Research graph
References from Evidence that increased tyrosine phosphorylation causes disassembly of adherens junctions but does not perturb paracellular permeability in Caco-2 cells. Local targets link to admitted publications; unresolved targets remain external evidence.
Phosphorylation and activation of myosin by Rho-associated kinase (Rho-kinase)
10.1074/jbc.271.34.20246 · 1996 · External reference
Functional dissociation of paracellular permeability and transepithelial electrical resistance and disruption of the apical–basolateral intramembrane diffusion barrier by expression of a mutant tight juction membrane protein
10.1083/jcb.134.4.1031 · 1996 · External reference
A dominant mutant of occludin disrupts tight junction structure and function
10.1242/jcs.112.12.1879 · 1999 · External reference
Interaction of junctional adhesion molecule with the tight junction componentes ZO-1, Cingulin, and Occludin
10.1074/jbc.m905251199 · 2000 · External reference
Loss of epithelial differentiation and gain of invasiveness correlates with tyrosine phosphorylation of the E-cadherin/beta-catenin complex in cells transformed with a temperature-sensitive v-SRC gene
10.1083/jcb.120.3.757 · 1993 · External reference
Phenotypic changes and loss of N-CAM-mediated adhesion in transformed embryonic chicken retinal cells
10.1083/jcb.99.6.1944 · 1984 · External reference
Role of tight junctions in establishing and maintaining cell polarity
10.1146/annurev.physiol.60.1.161 · 1998 · External reference
The small GTP-binding protein Rho regulates a phosphatidylinositol 4-phosphate 5-kinase in mammalian cells
10.1016/0092-8674(94)90259-3 · 1994 · External reference
Tight junction proteins
1998 · External reference
Paracellular barrier and junctional protein distribution depend on basolateral extracellular Ca2+in cultured epithelia. Biochim
10.1016/0167-4889(94)90163-5 · 1984 · External reference
Junctional uvomorulin/E-cadherin and phosphotyrosine-modified protein content are correlated with paracellular permeability in Madin–Darby canine kidney (MDCK) epithelia
10.1007/bf00269543 · 1994 · External reference
Increased tyrosine phosphorylation causes redistribution of adherens junction and tight junction proteins and perturbs paracellular barrier function in MDCK epithelia
10.1016/s0171-9335(98)80020-4 · 1998 · External reference
The tight junction protein ZO-1 establishes a link between the transmembrane protein occludin and the actin cytoskeleton
10.1074/jbc.273.45.29745 · 1998 · External reference
Junctional complexes in various epithelia
10.1083/jcb.17.2.375 · 1963 · External reference
Occludin: a novel integral membrane protein localizing at tight junctions
10.1083/jcb.123.6.1777 · 1993 · External reference
Direct association between occludin and ZO-1 and its possible involvement in the localization of occludin at tight junction
10.1083/jcb.127.6.1617 · 1994 · External reference
Cadherins
10.1146/annurev.cb.08.110192.001515 · 1992 · External reference
Independent regulation of adherens and tight junctions by tyrosine phosphorylation in Caco-2 cells
10.1016/s0167-4889(99)00124-x · 1999 · External reference
Identification of 160-kDa polypeptide that binds to the tight junction protein ZO-1
10.1073/pnas.88.8.3460 · 1991 · External reference
The role of the cell adhesion molecule uvomorulin in the formation and maintenance of the epithelial junctional complex
10.1083/jcb.107.4.1575 · 1988 · External reference
Rho GTPases and the actin cytoskeleton
10.1126/science.279.5350.509 · 1998 · External reference
p60v-srccauses tyrosine phosphorylation and inactivation of the N-cadherin-catenin cell adhesion system
10.1002/j.1460-2075.1993.tb05658.x · 1993 · External reference
ZO-3 a novel member of the MAGUK protein family found at the tight junction interacts with ZO-1 and occludin
10.1083/jcb.141.1.199 · 1998 · External reference
Selective inhibition of protein tyrosine phosphatase activities by H2O2and vanadate in vitro
10.1016/0006-291x(92)91123-8 · 1992 · External reference
10.1083/jcb.124.5.729
10.1083/jcb.124.5.729 · External reference
Occludin as a possible determinant of tight junction permeability in endothelial cells
10.1242/jcs.110.14.1603 · 1997 · External reference
Interactions between actin filaments and membranes in quick-frozen and deeply etched hair cells of the chick ear
10.1083/jcb.95.1.249 · 1982 · External reference
Phosphoinositides and calcium as regulators of cellular actin assembly and disassembly
10.1146/annurev.ph.56.030194.001125 · 1994 · External reference
Rapid disruption of epithelial barrier function by Salmonella typhimurium is associated with structural modification of intercellular junctions
10.1128/iai.63.1.356-359.1995 · 1995 · External reference
Molecular characterization of tissue distribution of ZO-2 a tight junction protein homologous to ZO-1 and the Drosophila disc-large tumor supressor protein
10.1083/jcb.124.6.949 · 1994 · External reference
Structural and functional regulation of tight junction by RhoA and Rac1 small GTPases
10.1083/jcb.142.1.101 · 1998 · External reference
1,25-dihydroxyvitamin D3 but not TPA activates PLD in caco-2 cells via pp60(c-src) and Rho
1999 · External reference
Regulation of myosin phsophatase by Rho and Rho-associated kinase (Rho-kinase)
10.1126/science.273.5272.245 · 1996 · External reference
Disruption of epithelial tight junctions is prevented by cyclic nucleotide-dependent protein kinase inhibitors
10.1007/s004180000143 · 2000 · External reference
Cleavage of structural proteins during the assembly of the head of the bacteriophage T4
10.1038/227680a0 · 1970 · External reference
Effect of FCCP on tight junction permeability and cellular distribution of ZO-1 protein in epithelial (MDCK) cells
10.1016/0005-2736(90)90306-9 · 1990 · External reference
Intestinal absortive cell tight junctions are linked to cytoskeleton
10.1152/ajpcell.1987.253.1.c171 · 1987 · External reference
Functional coupling of tight junction and microfilaments in T84 monolayers
1988 · External reference
Regulation of the movement of solutes across tight junctions
10.1146/annurev.physiol.60.1.143 · 1998 · External reference
Down-regulation of E-cadherin expression in Madin Darby canine kidney (MDCK) cells inside tumors of nude mice
10.1002/ijc.2910470623 · 1991 · External reference
Rho-kinase phosphorylates COO-terminal threonines of ezrin/radixin/moesin (ERM) proteins and regulates their head-to-tail association
10.1083/jcb.140.3.647 · 1998 · External reference
Molecular architecture of tight junction
10.1146/annurev.physiol.60.1.121 · 1998 · External reference
Effects of tumor promoters on LL-PK1renal epithelial tight junctions and transepithelial fluxes
10.1152/ajpcell.1986.251.4.c597 · 1986 · External reference
Effects of diacylglycerols on LLC-PK1renal epithelial: similarity to phorbol ester tumor promotors
10.1002/jcp.1041340306 · 1988 · External reference
Rho protein regulates tight junctions and perijunctional actin organization in polarized epithelia
10.1073/pnas.92.23.10629 · 1995 · External reference
Tight junctions are membrane microdomains
10.1242/jcs.113.10.1771 · 2000 · External reference
Tumor promoters-induced changes in the permeability of epithelial cell tight junction
10.1016/0092-8674(81)90274-9 · 1981 · External reference
Oxidant-induced disruption of intestinal epithelial barrier function: role of protein tyrosine phosphorylation
1997 · External reference
Peroxovanadate induces tyrosine phosphorylation of multiple signaling proteins in mouse liver and kidney
10.1074/jbc.272.2.1263 · 1977 · External reference
Occludin-deficient embryonic stem cells can differentiate into polarized epithelial cells bearing tight junction
10.1083/jcb.141.2.397 · 1998 · External reference
Possible involvement of phosphorylation of occludin in tight junction formation
10.1083/jcb.137.6.1393 · 1997 · External reference
Rho proteins play a critical role in cell migration during the early phase of mucosal restitution
10.1172/jci119515 · 1997 · External reference
Evidence that phosphorylation may increase tight junction permeability
10.1242/jcs.108.2.609 · 1995 · External reference
Structure and function of intercellular junctions
10.1016/s0074-7696(08)60940-7 · 1974 · External reference
Subcellular distribution of small GTP-binding proteins in the intestinal cell line Caco-2
10.1111/j.1365-2362.1995.tb01959.x · 1995 · External reference
Regulation of paracellular permeability in Caco-2 cell monolayer by protein kinase
1993 · External reference
Identification of ZO-1: a high molecular weight polypeptide associated with the tight junction (Zonula occludens) in a variety of epithelia
10.1083/jcb.103.3.755 · 1986 · External reference
Concentration-dependent effects of cytochalasin D on tight junctions and actin filaments in MDCK epithelial cells
10.1242/jcs.107.3.367 · 1994 · External reference
Electrophoretic transfer of protein from polyacrylamide gels to nitrocellulose sheets: procedure and applications
10.1073/pnas.76.9.4350 · 1979 · External reference
Inhibiting cadherin function by dominant mutant E-cadherin expression increases the extent of tight junction assembly
10.1242/jcs.113.6.985 · 2000 · External reference
Occludin confers adhesiveness when expressed in fibroblasts
10.1242/jcs.110.9.1113 · 1997 · External reference
Modulation of intercellular adherens-type junctions and tyrosine phosphorylation of their components in RSV-transformed cultured chick lens cells
10.1091/mbc.2.2.105 · 1991 · External reference
The effect of tyrosine-specific protein phosphorylation on the assembly of adherens-type junctions
10.1002/j.1460-2075.1992.tb05225.x · 1992 · External reference
Induction of polarized cell–cell association and retardation of growth by activation of the E-cadherin–catenin adhesion system in a dispersed carcinoma line
1994 · External reference
Protein interactions at the tight junction. Actin has multiple binding parterns and ZO-1 form independent complexes with ZO-2 and ZO-3
1999 · External reference
