Research graph
References from RIPK3 promotes G2/M cell cycle arrest in renal tubular epithelial cells for maladaptive kidney repair. Local targets link to admitted publications; unresolved targets remain external evidence.
International Society of Nephrology’s 0by25 initiative for acute kidney injury (zero preventable deaths by 2025): a human rights case for nephrology
10.1016/s0140-6736(15)60126-x · 2015 · External reference
Long-term risk of adverse outcomes after acute kidney injury: a systematic review and meta-analysis of cohort studies using consensus definitions of exposure
10.1016/j.kint.2018.08.036 · 2019 · External reference
Receptor interacting protein kinase-3 determines cellular necrotic response to TNF-alpha
10.1016/j.cell.2009.05.021 · 2009 · External reference
Pathogenesis of lupus nephritis: RIP3 dependent necroptosis and NLRP3 inflammasome activation
10.1016/j.jaut.2019.05.014 · 2019 · External reference
A role for tubular necroptosis in cisplatin-induced AKI
10.1681/asn.2014080741 · 2015 · External reference
RIPK3 orchestrates fatty acid metabolism in tumor-associated macrophages and hepatocarcinogenesis
10.1158/2326-6066.cir-19-0261 · 2020 · External reference
RIP3 translocation into mitochondria promotes mitofilin degradation to increase inflammation and kidney injury after renal ischemia–reperfusion
10.3390/cells11121894 · 2022 · External reference
RIPK3 promotes sepsis-induced acute kidney injury via mitochondrial dysfunction
10.1172/jci.insight.98411 · 2018 · External reference
RIP3 impedes transcription factor EB to suppress autophagic degradation in septic acute kidney injury
10.1038/s41419-021-03865-8 · 2021 · External reference
RIPK3 promotes kidney fibrosis via AKT-dependent ATP citrate lyase
10.1172/jci.insight.94979 · 2018 · External reference
RIPK3 blockade attenuates kidney fibrosis in a folic acid model of renal injury
10.1096/fj.201902544rr · 2020 · External reference
RIPK3-MLKL-mediated necroinflammation contributes to AKI progression to CKD
10.1038/s41419-018-0936-8 · 2018 · External reference
Cell cycle arrest and the evolution of chronic kidney disease from acute kidney injury
10.1093/ndt/gfu230 · 2015 · External reference
Epithelial cell cycle arrest in G2/M mediates kidney fibrosis after injury
10.1038/nm.2144 · 2010 · External reference
Cdc2 regulatory factors
10.1016/0955-0674(94)90060-4 · 1994 · External reference
Oxygen free radicals in ischemic acute renal failure in the rat
10.1172/jci111524 · 1984 · External reference
The CPLANE protein Intu protects kidneys from ischemia–reperfusion injury by targeting STAT1 for degradation
10.1038/s41467-018-03628-8 · 2018 · External reference
PINK1-PRKN/PARK2 pathway of mitophagy is activated to protect against renal ischemia–reperfusion injury
10.1080/15548627.2017.1405880 · 2018 · External reference
Dynamics of necroptosis in kidney ischemia–reperfusion injury
10.3389/fimmu.2023.1251452 · 2023 · External reference
Mixed lineage kinase domain-like protein mediates necrosis signaling downstream of RIP3 kinase
10.1016/j.cell.2011.11.031 · 2012 · External reference
RIPK3 acts as a lipid metabolism regulator contributing to inflammation and carcinogenesis in non-alcoholic fatty liver disease
10.1136/gutjnl-2020-321767 · 2021 · External reference
Necrostatin-1 attenuates renal ischemia and reperfusion injury via meditation of HIF-1α/mir-26a/TRPC6/PARP1 signaling
10.1016/j.omtn.2019.06.025 · 2019 · External reference
Protective effect of dabrafenib on renal ischemia–reperfusion injury in vivo and in vitro
10.1016/j.bbrc.2019.11.105 · 2020 · External reference
Investigation of receptor interacting protein (RIP3)-dependent protein phosphorylation by quantitative phosphoproteomics
10.1074/mcp.m112.019091 · 2012 · External reference
