References

Global public health burden of heart failure: an updated review

10.15420/cfr.2023.05 · 2023 · External reference

Diastolic heart failure: evidence of increased myocardial collagen turnover linked to diastolic dysfunction

10.1161/circulationaha.106.638569 · 2007 · External reference

Engineering cardiac microphysiological systems to model pathological extracellular matrix remodeling

10.1152/ajpheart.00110.2018 · 2018 · External reference

Intramyocardial fibroblast myocyte communication

10.1161/circresaha.109.207456 · 2010 · External reference

Complex relationship between cardiac fibroblasts and cardiomyocytes in health and disease

10.1161/jaha.120.019338 · 2021 · External reference

Kdm2a deficiency in macrophages enhances thermogenesis to protect mice against HFD-induced obesity by enhancing H3K36me2 at the Pparg locus

10.1038/s41418-020-00714-7 · 2021 · External reference

Epigenetic regulation in cardiovascular disease: mechanisms and advances in clinical trials

10.1038/s41392-022-01055-2 · 2022 · External reference

Histone methyltransferase G9a is required for cardiomyocyte homeostasis and hypertrophy

10.1161/circulationaha.117.028561 · 2017 · External reference

Enhancer of zeste homolog-2 (EZH2) methyltransferase regulates transgelin/smooth muscle-22alpha expression in endothelial cells in response to interleukin-1beta and transforming growth factor-beta2

10.1016/j.cellsig.2015.04.008 · 2015 · External reference

Histone demethylase KDM2A is a selective vulnerability of cancers relying on alternative telomere maintenance

10.1038/s41467-023-37480-2 · 2023 · External reference

Molecular pathways underlying cardiac remodeling during pathophysiological stimulation

10.1161/circulationaha.110.942268 · 2010 · External reference

Pathological ventricular remodeling: mechanisms: part 1 of 2

10.1161/circulationaha.113.001878 · 2013 · External reference

Diastolic heart failure–abnormalities in active relaxation and passive stiffness of the left ventricle

10.1056/nejmoa032566 · 2004 · External reference

Cardiac fibroblasts are essential for the adaptive response of the murine heart to pressure overload

10.1172/jci40295 · 2010 · External reference

Genetic lineage tracing defines myofibroblast origin and function in the injured heart

10.1038/ncomms12260 · 2016 · External reference

Systemic injection of AAV9 carrying a periostin promoter targets gene expression to a myofibroblast-like lineage in mouse hearts after reperfused myocardial infarction

10.1038/gt.2016.20 · 2016 · External reference

Fibroblast-specific PRMT5 deficiency suppresses cardiac fibrosis and left ventricular dysfunction in male mice

10.1038/s41467-024-46711-z · 2024 · External reference

Loss of KDM5B ameliorates pathological cardiac fibrosis and dysfunction by epigenetically enhancing ATF3 expression

10.1038/s12276-022-00904-y · 2022 · External reference

NSD2 promotes ventricular remodelling mediated by the regulation of H3K36me2

10.1111/jcmm.13961 · 2019 · External reference

NSD2 promotes pressure overload-induced cardiac hypertrophy via activating circCmiss1/TfR1/ferroptosis signaling

10.1016/j.lfs.2023.121873 · 2023 · External reference

Writing, erasing and reading histone lysine methylations

10.1038/emm.2017.11 · 2017 · External reference

The role of histone H3K36me3 writers, readers and erasers in maintaining genome stability

10.1016/j.dnarep.2022.103407 · 2022 · External reference

Lysine demethylase 2A promotes the progression of ovarian cancer by regulating the PI3K pathway and reversing epithelial-mesenchymal transition

10.3892/or.2018.6888 · 2019 · External reference

Stabilization of nuclear beta-catenin by inhibiting KDM2A mediates cerebral ischemic tolerance

10.1096/fj.202201657 · 2023 · External reference

Maternal Kdm2a-mediated PI3K/Akt signaling and E-cadherin stimulate the morula-to-blastocyst transition revealing crucial roles in early embryonic development

10.1016/j.theriogenology.2023.06.017 · 2023 · External reference

The role of KDM2A and H3K36me2 demethylation in modulating MAPK signaling during neurodevelopment

10.1007/s12264-023-01161-3 · 2024 · External reference

Up-regulation of miR-663a inhibits the cancer stem cell-like properties of glioma via repressing the KDM2A-mediated TGF-β/SMAD signaling pathway

10.1080/15384101.2021.1966962 · 2021 · External reference

A novel STAT3/NFkappaB p50 axis regulates stromal-KDM2A to promote M2 macrophage-mediated chemoresistance in breast cancer

10.1186/s12935-023-03088-1 · 2023 · External reference

The histone demethylase Fbxl11/Kdm2a plays an essential role in embryonic development by repressing cell-cycle regulators

10.1016/j.mod.2014.10.001 · 2015 · External reference

Global regulation of the histone mark H3K36me2 underlies epithelial plasticity and metastatic progression

10.1158/2159-8290.cd-19-1299 · 2020 · External reference

Demethylation of epiregulin gene by histone demethylase FBXL11 and BCL6 corepressor inhibits osteo/dentinogenic differentiation

10.1002/stem.1255 · 2013 · External reference

MiR-134-5p regulates myocardial apoptosis and angiogenesis by directly targeting KDM2A after myocardial infarction

10.1536/ihj.19-468 · 2020 · External reference

CpG islands recruit a histone H3 lysine 36 demethylase

10.1016/j.molcel.2010.04.009 · 2010 · External reference

KDM2 proteins constrain transcription from CpG island gene promoters independently of their histone demethylase activity

10.1093/nar/gkz607 · 2019 · External reference

Loss of USP22 alleviates cardiac hypertrophy induced by pressure overload through HiF1-alpha-TAK1 signaling pathway

10.1016/j.bbadis.2023.166813 · 2023 · External reference

SOAP: short oligonucleotide alignment program

10.1093/bioinformatics/btn025 · 2008 · External reference

The China National GeneBank Sequence Archive (CNSA) 2024 update

10.1093/hr/uhaf036 · 2025 · External reference

HISAT: a fast spliced aligner with low memory requirements

10.1038/nmeth.3317 · 2015 · External reference

Discovering chimeric transcripts in paired-end RNA-seq data by using EricScript

10.1093/bioinformatics/bts617 · 2012 · External reference

rMATS: robust and flexible detection of differential alternative splicing from replicate RNA-seq data

10.1073/pnas.1419161111 · 2014 · External reference

Fast gapped-read alignment with Bowtie 2

10.1038/nmeth.1923 · 2012 · External reference

clusterProfiler: an R package for comparing biological themes among gene clusters

10.1089/omi.2011.0118 · 2012 · External reference