.2009 · 2009 · External reference
Synaptophysin-dependent synaptobrevin-2 trafficking at the presynapse-Mechanism and function
10.1111/jnc.15499 · 2021 · External reference
Synaptic AMPA receptor composition in development, plasticity and disease
10.1038/nrn.2016.37 · 2016 · External reference
The bisecting GlcNAc on N-glycans inhibits growth factor signaling and retards mammary tumor progression
10.1158/0008-5472.can-09-2719 · 2010 · External reference
The cell biology of synaptic plasticity: AMPA receptor trafficking
10.1146/annurev.cellbio.23.090506.123516 · 2007 · External reference
The mouse stargazer gene encodes a neuronal Ca2 + -channel γ subunit
10.1038/1228 · 1998 · External reference
GRIP: a synaptic PDZ domain-containing protein that interacts with AMPA receptors
10.1038/386279a0 · 1997 · External reference
Clustering of AMPA receptors by the synaptic PDZ domain-containing protein PICK1
10.1016/s0896-6273(00)80689-3 · 1999 · External reference
TARP γ-8 controls hippocampal AMPA receptor number, distribution and synaptic plasticity
10.1038/nn1551 · 2005 · External reference
Characterizing the binding and function of TARP γ8-selective AMPA receptor modulators
10.1074/jbc.ra120.014135 · 2020 · External reference
Mechanisms underlying TARP modulation of the GluA1/2-γ8 AMPA receptor
10.1038/s41467-022-28404-7 · 2022 · External reference
TARP γ-8 glycosylation regulates the surface expression of AMPA receptors
10.1042/bj20140806 · 2015 · External reference
Functional roles of the bisecting GlcNAc in integrin-mediated cell adhesion
10.1016/s0076-6879(10)80019-9 · 2010 · External reference
Loss and recovery of Mgat3 and GnT-III mediated E-cadherin N-glycosylation is a mechanism involved in epithelial-mesenchymal-epithelial transitions
10.1371/journal.pone.0033191 · 2012 · External reference
Dendritic spine dynamics are regulated by monocular deprivation and extracellular matrix degradation
10.1016/j.neuron.2004.12.001 · 2004 · External reference
The cell adhesion protein dystroglycan affects the structural remodeling of dendritic spines
10.1038/s41598-022-06462-7 · 2022 · External reference
N-Glycosylation at the SynCAM (synaptic cell adhesion molecule) immunoglobulin interface modulates synaptic adhesion
10.1074/jbc.m110.120865 · 2010 · External reference
Multiple N-linked glycosylation sites critically modulate the synaptic abundance of neuroligin isoforms
10.1016/j.jbc.2023.105361 · 2023 · External reference
Dendritic spine geometry is critical for AMPA receptor expression in hippocampal CA1 pyramidal neurons
10.1038/nn736 · 2001 · External reference
Genesis of dendritic spines: insights from ultrastructural and imaging studies
10.1038/nrn1300 · 2004 · External reference
Dendritic spines and long-term plasticity
10.1038/nrn1649 · 2005 · External reference
Neural functions of bisecting GlcNAc
10.1007/s10719-018-9829-4 · 2018 · External reference
Isolation, characterization and inactivation of the mouse Mgat3 gene: the bisecting N-acetylglucosamine in asparagine-linked oligosaccharides appears dispensable for viability and reproduction
10.1093/glycob/7.1.45 · 1997 · External reference
Deficiency of schnurri-2, an MHC enhancer binding protein, induces mild chronic inflammation in the brain and confers molecular, neuronal, and behavioral phenotypes related to schizophrenia
10.1038/npp.2013.38 · 2013 · External reference
Design and validation of a tool for neurite tracing and analysis in fluorescence microscopy images
10.1002/cyto.a.20022 · 2004 · External reference
Automated analysis of spines from confocal laser microscopy images: application to the discrimination of androgen and estrogen effects on spinogenesis
10.1093/cercor/bhr059 · 2011 · External reference
ColabFold: making protein folding accessible to all
10.1038/s41592-022-01488-1 · 2022 · External reference
AMPA receptors in the synapse turnover by monomer diffusion
10.1038/s41467-019-13229-8 · 2019 · External reference
Shedding of N-acetylglucosaminyltransferase-V is regulated by maturity of cellular N-glycan
10.1038/s42003-022-03697-y · 2022 · External reference
