Research graph
References from Renal Function, Appendicular Lean Mass, and Bone Stiffness: Indirect Associations Through Fibroblast Growth Factor 21. Local targets link to admitted publications; unresolved targets remain external evidence.
Global, regional, and national burden of chronic kidney disease in adults, 1990–2023, and its attributable risk factors: a systematic analysis for the Global Burden of Disease Study 2023
10.1016/s0140-6736(25)01853-7 · 2025 · External reference
Cardiovascular disease in chronic kidney disease
10.1161/circulationaha.120.050686 · 2021 · External reference
Sarcopenia in chronic kidney disease: a narrative review from pathophysiology to therapeutic approaches
10.3390/biomedicines13020352 · 2025 · External reference
Skeletal muscle complications in chronic kidney disease
10.1007/s11914-022-00751-w · 2022 · External reference
Management of osteoporosis in CKD
10.2215/cjn.11031017 · 2018 · External reference
High prevalence of sarcopenia, osteoporosis and osteosarcopenia in patients with chronic kidney disease compared with healthy controls
10.1007/s00198-026-08008-3 · 2026 · External reference
Association of sarcopenia with mortality and end-stage renal disease in those with chronic kidney disease: a UK Biobank study
10.1002/jcsm.12705 · 2021 · External reference
Bone mineral density and all-cause mortality in patients with nondialysis chronic kidney disease: results from KNOW-CKD study
10.3390/jcm12051850 · 2023 · External reference
The therapeutic potential of FGF21 in metabolic diseases: from bench to clinic
10.1038/s41574-020-0386-0 · 2020 · External reference
Regulation of longevity by FGF21: interaction between energy metabolism and stress responses
10.1016/j.arr.2017.05.004 · 2017 · External reference
Fibroblast growth factor 21: a regulator of metabolic disease and health span
10.1152/ajpendo.00101.2017 · 2017 · External reference
Serum levels of fibroblast growth factor-21 are increased in chronic and acute renal dysfunction
10.1111/cen.12380 · 2014 · External reference
Regulation and potential biological role of fibroblast growth factor 21 in chronic kidney disease
10.3389/fphys.2021.764503 · 2021 · External reference
Increased fibroblast growth factor-21 in chronic kidney disease is a trade-off between survival benefit and blood pressure dysregulation
10.1038/s41598-019-55643-4 · 2019 · External reference
Skeletal muscle and bone - emerging targets of fibroblast growth factor-21
10.3389/fphys.2021.625287 · 2021 · External reference
Association between fibroblast growth factor 21 and bone mineral density in adults
10.1007/s12020-017-1507-y · 2018 · External reference
Association between serum FGF21 level and sarcopenia in older adults
10.1016/j.bone.2021.115877 · 2021 · External reference
Revised equations for estimated GFR from serum creatinine in Japan
10.1053/j.ajkd.2008.12.034 · 2009 · External reference
GFR estimation using standardized serum cystatin C in Japan
10.1053/j.ajkd.2012.07.007 · 2013 · External reference
Performance of GFR equations in Japanese subjects
10.1007/s10157-012-0704-5 · 2013 · External reference
KDIGO 2024 clinical practice guideline for the evaluation and management of chronic kidney disease
10.1016/j.kint.2023.10.018 · 2024 · External reference
Comparison between dual-energy X-ray absorptiometry and bioelectrical impedance analyses for accuracy in measuring whole body muscle mass and appendicular skeletal muscle mass
10.3390/nu10060738 · 2018 · External reference
Reference values and age differences in body composition of community-dwelling older Japanese men and women: a pooled analysis of four cohort studies
10.1371/journal.pone.0131975 · 2015 · External reference
The FNIH sarcopenia project: rationale, study description, conference recommendations, and final estimates
10.1093/gerona/glu010 · 2014 · External reference
Quantitative ultrasound and bone health in elderly people, a systematic review
10.3390/biomedicines11041175 · 2023 · External reference
Quantitative ultrasound in the management of osteoporosis: the 2007 ISCD official positions
10.1016/j.jocd.2007.12.011 · 2008 · External reference
Replacing sedentary time for physical activity on bone density in patients with chronic kidney disease
10.1007/s00774-021-01255-w · 2021 · External reference
Unresolved reference
2022 · External reference
Relationship between cardiorespiratory fitness and blood pressure in young adults: a mediation analysis of body composition
10.1038/hr.2016.177 · 2017 · External reference
Mediation analysis
10.1146/annurev.psych.58.110405.085542 · 2007 · External reference
Circulating fibroblast growth factor 21 links hemodynamics with kidney function in middle-aged and older adults: a mediation analysis
10.1038/s41440-021-00782-3 · 2022 · External reference
Early-stage chronic kidney disease, insulin resistance, and osteoporosis as risk factors of sarcopenia in aged population: the Fourth Korea National Health and Nutrition Examination Survey (KNHANES IV), 2008–2009
10.1007/s00198-014-2745-y · 2014 · External reference
Relationship between moderate to severe kidney disease and hip fracture in the United States
10.1681/asn.2005111194 · 2006 · External reference
Fibroblast growth factor 21 controls mitophagy and muscle mass
10.1002/jcsm.12409 · 2019 · External reference
Inhibition of growth hormone signaling by the fasting-induced hormone FGF21
10.1016/j.cmet.2008.05.006 · 2008 · External reference
Role of fibroblast growth factor 21 (FGF21) in undernutrition-related attenuation of growth in mice
10.1210/en.2011-1909 · 2012 · External reference
Fibroblast growth factor 21 and protein energy wasting in hemodialysis patients
10.1016/j.clnu.2021.01.036 · 2021 · External reference
Fibroblast growth factor 21 promotes bone loss by potentiating the effects of peroxisome proliferator-activated receptor γ
10.1073/pnas.1200797109 · 2012 · External reference
The starvation hormone, fibroblast growth factor-21, extends lifespan in mice
10.7554/elife.00065 · 2012 · External reference
FGF-21 and skeletal remodeling during and after lactation in C57BL/6J mice
10.1210/en.2014-1083 · 2014 · External reference
Lower serum fibroblast growth factor 21 levels are associated with normal lumbar spine bone mineral density in hemodialysis patients
10.3390/ijerph17061938 · 2020 · External reference
