Research graph
References from Off-label drug use in children: prevalence, risks, and regulation. Local targets link to admitted publications; unresolved targets remain external evidence.
Developmental Changes in Pharmacokinetics and Pharmacodynamics
2018 · External reference
Developmental pharmacokinetics
10.1007/978-3-642-20195-0_2 · 2011 · External reference
Children in clinical trials: towards evidence-based pediatric pharmacotherapy using pharmacokinetic-pharmacodynamic modeling
10.1080/17512433.2016.1198256 · 2016 · External reference
Making Medicines Baby Size: The Challenges in Bridging the Formulation Gap in Neonatal Medicine
10.3390/ijms20112688 · 2019 · External reference
Path towards efficient paediatric formulation development based on partnering with clinical pharmacologists and clinicians, a conect4children expert group white paper
10.1111/bcp.14989 · 2022 · External reference
The Need for Pediatric Drug Development
10.1016/j.jpeds.2017.08.011 · 2018 · External reference
Therapeutic orphans–everybody’s business
2006 · External reference
Awareness, knowledge and views of off-label prescribing in children: a systematic review
10.1111/bcp.12750 · 2015 · External reference
Off-label medicine use in children and adolescents: results of a population-based study in Germany
10.1186/1471-2458-13-631 · 2013 · External reference
Europäische Initiative „Better Medicines for Children“
10.1007/s00112-005-1181-7 · 2005 · External reference
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Mandatory requirements for pediatric drug development in the EU and the US for novel drugs-A comparative study
10.3389/fmed.2022.1009432 · 2022 · External reference
Off-Label Medication use in Children, More Common than We Think: A Systematic Review of the Literature
2018 · External reference
Unlicensed and off-label prescription of drugs to children in primary health care: A systematic review
10.1111/jebm.12402 · 2020 · External reference
Two decades of off-label prescribing in children: a literature review
10.1007/s12519-018-0186-y · 2018 · External reference
Unlicensed and Off-Label Drug Use in Children Before and After Pediatric Governmental Initiatives
2015 · External reference
Pediatric Off-Label and Unlicensed Drug Use and Its Implications
10.2174/1574884712666170317161935 · 2017 · External reference
Use of off-label and unlicenced drugs in hospitalised paediatric patients: a systematic review
10.1007/s00228-014-1768-9 · 2015 · External reference
Off-label and unlicensed drug use in children population
10.1016/j.therap.2018.02.002 · 2018 · External reference
Off-Label Prescribing in Pediatric Population-Literature Review for 2012-2022
10.3390/pharmaceutics15122652 · 2023 · External reference
Extent, reasons and consequences of off-labeled and unlicensed drug prescription in hospitalized children: a narrative review
10.1007/s12519-021-00430-3 · 2021 · External reference
Off‑label and unapproved pediatric drug utilization: A meta‑analysis
10.3892/etm.2024.12701 · 2024 · External reference
Can Registration Procedures of Pharmaceuticals Inadvertently Contribute to Off-Label Prescribing in Children?
10.1177/2168479016651470 · 2016 · External reference
Optimizing therapeutic decision-making for off-label medicines use: A scoping review and consensus recommendations for improving practice and research
10.1002/pds.5640 · 2023 · External reference
Regulating pediatric off-label uses of medicines in the EU and USA: challenges and potential solutions : Comparative regulation framework of off label prescriptions in pediatrics: a review
10.1007/s11096-021-01303-5 · 2022 · External reference
The implementation of the guideline for the management of pediatric off-label use of drugs in China: a cross-sectional study
10.21037/tp-24-198 · 2024 · External reference
Guideline for the management of pediatric off-label use of drugs in China (2021)
10.1186/s12887-022-03457-1 · 2022 · External reference
Recommendations on Off-Label Drug Use in Pediatric Guidelines
10.3389/fphar.2022.892574 · 2022 · External reference
Off-Label Medication: From a Simple Concept to Complex Practical Aspects
2021 · External reference
Off-label use of medicines in neonates, infants, children, and adolescents: a joint policy statement by the European Academy of Paediatrics and the European society for Developmental Perinatal and Pediatric Pharmacology
10.1007/s00431-019-03556-9 · 2020 · External reference
It is time to review how unlicensed medicines are used
10.1007/s00228-015-1886-z · 2015 · External reference
Off-Label, but on-Evidence? A Review of the Level of Evidence for Pediatric Pharmacotherapy
10.1002/cpt.2736 · 2022 · External reference
Off-Label Use vs Off-Label Marketing of Drugs: Part 1: Off-Label Use-Patient Harms and Prescriber Responsibilities
10.1016/j.jacbts.2022.12.011 · 2023 · External reference
Paediatric Drug Development and Formulation Design-a European Perspective
10.1208/s12249-016-0558-3 · 2017 · External reference
Ethical Off-label Drug use: Need for a Rethink?
10.1007/s13312-017-1045-y · 2017 · External reference
Unlicensed and off-label uses of medicines: definitions and clarification of terminology
10.1111/bcp.13394 · 2017 · External reference
Defining off-label and unlicensed use of medicines for children: results of a Delphi survey
10.1016/j.phrs.2008.09.007 · 2008 · External reference
Off-label and unlicensed medicine use and adverse drug reactions in children: a narrative review of the literature
10.1007/s00228-011-1097-1 · 2012 · External reference
Adverse drug reactions and off-label and unlicensed medicines in children: A nested case-control study of inpatients in a pediatric hospital
10.1186/1741-7015-11-238 · 2013 · External reference
Adverse drug reactions and off-label drug use in paediatric outpatients
10.1046/j.1365-2125.2002.t01-3-01689.x · 2002 · External reference
Off-label and unlicensed drug utilization in hospitalized children in Fortaleza, Brazil
10.1007/s00228-008-0543-1 · 2008 · External reference
Adverse drug reactions to unlicensed and off-label drugs on paediatric wards: A prospective study
10.1111/j.1651-2227.1999.tb00191.x · 1999 · External reference
The impact of unlicensed and off-label drug use on adverse drug reactions in paediatric patients
10.2165/00002018-200427130-00006 · 2004 · External reference
Off-label prescribing in pediatric outpatients
10.1542/peds.2014-0764 · 2015 · External reference
Reported adverse drug reactions and their determinants in Dutch children outside the hospital
10.1002/pds.843 · 2004 · External reference
Off-label use of medicines in paediatric inpatients at an Australian teaching hospital
10.1111/jpc.12065 · 2013 · External reference
Adverse drug reactions and off-label and unlicensed medicines in children: A prospective cohort study of unplanned admissions to a paediatric hospital
10.1111/bcp.12222 · 2014 · External reference
Off-label and unlicenced medicine administration to paediatric emergency department patients
10.1111/1742-6723.12431 · 2015 · External reference
Off-label and unlicensed medication use and associated adverse drug events in a pediatric emergency department
10.1097/pec.0b013e3181e057e1 · 2010 · External reference
Unlicensed and off-label drug use in an Irish neonatal intensive care unit: a prospective cohort study
10.1111/apa.12541 · 2014 · External reference
Safety and efficacy of off-label and unlicensed medicines in children
2018 · External reference
Is off-label use a risk factor for adverse drug reactions in pediatric patients? A prospective study in an Indian tertiary care hospital
2015 · External reference
Unresolved reference
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Off-label use of drugs in children
10.1542/peds.2013-4060 · 2014 · External reference
Paediatric Medicines in Europe: The Paediatric Regulation-Is It Time for Reform?
10.3389/fmed.2021.593281 · 2021 · External reference
Effects of the Paediatric Regulation funding on the development of off-patent medicines in children
10.3389/fmed.2024.1473862 · 2024 · External reference
Prescribing for off-label use and unauthorized medicines in three paediatric wards in Finland, the status before and after the European Union Paediatric Regulation
10.1111/jcpt.12119 · 2014 · External reference
Effects of the Off-Label Drug Prescription in the Paediatric Population in Spain from the Adoption of the Latest European Regulation: A Pre-Post Study
10.3390/pharmaceutics13040588 · 2021 · External reference
Drug Utilisation and Off-Label Use on a German Neonatal Intensive Care Unit: A Retrospective Cohort Study and 10-Year Comparison
2020 · External reference
10.57598/r252c
10.57598/r252c · External reference
Ten common questions (and their answers) about off-label drug use
10.1016/j.mayocp.2012.04.017 · 2012 · External reference
Evidenzbasierte Off-label-Anwendung von Arzneimitteln bei Kindern und Jugendlichen: Internationales Konsortium von Kinderformularien als Grundlage für die bestverfügbare Evidenz
10.1007/s00112-022-01418-7 · 2022 · External reference
Benefit-Risk Assessment of Off-Label Drug Use in Children: The Bravo Framework
10.1002/cpt.2336 · 2021 · External reference
Development and Evaluation of a Web-Based Paediatric Drug Information System for Germany
2021 · External reference
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Developing a paediatric drug formulary for the Netherlands
10.1136/archdischild-2016-311674 · 2017 · External reference
Off-label prescribing among office-based physicians
10.1001/archinte.166.9.1021 · 2006 · External reference
Off-label use of drugs in neonatal intensive care units
10.1007/s13312-014-0468-y · 2014 · External reference
Unlicensed and off-label drug use in paediatrics in a mother-child tertiary care hospital
10.1093/pch/21.2.83 · 2016 · External reference
Medication errors and adverse drug events in pediatric inpatients
10.1001/jama.285.16.2114 · 2001 · External reference
Unresolved reference
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Over the counter but no longer under the radar–pediatric cough and cold medications
10.1056/nejmp0707400 · 2007 · External reference
Schwerwiegende Nebenwirkungen durch nasales Xylometazolin
10.1007/s00112-013-2926-3 · 2013 · External reference
