Research graph
References from Elevated sympathetic tone exacerbates myocardial ischemia reperfusion injury through enhancing endothelial cell inflammation and apoptosis in chronic pain mice. Local targets link to admitted publications; unresolved targets remain external evidence.
Widespread pain is a risk factor for cardiovascular mortality: results from the Framingham Heart Study
10.1093/eurheartj/ehz111 · 2019 · External reference
The association between short-term, chronic localized and chronic widespread pain and risk for cardiovascular disease in the UK Biobank
10.1093/eurjpc/zwac127 · 2022 · External reference
Genetic liability to multi-site chronic pain increases the risk of cardiovascular disease
10.1016/j.bja.2023.04.020 · 2023 · External reference
Ropivacaine and celecoxib-loaded injectable composite hydrogel for improved chronic pain-exacerbated myocardial ischemia-reperfusion injury
10.1016/j.jconrel.2025.01.028 · 2025 · External reference
Cellular circuits in the brain and their modulation in acute and chronic pain
10.1152/physrev.00040.2019 · 2020 · External reference
Brain circuits for pain and its treatment
10.1126/scitranslmed.abj7360 · 2021 · External reference
Chronic pain-related changes in cardiovascular regulation and impact on comorbid hypertension in a general population: the Tromsø study
10.1097/j.pain.0000000000001070 · 2018 · External reference
Modulating neuroplasticity for chronic pain relief: noninvasive neuromodulation as a promising approach
10.1038/s12276-025-01409-0 · 2025 · External reference
Apoptosis of endothelial cells precedes myocyte cell apoptosis in ischemia/reperfusion injury
10.1161/01.cir.104.3.253 · 2001 · External reference
Sildenafil prevents endothelial dysfunction induced by ischemia and reperfusion via opening of adenosine triphosphate-sensitive potassium channels: a human in vivo study
10.1161/01.cir.0000155252.23933.2d · 2005 · External reference
Sympathetic neural overdrive, aortic stiffening, endothelial dysfunction, and impaired exercise capacity in severe COVID-19 survivors: a mid-term study of cardiovascular sequelae
10.1161/hypertensionaha.122.19958 · 2023 · External reference
Artery-associated sympathetic innervation drives rhythmic vascular inflammation of arteries and veins
10.1161/circulationaha.119.040232 · 2019 · External reference
Heart rate variability in myocardial infarction and heart failure
10.1016/j.ijcard.2006.11.221 · 2007 · External reference
Cardiac sympathetic denervation to prevent life-threatening arrhythmias
10.1038/nrcardio.2014.19 · 2014 · External reference
The NLRP3 inflammasome: contributions to inflammation-related diseases
10.1186/s11658-023-00462-9 · 2023 · External reference
Role of β adrenergic receptor polymorphisms in heart failure: systematic review and meta-analysis
10.1016/j.ejheart.2007.11.008 · 2008 · External reference
Cardiac telocytes inhibit cardiac microvascular endothelial cell apoptosis through exosomal miRNA-21-5p-targeted cdip1 silencing to improve angiogenesis following myocardial infarction
10.7150/thno.47021 · 2021 · External reference
LPA2 contributes to vascular endothelium homeostasis and cardiac remodeling after myocardial infarction
10.1161/circresaha.122.321036 · 2022 · External reference
Flow-induced reprogramming of endothelial cells in atherosclerosis
10.1038/s41569-023-00883-1 · 2023 · External reference
Sympathetic nerve activity and neuro-inflammation: who is in the driver’s seat?
10.1111/apha.13011 · 2017 · External reference
AMPK attenuation of β-adrenergic receptor-induced cardiac injury via phosphorylation of β-arrestin-1-ser330
10.1161/circresaha.124.324762 · 2024 · External reference
Multicenter, prospective, randomized controlled trial of high-sensitivity cardiac troponin I-guided combination angiotensin receptor blockade and beta-blocker therapy to prevent anthracycline cardiotoxicity: the Cardiac CARE trial
10.1161/circulationaha.123.064274 · 2023 · External reference
NLRP3 inflammasome activation through heart-brain interaction initiates cardiac inflammation and hypertrophy during pressure overload
10.1161/circulationaha.122.060860 · 2023 · External reference
Mechanism and regulation of NLRP3 inflammasome activation
10.1016/j.tibs.2016.09.002 · 2016 · External reference